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"muscle injury"

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https://www.readbyqxmd.com/read/29441023/comparison-of-fatty-acid-and-gene-profiles-in-skeletal-muscle-in-normal-and-obese-c57bl-6j-mice-before-and-after-blunt-muscle-injury
#1
Jens-Uwe Werner, Klaus Tödter, Pengfei Xu, Lydia Lockhart, Markus Jähnert, Pascal Gottmann, Annette Schürmann, Ludger Scheja, Martin Wabitsch, Uwe Knippschild
Injury and obesity are two major health burdens affecting millions of people worldwide. Obesity is recognized as a state of chronic inflammation accompanied by various co-morbidities like T2D or cardiovascular diseases. There is increasing evidence that obesity impairs muscle regeneration, which is mainly due to chronic inflammation and to excessive accumulation of lipids in adipose and non-adipose tissue. To compare fatty acid profiles and changes in gene expression at different time points after muscle injury, we used an established drop tower-based model with a defined force input to damage the extensor iliotibialis anticus on the left hind limb of female C57BL/6J mice of normal weight and obese mice...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29432755/pelvic-muscles-mechanical-response-to-strains-in-the-absence-and-presence-of-pregnancy-induced-adaptations-in-a-rat-model
#2
Tatiana Catanzarite, Shannon Bremner, Caitlin L Barlow, Laura Bou-Malham, Shawn O'Connor, Marianna Alperin
BACKGROUND: Maternal birth trauma to the pelvic floor muscles is thought to be consequent to mechanical demands placed on these muscles during fetal delivery that exceed muscle physiological limits. The above is consistent with studies of striated limb muscles that identify hyperelongation of sarcomeres, the functional muscle units, as the primary cause of mechanical muscle injury and resultant muscle dysfunction. However, pelvic floor muscles' mechanical response to strains have not been examined at a tissue level...
February 9, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29423575/normalized-steam-based-diffusion-tensor-imaging-provides-a-robust-assessment-of-muscle-tears-in-football-players-preliminary-results-of-a-new-approach-to-evaluate-muscle-injuries
#3
Chiara Giraudo, Stanislav Motyka, Michael Weber, Manuela Karner, Christoph Resinger, Thorsten Feiweier, Siegfried Trattnig, Wolfgang Bogner
OBJECTIVES: To assess acute muscle tears in professional football players by diffusion tensor imaging (DTI) and evaluate the impact of normalization of data. METHODS: Eight football players with acute lower limb muscle tears were examined. DTI metrics of the injured muscle and corresponding healthy contralateral muscle and of ROIs drawn in muscle tears (ROItear) in the corresponding healthy contralateral muscle (ROIhc_t) in a healthy area ipsilateral to the injury (ROIhi) and in a corresponding contralateral area (ROIhc_i) were compared...
February 8, 2018: European Radiology
https://www.readbyqxmd.com/read/29420397/exercise-induced-abdominal-wall-muscle-injury-resulting-in-rhabdomyolysis-and-mimicking-an-acute-abdomen
#4
Charlene G Echague, John M Csokmay
BACKGROUND: Rhabdomyolysis is characterized by muscle necrosis and release of intracellular constituents, causing muscle pain, weakness, and myoglobinuria. This can be attributed to muscle injury after strenuous exercise. If the abdominal wall is involved, clinical presentation may resemble an acute abdomen. CASE: A 27-year-old woman, gravida 4 para 2, presented with swelling and pain of the mons pubis and abdominal pain after intense powerlifting 2 days prior. A computed tomography scan was performed, revealing abdominal wall inflammation...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29420348/core-muscle-injuries-in-athletes
#5
Alexander E Poor, Johannes B Roedl, Adam C Zoga, William C Meyers
Lower abdominal and groin injuries are among the most common causes of pain and lost playing time in sports. Perhaps the most important obstacle in understanding these injuries is the lack of consensus on nomenclature. There have been numerous advances in recent years in the understanding, prevention, diagnosis, and treatment of these injuries. The purpose of this review is to provide a general perspective on the current understanding of these injuries and a summary of recent advances.
