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https://read.qxmd.com/read/36913419/robotic-radical-cystectomy-with-intracorporeal-urinary-diversion-tips-and-tricks
#1
JOURNAL ARTICLE
Emanuel Darius Cata, Iulia Andras, Andrei Popa, Paul Medan, Teodora Telecan, Razvan Ognean, Lorin Giurgiu, Maximilian Buzoianu, Ioan Coman, Nicolae Crisan
Radical cystectomy represents the standard surgical treatment in case of muscle invasive bladder cancer. During the last two decades a change in the surgical approach of the MIBC has been observed, from open surgery to minimal invasive surgery. Nowadays, in the majority of tertiary urologic centers, robotic radical cystectomy with intracorporeal urinary diversion represents the standard surgical approach. The aim of the current study is to describe in detail the surgical steps of the robotic radical cystectomy and the reconstruction of the urinary diversion and to present our experience...
February 2023: Chirurgia
https://read.qxmd.com/read/35500666/effect-of-glycated-hdl-on-oxidative-stress-and-cholesterol-homeostasis-in-a-human-bladder-cancer-cell-line-j82
#2
JOURNAL ARTICLE
Md ObaidulIslam, Tiziana Bacchetti, Hicham Berrougui, AbdelouahedKhalil, Gianna Ferretti
Epidemiological studies suggest associations between diabetes mellitus (DM) andbladder cancer. Several potential mechanisms may explain the increased bladdercancer burden in DM patients. Hyperglycaemia is associated with dysregulation of cellintracellular metabolism and alterations of lipoprotein metabolism and oxidative stress. Dysfunctional HDL including glycated and oxidized HDL are described in DM. Weevaluated the effect of normal HDL (N-HDL) and glycated HDL (G-HDL) on cellproliferation and oxidative stress of J82 bladder cancer cells...
April 29, 2022: Experimental and Molecular Pathology
https://read.qxmd.com/read/35435161/correlations-between-forkhead-box-d1-expression-and-clinicopathological-characteristics-of-patients-with-bladder-cancer-and-influence-on-biological-behaviors-of-bladder-cancer-cells
#3
JOURNAL ARTICLE
Fuke Wang, Junfeng Yang
OBJECTIVES: To investigate the correlationsbetween forkhead box D1 (FOXD1) expressionand clinicopathological characteristics of bladdercancer and influence on the biological behaviors ofbladder cancer cells. METHODS: The overall survival rate of 87 bladdercancer patients was evaluated to explore the predictivevalue of FOXD1. The expressions of FOXD1 in 87 bladdercancer tissues and 26 adjacent tissues were measuredthrough immunohistochemistry, and the correlationsbetween FOXD1 expression and clinicopathologicalcharacteristics of patients were analyzed...
April 2022: Archivos Españoles de Urología
https://read.qxmd.com/read/33269717/-muscle-invasive-bladder-cancer-and-bladder-preservation-protocols-where-are-we
#4
JOURNAL ARTICLE
José Luis Domínguez Escrig
Radical cystectomy remains as gold standard for treatment of muscle-invasive bladder cancer. Radical cystectomy has a high morbidity and mortalityas sociated even with the new anesthetic and surgical techniques. Some patients are still not candidates for this major surgery. Besides, some patients reject radical cystectomy. Bladder preservation strategies were develop aiming to decrease morbidity and mortality related to major surgery. Bladder preservation allow for improved quality of life and similar oncologic control rates...
December 2020: Archivos Españoles de Urología
https://read.qxmd.com/read/33210440/the-obesity-paradox-defining-the-impact-of-body-mass-index-and-diabetes-mellitus-for-patients-with-non-muscle-invasive-bladder-cancer-treated-with-bacillus-calmette-gu%C3%A3-rin
#5
JOURNAL ARTICLE
Nathan A Brooks, Andrea Kokorovic, Lianchen Xiao, Justin T Matulay, Roger Li, Weranja K B Ranasinghe, Supriya Nagaraju, Yu Shen, Jianjun Gao, Neema Navai, Colin P N Dinney, H Barton Grossman, Ashish M Kamat
OBJECTIVES: To evaluate if the obesity paradox, wherein obesity portends worse overall prognosis for a disease but improved outcomes for patients receiving immunotherapy, exists for patients receiving bacillus Calmette-Guérin (BCG) in a contemporary cohort. PATIENTS AND METHODS: We performed an Institutional Review Board-approved database review to identify patients with non-muscle-invasive bladder cancer (NMIBC) completing at least an induction course of BCG. Clinicopathological variables collected included: body mass index (BMI), medications, and diabetes mellitus (DM)...
July 2021: BJU International
https://read.qxmd.com/read/27432529/association-between-number-of-endoscopic-resections-and-utilization-of-bacillus-calmette-gu%C3%A3-rin-therapy-for-patients-with-high-grade-non-muscle-invasive-bladder-cancer
#6
JOURNAL ARTICLE
Andrew T Lenis, Nicholas M Donin, Mark S Litwin, Christopher S Saigal, Julie Lai, Jan M Hanley, Badrinath R Konety, Karim Chamie
BACKGROUND: Bacillus Calmette-Guérin (BCG) is the reference standard treatment for patients with high-grade, non-muscle-invasive bladder cancer (NMIBC). We previously described noncompliance with guidelines for BCG use in patients with high-risk disease. In the current study, we sought to characterize how the number of endoscopic resections of bladder tumors affects BCG utilization using population-level data. PATIENTS AND METHODS: We queried a Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database to evaluate claims records of 4776 patients diagnosed with high-grade NMIBC between 1992 and 2002 and followed until 2007, who survived for at least 2 years and who did not undergo definitive treatment with cystectomy, radiotherapy, or systemic chemotherapy...
February 2017: Clinical Genitourinary Cancer
https://read.qxmd.com/read/24606737/-inhibitory-effect-of-2-hydroxyflavanone-on-proliferation-invasion-and-migration-of-bladder-cancer-cells-in-vitro-via-blocking-akt-stat3-signaling-pathway
#7
JOURNAL ARTICLE
Jianning Zhu, Kaijie Wu, Yule Chen, Zhongyun Ning, Kai Zhang, Yiqing DU, Chen Ding, Xinyang Wang, Jinhai Fan
OBJECTIVE: To study the effect of 2'-hydroxyflavanone on proliferation, invasion and migration of bladder cancer cells and its mechanism. METHODS: MTT assay was used to detect the effect of 2'-hydroxyflavanone on proliferation of bladdercancer cells, and the proliferation inhibition rate was calculated. Wound healing assay and Transwell (TM); assay were conducted to study the effect of 2'-hydroxyflavanone on migration and invasion of bladder cancer cells, respectively...
March 2014: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://read.qxmd.com/read/16999630/endocytoscopy-novel-endoscopic-imaging-technology-for-in-situ-observation-of-bladder-cancer-cells
#8
JOURNAL ARTICLE
Takashi Ohigashi, Norihide Kozakai, Ryuichi Mizuno, Akira Miyajima, Masaru Murai
BACKGROUND AND PURPOSE: Recent advances in endoscopy have enabled microscopic imaging of live bladdercancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. PATIENTS AND METHODS: This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope...
September 2006: Journal of Endourology
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