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https://www.readbyqxmd.com/read/27688864/development-of-epidural-and-paraspinal-abscesses-after-insufficient-evaluation-and-treatment-of-acute-pyelonephritis-caused-by-staphylococcus-aureus
#1
Mi Jeoung Kim, Hyang Mo Koo, Woo Joo Lee, Jin Hwan Choi, Mi Nyong Choi, Sang Young Park, Woo Jung Kim, Seung Yeon Son
Diagnoses of pyelonephritis caused by Staphylococcus aureus should be accompanied by investigations of concomitant bladder obstruction and metastatic infections, especially to the spine or heart. Complicated pyelonephritis due to S. aureus requires more than 2 weeks of antibiotics, which is the typically recommended treatment duration for pyelonephritis. We describe a patient who was diagnosed with complicated epidural and paraspinal abscesses after insufficient evaluation and treatment of acute pyelonephritis due to S...
September 2016: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/27649016/-surgical-treated-spondylodiscitis-epidemiological-study
#2
Joaquim Soares do Brito, António Tirado, Pedro Fernandes
INTRODUCTION: The term spondylodiscitis aims to describe any spinal infection. Medical treatment is the gold standard; nevertheless, surgical treatment can be indicated. The aim of this work was to study the epidemiological profile in a group of patients with spondylodiscitis surgically treated in the same medical institution between 1997 and 2013. MATERIAL AND METHODS: Eighty five patients with spondylodiscitis were surgically treated in this period. The authors analysed clinical data and image studies for each patient...
May 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27598716/staphylococcus-aureus-mediated-blood-brain-barrier-injury-an-in-vitro-human-brain-microvascular-endothelial-cell-model
#3
Alisha McLoughlin, Keith D Rochfort, Cormac J McDonnell, Steven W Kerrigan, Philip M Cummins
Blood-brain barrier (BBB) disruption constitutes a hallmark event during pathogen-mediated neurological disorders such as bacterial meningitis. As a prevalent opportunistic pathogen, Staphylococcus aureus (SA) is of particular interest in this context, although our fundamental understanding of how SA disrupts the BBB is very limited. This paper employs in vitro infection models to address this. Human brain microvascular endothelial cells (HBMvECs) were infected with formaldehyde-fixed (multiplicity of infection [MOI] 0-250, 0-48 hr) and live (MOI 0-100, 0-3 hr) SA cultures...
September 6, 2016: Cellular Microbiology
https://www.readbyqxmd.com/read/27512508/a-10-year-retrospective-review-of-pediatric-lung-abscesses-from-a-single-center
#4
Kavi Madhani, Eric McGrath, Lokesh Guglani
INTRODUCTION: Pediatric lung abscesses can be primary or secondary, and there is limited data regarding response to treatments and patient outcomes. OBJECTIVES: To assess the clinical and microbiologic profile of pediatric patients with lung abscess and assess the differences in outcomes for patients treated with medical therapy or medical plus surgical therapy. METHODS: A retrospective review of all pediatric patients ≤ 18 years of age that were treated as an inpatient for lung abscess between the dates of August 2004 and August 2014 was conducted...
July 2016: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/27506395/pneumonia-presenting-with-organ-dysfunctions-causative-microorganisms-host-factors-and-outcome
#5
Rosario Menéndez, Beatriz Montull, Soledad Reyes, Isabel Amara-Elori, Rafael Zalacain, Alberto Capelastegui, Javier Aspa, Luis Borderías, Juan J Martín-Villasclaras, Salvador Bello, Inmaculada Alfageme, Felipe Rodríguez de Castro, Jordi Rello, Luis Molinos, Juan Ruiz-Manzano, Antoni Torres
Community-acquired pneumonia (CAP) is a serious infection that may occasionally rapidly evolve provoking organ dysfunctions. We aimed to characterize CAP presenting with organ dysfunctions at the emergency room, with regard to host factors and causative microorganisms, and its impact on 30-day mortality. 460 of 4070 (11.3%) CAP patients had ≥2 dysfunctions at diagnosis, with a 30-day mortality of 12.4% vs. 3.4% in those with one or no dysfunctions. Among them, the most frequent causative microorganisms were Streptococcus pneumoniae, gram-negatives and polymicrobial etiology...
