keyword
https://read.qxmd.com/read/37575989/comparison-between-sevoflurane-and-propofol-on-immunomodulation-in-an-in-vitro-model-of-sepsis
#21
JOURNAL ARTICLE
Tainá B Oliveira, Cassia L Braga, Denise Battaglini, Paolo Pelosi, Patricia R M Rocco, Pedro L Silva, Fernanda F Cruz
INTRODUCTION: Patients with sepsis often require sedation and/or anesthesia. Although the immunomodulatory effects of anesthetics have been increasingly recognized, the molecular mechanisms require better elucidation. We compared the effects of sevoflurane with propofol on the expression of pro- and anti-inflammatory biomarkers released by monocytes/macrophages and blood/bronchoalveolar lavage fluid (BALF) neutrophils, the phagocytic capacity of monocytes/ macrophages, and neutrophil migration, as well as mediators associated with alveolar epithelial and endothelial cells obtained from rats with sepsis...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37560211/comparison-analysis-of-safety-profiles-and-identification-of-risk-factors-for-postoperative-adverse-reactions-propofol-versus-sevoflurane-in-pediatric-anesthesia
#22
JOURNAL ARTICLE
Xuan Xu, Haodong Liu, Jie Yang, Maopeng Zhang
OBJECTIVE: To compare the safety profiles between propofol and sevoflurane in pediatric anesthesia and to investigate risk factors for postoperative adverse reactions. METHODS: The data of 194 children who received surgical treatment in Peking Union Medical College Hospital between January 2019 and May 2022 were analyzed retrospectively. According to the different anesthetic drugs the children received, they were divided into a control group (conventional anesthesia with sevoflurane, n=94) and an observation group (anesthesia with both propofol and sevoflurane, n=100)...
2023: American Journal of Translational Research
https://read.qxmd.com/read/37502467/comparison-of-the-efficacy-of-opioid-free-anesthesia-with-conventional-opioid-based-anesthesia-for-nasal-surgeries-a-prospective-randomized-parallel-arm-triple-blinded-study
#23
JOURNAL ARTICLE
Hariharan S S, Arul M Ramasamy, Aruna Parameswari, Rajesh Kumar Kodali V, Mahesh Vakamudi
Introduction In the setting of nasal surgeries, the use of opioid-free anesthesia involving the use of dexmedetomidine, and lignocaine is being investigated as a potential alternative to opioids. This combination of drugs provides sympatholysis, pain relief, and sedative properties, thereby aiming at reducing the negative effects commonly associated with opioid usage. The objective of this study is to evaluate and compare the effectiveness of opioid-free anesthesia using dexmedetomidine and lignocaine versus conventional opioid anesthesia with fentanyl for nasal surgeries...
July 2023: Curēus
https://read.qxmd.com/read/37498387/renal-safety-of-critical-care-sedation-with-sevoflurane-a-systematic-review-and-meta-analysis
#24
REVIEW
Ben Taylor, Timothy E Scott, James Shaw, Nachiappan Chockalingam
Volatile anesthetic agents are increasingly widely used for critical care sedation. There are concerns that sevoflurane presents a risk of renal injury when used in this role. RCTs comparing the use of critical care sevoflurane sedation with any control in humans were systematically identified using MEDLINE, Cochrane CENTRAL, web of Science, and CINAHL (until May 2022), if they presented comparative data on renal function or serum inorganic fluoride levels. Pooled SMDs (95% CI) were calculated where possible after assessment of quality with GRADE and risk of bias with ROB-2...
July 27, 2023: Journal of Anesthesia
https://read.qxmd.com/read/37373914/sedation-with-sevoflurane-versus-propofol-in-covid-19-patients-with-acute-respiratory-distress-syndrome-results-from-a-randomized-clinical-trial
#25
JOURNAL ARTICLE
Sara Martínez-Castro, Berta Monleón, Jaume Puig, Carolina Ferrer Gomez, Marta Quesada, David Pestaña, Alberto Balvis, Emilio Maseda, Alejandro Suárez de la Rica, Ana Monero Feijoo, Rafael Badenes
BACKGROUND: Acute respiratory distress syndrome (ARDS) related to COVID-19 (coronavirus disease 2019) led to intensive care units (ICUs) collapse. Amalgams of sedative agents (including volatile anesthetics) were used due to the clinical shortage of intravenous drugs (mainly propofol and midazolam). METHODS: A multicenter, randomized 1:1, controlled clinical trial was designed to compare sedation using propofol and sevoflurane in patients with ARDS associated with COVID-19 infection in terms of oxygenation and mortality...
