Luca Diamanti, Alberto Picca, Paola Bini, Matteo Gastaldi, Enrico Alfonsi, Anna Pichiecchio, Eugenia Rota, Roberta Rudà, Francesco Bruno, Veronica Villani, Edvina Galiè, Alberto Vogrig, Mariarosaria Valente, Marco Zoccarato, Valentina Poretto, Bruno Giometto, Carolina Cimminiello, Michele Del Vecchio, Enrico Marchioni
BACKGROUND: Neurological immune-related adverse events (nirAEs) are rare toxicities of immune-checkpoint inhibitors (ICI). With the increase of ICI oncological indications, their incidence is growing. Their recognition and management remain nevertheless challenging. METHODS: A national, web-based database was built to collect cases of neurological symptoms in patients receiving ICI and not attributable to other causes after an adequate workup. RESULTS: We identified 27 patients who developed nirAEs (20 males, median age 69 years)...
March 2022: Neurological Sciences