August 6, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27480551/-risk-factors-and-prognosis-of-neurological-complications-in-patients-with-infective-endocarditis
#6
H Wang, L L Guo, L G Fang, L Y Cui, Q Miao, T S Li, W L Zhu, Q Fang
OBJECTIVE: To identify risk factors of neurological complications (NC) in left-sided infective endocarditis (IE) and to assess its impact on the outcome and cardiac surgery. METHODS: Clinical data, NC, treatment and outcome of patients with definite left-sided IE admitted to our hospital during 2001-2012 were retrospectively analyzed. RESULTS: A total of 308 patients with age of (45.3±15.9) years were enrolled. Among them, 65 (21.1%) experienced at least one NC...
August 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/27424376/methicillin-resistant-staphyloccocus-aureus-intracranial-epidural-abscess-with-osteomyelitis-during-pregnancy-a-case-report
#7
Vaya W Tanamai, Brandon-Luke L Seagle, Guoyang Luo
BACKGROUND: The incidence of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection is increasing, and 0.5-4% of pregnant women are colonized. CASE: A 30-year-old pregnant woman at term presented with intractable headache 1 week after incision and drainage of a MRSA-positive axillary abscess. Imaging demonstrated a right-sided epidural abscess with midline shift and myositis of the overlying temporalis muscle. She underwent cesarean delivery followed by craniectomy of osteomyelitic bone and evacuation of the epidural abscess...
May 2016: Journal of Reproductive Medicine
https://www.readbyqxmd.com/read/27417291/age-related-risk-factors-for-bacterial-aetiology-in-community-acquired-pneumonia
#8
José M Sahuquillo-Arce, Rosario Menéndez, Raúl Méndez, Isabel Amara-Elori, Rafael Zalacain, Alberto Capelastegui, Javier Aspa, Luis Borderías, Juan J Martín-Villasclaras, Salvador Bello, Inmaculada Alfageme, Felipe Rodriguez de Castro, Jordi Rello, Luis Molinos, Juan Ruiz-Manzano, Antoni Torres
BACKGROUND AND OBJECTIVE: The objective of this study was to evaluate the effect of age and comorbidities, smoking and alcohol use on microorganisms in patients with community-acquired pneumonia (CAP). METHODS: A prospective multicentre study was performed with 4304 patients. We compared microbiological results, bacterial aetiology, smoking, alcohol abuse and comorbidities in three age groups: young adults (<45 years), adults (45-64 years) and seniors (>65 years)...
July 14, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27383494/analysis-on-the-infections-change-and-measures-for-the-multiple-drug-resistant-bacteria-of-neurology
#9
Wenju Zang
To analyze the bacterial infection situations and the separation situations of multiple drug-resistant bacteria of the neurology of Zhengzhou People's hospital from Feb. 2012 to Dec. 2014. The patients data of neurology were retrieved by means of the doctor workstation system. The infection sites, the classification and drug-resistant feature of bacteria were classified and summarized in Excel. Finally, Compared with the infection sites, the classification and drug-resistant feature of bacteria at different year...