February 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29417778/-unilateral-wiltse-intermuscular-approach-and-contralateral-decompression-for-the-treatment-of-thoracolumbar-burst-fracture
#6
Chi Li, Jing Wang, Hong-Lin Teng, Ming-Yu Zhu, Yang Zhou
OBJECTIVE: To compare the clinical effects and multifidus muscle injury of different approaches, including unilateral Wiltse intermuscular approach and intramuscular approach combined with contralateral decompression, in treating thoracolumbar burst fracture. METHODS: Forty-three patients with thoracolumbar burst fracture were enrolled in the study from January 2010 to December 2014, including 29 males and 14 females with an average age of 42.3 years old(ranged from 21 to 64 years old)...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29407612/alterations-in-haemolymph-proteome-of-mytilus-galloprovincialis-mussel-after-an-induced-injury
#7
Lorena Franco-Martínez, Silvia Martínez-Subiela, Damian Escribano, Sarah Schlosser, Katharina Nöbauer, Ebrahim Razzazi-Fazeli, Diego Romero, Jose Joaquin Cerón, Asta Tvarijonaviciute
A proteomic and biochemical approach was performed to assess the effects of an induced muscle injury on the haemolymph of bivalve molluscs. For this purpose, Mytilus galloprovincialis were exposed to puncture of adductor muscle for three consecutive days, and their haemolymph proteome was then compared to healthy animals using 2-dimensional electrophoresis (2-DE) to identify proteins that differed significantly in abundance. Those proteins were then subjected to tandem mass spectrometry and 6 proteins, namely myosin, tropomyosin, CuZn superoxide dismutase (SOD), triosephosphate isomerase, EP protein and small heat shock protein were identified...
January 30, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29395406/hyperkalemia-in-electrical-burns-a-retrospective-study-in-colombia
#8
Norberto Navarrete
INTRODUCTION: Classically, hyperkalemia has been regarded as a complication in patients with electrical burns. The etiology of hyperkalemia includes metabolic acidosis, destruction of red blood cells, rhabdomyolysis and the development of renal failure. The purpose of this study was to determine the prevalence of hyperkalemia within the first 24h after electrical burn injury and to evaluate the possible association of serum potassium concentration with cutaneous burn size (%TBSA) and serum creatine phosphokinase (CPK) concentration...
January 30, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29394360/the-roles-of-muscle-stem-cells-in-muscle-injury-atrophy-and-hypertrophy
#9
So-Ichiro Fukada
Skeletal muscle is composed of multinuclear cells called myofibers. Muscular dystrophy (a genetic muscle disorder) induces instability in the cell membrane of myofibers and eventually causes myofiber damage. Non-genetic muscle disorders, including sarcopenia, diabetes, bedridden immobility, and cancer cachexia, lead to atrophy of myofibers. In contrast, resistance training induces myofiber hypertrophy. Thus, myofibers exhibit a plasticity that is strongly affected by both intrinsic and extrinsic factors. There is no doubt that muscle stem cells (MuSCs, also known as muscle satellite cells) are indispensable for muscle repair/regeneration, but their contributions to atrophy and hypertrophy are still controversial...
