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https://www.readbyqxmd.com/read/29781595/-results-of-the-implementation-of-an-antimicrobial-stewardship-program-in-the-gerencia-de-atenci%C3%A3-n-integrada-of-alcazar-de-san-juan-castilla-la-mancha
#1
M A Asencio Egea, O Herráez Carrera, M Huertas Vaquero, H D Patiño Ortega, M Franco Huerta, P Alcázar Carmona, M C Conde García, C Muñoz-Cuevas, C Román Ortiz, J Gaitán Pitera, R Carranza González, J R Barberá
OBJECTIVE: Our aim was to evaluate the efficiency of an ASP after its implementation in 2016 in a Spanish hospital quality system. METHODS: Efficiency of the ASP was measured by process and outcome indicators at the level of the patient's quality of life, antimicrobial consumption and percentage of resistance to them during the 2016-2017 period. In 2017, the failures mode and effects analysis (FMEA) methodology was applied. An annual satisfaction survey was conducted...
May 18, 2018: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/29774893/prevalence-and-antimicrobial-sensitivity-pattern-of-urinary-tract-infection-among-children-with-cerebral-palsy-moshi-tanzania
#2
Amon Ryakitimbo, Rune Philemon, Festo Mazuguni, Levina Msuya
Background: Urinary tract infection (UTI) in children with cerebral palsy (CP) is a challenging yet common clinical condition. Children with CP bare the greatest risk of contracting UTI because of their difficulties in neuromotor control which lead to delay of bladder control, causing incomplete bladder emptying and urine retention. Method: This was an analytical cross-sectional study that was conducted from September 2016 to March 2017 at Comprehensive Community Based Rehabilitation in Tanzania - Moshi and Kilimanjaro Christian Medical Centre Neurological Pediatrics Outpatient Clinic...
2018: Pediatric Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29754478/methicillin-resistant-staphylococcus-aureus-contamination-of-phlebotomy-tourniquets-and-faucets
#3
T Abeywickrama, K Amarasinghe, S Wijerathne, C Dharmaratne, D Fernando, B C Senaratna, H A K M Gunasekera
Introduction: Methicillin resistant Staphylococcus aureus (MRSA) is transmitted through direct contact or fomites. The most important means of nosocomial spread is by hospital personnel. However, fomites are being increasingly recognized as sources of nosocomial infection. Objectives: Our aim was to describe the MRSA contamination rate of phlebotomy tourniquets and faucets in a tertiary care hospital and to compare the contamination of plastic tourniquets with that of fabric tourniquets...
March 31, 2018: Ceylon Medical Journal
https://www.readbyqxmd.com/read/29746358/delayed-cerebral-injury-in-adults-with-bacterial-meningitis-a-novel-complication-of-adjunctive-steroids
#4
Cinthia Gallegos, Farrell Tobowlosky, Masayuki Nigo, Rodrigo Hasbun
OBJECTIVES: To report the prevalence of delayed cerebral injury in adults with bacterial meningitis and explore its association with adjunctive steroids. DESIGN: Retrospective analysis of adults with bacterial meningitis between 2005 and 2016. SETTING: Ten hospitals in the Greater Houston area. PATIENTS: Consecutive subjects with culture proven community-acquired bacterial meningitis. INTERVENTION: Subjects were categorized as receiving or not adjunctive steroids within 4 hours...
May 9, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29728757/recurrent-meningitis-in-children-etiologies-outcome-and-lessons-to-learn
#5
Amira Masri, Abeer Alassaf, Najwa Khuri-Bulos, Imad Zaq, Azmy Hadidy, Faris G Bakri
PURPOSE: Recurrent meningitis in children is a rare condition. However, its early recognition is important in order to prevent serious complications. This study aims to review cases of recurrent meningitis in children. METHODS: This is a retrospective study that included children diagnosed with recurrent meningitis and who were followed at child neurology clinic at the Jordan University Hospital from January 2001 to June 2017. RESULTS: Thirteen patients were included (nine males and four females)...