May 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27342809/comparison-of-prognoses-of-staphylococcus-aureus-left-sided-prosthetic-endocarditis-and-prosthetic-endocarditis-caused-by-other-pathogens
#10
Layal Abdallah, Gilbert Habib, Jean-Paul Remadi, Erwan Salaun, Jean-Paul Casalta, Christophe Tribouilloy
BACKGROUND: Staphylococcus aureus prosthetic valve endocarditis (SAPIE) is a serious disease. AIMS: Our objective was to study the clinical, echocardiographic and prognostic characteristics of left-sided SAPIE, and to compare these characteristics with those of left-sided non-S. aureus prosthetic infective endocarditis (NSAPIE) (i.e. left-sided prosthetic infective endocarditis caused by another germ). METHODS: This was a retrospective analysis of 35 cases of SAPIE among 247 cases of left-sided prosthetic valve endocarditis hospitalized at two university hospitals (Amiens and Marseille, France)...
June 21, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/27333712/vertebral-osteomyelitis-in-adult-patients-characteristics-and-outcome
#11
MULTICENTER STUDY
Matej Mustapić, Klaudija Višković, Igor Borić, Domagoj Marjan, Dijana Zadravec, Josip Begovac
The aim of the study was to assess disease characteristics and outcome in patients with vertebral osteomyelitis (VO). A two medical centre retrospective cohort study was performed by chart review after discharge of 110 patients with confirmed VO treated during a 5-year period. Patients were divided in two groups: patients with uncomplicated VO and patients with complicated VO. All patients underwent clinical and biological examinations and magnetic resonance imaging (MRI) according to the same protocol. Patients with complicated VO were significantly older (p = 0...
March 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/27221307/-spondylodiscitis-in-children-and-adolescents
#12
A Völker, S Schubert, C-E Heyde
BACKGROUND: Spondylodiscitis in children is rare. The condition has an incidence of 2 to 4 % of all infectious skeletal diseases in children. AIM: Aim of the article is the presentation of epidemiology, the clinical signs, radiological findings as well the treatment options of non-specific and specific spondylodiscitis in children. METHODS: The available literature was reviewed. RESULTS: Non-specific spondylodiscitis in children is caused by haematogenous spread of pathogens...
June 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27186578/detection-of-bacteriuria-by-canine-olfaction
#13
Maureen Maurer, Michael McCulloch, Angel M Willey, Wendi Hirsch, Danielle Dewey
Background.  Urinary tract infections (UTIs) are a significant medical problem , particularly for patients with neurological conditions and the elderly. Detection is often difficult in these patients, resulting in delayed diagnoses and more serious infections such as pyelonephritis and life-threatening sepsis. Many patients have a higher risk of UTIs because of impaired bladder function, catheterization, and lack of symptoms. Urinary tract infections are the most common nosocomial infection; however, better strategies are needed to improve early detection of the disease...
March 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27122133/pre-operative-stroke-and-neurological-disability-do-not-independently-affect-short-and-long-term-mortality-in-infective-endocarditis-patients
#14
Mahmoud Diab, Albrecht Guenther, Christoph Sponholz, Thomas Lehmann, Gloria Faerber, Anna Matz, Marcus Franz, Otto W Witte, Mathias W Pletz, Torsten Doenst
BACKGROUND: Infective endocarditis (IE) is still associated with high morbidity and mortality. The impact of pre-operative stroke on mortality and long-term survival is controversial. In addition, data on the severity of neurological disability due to pre-operative stroke are scarce. We analysed the impact of pre-operative stroke and the severity of its related neurological disability on short- and long-term outcome. METHODS: We retrospectively reviewed our data from patients operated for left-sided IE between 01/2007 and 04/2013...
October 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27091490/clinically-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-caused-by-methicillin-sensitive-staphylococcus-aureus-bacteremia-with-toxic-shock-syndrome-a-case-report
#15
Koki Kosami, Tsuneaki Kenzaka, Yuka Sagara, Kensuke Minami, Masami Matsumura
BACKGROUND: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy caused by various pathological processes, but encephalopathy due to bacteria is rare. CASE PRESENTATION: We report the case of a 45-year-old Japanese woman who on receiving chemotherapy for advanced breast cancer developed an altered mental status and dysarthria soon after fever from infection of a subcutaneous implantable port. Staphylococcus aureus was detected in her blood cultures...
