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Malignant obstruction

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https://www.readbyqxmd.com/read/29334130/radiofrequency-ablation-combined-with-multiple-biliary-metal-stent-placement-using-short-type-single-balloon-endoscope-in-patients-with-surgically-altered-anatomy
#1
Tadahisa Inoue, Kiyoaki Ito, Masashi Yoneda
Placement of multiple metal stents (MS) for the management of high-grade malignant hilar biliary obstruction (MHBO) is useful,1,2 and biliary radiofrequency ablation (RFA) has been suggested to improve stent patency.3,4 However, to our knowledge, there are no reports of RFA procedures performed using a single-balloon endoscope (SBE) in patients with surgically altered anatomy. Here, we report a successful case of RFA combined with multiple MS placement using SBE in Roux-en-Y gastrectomy. This article is protected by copyright...
January 15, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29334123/cancer-associated-fibroblasts-tailored-tumor-microenvironment-of-therapy-resistance-in-gastrointestinal-cancers
#2
REVIEW
Yeqi Sun, Ruifen Wang, Meng Qiao, Yanchun Xu, Wenbin Guan, Lifeng Wang
Gastrointestinal cancers (GI) are a group of highly aggressive malignancies with heavy cancer-related mortalities. Even if continued development of therapy methods, therapy resistance has been a great obstruction for cancer treatment and thereby inevitably leads to depressed final mortality. Peritumoral cancer associated fibroblasts (CAFs), a versatile population assisting cancer cells to build a facilitated tumor microenvironment (TME), has been demonstrated exerting a promotion influence on cancer proliferation, migration, invasion, metastasis and also therapy resistance...
January 15, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29332405/endoscopic-ultrasound-guided-choledochoduodenostomy-after-a-failed-or-impossible-ercp
#3
Ana María Mora Soler, Alberto Álvarez Delgado, María Concepción Piñero Pérez, Antonio Velasco-Guardado, Marcos Prieto Héctor, Antonio Rodríguez Pérez
INTRODUCTION: Endoscopic ultrasound-guided biliary drainage (EUS-BD) is an alternative to percutaneous trans-hepatic biliary drainage (PTBD) in cases of failed endoscopic retrograde cholangiopancreatography (ERCP). METHODS: This is a retrospective description of six cases of endoscopic ultrasound-guided biliary drainage via choledochoduodenostomy (EUCD), as well as the clinical characteristics, endoscopic procedure, complications and monitoring. RESULTS: All cases had malignant distal biliary obstruction...
January 15, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29331343/irradiation-stents-vs-conventional-metal-stents-for-unresectable-malignant-biliary-obstruction-a-multicentre-trial
#4
Hai-Dong Zhu, Jin-He Guo, Ming Huang, Jian-Song Ji, Hao Xu, Jian Lu, Hai-Liang Li, Wen-Hui Wang, Yu-Liang Li, Cai-Fang Ni, Hai-Bin Shi, En-Hua Xiao, Wei-Fu Lv, Jun-Hui Sun, Ke Xu, Guo-Hong Han, Lin-An Du, Wei-Xin Ren, Mao-Quan Li, Ai-Wu Mao, Hua Xiang, Kai-Xian Zhang, Jie Min, Guang-Yu Zhu, Chang Su, Li Chen, Gao-Jun Teng
BACKGROUND & AIMS: Placement of an irradiation stent has been demonstrated to offer longer patency and survival when compared to an uncovered SEMS in patients with unresectable malignant biliary obstruction (MBO). We aim to further assess the efficacy of an irradiation stent compared to an uncovered SEMS in those patients. METHODS: We performed a randomized, open-label trial of participants with unresectable MBO at 20 centers in China. A total of 328 participants were parallelly allocated into the irradiation stent group (ISG) or the uncovered SEMS group (USG)...
January 10, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29329768/management-of-pediatric-ovarian-torsion-evidence-of-follicular-development-after-ovarian-preservation
#5
Sarah K Walker, Dave R Lal, Kevin P Boyd, Thomas T Sato
PURPOSE: This study reviews contemporary management and follow-up of pediatric ovarian torsion. METHODS: This is a retrospective series of patients from birth to 19 years undergoing operative management of ovarian torsion from 2012 to 2016. RESULTS: We studied 43 girls who underwent 51 operations for ovarian torsion. The median age was 8.3 years. Ultrasound was utilized for diagnosis in 24/29 patients (83%) evaluated in a children's hospital...
