Nathan A Brooks, Andrea Kokorovic, Lianchen Xiao, Justin T Matulay, Roger Li, Weranja K B Ranasinghe, Supriya Nagaraju, Yu Shen, Jianjun Gao, Neema Navai, Colin P N Dinney, H Barton Grossman, Ashish M Kamat
OBJECTIVES: To evaluate if the obesity paradox, wherein obesity portends worse overall prognosis for a disease but improved outcomes for patients receiving immunotherapy, exists for patients receiving bacillus Calmette-Guérin (BCG) in a contemporary cohort. PATIENTS AND METHODS: We performed an Institutional Review Board-approved database review to identify patients with non-muscle-invasive bladder cancer (NMIBC) completing at least an induction course of BCG. Clinicopathological variables collected included: body mass index (BMI), medications, and diabetes mellitus (DM)...
July 2021: BJU International