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neurologic aureus

George Kuo, Wei-Chiao Sun, Yueh-An Lu, Chao-Yu Chen, Huang-Kai Kao, Yu Lin, Yung-Chang Chen, Cheng-Chieh Hung, Ya-Chung Tian, Hsiang-Hao Hsu
Purpose: Infectious spondylodiscitis is a serious disease that can lead to permanent neurological deficit. Because there were only a few case reports or series featuring infectious spondylodiscitis in chronic dialysis patients, we investigated the epidemiology and outcome in the chronic dialysis patients versus general population. Materials and methods: We retrospectively identified chronic dialysis patients admitted for infectious spondylodiscitis between January 2002 and December 2015...
2018: Therapeutics and Clinical Risk Management
Yangwon Lee, Bum-Joon Kim, Se-Hoon Kim, Seung-Hwan Lee, Won-Hyung Kim, Sung-Won Jin
Objective: Spondylitis is often chemotherapy resistant and requires long-term treatment. Without adequate chemotherapy, the outcome can be fatal or result in severe neurologic damage. Therefore, differentiating the etiology of spondylitis is very important, particularly in spontaneous cases. As the prevalence of tuberculosis in Korea has decreased in recent years, updated clinical research about spondylitis is warranted. Methods: From April 2010 to March 2016, data from spondylitis patients were collected retrospectively...
January 2018: Journal of Korean Neurosurgical Society
Christian Herren, Norma Jung, Miguel Pishnamaz, Marianne Breuninger, Jan Siewe, Rolf Sobottke
BACKGROUND: A recent population-based study from Denmark showed that the incidence of spondylodiscitis rose from 2.2 to 5.8 per 100 000 persons per year over the period 1995-2008; the age-standardized incidence in Germany has been estimated at 30 per 250 000 per year on the basis of data from the Federal Statistical Office (2015). The early diagnosis and treatment of this condition are essential to give the patient the best chance of a good outcome, but these are often delayed because it tends to present with nonspecific manifestations, and fever is often absent...
December 25, 2017: Deutsches Ärzteblatt International
Johan Courjon, Adrien Lemaignen, Idir Ghout, Audrey Therby, Nadia Belmatoug, Aurélien Dinh, Guillaume Gras, Louis Bernard
BACKGROUND: The incidence of pyogenic vertebral osteomyelitis (PVO) has increased over the past two decades. One possible cause of this increase is the aging of the population, which results in more comorbidities in high income countries. OBJECTIVE: To better characterize the clinical presentation and outcome of PVO in the elderly. DESIGN: We conducted a post-hoc analysis of a previously published trial that studied treatment duration in PVO and compared the presentation and outcomes according to age...
2017: PloS One
Naoki Okada, Takashi Nishiyama, Maki Kurihara, Yusuke Nishimura, Yoshiro Nishimura, Yukihiro Ando, Saori Otsubo, Katsumi Yamada, Yuji Maeda
Case: In rare cases, spinal epidural abscess involves the entire spine and can lead to neurological deficits and sepsis if treatment is delayed or suboptimal. A 65-year-old man was admitted with a diagnosis of bacterial meningitis. After admission, magnetic resonance imaging showed a spinal epidural abscess from the cervical to lumbar spine. Blood culture revealed Staphylococcus aureus. The patient was initially treated medically because he had no neurological deficits. Repeat blood culture remained positive and abscesses were found in the mediastinum and bilateral psoas muscles...
July 2017: Acute Medicine & Surgery
Javier Martín-Alonso, Pedro David Delgado-López, José Manuel Castilla-Díez, Vicente Martín-Velasco, Ana María Galacho-Harriero, Sara Ortega-Cubero, Elena Araus-Galdós, Antonio Rodríguez-Salazar
OBJECTIVE: To describe and discuss the role of surgery in the management of spontaneous spondylodiscitis. PATIENTS AND METHODS: Retrospective review on the outcome and complications of a cohort of patients undergoing surgery for spontaneous (non-postoperative) spondylodiscitis of any spinal level or aetiology. RESULTS: From 1995 to 2014, 83 patients (45% females, median age 66) with spondylodiscitis were treated. Microbiological confirmation was obtained in 67...
October 18, 2017: Neurocirugía
Vladimir Krajinovic, Stipe Ivancic, Petar Gezman, Bruno Barsic
BACKGROUND: Sepsis and septic shock are common presentations of infective endocarditis (IE), but little is known about clinical characteristics in this group of patients, use of surgical treatment, and their associations with outcome. We sought to determine the influence of cardiac surgery (CS) on the outcome of patients with IE in different stages of sepsis severity. METHODS: Two hundred ninety four patients with definite IE native or prosthetic valve IE admitted between 2000 and 2011...