January 9, 2018: Surgery
https://www.readbyqxmd.com/read/29327682/analysis-of-implementiation-of-4th-head-and-neck-cancer-awareness-week-in-department-of-otolaryngology-in-mi%C3%A4-dzyleski-hospital-in-warsaw
#6
Karolina Dżaman, Karolina Piskadło-Zborowska, Mirosława Pietniczka-Załęska
INTRODUCTION: The aim of the study was to analyze the profile of patients applying for free preventive examinations within The Forth European Head an Neck Cancer (HNC) Awareness Week in the Department of Otorhynolaryngology in Międzyleski Hospital in Warsaw (ORL MSS). MATERIAL AND METHODS: A media campaign was designed to inform HNC risk patients about the opportunity to receive free preventive examinations in ORL MSS. 225 patients were enrolled to the study. Patient age ranged from 26 to 92 (average 63 years)...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29325513/use-of-methylene-blue-in-the-prevention-of-recurrent-intra-abdominal-postoperative-adhesions
#7
Octavian C Neagoe, Mihaela Ionica, Octavian Mazilu
Objective To evaluate the efficacy of methylene blue in preventing recurrent symptomatic postoperative adhesions. Methods Patients with a history of >2 surgeries for intra-abdominal adhesion-related complications were selected for this study. Adhesiolysis surgery was subsequently performed using administration of 1% methylene blue. The follow-up period was 28.5 ± 11.1 months. Results Data were available from 20 patients (seven men and 13 women) whose mean ± SD age was 51.2 ± 11.4 years. Adhesions took longer to become symptomatic after the first abdominal surgery when the initial pathology was malignant compared with benign...
January 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29325432/risk-factors-for-primary-failure-of-metallic-ureteral-stents-experience-from-a-tertiary-center
#8
Jui-Shan Hsu, Chao-Yuan Huang, Kao-Lang Liu, Po-Ming Chow
INTRODUCTION: We provide primary patency rate of metallic ureteral stents in cancer patients and investigate the factors affecting primary patency. METHODS: All cancer patients who had received metallic stents for malignant ureteral obstruction between July 2009 and November 2012 in our institute were included. No patients were excluded. Patient profiles, imaging studies, and lab data were collected. Patient profiles included age, gender, body height, body weight, body mass index, cancer types, treatment for cancer, response to cancer treatment, methods of stent insertion, and prior ordinary stents...
January 12, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29324681/ppoma-review-epidemiology-aetiopathogenesis-prognosis-and-treatment
#9
REVIEW
Thais Ligiero Braga, Ralph Santos-Oliveira
Generally, pancreatic polypeptide-secreting tumor of the distal pancreas (PPoma) is classified as a rare tumor, and may occur sporadically or be associated in families or with multiple endocrine neoplasia type 1 (NEM 1). It grows slowly, reaching large dimensions at the time of diagnosis and the symptomatology is fundamentally due to the mass effect, causing either non-specific abdominal pain or symptoms suggestive of obstruction of the pancreatic or biliary duct. Therefore, when detected, they are usually malignant, with metastases mainly in the liver...
January 11, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29324374/ileal-gist-presenting-with-bacteremia-and-liver-abscess-a-case-report-and-review-of-literature
#10
Marina Gorelik, Braulio Sabates, Adel Elkbuli, Tony Dunne
INTRODUCTION: Small intestine gastrointestinal stromal tumors can infrequently present with intra-abdominal abscess, perforation, obstruction or fistula. Tumor-small intestine fistula is a rare phenomenon and occurs as a result of GISTs' propensity to cause mucosal ulceration. This allows bacteria from the gut to gain access to the systemic circulation and predisposes the patient to bacteremia and pyogenic liver abscess. PRESENTATION OF CASE: We present a case of a 63-year-old female whose initial symptoms included fever, nausea, vomiting and right upper quadrant pain...