May 31, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37291773/comparing-recovery-from-desflurane-and-sevoflurane-in-patients-with-different-body-fat-percentages-a-randomized-controlled-trial
#26
Silu Cao, Huijuan Wang, Lijun Tang, Guanghui An
INTRODUCTION: Increased body fat may influence the partition coefficients of inhaled anesthetics. We compared patient responses to desflurane and sevoflurane anesthesia, as measured by a quicker recovery and fewer complications, in patients with higher body fat percentages, not only obese people. METHODS: This study included 120 patients. Participants were stratified into low or high body fat percentages groups using bioelectrical impedance analysis and were randomized 1:1 to receive desflurane or sevoflurane as an inhaled anesthetic, recorded as Low-Desflurane, Low-Sevoflurane, High- Desflurane, and High-Sevoflurane...
April 7, 2023: Current Drug Delivery
https://read.qxmd.com/read/37291651/effects-of-dexmedetomidine-at-different-dosages-on-perioperative-haemodynamics-and-postoperative-recovery-quality-in-elderly-patients-undergoing-hip-replacement-surgery-under-general-anaesthesia-a-randomized-controlled-trial
#27
JOURNAL ARTICLE
Haitong Liu, Mingjie Gao, Yongfeng Zheng, Caixia Sun, Qinyuan Lu, Donghua Shao
BACKGROUND: Dexmedetomidine could provide some advantages to prevent postoperative complications in elderly patients undergoing under general anaesthesia. However, dexmedetomidine inhibits haemodynamics to some extent due to its sympathetic inhibition. OBJECTIVE: To evaluate the effects of different doses of dexmedetomidine on haemodynamics during surgery and recovery after general anaesthesia in elderly patients undergoing hip replacement. METHODS: This was a prospective randomized double-blind controlled clinical trial...
June 8, 2023: Trials
https://read.qxmd.com/read/37240959/comparison-of-the-incidence-of-postoperative-acute-kidney-injury-following-the-administration-of-remimazolam-or-sevoflurane-in-elderly-patients-undergoing-total-knee-arthroplasty-a-randomized-controlled-trial
#28
JOURNAL ARTICLE
Sangho Lee, Hee Yong Kang, Ye Na Ahn, Ann Hee You
BACKGROUND: We evaluated the incidence of postoperative acute kidney injury (AKI) and complications when remimazolam (RMMZ) or sevoflurane (SEVO) were used in elderly patients undergoing total knee arthroplasty. METHODS: Seventy-eight participants aged ≥65 were randomly allocated to either the RMMZ or SEVO group. The primary outcome was the incidence of AKI on postoperative day (POD) 2. The secondary outcomes included intraoperative heart rate (HR), blood pressure (BP), total drug administered, emergence time, postoperative complications on POD 2, and hospital length of stay (HLOS)...
May 1, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37188963/subanesthetic-dose-propofol-infusion-for-preventing-emergence-agitation-in-children-a-retrospective-observational-study
#29
JOURNAL ARTICLE
Tomoaki Miyake, Yoshihisa Miyamoto, Nobuhito Nakamura
PURPOSE: Anesthesia maintenance using propofol and a propofol bolus dose at the end of surgery have been shown to prevent emergence agitation (EA). However, the preventive effect of subanesthetic propofol infusion during sevoflurane anesthesia on EA remains unknown. We aimed to evaluate the effect of subanesthetic propofol infusion on EA in children. METHODS: We retrospectively compared the incidences of severe EA requiring pharmacological intervention in children who underwent adenoidectomy, tonsillectomy with or without adenoidectomy, or strabismus surgery between maintenance with sevoflurane alone (sevoflurane group) and maintenance with subanesthetic propofol with sevoflurane (combination group)...
August 2023: Journal of Anesthesia
https://read.qxmd.com/read/37181823/does-sevoflurane-sedation-in-pediatric-patients-lead-to-pseudo-leptomeningeal-enhancement-in-the-brain-on-3-tesla-magnetic-resonance-imaging
#30
JOURNAL ARTICLE
Kiran Hilal, Kumail Khandwala, Saima Rashid, Faheemullah Khan, Shayan Sirat Maheen Anwar
BACKGROUND: Prominent leptomeningeal contrast enhancement (LMCE) in the brain is observed in some pediatric patients during sedation for imaging. However, based on clinical history and cerebrospinal fluid analysis, the patients are not acutely ill and do not exhibit meningeal signs. Our study determined whether sevoflurane inhalation in pediatric patients led to this pattern of 'pseudo' LMCE (pLMCE) on 3 Tesla magnetic resonance imaging (MRI). AIM: To highlight the significance of pLMCE in pediatric patients undergoing enhanced brain MRI under sedation to avoid misinterpretation in reports...
