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Xin Zhao, Hao Wu, Baolin Guo, Ruonan Dong, Yusheng Qiu, Peter X Ma
Injectable self-healing hydrogel dressing with multifunctional properties including anti-infection, anti-oxidative and conductivity promoting wound healing process will be highly desired in wound healing application and its design is still a challenge. We developed a series of injectable conductive self-healed hydrogels based on quaternized chitosan-g-polyaniline (QCSP) and benzaldehyde group functionalized poly(ethylene glycol)-co-poly(glycerol sebacate) (PEGS-FA) as antibacterial, anti-oxidant and electroactive dressing for cutaneous wound healing...
January 11, 2017: Biomaterials
Praveen Thokala, Martin Arrowsmith, Edith Poku, Marissa Martyn-St James, Jeff Anderson, Steve Foster, Tom Elliott, Tony Whitehouse
PURPOSE: To estimate the economic impact of a Tegaderm(TM) chlorhexidine gluconate (CHG) gel dressing compared with a standard intravenous (i.v.) dressing (defined as non-antimicrobial transparent film dressing), used for insertion site care of short-term central venous and arterial catheters (intravascular catheters) in adult critical care patients using a cost-consequence model populated with data from published sources. MATERIAL AND METHODS: A decision analytical cost-consequence model was developed which assigned each patient with an indwelling intravascular catheter and a standard dressing, a baseline risk of associated dermatitis, local infection at the catheter insertion site and catheter-related bloodstream infections (CRBSI), estimated from published secondary sources...
September 2016: Journal of Infection Prevention
Marco Righetti, Nicola Palmieri, Oscar Bracchi, Mario Prencipe, Elena Bruschetta, Francesca Colombo, Irene Brenna, Francesca Stefani, Karen Amar, Alfio Scalia, Ferruccio Conte
INTRODUCTION: Catheter-related infections are an important clinical problem in maintenance hemodialysis patients. Catheter-related bloodstream infections have a negative effect on survival, hospitalization and cost of care. Tegaderm™ chlorhexidine gluconate (CHG) dressing may be useful to reduce catheter-related infection rates. METHODS: We performed a study to assess the efficacy of Tegaderm™ CHG dressing for reducing catheter-related infections. We designed a prospective randomized cross-over study with a scheme of two treatments, Tegaderm™ CHG dressing versus standard dressing, and two periods of six months...
September 21, 2016: Journal of Vascular Access
Roy Ventura, Chris O'Loughlin, Boris Vavrik
Since the introduction of sutureless securement products for vascular access devices (VADs), there has been a great deal of discussion of their advantages and disadvantages in comparison with sutures. This includes questions related to VAD securement, patients' comfort, infection control, user-friendliness and potential complications of using the device. The literature review of the available evidence indicates the superiority of the novel sutureless devices in the aforementioned aspects. The authors collected data to further contribute in the analysis of the attributes of these products, namely Statlock™ and Grip-Lok™ (current devices)...
July 28, 2016: British Journal of Nursing: BJN
E C Diaz, J F Corcoran, E K Johnson
This video provides a case report of penis entrapment secondary to excessive skin removal during circumcision. It highlights the technical aspects of pediatric penile reconstruction using autologous split-thickness skin graft (STSG). Key points include: 1. Infection prevention is paramount and antibiotic prophylaxis is routine. 2. The usual harvest site for the STSG is the lateral thigh because of its source of glabrous skin and convenient proximity to the penis. The lateral thigh is also outside of the diapered area, which helps lessen postoperative pain and infectious risks...
June 2016: Journal of Pediatric Urology
Joan Webster, Donna Gillies, Elizabeth O'Riordan, Karen L Sherriff, Claire M Rickard
No abstract text is available yet for this article.
2016: Cochrane Database of Systematic Reviews
Khang T Nguyen, Lauren Shikowitz, Armen K Kasabian, Nicholas Bastidas
BACKGROUND: Keloids represent a challenging problem. Surgical excision remains the definitive treatment for immediate lesion debulking, but recurrence rates are reported to be 45 to 100 percent. The authors present a staged reconstructive approach using a dermal regeneration substrate and epidermal grafting to minimize recurrence and donor-site morbidity. METHODS: Keloids were completely excised down to normal subcutaneous tissue or perichondrium. A bilaminar dermal regeneration matrix was approximated to the entire wound, with the silicone lamina oriented superficially...