December 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29319035/a-rare-case-of-bronchial-elastosis-an-unusual-presentation-of-an-unexpandable-lung
#11
Raghav Gupta, Hassan Patail, Mohammad R Al-Ajam
Endobronchial obstruction is a known cause of an unexpandable lung. Endobronchial lesions are usually malignant, however benign cause like hemartoma, lipoma, amyloidosis and neuroendocrine tumors are known. We, hereby present the rare cause of bronchial elastosis presenting as right lower lobe lung collapse.
January 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29318103/cecal-volvulus-following-a-right-nephrectomy-for-wilms-tumor-should-we-need-to-close-the-lateral-peritoneum
#12
Mauricio Gonzalez-Urquijo, Christian Ovalle-Chao, Eduardo Flores-Villalba, Ulises de Jesus Garza-Luna, Jose Humberto Velazco-De La Garza, Ulises Garza-Serna
Wilms' tumor (WT) accounts for 90% of all pediatric renal malignant tumors. The most common postoperative complication based on the National Wilms' Tumor Study is small bowel obstruction. We report on a 2-year-old girl with postoperative bowel obstruction following a right nephrectomy for WT. The patient was reintervened 48 hours after surgery and a cecal volvulus was found. Here, we will describe possible causes of this postoperative complication and discuss management.
January 2018: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/29310368/endoscopic-reintervention-for-stent-malfunction-after-stent-in-stent-deployment-for-malignant-hilar-obstruction
#13
Joung Boom Hong, Dae Hwan Kang, Hyeong Seok Nam, Cheol Woong Choi, Hyung Wook Kim, Su Bum Park, Su Jin Kim, Woo Hyeok Choi
Endoscopic bilateral stenting has been increasingly performed for advanced hilar obstruction. As disease progresses, stent malfunction eventually occurs. However, endoscopic reintervention is difficult in these patients. We aimed to evaluate a suitable reintervention procedure for stent malfunction after stent-in-stent (SIS) deployment for malignant hilar obstruction.Among 52 patients with bilateral stenting performed using the SIS method between September 2009 and June 2016, 20 patients with stent malfunction were enrolled in this study...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29310365/ebv-lymphoproliferative-associated-disease-and-primary-cardiac-t-cell-lymphoma-in-a-stk4-deficient-patient-a-case-report
#14
Roya Sherkat, Mohammad Reza Sabri, Bahar Dehghan, Hamid Bigdelian, Nahid Reisi, Nooshin Afsharmoghadam, Hamid Rahimi, Narges Rahmanian, Cristoph Klein
RATIONALE: Primary cardiac lymphoma (PLC) is an extremely uncommon malignancy. PCL is more common in secondary immunodeficient patients. In this report, we describe a unique case of PLC who had been diagnosed as a STK4 deficient patient. This case is the first Primary immunodeficiency (PID) patient developing PCL in the world. PATIENT CONCERNS: An eleven-year-old girl, a known case of PID, was referred to the pediatric cardiology department because of chest pain and dyspnea...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29302736/diagnosing-common-bile-duct-obstruction-comparison-of-image-quality-and-diagnostic-performance-of-three-dimensional-magnetic-resonance-cholangiopancreatography-with-and-without-compressed-sensing
#15
Heejin Kwon, Scott Reid, Dongeun Kim, Sangyun Lee, Jinhan Cho, Jongyeong Oh
PURPOSE: This study aimed to evaluate image quality and diagnostic performance of a recently developed navigated three-dimensional magnetic resonance cholangiopancreatography (3D-MRCP) with compressed sensing (CS) based on parallel imaging (PI) and conventional 3D-MRCP with PI only in patients with abnormal bile duct dilatation. METHODS: This institutional review board-approved study included 45 consecutive patients [non-malignant common bile duct lesions (n = 21) and malignant common bile duct lesions (n = 24)] who underwent MRCP of the abdomen to evaluate bile duct dilatation...