April 28, 2023: World Journal of Radiology
https://read.qxmd.com/read/37083779/perioperative-management-and-drug-selection-for-sedated-anesthetized-patients-undergoing-mri-examination-a-review
#31
REVIEW
Xiaoyu Wang, XueQuan Liu, Junqiao Mi
In recent years, magnetic resonance imaging (MRI) technology has become an indispensable imaging tool owing to significant improvements in MRI that have opened up new diagnostic perspectives. Due to the closed environment, long imaging time, and need to remain still during the examination process, the examiner may cannot cooperate with the completion of the examination of the procedure, which increases the need for deep sedation or anesthesia. Achieving this can sometimes be challenging, especially in the special nontraditional environment of MRI equipment (unfamiliar and narrow spaces, away from patients, strong magnetic fields) and in special populations requiring sedation/anesthesia during examinations, which pose certain challenges for the perioperative anesthesia management of MRI...
April 21, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37033193/association-of-volatile-anesthesia-exposure-and-depth-with-emergence-agitation-and-delirium-in-children-prospective-observational-cohort-study
#32
JOURNAL ARTICLE
Yinan Zhang, Qiuying Zhang, Shan Xu, Xiaoxi Zhang, Wenxu Gao, Yu Chen, Zhaoqiong Zhu
BACKGROUND: Sevoflurane anesthesia is widely used in pediatric ambulatory surgery. However, emergency agitation (EA) and emergency delirium (ED), as major complications following sevoflurane anesthesia in children, pose risks to surgery and prognosis. Identifying the high risk of EA/ED, especially anesthesia exposure and the depth of anesthesia, may allow preemptive treatment. METHODS: A total of 137 patients were prospectively enrolled in this single-center observational cohort study to assess the incidence of EA or ED...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37010956/anesthetic-management-and-deep-sedation-after-emergence-from-general-anesthesia-a-retrospective-cohort-study
#33
JOURNAL ARTICLE
Atousa Deljou, Jalal Soleimani, David P Martin, Darrell R Schroeder, Juraj Sprung, Toby N Weingarten
BACKGROUND: Residual deep sedation during anesthesia recovery may predict postoperative complications. We examined the incidence and risk factors for deep sedation after general anesthesia. METHODS: We retrospectively reviewed health records of adults who underwent procedures with general anesthesia and were admitted to the postanesthesia care unit from May 2018 to December 2020. Patients were dichotomized by Richmond Agitation-Sedation Scale (RASS) score: ≤-4 (deeply sedated/unarousable) or ≥-3 (not deeply sedated)...
June 1, 2023: Anesthesia and Analgesia
https://read.qxmd.com/read/36819361/patient-comfort-during-postop-period-in-breast-cancer-surgeries-a-randomized-controlled-trial-comparing-opioid-and-opioid-free-anesthesia
#34
JOURNAL ARTICLE
Aravindhan Krishnasamy Yuvaraj, Balasubramaniam Gayathri, Natarajan Balasubramanian, Gunaseelan Mirunalini
BACKGROUND: Anesthetic management practices have advanced to opioid-free anesthesia (OFA) often replacing opioids in oncologic surgeries. The study was conducted to find the quality of recovery (QoR) of patients undergoing breast cancer surgeries receiving OFA. METHODS: A double-blinded, randomized controlled study was conducted with 60 patients randomized to group OFA and group OA (opioid anesthesia). Group OFA received one-time dosing of ketamine 0.3 mg/kg, lignocaine 1...
January 2023: Curēus
https://read.qxmd.com/read/36769718/inhaled-sedation-with-volatile-anesthetics-for-mechanically-ventilated-patients-in-intensive-care-units-a-narrative-review
#35
REVIEW
Khaled Ahmed Yassen, Matthieu Jabaudon, Hussah Abdullah Alsultan, Haya Almousa, Dur I Shahwar, Fatimah Yousef Alhejji, Zainab Yaseen Aljaziri
Inhaled sedation was recently approved in Europe as an alternative to intravenous sedative drugs for intensive care unit (ICU) sedation. The aim of this narrative review was to summarize the available data from the literature published between 2005 and 2023 in terms of the efficacy, safety, and potential clinical benefits of inhaled sedation for ICU mechanically ventilated patients. The results indicated that inhaled sedation reduces the time to extubation and weaning from mechanical ventilation and reduces opioid and muscle relaxant consumption, thereby possibly enhancing recovery...