January 31, 2018: Journal of Biochemistry
https://www.readbyqxmd.com/read/29380329/in-vivo-electrical-stimulation-for-the-assessment-of-skeletal-muscle-contractile-function-in-murine-models
#10
Kaio F Vitzel, Marco A Fortes, Gabriel Nasri Marzuca-Nassr, Maria V M Scervino, Carlos H Pinheiro, Leonardo R Silveira, Rui Curi
Skeletal muscle electrical stimulation is commonly used for clinical purposes, assisting recovery, preservation, or even improvement of muscle mass and function in healthy and pathological conditions. Additionally, it is a useful research tool for evaluation of skeletal muscle contractile function. It may be applied in vitro, using cell culture or isolated fibers/muscles, and in vivo, using human subjects or animal models (neuromuscular electrical stimulation - NMES). This chapter focuses on the electrical stimulation of the sciatic nerve as a research method for evaluation of the contractile properties of murine hind limb muscles...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29379910/nanocomposite-injectable-gels-capable-of-self-replenishing-regenerative-extracellular-microenvironments-for-in-vivo-tissue-engineering
#11
Koji Nagahama, Naho Oyama, Kimika Ono, Atsushi Hotta, Keiko Kawauchi, Takahito Nishikata
Injectable hydrogels are biomaterials that have the potential to provide scaffolds to cells for in situ tissue regeneration with a minimally invasive implantation procedure. The success of in vivo tissue engineering utilizing injectable gels depends on providing cells with appropriate scaffolds that present an instructive extracellular microenvironment, which strongly influences the survival, proliferation, organization, and function of cells encapsulated within gels. One of the most important abilities of injectable gels to achieve this function is to adsorb and retain a wide variety of requisite bioactive molecules including nutrients, extracellular matrices, and growth/differentiation factors within gels...
January 30, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29363053/is-platelet-rich-plasma-prp-effective-in-the-treatment-of-acute-muscle-injuries-a-systematic-review-and-meta-analysis
#12
REVIEW
Alberto Grassi, Francesca Napoli, Iacopo Romandini, Kristian Samuelsson, Stefano Zaffagnini, Christian Candrian, Giuseppe Filardo
BACKGROUND: Muscle lesions account for one-third of sport-related injuries, thus representing a substantial problem for both players and their teams. The use of platelet-rich plasma (PRP) injections is rapidly growing in clinical practice, prompted by an unmet clinical need with a large commercial market. However, after early reports of positive preliminary experience, higher quality studies recently questioned the real benefit provided by PRP injections to promote muscle healing and return to sport...
January 23, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29358697/hyperbaric-oxygen-reduces-inflammation-oxygenates-injured-muscle-and-regenerates-skeletal-muscle-via-macrophage-and-satellite-cell-activation
#13
Takuya Oyaizu, Mitsuhiro Enomoto, Naoki Yamamoto, Kunikazu Tsuji, Masaki Horie, Takeshi Muneta, Ichiro Sekiya, Atsushi Okawa, Kazuyoshi Yagishita
Hyperbaric oxygen treatment (HBO) promotes rapid recovery from soft tissue injuries. However, the healing mechanism is unclear. Here we assessed the effects of HBO on contused calf muscles in a rat skeletal muscle injury model. An experimental HBO chamber was developed and rats were treated with 100% oxygen, 2.5 atmospheres absolute for 2 h/day after injury. HBO reduced early lower limb volume and muscle wet weight in contused muscles, and promoted muscle isometric strength 7 days after injury. HBO suppressed the elevation of circulating macrophages in the acute phase and then accelerated macrophage invasion into the contused muscle...
January 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29354938/-effects-of-acupuncture-at-opposite-acupoints-on-expression-of-hepatocyte-growth-factor-in-rats-with-skeletal-muscle-contusion
#14
Anning Zhang, Siqin Huang, Chenglin Tang, Ao Luo, Dandan Zhao, Ruiqi Gao, Chengfang Tan, Huiyu An, Mengjia Wu, Mang Yu
OBJECTIVE: To observe the effects of acupuncture at opposite acupoints on expression of hepatocyte growth factor (HGF) in rats with skeletal muscle contusion, and to explore the mechanism of acupuncture at opposite acupoints on skeletal muscle contusion. METHODS: Fifty-four Sprague Dawley (SD) rats were randomly divided into a blank group (6 rats), a model group (24 rats) and an opposing needling group (24 rats). The model group and opposing needling group were further divided into 1-day subgroup, 3-day subgroup, 5-day subgroup and 7-day subgroup, 6 rats in each one...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29354919/-effects-of-electroacupuncture-at-weizhong-bl-40-on-morphology-and-expression-of-ck-and-il-17-in-rats-with-bupivacaine-induced-multifidus-muscle-injury
#15
Dehui Zou, Yupei Chen, Tong Liu, Zongxiao Lu, Jun Yan, Dongli Chen, Yue Xu, Jiayi Zhang, Yuzhuo Bai, Li Zhang, Zejun Huo
OBJECTIVE: To observe effects of electroacupuncture (EA) at "Weizhong" (BL 40) on morphology and expression of creatine kinase (CK) and interleukin-17 (IL-17) in rats with bupivacaine-induced multifidus muscle injury. METHODS: A total of 32 male SD rats were randomly divided into a control group, a model group, a Weizhong group and a Shenshu group, 8 rats in each one. The rats in the model group, Weizhong group and Shenshu group were treated with intramuscular injection of 0...