January 4, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29288116/a-study-on-outcome-of-binding-pancreaticogastrostomy-following-pancreaticoduodenectomy-a-prospective-study
#16
Dronacharya Routh, Nishant Pathak, C S Naidu, A K Singh, P P Rao, Priya Ranjan
INTRODUCTION: The type of anastomosis of the pancreas following pancreaticoduodenectomy is often attributed to the reason for pancreatic leak. Results of various randomized trials comparing pancreaticojejunostomy and pancreaticogastrostomy are conflicting one suggesting advantage over the other and vice versa. In this study we intend to critically analyze a novel technique of binding pancreaticogastrostomy following pancreaticoduodenectomy. AIMS AND OBJECTIVES: The aim of this study is to see the outcome of binding pancreaticogastrostomy by evaluating the technical aspects of binding PG and study the incidence of post-operative complications...
December 26, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29283942/destructive-fibrosarcoma-of-the-maxillary-sinus
#17
Adnan Ekinci, Duran Karataş, Abdurrahman Yetiş, Behice Hande Erenler, Muge Ozcan
Paranasal fibrosarcoma of nasal cavity and paranasal sinuses is a very rare malignant tumor. It is usually presented with nasal obstruction and epistaxis. In this clinical report, clinical symptoms, pathogenesis, and treatment principles of a paranasal fibrosarcoma originating from the right maxillary sinus and obstructing the right nasal passage are discussed.A 55-year-old male patient was admitted to the authors clinic with complaints of nasal obstruction and epistaxis lasting for 2 years. Anterior rhinoscopy revealed a mass lesion which obstructed the right nasal passage and caused frequent epistaxis...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29283409/omentin-a-novel-adipokine-in-respiratory-diseases
#18
REVIEW
Yan Zhou, Bo Zhang, Caixia Hao, Xiaoting Huang, Xiaohong Li, Yanhong Huang, Ziqiang Luo
Adipokines, secreted by the adipose tissue, are extensively involved in the regulation and maintenance of various physiological and pathological processes, including insulin sensitivity, energy expenditure, glucose and lipid metabolism, inflammatory activity, neuroendocrine activity, immunity, cancer, homeostasis, angiogenesis, cardiovascular function, breeding and bone metabolism, and all functions of the endocrine-reproductive system axis. Omentin is a recently identified adipokine, which has become a research hotspot due to its pleiotropic effects on various diseases...
December 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29282391/multifocal-mass-lesions-in-autoimmune-pancreatitis
#19
Kazuhiro Suzumura, Etsuro Hatano, Naoki Uyama, Toshihiro Okada, Yasukane Asano, Seikan Hai, Keiji Nakasho, Jiro Fujimoto
A 59-year-old male patient with jaundice was referred to our hospital because of mass lesions in the pancreatic head and tail. An immunological examination revealed an elevated serum IgG4 level. Computed tomography showed two clear boundary mass lesions in the pancreatic head and tail. Magnetic resonance imaging showed that the mass lesions exhibited low intensity on T1-weighted images and iso-intensity on T2-weighted images. Magnetic resonance cholangiopancreatography showed an obstruction of the main pancreatic duct in the pancreatic head and tail...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29282351/marked-18-fuorine-fluorodeoxyglucose-fdg-avidity-of-an-intrapulmonary-typical-carcinoid-tumor-manifesting-as-a-bronchocele-in-an-asymptomatic-middle-aged-woman
#20
Camila Saadé-Yordán, Edward McBurney-Henriquez, Ricardo González-Santoni, Carmen Gurrea-Rosas, José Montalvo-Fitzpatrick, José A Maldonado-Vargas
BACKGROUND Intrapulmonary carcinoid tumors (ICTs) are malignant, slow-growing tumors classified as either: i) typical, less aggressive, well-differentiated tumors or ii) atypical, more aggressive, poorly-differentiated tumors. Most typical carcinoid tumors originate in the central airway and present with symptoms related to bronchial obstruction. In contrast, atypical carcinoids tend to occur more peripherally and are generally detected incidentally as a solitary pulmonary nodule (SPN). Typical carcinoid tumors usually do not exhibit increased metabolic activity on positron emission tomography with 18-fuorine-fluorodeoxyglucose (FDG PET) as would be expected for malignant tumors...
December 28, 2017: American Journal of Case Reports
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