January 30, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36759290/comparison-of-alfaxalone-and-propofol-on-haematological-and-serum-biochemical-variables-in-cats-undergoing-radiotherapy-with-sevoflurane-maintenance
#36
JOURNAL ARTICLE
Maximilian Körner, Carla Rohrer Bley, Rima Bektas, Barbara Riond, Friederike Wolf, Valeria Meier
OBJECTIVE: To evaluate effects of repeated alfaxalone or propofol administration on haematological and serum biochemical variables in cats undergoing radiotherapy. STUDY DESIGN: Prospective, block-randomized, clinical trial. ANIMALS: A group of 39 client-owned cats. METHODS: After butorphanol (0.2 mg kg-1 ) and midazolam (0.1 mg kg-1 ) sedation, cats were randomly assigned to receive either alfaxalone or propofol for induction of anaesthesia and sevoflurane maintenance...
March 2023: Veterinary Anaesthesia and Analgesia
https://read.qxmd.com/read/36754992/effect-of-midazolam-in-autism-spectrum-disorder-a-retrospective-observational-analysis
#37
JOURNAL ARTICLE
Hiroshi Hanamoto, Yohsuke Hirose, Midori Toyama, Chizuko Yokoe, Aiko Oyamaguchi, Hitoshi Niwa
BACKGROUND: While midazolam is commonly used as premedication for uncooperative patients, its effects are difficult to predict in patients with autism spectrum disorder for whom abnormalities in gamma-aminobutyric acid have been reported. This study aimed to investigate the influence of autism spectrum disorder on the effect of midazolam when used as premedication. METHODS: This retrospective observational study was performed between April 2017 and August 2018. Before inducing general anesthesia with sevoflurane for dental treatment, 390 uncooperative patients received premedication with midazolam...
May 2023: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/36750473/anesthetic-management-of-a-patient-with-osler-weber-rendu-syndrome-with-multiple-pulmonary-arteriovenous-malformations-and-pheochromocytoma-for-femoral-artificial-bone-replacement-a-case-report
#38
JOURNAL ARTICLE
Toshiharu Hiyoshi, Kazuyoshi Shimizu, Satoshi Kimura, Toshiki Naritani, Hiroshi Morimatsu
BACKGROUND: Osler-Weber-Rendu syndrome is characterized by mucocutaneous telangiectasia and arteriovenous malformations in organs. Anesthesia for patients with Osler-Weber-Rendu syndrome is challenging due to complications and physiological changes. CASE PRESENTATION: The case was a 49-year-old female with Osler-Weber-Rendu syndrome, multiple pulmonary arteriovenous malformations and pheochromocytoma who presented for femoral bone head fracture with metastatic adenocarcinoma...
February 8, 2023: JA Clinical Reports
https://read.qxmd.com/read/36738631/diabetes-insipidus-related-to-sedation-in-the-intensive-care-unit-a-review-of-the-literature
#39
REVIEW
Molly B Kraus, Kahlin Leuzinger, Emily Reynolds, Alice Gallo de Moraes, Julianna Smith, Emily E Sharpe, Jaxon Quillen, Heidi Kosiorek, Monica W Harbell
PURPOSE: To identify cases of diabetes insipidus (DI) related to sedation in the ICU to determine which medications pose the greatest risk and understand patterns of presentation. MATERIALS AND METHODS: We searched PubMed, Embase, Scopus, Google Scholar, and Web of Science. Search terms included "polyuria," "diabetes insipidus," "hypnotics and sedatives," "sedation," as well as individual medications. Case reports or series involving DI or polyuria related to sedation in the ICU were identified...
June 2023: Journal of Critical Care
https://read.qxmd.com/read/36727845/performance-of-the-sedline-monitor-age-dependency-and-time-delay
#40
JOURNAL ARTICLE
David P Obert, Frederick Schneider, Gerhard Schneider, Falk von Dincklage, Pablo Sepulveda, Paul S García, Stephan Kratzer, Matthias Kreuzer
BACKGROUND: Devices monitoring the hypnotic component of general anesthesia can help to guide anesthetic management. The main purposes of these devices are the titration of anesthesia dose. While anesthesia at low doses can result in awareness with intraoperative memory formation, excessive administration of anesthetics may be associated with an increased risk of postoperative neurocognitive disorder. We have previously shown for various indices that they are significantly influenced by the patient's age and that the monitors have a significant time delay...
October 1, 2023: Anesthesia and Analgesia
keyword
keyword
117131
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.