May 4, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29670792/pyogenic-spondylitis-caused-by-methicillin-resistant-staphylococcus-aureus-associated-with-tracheostomy-followed-by-resection-of-ossification-of-the-anterior-longitudinal-ligament
#6
Michio Hongo, Naohisa Miyakoshi, Masashi Fujii, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Yoichi Shimada
Symptomatic ossification of the anterior longitudinal ligament (OALL) is rare. However, when the osteophyte enlarges and obstructive symptoms occur, the patient may require surgery. We present a case of pyogenic spondylitis caused by methicillin-resistant Staphylococcus aureus associated with tracheostomy followed by resection of OALL. A 69-year-old woman with OALL complained of dysphagia and suffocation, which was caused by prominent OALL at C4-5. Tracheostomy was performed, followed by osteophytectomy 6 weeks later...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29563378/infective-endocarditis-associated-with-atopic-dermatitis
#7
Shigeaki Aoyagi, Takeshi Oda, Kumiko Wada, Eiji Nakamura, Tomokazu Kosuga, Hiroshi Yasunaga
We report a case of aortic valve infective endocarditis (IE) in a 24-year-old man with atopic dermatitis (AD). He had a history of balloon valvuloplasty for a stenotic bicuspid aortic valve, and had dental caries but no invasive dental procedure before the onset of IE. On admission, skin lesions of AD with itching and scratches were found on the neck, trunk, and extremities. Echocardiography showed a vegetation on the aortic valve with mild steno-regurgitation, but extension of IE to the annulus was not detected...
March 30, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29562861/brain-abscess-after-stent-assisted-coiling-for-ruptured-middle-cerebral-artery-aneurysm
#8
Jung Ho Ko, Young-Joon Kim, Hyun Ho Jung
A 24-year-old man was admitted with sudden severe headache. Brain computed tomography (CT) revealed a subarachnoid hemorrhage in the basal cistern and both Sylvian cisterns and a left internal carotid artery angiogram showed a small aneurysm on the bifurcation of the left middle cerebral artery. We performed Y-configured stent-assisted coil embolization. On the fifth post-embolization day, the patient had chills, and his body temperature was over 38℃. Staphylococcus aureus was cultured from the venous blood sample...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29549386/ion-channels-induced-by-antimicrobial-agents-in-model-lipid-membranes-are-modulated-by-plant-polyphenols-through-surrounding-lipid-media
#9
Svetlana S Efimova, Anastasiia A Zakharova, Roman Ya Medvedev, Olga S Ostroumova
The potential therapeutic applications of plant polyphenols in various neurological, cardiovascular, metabolic and malignant disorders determine the relevance of studying the molecular mechanisms of their action on the cell membranes. Here, the quantitative changes in the physical parameters of model bilayer lipid membranes upon the adsorption of plant polyphenols were evaluated. It was shown that butein and naringenin significantly decreased the intrinsic dipole potential of cholesterol-free and cholesterol-enriched membranes...
March 16, 2018: Journal of Membrane Biology
https://www.readbyqxmd.com/read/29483776/chronic-dialysis-patients-with-infectious-spondylodiscitis-have-poorer-outcomes-than-non-dialysis-populations
#10
George Kuo, Wei-Chiao Sun, Yueh-An Lu, Chao-Yu Chen, Huang-Kai Kao, Yu Lin, Yung-Chang Chen, Cheng-Chieh Hung, Ya-Chung Tian, Hsiang-Hao Hsu
Purpose: Infectious spondylodiscitis is a serious disease that can lead to permanent neurological deficit. Because there were only a few case reports or series featuring infectious spondylodiscitis in chronic dialysis patients, we investigated the epidemiology and outcome in the chronic dialysis patients versus general population. Materials and methods: We retrospectively identified chronic dialysis patients admitted for infectious spondylodiscitis between January 2002 and December 2015...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29354239/comparative-analysis-of-spontaneous-infectious-spondylitis-pyogenic-versus-tuberculous
#11
Yangwon Lee, Bum-Joon Kim, Se-Hoon Kim, Seung-Hwan Lee, Won-Hyung Kim, Sung-Won Jin
Objective: Spondylitis is often chemotherapy resistant and requires long-term treatment. Without adequate chemotherapy, the outcome can be fatal or result in severe neurologic damage. Therefore, differentiating the etiology of spondylitis is very important, particularly in spontaneous cases. As the prevalence of tuberculosis in Korea has decreased in recent years, updated clinical research about spondylitis is warranted. Methods: From April 2010 to March 2016, data from spondylitis patients were collected retrospectively...
