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Palliative surgery for gastric cancer

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https://www.readbyqxmd.com/read/29785081/pressurized-intraperitoneal-aerosol-chemotheprapy-after-misdiagnosed-gastric-cancer-case-report-and-review-of-the-literature
#1
Maciej Nowacki, Dariusz Grzanka, Wojciech Zegarski
We report the first application of pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a rescue therapy before palliative D2 gastrectomy combined with liver metastasectomy performed in a 49-year-old woman with peritoneal carcinomatosis who was primarily diagnosed with and underwent surgery for a Krukenberg tumor. The PIPAC procedure was performed with the use of cisplatin at 7.5 mg/m2 and doxorubicin at 1.5 mg/m2 for 30 min at 37 °C. Eight weeks after the PIPAC procedure, the patient underwent open classic D2 gastrectomy with the creation of a Roux-en-Y anastomosis (RNY) combined with liver metastasectomy...
May 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29780653/isolated-superior-mesenteric-vein-tumor-thrombus-in-a-patient-with-gastric-cancer
#2
Barış Özcan, Metin Çevener, Ayşegül Kargı, Mustafa Özdoğan, Alihan Gürkan
Tumor thrombus in the portal vein can rarely originate from gastric cancer via hematogenous spread, with only few case reports published in the literature. Isolated superior mesenteric vein tumor thrombus in gastric cancer has not been previously reported. A 61-year-old male patient who had undergone distal gastrectomy and gastroenterostomy for gastric ulcer 20 years ago was diagnosed with an obstructive tumor originating from the gastroenterostomy anastomosis site on upper gastrointestinal endoscopy that was performed for complaints of fatigue, oral feeding problems, and anemia...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29774937/-application-of-robotic-surgery-to-treat-carcinoma-in-the-remnant-stomach
#3
Feng Qian, Jiajia Liu, Junyan Liu, Junyan Fan, Yongliang Zhao, Yan Shi, Yingxue Hao, Peiwu Yu
OBJECTIVE: To explore the surgical techniques and feasibility of robotic surgery for carcinoma in the remnant stomach(CRS). METHODS: Clinicopathological data of 20 CRS patients undergoing robotic surgery at the Minimally Invasive Center for Gastrointestinal Surgery, Army Medical University Southwest Hospital from November 2012 to October 2017 were retrospectively collected. The surgical methods, procedures, main difficulties, and key techniques were analyzed, and the clinical efficacy was evaluated...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774935/-clinicopathological-characteristics-and-prognosis-analysis-of-217-patients-with-carcinoma-in-the-remnant-stomach
#4
Xiaodong Liu, Zhaojian Niu, Dong Chen, Dongsheng Wang, Liang Lyu, Haitao Jiang, Jian Zhang, Yu Li, Shougen Cao, Yanbing Zhou
OBJECTIVE: To evaluate the clinicopathological features and prognostic factors of carcinoma in the remnant stomach (CRS). METHODS: Clinicopathological data of 217 consecutive CRS patients from January 2000 to March 2017 at Department of Gastrointestinal Surgery, The Affiliated Hospital of Qingdao University were retrospectively analyzed. CRS was defined as the primary cancer arising from the remnant stomach following gastrectomy, regardless of the initial disease or operation, and at no special time interval...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29717344/radical-gastrectomy-after-chemotherapy-may-prolong-survival-in-stage-iv-gastric-cancer-a-korean-multi-institutional-analysis
#5
Ho Seok Seo, Kyo Young Song, Yoon Ju Jung, Seung Man Park, Hae Myung Jeon, Wook Kim, Hyung Min Chin, Jin-Jo Kim, Sung Keun Kim, Kyung Hwa Chun, Jeong Goo Kim, Jun Hyun Lee, Han Hong Lee, Dong Jin Kim, Han Mo Yoo, Chang Hyun Kim, Eun Young Kim, Cho Hyun Park
ABASTRACT: BACKGROUND: Despite the development of newer treatments, the prognosis for patients with stage IV gastric cancer remains grave. This study evaluated the efficacy of gastrectomy following response to chemotherapy in patients with stage IV gastric cancer. METHODS: A total of 419 patients who were diagnosed with stage IV gastric cancer were identified from the multi-institutional Catholic Gastric Cancer Study Group database. The patients were divided into four groups: 212 were in the chemotherapy only (CTx) group, 124 were in the chemotherapy after palliative gastrectomy (G-CTx) group, 23 were in the radical gastrectomy after chemotherapy (CTx-G) group, and 60 were in the best supportive care group...