July 2016: Plastic and Reconstructive Surgery
M Siddiqui, A Bidaye, E Baird, R Abu-Rajab, A Stark, B Jones, R Ingram, I Anthony
OBJECTIVE: This study compared three methods of surgical wound dressing in patients undergoing primary total hip arthroplasty to determine their effect on wound leakage. METHOD: Total hip arthroplasties were randomised to 3 groups: 2-octyl cyanoacrylate (Dermabond-Ethicon Inc, G) with Opsite (Smith & Nephew; O) [G+O], 2-octyl cyanoacrylate with Tegaderm (3M; T) [G+T], and Opsite without 2-octyl cyanoacrylate [O]. Postoperative wound leakage was assessed and graded daily until discharge, the frequency of the dressing changes was also recorded...
January 2016: Journal of Wound Care
P M Odor, S Bampoe, J Hayward, I Chis Ster, E Evans
This randomised controlled trial investigated the efficacy of Epi-Fix(™) , LockIt Plus(®) and Tegaderm(™) as fixation devices for intrapartum epidural catheters. One hundred and sixty-five women requesting intrapartum epidural analgesia were randomised to receive different fixation devices to secure their epidural catheter. The amount of epidural catheter migration (measured to the nearest 0.5 cm) was analysed for three devices: Epi-Fix (n = 55); LockIt Plus (n = 54); and Tegaderm dressing (n = 51). Median (IQR [range]) catheter migration for Epi-Fix was 1...
March 2016: Anaesthesia
Seda Bilaloglu, Ying Lu, Daniel Geller, John Ross Rizzo, Viswanath Aluru, Esther P Gardner, Preeti Raghavan
Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction during precision grasp. Ten neurologically intact subjects grasped and lifted an instrumented grip device with 18 different frictional surfaces under three conditions: with bare hands or with a thin layer of plastic (Tegaderm) or an additional layer of foam affixed to the fingertips...
March 2016: Journal of Neurophysiology
M Mohiti-Asli, S Saha, S V Murphy, H Gracz, B Pourdeyhimi, A Atala, E G Loboa
This article presents successful incorporation of ibuprofen in polylactic acid (PLA) nanofibers to create scaffolds for the treatment of both acute and chronic wounds. Nanofibrous PLA scaffolds containing 10, 20, or 30 wt % ibuprofen were created and ibuprofen release profiles quantified. In vitro cytotoxicity to human epidermal keratinocytes (HEK) and human dermal fibroblasts (HDF) of the three scaffolds with varying ibuprofen concentrations were evaluated and compared to pure PLA nanofibrous scaffolds. Thereafter, scaffolds loaded with ibuprofen at the concentration that promoted human skin cell viability and proliferation (20 wt %) were evaluated in vivo in nude mice using a full thickness skin incision model to determine the ability of these scaffolds to promote skin regeneration and/or assist with scarless healing...
October 28, 2015: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Annette Jeanes, James Bitmead
The use of vascular access devices (VAD) is common in healthcare provision but there is a significant risk of acquiring an infection. Central venous catheters (CVC) are associated with the highest risk of intravenous catheter-related bloodstream infection (CRBSI). 3M™ Tegaderm™ CHG IV dressing is a semi-permeable transparent adhesive dressing with an integrated gel pad containing chlorhexidine gluconate 2%. This product was reviewed by the National Institute for Health and Care Excellence (NICE) in 2015, recommending that Tegaderm CHG could be used for CVC and arterial line dressings in high-dependency and intensive-care settings...
October 22, 2015: British Journal of Nursing: BJN
Gianluca Leonardi, Giuseppe Finotto, Marinella Talaia, Angelo Nappo, Caterina Dolla, Maria Cristina Di Vico, Davide Diena, Antonio Linsalata, Cesare Guarena, Silvana Barbaro, Luigi Biancone
INTRODUCTION: We describe two measures adopted in hemodialysis outpatient population in order to reduce Central Venous Catheter (CVC) related infections. The first is a nurse staff training in the field project and the second deals with the employment of chlorhexidine-impregnated dressing devices. These actions were performed after high infection rates were observed through a dedicated register. MATERIALS AND METHODS: In the limited assistance dialysis center, direct observation (12/2012-02/2013) quantified the gap between the observed and expected health care behaviour...
