Martin Gritter, Kuang-Yu Wei, Rosa D Wouda, Usha M Musterd-Bhaggoe, Kyra L Dijkstra, Jesper Kers, Christian Ramakers, Liffert Vogt, Martin H de Borst, Alexander H J Danser, Ewout J Hoorn, Joris I Rotmans
BACKGROUND AND HYPOTHESIS: Dietary potassium (K+) has emerged as a modifiable factor for cardiovascular and kidney health in the general population, but its role in people with chronic kidney disease (CKD) is unclear. Here, we hypothesize that CKD increases the susceptibility to negative effects of low and high K+ diets. METHODS: We compared the effects of low, normal, or high KChloride (KCl) diets and a high KCitrate diet for four weeks in male rats with normal kidney function and in male rats with CKD using the 5/6th nephrectomy model (5/6Nx)...
October 9, 2023: Nephrology, Dialysis, Transplantation