May 1, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29581681/robot-assisted-mckeown-esophagectomy-is-feasible-after-neoadjuvant-chemoradiation-our-initial-experience
#6
Ashish Goel, Swati H Shah, Veda Padma Priya Selvakumar, Shubha Garg, Kapil Kumar
Neoadjuvant chemoradiation has become the standard of care for esophageal cancer, especially for middle third esophageal lesions and those with squamous histology. Although more and more thoracic surgeons and surgical oncologists have now shifted to video-assisted and robot-assisted thoracoscopic esophagectomy; there is still limited experience for the use of minimal-assisted approaches in patients undergoing surgery after neoadjuvant chemoradiation. Most surgeons have concerns of feasibility, safety, and oncological outcomes as well as issues related to difficult learning curve in adopting robotic esophagectomy in patients after chemoradiation...
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29520154/clinicopathologic-characteristics-and-prognosis-of-proximal-and-distal-gastric-cancer
#7
Xuefeng Yu, Fulan Hu, Chunfeng Li, Qiang Yao, Hongfeng Zhang, Yingwei Xue
Background and objectives: The dismal prognosis of gastric cancer patients is a global problem. We aim to evaluate the clinicopathologic features and prognostic factors of proximal and distal gastric cancer. Materials and methods: Gastric cancer cases diagnosed and treated at the same surgical unit between 2007 and 2010 were reviewed. Follow-up data from all patients were collected for at least 5 years until 2015. A total of 964 patients were studied (distal gastric cancer [DG], n=777 and proximal gastric cancer [PG], n=187)...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29492918/-surgical-treatment-and-prognosis-of-borrmann-type-iiii-gastric-cancer-involving-the-whole-stomach
#8
Ruizeng Dong, Zewei Zhang, Yiming Zhou, Yonghong Hua, Jianmin Guo
OBJECTIVE: To explore the surgical treatment and prognosis of Borrmann type IIII( gastric cancer involving the whole stomach. METHODS: Clinicopathological characteristics and survival data of 223 patients with Borrmann type IIII( gastric cancer involving the whole stomach (defined as the tumor infiltrating 3 regions of the stomach) receiving surgical treatment at the Department of Abdominal Surgery of Zhejiang Cancer Hospital between January 2002 and December 2015 were analyzed retrospectively...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29483439/-indication-of-palliative-gastrojejunostomy-for-unresectable-advanced-gastric-cancer-with-obstruction-from-the-view-point-of-preoperative-inflammatory-biomarkers
#9
Yoshio Oka, Kaoru Okada, Hideki Nagata, Shinichi Yoshioka, Shigeyuki Ueshima, Naozumi Higaki, Hirohito Hayashida, Riichiro Nezu
Palliative surgery for advanced gastric cancer with serious symptoms such as hemorrhage or obstruction may be meaningful in the point of improving quality of life(QOL). However, the meaning of palliative gastrojejunostomy for unresectable gastric cancer with obstruction is controversial. We retrospectively evaluated the effectiveness of gastrojejunostomy for unresectable gastric cancer with obstruction using preoperative inflammatory biomarkers. Blood lymphocyte monocyte ratio(LMR), neu- trophill ymphocyte ratio(NLR)and C-reactive protein/albumin ratio(CAR)were analyzed as inflammatory biomarkers in this study...
February 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29483437/-efficacy-of-palliative-radiotherapy-for-unresectable-advanced-gastric-cancer-with-bleeding
#10
Jun Shibamoto, Yusuke Takashima, Yukino Kawamura, Maiko Nishida, Mie Onishi, Hidekazu Hiramoto, Fumiaki Ochi, Masahiro Tsujiura, Susumu Nakashima, Junshin Fujiyama, Gaku Nishimura, Mamoru Masuyama
Bleeding and obstruction negativelyimpact qualityof life for patients with unresectable advanced gastric cancer. There are several choices against bleeding and obstruction such as surgery, endoscopic therapy, radiotherapy and interventional radiology. We report on an 85-year-old woman with StageIV gastric cancer with tumor bleeding. Radiation therapyof 30 Gyin 10 fractions was performed. Anyadverse events were not confirmed. Bleeding or obstruction did not occur for 7 months after radiation therapy. Palliative radiation therapy to gastric cancer can be a reasonable option for patients with unsuitable general conditions for surgical intervention...