September 2015: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
Michelle Jenks, Joyce Craig, William Green, Neil Hewitt, Mick Arber, Andrew Sims
Catheters are widely used for vascular access and for the administration of drugs or fluids in critically ill patients. This exposes patients to an infection risk. Tegaderm chlorhexidine gluconate (CHG) (developed by 3M)-a transparent securement dressing-covers and protects catheter sites and secures devices to the skin. It comprises a transparent adhesive dressing to act as a barrier against external contamination and an integrated gel pad containing an antiseptic agent. The Medical Technologies Advisory Committee (MTAC) at the National Institute for Health and Care Excellence (NICE) selected Tegaderm CHG for evaluation...
April 2016: Applied Health Economics and Health Policy
Hironobu Ueshima, Jun Ariyama, Akira Kitamura
BACKGROUND: We studied the stability of the continuous arterial pressure line (A line) achieved by using a catheter securement device. METHODS: A total of 100 patients requiring an arterial catheter were divided into 2 groups of fixation: (1) fixation achieved by using the SorbaView SHIELD (Centurion Medical Products Corporation, USA) and (2) fixation by using Tegaderm 3 M (TEGADERM 3 M, Japan). We analyzed the stability of the fixation, presence or absence of skin disorders, and the preference by nurses...
July 2015: Masui. the Japanese Journal of Anesthesiology
Douglas R Solway, Mauricio Consalter, Dennis J Levinson
  In a randomized trial of predominantly category II and III skin tears in a population of frail elderly nursing home residents, standard wound care (24 residents) with Xeroform™ and a secondary dressing (Tegaderm™) was compared with a single application of a microbial cellulose membrane Dermafill (27 residents). Outcomes included the time to wound closure, pain reduction, and ease of use. While wound area was slightly larger in the microbial cellulose treated group, the healing time was equivalent to controls...
January 2010: Wounds: a Compendium of Clinical Research and Practice
George Kokosis, Jennifer E Bond, Lei Chen, Licheng Ren, Maria Angelica Selim, Howard Levinson
UNLABELLED: Scar contracture is a debilitating disease that affects many people worldwide. There are currently no effective preventative medi- cal treatments. A pivotal step to attaining the goal of developing a treatment is the testing of anti-scarring agents in preclinical hierarchi- cal animal models of human scarring. METHODS: A 2-cm x 2-cm, full- thickness, excisional wound was created in the rats' mid-scapular area. Three experiments were performed. The first experiment determined the optimal dressing in wound contraction...
November 2011: Wounds: a Compendium of Clinical Research and Practice
Haryanto Haryanto, Tamae Urai, Kanae Mukai, Paulo P Gontijo Filho, Suriadi Suriadi, Junko Sugama, Toshio Nakatani
The purpose of this study was to investigate the effectiveness of Indonesian honey in wound healing compared to Tegaderm hydrocolloid dressing and Manuka honey. Three groups of male mice were treated to produce 2 circular, full-thickness skin wounds on the dorsum. They were then randomly allocated to receive daily Indonesian honey, Manuka honey, or hydrocolloid (control). Macroscopic findings were observed from day 0 to 14 after wounding. Microscopic findings on days 3, 7, 11, and 14 after wounding were obtained...
April 2012: Wounds: a Compendium of Clinical Research and Practice
Chee Tian Ong, Yanzhong Zhang, Raymond Lim, Rebekah Samsonraj, Jeyakumar Masilamani, Tran Hong Ha Phan, Seeram Ramakrishna, Ivor Lim, Irene Kee, Mohammad Fahamy, Vilma Templonuevo, Chwee Teck Lim, Toan Thang Phan
Objective: Nanofibers for tissue scaffolding and wound dressings hold great potential in realizing enhanced healing of wounds in comparison with conventional counterparts. Previously, we demonstrated good fibroblast adherence and growth on a newly developed scaffold, Tegaderm™-Nanofiber (TG-NF), made from poly ɛ-caprolactone (PCL)/gelatin nanofibers electrospun onto Tegaderm (TG). The purpose of this study is to evaluate the performance and safety of TG-NF dressings in partial-thickness wound in a pig healing model...
February 1, 2015: Advances in Wound Care
Andrew J Kerr, Martin Arrowsmith
Exudate plays a vital role in wound healing by providing the wound with nutrients and creating an essential moist wound healing environment. However, high levels of exudate can become problematic and, in some wounds, increased levels of exudate can then become detrimental to wound healing and the surrounding tissue. This increase in exudate can be influenced by a variety of factors and its cause is not always taken into account within a management plan. This article presents the outcomes of a 10-patient case series selected for treatment with Tegaderm Superabsorber (3M) dressing using an exudate management/dressing selection algorithm...
September 2014: British Journal of Community Nursing
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