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https://www.readbyqxmd.com/read/28430007/the-feasibility-and-impact-of-prospective-medication-review-in-the-emergency-department
#1
Billy Sin, Kwong Lau, Richard Tong, Josel Ruiz, Kimberly Sarosky, Robert DiGregorio, Shalom Butel, Sylvie de Souza
OBJECTIVE: We evaluated the feasibility and impact of prospective medication review (PMR) in the emergency department (ED). METHODS: This was a retrospective cohort study of all nonadmitted ED patients who were prescribed medication orders by ED clinicians from September 2014 to September 2015 to determine the time intervals utilized during each step of the medication use process and quantify the number of interventions conducted by the pharmacist and cost avoidance accrued from the interventions...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28425583/sleep-apnea-syndrome-inflammation-and-oxidative-stress-in-hemodialysis-patients
#2
Olga Nikitidou, Euphemia Daskalopoulou, Aikaterini Papagianni, Vassilios Liakopoulos, Aikaterini Michalaki, Foteini Christidou, Paraskevi Argyropoulou, Dimitrios Kirmizis, Georgios Efstratiadis, Pavlos Nikolaidis, Michail Daniilidis, Nicholas Dombros
INTRODUCTION: Sleep apnea syndrome (SAS) is an established cardiovascular risk factor in the general population related to inflammation and oxidative stress and is very common among hemodialysis patients. Cardiovascular disease and its complications is the main cause of death among hemodialysis patients. The aim of the present study was to investigate the role of SAS in the promotion of inflammation and oxidative stress and thus in the augmentation of cardiovascular risk in hemodialysis patients...
April 20, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28425082/discriminating-between-positional-and-non-positional-obstructive-sleep-apnea-using-some-clinical-characteristics
#3
Abderrahim Oulhaj, Sharina Al Dhaheri, Brenda Bin Su, Mohammed Al-Houqani
PURPOSE: The primary objective of this paper was to identify significant factors associated with positional Obstructive Sleep Apnea (POSA) and to provide a clinical tool for discriminating non positional from POSA. Secondary objectives were about estimating the prevalence of POSA, comparing the polysomnographic variables across POSA and non-POSA patients. METHODS: This was a cross sectional study on 278 patients who completed an overnight sleep study for OSA assessment...
April 19, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28424459/development-and-outcomes-of-a-primary-care-based-sleep-assessment-service-in-canterbury-new-zealand
#4
Michael J Epton, Paul T Kelly, Brett I Shand, Sallyanne V Powell, Judith N Jones, Graham R B McGeoch, Michael C Hlavac
Prior to 2007, increasing demand for sleep services, plus inability to adequately triage severity, led to long delays in sleep assessment and accessing continuous positive airway pressure. We established a community sleep assessment service carried out by trained general practices using a standardised tool and overnight oximetry. All cases were discussed at a multi-disciplinary meeting, with four outcomes: severe obstructive sleep apnoea treated with continuous positive airway pressure; investigation with more complex studies; sleep physician appointment; no or non-severe sleep disorder for general practitioner management...
April 19, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28424245/oral-nutrition-in-children-with-bronchiolitis-on-high-flow-nasal-cannula-is-well-tolerated
#5
Anthony Alexander Sochet, Jessica Ann McGee, Tessie Wazeerah October
OBJECTIVES: To determine the incidence of aspiration-related respiratory failure and nutrition interruptions in children with bronchiolitis on high-flow nasal cannula (HFNC) receiving enteral nutrition. METHODS: We performed a single-center, prospective, observational cohort study within a 313-bed tertiary medical center from January through December 2015. We included term children 1 month to 2 years of age without comorbid bacterial pneumonia or chronic medical conditions who were diagnosed with bronchiolitis while receiving HFNC and enteral nutrition...