February 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29482082/metastatic-gastric-adenocarcinoma-and-synchronous-carcinoid-tumour-mimicking-appendicitis-a-case-report
#11
Q B Tran, R Mizumoto, S Ratnayake, B Strekozov
INTRODUCTION: Silent metastatic gastric adenocarcinoma presenting as appendicitis is very rare. Rare pathologies may be encountered during common operations such as appendicectomy and an awareness of possible alternative pathological entities would be helpful in a surgeon's wealth of knowledge. PRESENTATION OF CASE: A 63-year-old man presented with a three-day history of acute abdominal pain suggestive of appendicitis. Intra-operatively, a macroscopically inflamed and perforated appendix was found...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29465550/clinical-significance-of-computed-tomography-detected-ascites-in-gastric-cancer-patients-with-peritoneal-metastases
#12
Su Hwan Kim, Young Ho Choi, Ji Won Kim, Sohee Oh, Seohui Lee, Byeong Gwan Kim, Kook Lae Lee
Patients with peritoneal metastases (PM) are generally considered incurable; therefore, the presence of PM is a critical factor in deciding between palliative surgery and curative resection as a therapeutic strategy. Previous studies have not determined the predictive value of ascites detected on computed tomography (CT) for the presence of PM. We aimed to analyze the factors that are associated with PM in patients with CT-detected ascites.A total of 2207 consecutive patients who were diagnosed with gastric cancer between 2004 and 2013 were identified...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29464402/clinical-outcomes-of-minimally-invasive-treatment-for-early-gastric-cancer-in-patients-beyond-the-indications-of-endoscopic-submucosal-dissection
#13
Weon Jin Ko, Yoo Min Kim, In Kyung Yoo, Joo Young Cho
BACKGROUND: Endoscopic submucosal dissection (ESD) with laparoscopic sentinel lymph node dissection (ESN) and endoscopic full-thickness gastric resection with laparoscopic sentinel lymph node dissection (Hybrid-natural orifice transluminal endoscopic surgery, Hybrid-NOTES) are minimally invasive treatment options for early gastric cancer (EGC) beyond the indications of ESD. This study aimed to evaluate the short- and long-term clinical outcomes of ESN and Hybrid-NOTES. METHODS: We retrospectively analyzed patients who had undergone ESN or Hybrid-NOTES for EGC from January 2009 to March 2013...
February 20, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29449732/gastric-metastasis-from-cervix-carcer-a-case-report
#14
L De Cicco, F Crivelli, P Beretta, E Gjoni, A Merlotti, A Starace, G Marzaroli, F Pasta, T Zurleni, A Aguzzi, C Calandra, S Bracelli
Gastric metastasis by solid tumor cancer is a rare event. Concomitant metastases to other organs are frequent, so that this condition is often associated to a poor prognosis. Upper gastrointestinal bleeding and anemia are the most common presenting symptoms. We present the case of a 81 years old women previously treated for cervix carcinoma showing later a stomach metastasis. The patient is alive and disease free 39 months after salvage gastrectomy. A radical surgery in selected patients could be useful for symptom palliation and prolonged survival...