October 4, 2017: Shock
Bing Ran, XinRong Chen, Qiong Zhong, Min Fu, Jun Wei
PURPOSE: We present a case involving an extensive epidural abscess that was successfully treated with computed tomography (CT)-guided percutaneous needle drainage and systemic antibiotic therapy. METHODS: A 44-year-old woman with a history of spine injection procedures complained of severe backache and progressive radiating pain in her right lower extremity followed by sensory deficits in her right lower limb. A laboratory examination revealed leukocytosis and hyperglycemia...
September 22, 2017: European Spine Journal
Stanley Langevin, Maxime Pichon, Elise Smith, Juliet Morrison, Zachary Bent, Richard Green, Kristi Baker, Owen Solberg, Yves Gillet, Etienne Javouhey, Bruno Lina, Michael G Katze, Laurence Josset
A few studies have highlighted the importance of the respiratory microbiome in modulating the frequency and outcome of viral respiratory infections. However, there are insufficient data on the use of microbial signatures as prognostic biomarkers to predict respiratory disease outcomes. In this study, we aimed to evaluate whether specific bacterial community compositions in the nasopharynx of children at the time of hospitalization are associated with different influenza clinical outcomes. We utilized retrospective nasopharyngeal (NP) samples (n=36) collected at the time of hospital arrival from children who were infected with influenza virus and had been symptomatic for less than 2 days...
September 8, 2017: Journal of General Virology
Rosario Maugeri, Roberto G Giammalva, Francesca Graziano, Luigi Basile, Carlo Gulì, Antonella Giugno, Domenico G Iacopino
BACKGROUND: Cranioplasty (CP) is a widespread surgical procedure aimed to restore skull integrity and physiological cerebral hemodynamics, to improve neurological functions and to protect the underlying brain after a life-saving decompressive craniectomy (DC). Nevertheless, CP is still burdened by surgical complications, among which early or late graft infections are the most common outcome-threatening ones. CASE DESCRIPTION: We report the case of 48-year-old man admitted to our neurosurgical unit because of a painful right frontal swelling and 1-week purulent discharge from a cutaneous fistula...
2017: Surgical Neurology International
Y K Gan, A Z Azmi, S A Ghani, A Samsudin
This case report discusses the rare association of cerebral abscess related to conjunctivitis in an otherwise healthy child. A 6 year old boy presented with conjunctivitis was treated with topical antibiotics and resolved after a week. Conjunctival swab cultures grew MRSA. A month later he developed status epileptics and CT scans revealed a large cerebral abscess. He was treated with intravenous antibiotics which covered for MRSA, along with an incision and drainage for the cerebral abscess. Pus cultures grew MRSA...
June 2017: Medical Journal of Malaysia
Shaoqiang Liu, Qiang Qi, Zhongqiang Chen, Ning Liu, Zhaoqing Guo, Chuiguo Sun, Weishi Li, Yan Zeng, Zhongjun Liu
STUDY DESIGN: A retrospective clinical review. PURPOSE: To investigate the difference in clinical manifestations and severity between polymicrobial and monomicrobial infections after spinal surgery. OVERVIEW OF LITERATURE: Surgical site infections (SSIs) after spinal surgery are a major diagnostic and therapeutic challenge for spinal surgeons. Polymicrobial infections after spinal surgery seem to result in poorer outcomes than monomicrobial infections because of complementary resistance to antibiotics...
June 2017: Asian Spine Journal
Eun Jeong Joo, Doo Ryeon Chung, So Hyun Kim, Jin Yang Baek, Nam Yong Lee, Sun Young Cho, Young Eun Ha, Cheol In Kang, Kyong Ran Peck, Jae Hoon Song
BACKGROUND: As community-genotype methicillin-resistant Staphylococcus aureus (MRSA) strains spread into hospitals, the genotypes of the MRSA strains causing hospital-acquired (HA) infections have become more diverse. We describe clinical characteristics of nosocomial MRSA infections by a community-genotype of sequence type (ST) 72. MATERIALS AND METHODS: A case-control study was designed among patients with HA-MRSA infections. Forty patients with infections caused by ST72-MRSA SCCmec type IV were selected as cases...