April 19, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28422976/reactivation-or-transformation-motor-memory-consolidation-associated-with-cerebral-activation-time-locked-to-sleep-spindles
#6
Stuart Fogel, Genevieve Albouy, Bradley R King, Ovidiu Lungu, Catherine Vien, Arnaud Bore, Basile Pinsard, Habib Benali, Julie Carrier, Julien Doyon
Motor memory consolidation is thought to depend on sleep-dependent reactivation of brain areas recruited during learning. However, up to this point, there has been no direct evidence to support this assertion in humans, and the physiological processes supporting such reactivation are unknown. Here, simultaneous electroencephalographic and functional magnetic resonance imaging (EEG-fMRI) recordings were conducted during post-learning sleep to directly investigate the spindle-related reactivation of a memory trace formed during motor sequence learning (MSL), and its relationship to overnight enhancement in performance (reflecting consolidation)...
2017: PloS One
https://www.readbyqxmd.com/read/28422601/degradation-of-resin-restorative-materials-by-streptococcus-mutans-a-pilot-study
#7
Ankit K Gautam, Ruchi Thakur, N D Shashikiran, Singla Shilpy, Nikita Agarwal, Shilpi Tiwari
OBJECTIVE: To evaluate the degradation of three resin based restorative materials by S Mutans. STUDY DESIGN: Class I cavity was prepared in extracted premolars and were randomly divided into 3 groups (Group I - Conventional composite (CC), Group II - Resin Modified GIC and Group III-Giomer). Teeth were then restored by respective restorative material and equally divided in two subgroups (Control and Experimental). Experiment subgroup samples were then incubated in 2 ml of BHI with 1:10 dilution of SM (MTCC-497) grown overnight in BHI whereas control subgroup samples were incubated in BHI without SM...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28421375/obstructive-sleep-apnea-increases-the-risk-of-cardiac-events-after-percutaneous-coronary-intervention-a-meta-analysis-of-prospective-cohort-studies
#8
REVIEW
Hua Qu, Ming Guo, Ying Zhang, Da-Zhuo Shi
PURPOSE: Recent studies have shown an association between obstructive sleep apnea (OSA) and coronary artery disease; however, the association between OSA and cardiac outcomes in patients after percutaneous coronary intervention (PCI) remains undetermined. METHODS: PubMed, EMBASE, and CENTRAL were searched from inception to July 2016 for cohort studies that followed up with patients after PCI, and evaluated their overnight sleep patterns within 1 month for major adverse cardiac events (MACEs) as primary outcomes including cardiac death, non-fatal myocardial infarction (MI), and coronary revascularization and secondary outcomes including re-admission for heart failure and stroke...
April 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28420550/effect-of-a-moderate-caffeine-dose-on-endurance-cycle-performance-and-thermoregulation-during-prolonged-exercise-in-the-heat
#9
Ross E Beaumont, Lewis J James
OBJECTIVES: This study investigated the influence of a moderate caffeine dose on endurance cycle performance and thermoregulation during prolonged exercise in high ambient temperature. DESIGN: Double-blind cross-over study. METHODS: Eight healthy, recreationally active males (mean±SD; age: 22±1 years; body mass: 71.1±8.5kg; VO2peak: 55.9±5.8mLkg(-1)min(-1); Wmax: 318±37W) completed one VO2peak test, one familiarisation trial and two experimental trials...
March 31, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28419371/sleep-a-window-into-autonomic-control-in-children-born-preterm-and-growth-restricted
#10
Stephanie R Yiallourou, Euan M Wallace, Christie Whatley, Alexsandria Odoi, Samantha Hollis, Aidan J Weichard, Jayan Shivanandhan Muthusamy, Suraj Varma, James Cameron, Om Narayan, Rosemary Sc Horne
Study Objectives: Preterm birth and fetal growth restriction (FGR) are both associated with risk of hypertension in adulthood. Mechanisms leading to this pathology are unclear. In children aged 5-12 years, who were born preterm and FGR, we used sleep as a tool to assess autonomic control with assessment of cardiovascular structure and function. Methods: 18 children born preterm and FGR, 15 born preterm with appropriate birth weights (AGA) and 20 AGA term-born children were studied...