April 18, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27074328/brain-abscess-due-to-staphylococcus-aureus-of-cryptogenic-source-in-an-hiv-1-infected-patient-in-use-of-antiretroviral-therapy
#16
Anna Paula Romero de Oliveira, Mara Cristina Pappalardo, Daniel Dantas, Diogo Lins, José Ernesto Vidal
The spectrum of neurological complications associated with human immunodeficiency virus type 1 (HIV-1) infection is broad. The most frequent etiologies include primary diseases (caused by HIV itself) or secondary diseases (opportunistic infections or neoplasms). Despite these conditions, HIV-infected patients are susceptible to other infections observed in patients without HIV infection. Here we report a rare case of a brain abscess caused by Staphylococcus aureus in an HIV-infected patient. After drainage of the abscess and treatment with oxacilin, the patient had a favorable outcome...
2016: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/27070599/infectious-discitis-and-spondylodiscitis-in-children
#17
REVIEW
Nicola Principi, Susanna Esposito
In children, infectious discitis (D) and infectious spondylodiscitis (SD) are rare diseases that can cause significant clinical problems, including spinal deformities and segmental instabilities. Moreover, when the infection spreads into the spinal channel, D and SD can cause devastating neurologic complications. Early diagnosis and treatment may reduce these risks. The main aim of this paper is to discuss recent concepts regarding the epidemiology, microbiology, clinical presentation, diagnosis, and treatment of pediatric D and SD...
2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27025026/-optimization-of-the-treatment-tactics-in-brain-abscess-using-the-puncture-stereotaxic-aspiration
#18
Ya P Zihnkevych, S P Borshchov, K R Kostyuk, T A Malysheva
There was analyzed the application efficacy of stereotaxic aspiration of the brain abscess (BA) content, localized in a deep and functionally significant parts of the brain, in 12 patients--with supratentorial BA. Stereotaxic interventions were performed, using stereotaxic systems CRW Radionics (USA) and the security program for calculation of coordynates StereoFusion, StereoPlan (Radionics), Fraime Link (Medtronic, USA). Postoperative observation period have lasted from 1 to 36 mo, (14 ± 3.6) mo at average...
December 2015: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/26929284/reconstruction-of-vertebral-bone-defects-using-an-expandable-replacement-device-and-bioactive-glass-s53p4-in-the-treatment-of-vertebral-osteomyelitis-three-patients-and-three-pathogens
#19
J Kankare, N C Lindfors
BACKGROUND AND AIMS: Bioactive glass S53P4 is an antibacterial bone substitute with bone-bonding and osteostimulative properties. The bone substitute has been successfully used clinically in spine; trauma; orthopedic; ear, nose, and throat; and cranio-maxillofacial surgeries. Bioactive glass S53P4 significantly reduces the amount of bacteria in vitro and possesses the capacity to kill both planktonic bacteria and bacteria in biofilm. Three patients with severe spondylodiscitis caused by Mycobacterium tuberculosis, Candida tropicalis, or Staphylococcus aureus were operatively treated due to failed conservative treatment...
February 29, 2016: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/26898635/long-term-prognosis-of-left-sided-native-valve-staphylococcus-aureus-endocarditis
#20
Layal Abdallah, Jean-Paul Remadi, Gilbert Habib, Erwan Salaun, Jean-Paul Casalta, Christophe Tribouilloy
BACKGROUND: Staphylococcus aureus infective endocarditis (SAIE) is a serious and common disease. AIMS: To assess the clinical and echocardiographic characteristics and prognostic factors of left-sided native-valve SAIE, and to compare these characteristics between two periods (1990-2000 vs. 2001-2010). METHODS: This was a retrospective analysis of 162 cases of left-sided native-valve SAIE among 1254 patients hospitalized for infective endocarditis (IE) between 1990 and 2010...
April 2016: Archives of Cardiovascular Diseases
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