June 2017: Infection & Chemotherapy
Stamatis Karakonstantis, Despoina Galani, Sevasti Maragou, Asimina Koulouridi, Dimitra Kalemaki, Charalampos Lydakis
INTRODUCTION: Direct intramedullary infections are considered very rare. Only few reports of Staphylococcus aureus myelitis have been published. CASE PRESENTATION: Our patient, a 79-year-old male, presented with a 2-day history of high-grade fever and high inflammatory markers and progressively developed tetraplegia during hospitalization. Lumbar puncture revealed cerebrospinal fluid pleocytosis and a spinal cord MRI revealed transverse myelitis at the level of C3-C5 and possible osteomyelitis of C5-T1...
2017: Spinal Cord Series and Cases
Adrien Lemaignen, Idir Ghout, Aurélien Dinh, Guillaume Gras, Bruno Fantin, Virginie Zarrouk, Robert Carlier, Jean-Edouard Loret, Eric Denes, Alix Greder, François-Xavier Lescure, David Boutoille, Pierre Tattevin, Bertrand Issartel, Jean-Philippe Cottier, Louis Bernard
Severe neurological deficit (SND) is a rare but major complication of pyogenic vertebral osteomyelitis (PVO). We aimed to determine the risk factors and the variables associated with clinical improvement for SND during PVO.This case-control study included patients without PVO-associated SND enrolled in a prospective randomized antibiotic duration study, and patients with PVO-associated SND managed in 8 French referral centers. Risk factors for SND were determined by logistic regression.Ninety-seven patients with PVO-associated SND cases, and 297 controls were included...
May 2017: Medicine (Baltimore)
Pedro Ayau, Ana C Bardossy, Guillermo Sanchez, Ricardo Ortiz, Daniela Moreno, Pamela Hartman, Khulood Rizvi, Tyler C Prentiss, Mary B Perri, Meredith Mahan, Vanthida Huang, Katherine Reyes, Marcus J Zervos
OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) blood stream infections (BSI) are a major health care problem accounting for a large percentage of nosocomial infections. The aim of this study was to identify risk factors associated with 30-day mortality in patients with MRSA BSI. METHODS: This was a retrospective study performed in Southeast Michigan. Over a 9- year period, a total of 1,168 patients were identified with MRSA BSI. Patient demographics and clinical data were retrieved and evaluated using electronic medical health records...
August 2017: International Journal of Infectious Diseases: IJID
Mauricio Pons, Leila Pérez, Facundo Juárez
Spinal epidural abscess is an uncommon pathology. It has an incidence of one case per 100 000 individuals. An increase is observed due to the raise of risk factors such as diabetes mellitus, spinal abnormalities, tattoos, acupuncture, epidural analgesia, and a greater availability of imaging methods. It is a purulent collection located between the dura and the medullary canal. The most common germs are Staphylococcus aureus and Gram-negative bacteria. Without timely treatment, it evolves to medullary compression and permanent neurological sequelae...
June 1, 2017: Archivos Argentinos de Pediatría
Geeta Nagpal, John P Flaherty, Honorio T Benzon
OBJECTIVE: Sacroiliac joint injections are frequently performed procedures in the management of acute and chronic low-back pain, including patients with various immunocompromised states. Infectious complications following these procedures along with other spinal injections are rarely reported, but the true incidence is unknown. The purpose of this report is to highlight the devastating neurologic sequela that can occur, and to discuss potential future management strategies. CASE REPORT: We present a patient who developed diskitis, osteomyelitis, spinal epidural abscess, meningitis, and endocarditis from Staphylococcus aureus, all of which developed shortly after a sacroiliac joint injection...
July 2017: Regional Anesthesia and Pain Medicine
Joo Seop Kim, Min-Kyung Kang, A Jin Cho, Yu Bin Seo, Kun Il Kim
BACKGROUND: Infective endocarditis is associated with not only cardiac complications but also neurologic, renal, musculoskeletal, and systemic complications related to the infection, such as embolization, metastatic infection, and mycotic aneurysm. CASE PRESENTATION: We report three cases (the first patient is Chinese and the other two are Koreans) of complicated infective endocarditis; two of the cases were associated with a mycotic aneurysm, and one case was associated with a splenic abscess...
May 8, 2017: Journal of Medical Case Reports
Mackenzie Gabler
Purulent pericarditis is a rare but devastating disease process and even when treated, carries a poor prognosis. Cardiac tamponade is the most severe complication of purulent pericarditis and without acute surgical intervention, is often fatal. Diagnosis requires pericardiocentesis; however, early consideration of the disease and its complications in the emergency department (ED) can be life-saving. Here, we present a case of an intravenous drug user who presented with altered mental status and a rectal temperature of 105...
August 2017: American Journal of Emergency Medicine
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