January 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29321098/spondylodiscitis-diagnosis-and-treatment-options
#12
Christian Herren, Norma Jung, Miguel Pishnamaz, Marianne Breuninger, Jan Siewe, Rolf Sobottke
BACKGROUND: A recent population-based study from Denmark showed that the incidence of spondylodiscitis rose from 2.2 to 5.8 per 100 000 persons per year over the period 1995-2008; the age-standardized incidence in Germany has been estimated at 30 per 250 000 per year on the basis of data from the Federal Statistical Office (2015). The early diagnosis and treatment of this condition are essential to give the patient the best chance of a good outcome, but these are often delayed because it tends to present with nonspecific manifestations, and fever is often absent...
December 25, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29206837/pyogenic-vertebral-osteomyelitis-of-the-elderly-characteristics-and-outcomes
#13
Johan Courjon, Adrien Lemaignen, Idir Ghout, Audrey Therby, Nadia Belmatoug, Aurélien Dinh, Guillaume Gras, Louis Bernard
BACKGROUND: The incidence of pyogenic vertebral osteomyelitis (PVO) has increased over the past two decades. One possible cause of this increase is the aging of the population, which results in more comorbidities in high income countries. OBJECTIVE: To better characterize the clinical presentation and outcome of PVO in the elderly. DESIGN: We conducted a post-hoc analysis of a previously published trial that studied treatment duration in PVO and compared the presentation and outcomes according to age...
2017: PloS One
https://www.readbyqxmd.com/read/29123892/a-case-of-panspinal-epidural-abscess-that-presented-with-meningeal-irritation
#14
Naoki Okada, Takashi Nishiyama, Maki Kurihara, Yusuke Nishimura, Yoshiro Nishimura, Yukihiro Ando, Saori Otsubo, Katsumi Yamada, Yuji Maeda
Case: In rare cases, spinal epidural abscess involves the entire spine and can lead to neurological deficits and sepsis if treatment is delayed or suboptimal. A 65-year-old man was admitted with a diagnosis of bacterial meningitis. After admission, magnetic resonance imaging showed a spinal epidural abscess from the cervical to lumbar spine. Blood culture revealed Staphylococcus aureus . The patient was initially treated medically because he had no neurological deficits. Repeat blood culture remained positive and abscesses were found in the mediastinum and bilateral psoas muscles...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29055524/-role-of-surgery-in-spontaneous-spondylodiscitis-experience-in-83-consecutive-patients
#15
Javier Martín-Alonso, Pedro David Delgado-López, José Manuel Castilla-Díez, Vicente Martín-Velasco, Ana María Galacho-Harriero, Sara Ortega-Cubero, Elena Araus-Galdós, Antonio Rodríguez-Salazar
OBJECTIVE: To describe and discuss the role of surgery in the management of spontaneous spondylodiscitis. PATIENTS AND METHODS: Retrospective review on the outcome and complications of a cohort of patients undergoing surgery for spontaneous (non-postoperative) spondylodiscitis of any spinal level or aetiology. RESULTS: From 1995 to 2014, 83 patients (45% females, median age 66) with spondylodiscitis were treated. Microbiological confirmation was obtained in 67...