September 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29354429/mini-open-incision-sports-hernia-repair-a-surgical-technique-for-core-muscle-injury
#16
Anthony J Scillia, Todd P Pierce, Erica Simone, Richard C Novak, Benton A Emblom
One cause of groin pain in highly active patients may be a core muscle injury, commonly referred to as sports hernia. When patients fail nonoperative management, there are a number of surgical options that may be pursued. Typically, they will involve the direct repair of the rectus abdominis back to the pubis. However, we believe that this repair can be further strengthened by the appropriate lengthening of the adductor longus from the conjoined tendon. Therefore, we present a surgical technique that involves both rectus abdominis repair and adductor longus lengthening in those who show a core muscle injury that is refractory to conservative management...
August 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29343633/hydrogel-biomaterials-and-their-therapeutic-potential-for-muscle-injuries-and-muscular-dystrophies
#17
REVIEW
Rachel Lev, Dror Seliktar
Muscular diseases such as muscular dystrophies and muscle injuries constitute a large group of ailments that manifest as muscle weakness, atrophy or fibrosis. Although cell therapy is a promising treatment option, the delivery and retention of cells in the muscle is difficult and prevents sustained regeneration needed for adequate functional improvements. Various types of biomaterials with different physical and chemical properties have been developed to improve the delivery of cells and/or growth factors for treating muscle injuries...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29340811/a-word-of-caution-never-use-tacks-for-mesh-fixation-to-the-diaphragm
#18
F Köckerling, C Schug-Pass, R Bittner
BACKGROUND: The mesh fixation technique used in repair of hiatal hernias and subxiphoid ventral and incisional hernias must meet strenuous requirements. In the literature, there are reports of life-threatening complications with cardiac tamponade and a high mortality rate on using tacks. The continuing practice of tack deployment for mesh fixation to the diaphragm and esophageal hiatus should be critically reviewed. METHODS: In a systematic search of the available literature in May 2017, 23 cases of severe penetrating cardiac complications were identified...
January 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29337720/update-on-the-role-of-actovegin-in-musculoskeletal-medicine-a-review-of-the-past-10-years
#19
James Brock, David Golding, Paul M Smith, Len Nokes, Alvin Kwan, Paul Y F Lee
BACKGROUND: Actovegin is a biological drug with a controversial history of use in the treatment of sports injuries during the past 60 years. Particular concerns have been raised about its ergogenic potential to enhance performance, but some of these have been based on little more than anecdote. OBJECTIVES: In this article, we review the most recent scientific evidence to determine the clinical efficacy, safety profile, and legal status of Actovegin. METHODS: We considered all studies directly commenting on experience with Actovegin use as the primary intervention within the past 10 years...
January 15, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29332742/the-effects-of-dorso-lumbar-motion-restriction-on-emg-activity-of-selected-muscles-during-running
#20
Joseph J Morley, Edward Traum
The effects of restricting dorso-lumbar spine mobility on electromyographic activity of the erector spinae, quadriceps femoris, hamstrings and gastrocnemius muscles in runners was investigated. Thermoplastic casting material was fashioned into a rigid orthosis and used to restrict spinal motion during running. Volunteers ran on a treadmill at 2.78 m/sec, under normal conditions and with spinal motion restricted. Surface electromyographic data was collected during both sets of trials. Normal electromyographic data was also compared with previous authors to determine similarity with their electromyographic data...
January 2018: Journal of Bodywork and Movement Therapies
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