April 17, 2017: Sleep
https://www.readbyqxmd.com/read/28418274/the-gulf-long-term-follow-up-study-gulf-study-biospecimen-collection-at-enrollment
#11
Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Matthew D Curry, John A McGrath, Dale P Sandler, Polly Armsby, Susan Baker, Richard D Cohn, Edward E Gaunt, Audra Hodges, David Johndrow, Steven K Ramsey, Mark Stenzel, Patricia Stewart
The 2010 Deepwater Horizon (DWH) explosion in the Gulf of Mexico led to the largest ever marine oil spill by volume. The GuLF STUDY is investigating possible adverse human health effects associated with oil spill activities. One objective of the study was to utilize biological specimens from study participants to examine spill-related adverse health effects. This study describes the methods for collecting, processing, shipping, and storing specimens during the enrollment phase of the study. GuLF STUDY participants living in Gulf States (Alabama, Florida, Louisiana, Mississippi, and eastern Texas) were eligible to complete a home visit at enrollment, one to three years after the DWH explosion...
April 18, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28417874/effectiveness-of-minimed-640g-with-smartguard%C3%A2-system-for-prevention-of-hypoglycemia-in-pediatric-patients-with-type-1-diabetes-mellitus
#12
Beatriz Villafuerte Quispe, María Martín Frías, M Belén Roldán Martín, Rosa Yelmo Valverde, M Ángeles Álvarez Gómez, Raquel Barrio Castellanos
INTRODUCTION/AIMS: Treatment with the MiniMed 640G-SmartGuard(®) system (640G-SG, sensor-augmented insulin pump system with low predicted glucose suspension feature) has been shown to decrease risk of hypoglycemia without altering metabolic control in patients with T1DM. The study purpose was to assess the impact of 640G-SG on hipoglycemia frequency and on metabolic control in a pediatric population with T1DM. PATIENTS/METHODS: A retrospective study on 21 children treated with 640G-SG...
April 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28416405/development-validation-and-assessment-of-an-ischemic-stroke-or-transient-ischemic-attack-specific-prediction-tool-for-obstructive-sleep-apnea
#13
Jason J Sico, H Klar Yaggi, Susan Ofner, John Concato, Charles Austin, Jared Ferguson, Li Qin, Lauren Tobias, Stanley Taylor, Carlos A Vaz Fragoso, Vincent McLain, Linda S Williams, Dawn M Bravata
BACKGROUND: Screening instruments for obstructive sleep apnea (OSA), as used routinely to guide clinicians regarding patient referral for polysomnography (PSG), rely heavily on symptomatology. We sought to develop and validate a cerebrovascular disease-specific OSA prediction model less reliant on symptomatology, and to compare its performance with commonly used screening instruments within a population with ischemic stroke or transient ischemic attack (TIA). METHODS: Using data on demographic factors, anthropometric measurements, medical history, stroke severity, sleep questionnaires, and PSG from 2 independently derived, multisite, randomized trials that enrolled patients with stroke or TIA, we developed and validated a model to predict the presence of OSA (i...
April 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28414673/purulent-pericarditis-due-to-an-infected-pacemaker-lead
#14
Teresa Backes
INTRODUCTION: Intravenous drug users have a substantially increased risk of infective endocarditis, especially in the setting of implanted cardiac devices. Purulent pericarditis is a rare occurrence that can occur iatrogenically or through direct or hematogenous spread. CASE DESCRIPTION: A 75 year old man with a past medical history significant for hepatitis C, IV drug abuse, and sick sinus syndrome status post pacemaker was brought in by EMS with a chief complaint of diaphoresis and chest pain...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413425/association-of-retinol-binding-protein-4-with-metabolic-syndrome-in-first-degree-relatives-of-type-2-diabetic-patients
#15
Marjan Tabesh, Atsa Noroozi, Masood Amini, Awat Feizi, Sahar Saraf-Bank, Maryam Zare
BACKGROUND: Retinol-binding protein 4 (RBP4) is known to regulate lipid and glucose metabolism and insulin resistance. The influences of RBP4 on metabolic syndrome (MS) are still unclear. The purpose of this study is to evaluate the association between serum levels of RBP4 and MS components in first-degree relations of type 2 diabetic patients. MATERIALS AND METHODS: This cross-sectional study was performed within the framework of the diabetes prevention project in Isfahan...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28412276/the-influence-of-hypertension-on-daytime-sleepiness-in-obstructive-sleep-apnea