March 2018: Neurocirugía
https://www.readbyqxmd.com/read/28991051/association-between-cardiac-surgery-and-mortality-among-patients-with-infective-endocarditis-complicated-by-sepsis-and-septic-shock
#16
Vladimir Krajinovic, Stipe Ivancic, Petar Gezman, Bruno Barsic
BACKGROUND: Sepsis and septic shock are common presentations of infective endocarditis (IE), but little is known about clinical characteristics in this group of patients, use of surgical treatment, and their associations with outcome. We sought to determine the influence of cardiac surgery (CS) on the outcome of patients with IE in different stages of sepsis severity. METHODS: Two hundred ninety four patients with definite IE native or prosthetic valve IE admitted between 2000 and 2011...
October 4, 2017: Shock
https://www.readbyqxmd.com/read/28951964/ct-guided-minimally-invasive-treatment-for-an-extensive-spinal-epidural-abscess-a-case-report-and-literature-review
#17
Bing Ran, XinRong Chen, Qiong Zhong, Min Fu, Jun Wei
PURPOSE: We present a case involving an extensive epidural abscess that was successfully treated with computed tomography (CT)-guided percutaneous needle drainage and systemic antibiotic therapy. METHODS: A 44-year-old woman with a history of spine injection procedures complained of severe backache and progressive radiating pain in her right lower extremity followed by sensory deficits in her right lower limb. A laboratory examination revealed leukocytosis and hyperglycemia...
September 22, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28884664/early-nasopharyngeal-microbial-signature-associated-with-severe-influenza-in-children-a-retrospective-pilot-study
#18
Stanley Langevin, Maxime Pichon, Elise Smith, Juliet Morrison, Zachary Bent, Richard Green, Kristi Baker, Owen Solberg, Yves Gillet, Etienne Javouhey, Bruno Lina, Michael G Katze, Laurence Josset
A few studies have highlighted the importance of the respiratory microbiome in modulating the frequency and outcome of viral respiratory infections. However, there are insufficient data on the use of microbial signatures as prognostic biomarkers to predict respiratory disease outcomes. In this study, we aimed to evaluate whether specific bacterial community compositions in the nasopharynx of children at the time of hospitalization are associated with different influenza clinical outcomes. We utilized retrospective nasopharyngeal (NP) samples (n=36) collected at the time of hospital arrival from children who were infected with influenza virus and had been symptomatic for less than 2 days...
September 8, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28868201/never-say-never-again-a-bone-graft-infection-due-to-a-hornet-sting-thirty-nine-years-after-cranioplasty
#19
Rosario Maugeri, Roberto G Giammalva, Francesca Graziano, Luigi Basile, Carlo Gulì, Antonella Giugno, Domenico G Iacopino
BACKGROUND: Cranioplasty (CP) is a widespread surgical procedure aimed to restore skull integrity and physiological cerebral hemodynamics, to improve neurological functions and to protect the underlying brain after a life-saving decompressive craniectomy (DC). Nevertheless, CP is still burdened by surgical complications, among which early or late graft infections are the most common outcome-threatening ones. CASE DESCRIPTION: We report the case of 48-year-old man admitted to our neurosurgical unit because of a painful right frontal swelling and 1-week purulent discharge from a cutaneous fistula...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28733571/a-rare-case-of-methicillin-resistant-staphylococcus-aureus-mrsa-cerebral-abscess-secondary-to-conjunctivitis
#20
Y K Gan, A Z Azmi, S A Ghani, A Samsudin
This case report discusses the rare association of cerebral abscess related to conjunctivitis in an otherwise healthy child. A 6 year old boy presented with conjunctivitis was treated with topical antibiotics and resolved after a week. Conjunctival swab cultures grew MRSA. A month later he developed status epileptics and CT scans revealed a large cerebral abscess. He was treated with intravenous antibiotics which covered for MRSA, along with an incision and drainage for the cerebral abscess. Pus cultures grew MRSA...
June 2017: Medical Journal of Malaysia
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