December 2017: Pathologica
https://www.readbyqxmd.com/read/29428109/ca19-9-level-determines-therapeutic-modality-in-pancreatic-cancer-patients-with-para-aortic-lymph-node-metastasis
#15
Tadafumi Asaoka, Atsushi Miyamoto, Sakae Maeda, Naoki Hama, Masanori Tsujie, Masataka Ikeda, Mitsugu Sekimoto, Shoji Nakamori
BACKGROUND: In general, para-aortic lymph node (LN16) metastasis has been considered as a contraindication for pancreatic resection. However, some pancreatic cancer patients with LN16 metastasis have been reported to survive for longer than expected after pancreatectomy. The purpose of this study was to determine whether pancreatic cancer patients with LN16 metastasis might benefit from surgery. METHODS: We retrospectively reviewed 201 consecutive patients with invasive pancreatic ductal adenocarcinoma who underwent surgery at Osaka National Hospital between April 2003 and December 2012...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29394844/-a-case-of-qol-improvement-after-intestinal-stenosis-due-to-peritoneal-dissemination-of-gastric-cancer-in-elderly-patients
#16
Katsumi Shimomura, Yuki Furuke, Yukie Tanaka, Tatsuya Kumano, Syuhei Komatsu, Kenichiro Imura, Jun Ikeda, Fumihiro Taniguchi, Yasuhiro Shioaki, Yoshikazu Nakatsugawa
Nearly 70% of gastric cancer recurrences occur as peritoneal dissemination. Most of the treatment for recurrence of gastric cancer dissemination is chemotherapy; depending on the symptoms and the site of recurrence, palliative bypass surgery may be performed. Intensive treatment is often difficult for elderly patients over 85-years-old. This case was a 91-year-old female who underwent total gastrectomy for gastric cancer(signet-ring cell carcinoma)7years prior. Two years ago, a stenosis due to recurrence was revealed in the small intestine and bypass surgery was performed...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394677/-conversion-therapy-using-etoposide-and-cisplatin-chemotherapy-for-liver-metastases-from-advanced-gastric-mixed-adenoneuroendocrine-carcinoma-a-case-report
#17
Yoko Inaba, Maiko Fujita, Riki Ninomiya, Daijo Hashimoto
Gastric mixed adenoneuroendocrine carcinoma(MANEC)with multiple liver metastases is a rare condition with most data being derived from case reports. We present a case with liver metastases from gastric MANEC that respond remarkably to chemotherapy. Sixty-one-year-old male with severe anemia referred to surgical consultation due to advanced gastric cancer with multiple liver metastases. To relieve uncontrollable tumor bleeding, simple distal gastrectomy for symptom palliation was performed. Based on the tentative diagnosis with gastric poorly differentiated adenocarcinoma, a course of TS-1 and oxaliplatin therapy was administrated...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29358891/long-term-survival-after-gastrectomy-and-metastasectomy-for-gastric-cancer-with-synchronous-bone-metastasis
#18
Young Jin Choi, Dae Hoon Kim, Hye Suk Han, Joung-Ho Han, Seung-Myoung Son, Dong Soo Kim, Hyo Yung Yun
Bone metastasis is a rare event in patients with gastric cancer, but pathologic fracture, paralysis, pain and hematological disorders associated with the bone metastasis may influence the quality of life. We report herein the case of a 53-year-old man who presented with primary remnant gastric cancer with bone metastasis. The patient requested further investigations after detection of a metastatic lesion in the 2nd lumbar vertebra during evaluation for back pain that had persisted for 3 mo. No other metastatic lesions were detected...
January 7, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29275224/staging-and-surgical-approaches-in-gastric-cancer-a-systematic-review
#19
REVIEW
Natalie Coburn, Roxanne Cosby, Laz Klein, Gregory Knight, Richard Malthaner, Joseph Mamazza, C Dale Mercer, Jolie Ringash
BACKGROUND: Gastric adenocarcinoma accounted for 6.8% of new cancer cases and 8.8% of cancer deaths worldwide in 2012. Although resection is the cornerstone for cure, several aspects of surgical intervention remain controversial or sub-optimally applied at the population level. These include staging, extent of lymph node dissection (LND), optimal requirements of LN assessment, minimum resection margins, surgical technique (laparoscopic vs. open), relationship between surgical volumes and patient outcomes, and resection of stage IV gastric cancer...
February 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29216420/erratum-comparison-of-surgery-plus-chemotherapy-and-palliative-chemotherapy-alone-for-advanced-gastric-cancer-with-krukenberg-tumor
#20
Jang Ho Cho, Jae Yun Lim, Ah Ran Choi, Sung Min Choi, Jong Won Kim, Seung Ho Choi, Jae Yong Cho
[This corrects the article on p. 697 in vol. 47.].
January 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
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