#16
Helena Martynowicz, Robert Skomro, Paweł Gać, Grzegorz Mazur, Irena Porębska, Agnieszka Bryłka, Wojciech Nowak, Michał Zieliński, Anna Wojakowska, Rafał Poręba
Daytime sleepiness is a common symptom among hypertensive patients. The aim of this study was to determine subjective sleepiness assessed by Epworth Sleepiness Scale (ESS) and to asses sleep architecture in 304 patients with arterial hypertension. All patients underwent a standardized diagnostic overnight, polysomnography. The control group consisted of 67 normotensives. The hypertensive patients had a decreased sleep efficiency, mean and minimum oxygen saturation levels, and increased apnea/hypopnea index and oxygen desaturation index compared with normotensive patients...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28411070/development-and-initial-testing-of-the-flow-instrument-a-novel-assessment-of-lower-urinary-tract-symptoms-in-men
#17
Kelvin A Moses, Daniel Heslop, Derek M Griffith, Arturo Holmes, Lisa Sherden, Consuelo H Wilkins, Kenneth A Wallston
PURPOSE: To develop a method of assessing lower urinary tract symptoms (LUTS) regardless of literacy/numeracy. MATERIALS AND METHODS: We convened focus groups and developed a questionnaire based on four identified domains of urinary function: Frequency, Incontinence (Leakage), Nocturia (Overnight voiding), and Weak stream (FLOW). We pilot tested the novel questionnaire in 64 men and performed quantitative analysis to determine internal consistency. Criterion validity was established via direct comparison to the American Urological Association Symptom Score (AUA-SS) in a larger cohort of 161 men...
April 11, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28410600/primary-adrenal-non-hodgkin-lymphoma-a-case-report-and-review-of-the-literature
#18
Nanik Ram, Owais Rashid, Saad Farooq, Imran Ulhaq, Najmul Islam
BACKGROUND: Lymphomas are cancers that arise from the white blood cells and have been traditionally divided into two large subtypes: Hodgkin and non-Hodgkin lymphoma. B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma; almost 85% of patients with lymphoma have this variant. Lymphomas can potentially arise from any lymphoid tissue located in the body; however, primary adrenal non-Hodgkin lymphoma is extremely rare. We report the history, examination findings, and laboratory results of a 50-year-old man diagnosed with a primary left adrenal diffuse large B-cell lymphoma...
April 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28410281/evaluated-conjunctival-blood-flow-velocity-in-daily-contact-lens-wearers
#19
Yingying Shi, Liang Hu, Wan Chen, Dongyi Qu, Hong Jiang, Jianhua Wang
OBJECTIVE: This study examined conjunctival microvasculature development in long-term habitual contact lens (HCL) wearers after a night of sleep. METHODS: Twenty HCL wearers (15 women and 5 men, aged 28.6±6.9 years, mean age±standard deviation) who had worn contact lenses on a daily basis for at least 3 years and 40 noncontact lens (NCL) wearers (23 women and 17 men, aged 36.5±6.6 years, mean age±standard deviation) participated in the study. A functional slitlamp biomicroscopy imaging system was used to image the temporal bulbar conjunctiva...
April 13, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28410280/long-term-impacts-of-orthokeratology-treatment-on-sub-basal-nerve-plexus-and-corneal-sensitivity-responses-and-their-reversibility
#20
María Nombela-Palomo, Gema Felipe-Marquez, Miguel Angel Teus, Jose Luis Hernandez-Verdejo, Amelia Nieto-Bona
PURPOSE: To examine the effects of one year of overnight orthokeratology (OK) treatment on the sub-basal nerve plexus (SBNP) and corneal sensitivity and to assess the reversibility of these effects one month after treatment interruption. METHODS: Thirty-two subjects with low-moderate myopia underwent OK treatment for one year. Fifteen non-contact lens wearers served as controls. At the time points baseline, one year of treatment, and one month after removing the OK lenses, two tests were conducted: corneal sensitivity (Cochet-Bonnet esthesiometer) and SBNP imaging by in vivo confocal microscopy...
April 13, 2017: Eye & Contact Lens
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