keyword
https://read.qxmd.com/read/38490897/carbon-footprint-of-total-intravenous-and-inhalation-anesthesia-in-the-transcatheter-aortic-valve-replacement-procedure
#1
JOURNAL ARTICLE
Lei Yang, Joshua Hubert, Samwel Gitundu, Ethan Brovman, Frederick Cobey
OBJECTIVES: To quantify and compare the emissions for deep sedation with total intravenous anesthesia (TIVA) and general anesthesia with inhaled agents during the transcatheter aortic valve replacement procedure. DESIGN: A retrospective study. SETTING: A tertiary hospital in Boston, Massachusetts. PARTICIPANTS: The anesthesia records of 604 consecutive patients who underwent the transcatheter aortic valve replacement procedure between January 1, 2018, and March 31, 2022, were reviewed and analyzed...
February 22, 2024: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/38485879/prospective-observational-study-of-volatile-sedation-with-sevoflurane-after-aneurysmal-subarachnoid-hemorrhage-using-the-sedaconda-anesthetic-conserving-device
#2
JOURNAL ARTICLE
Jan Leppert, Jan Küchler, Andreas Wagner, Niclas Hinselmann, Claudia Ditz
BACKGROUND: Volatile sedation is still used with caution in patients with acute brain injury because of safety concerns. We analyzed the effects of sevoflurane sedation on systemic and cerebral parameters measured by multimodal neuromonitoring in patients after aneurysmal subarachnoid hemorrhage (aSAH) with normal baseline intracranial pressure (ICP). METHODS: In this prospective observational study, we analyzed a 12-h period before and after the switch from intravenous to volatile sedation with sevoflurane using the Sedaconda Anesthetic Conserving Device with a target Richmond Agitation Sedation Scale score of - 5 to - 4...
March 14, 2024: Neurocritical Care
https://read.qxmd.com/read/38454342/minimal-alveolar-concentration-of-sevoflurane-in-combination-with-remimazolam-in-adults-during-laryngeal-mask-insertion-an-up-down-sequential-allocation-study
#3
JOURNAL ARTICLE
Yan Huang, HongYu Liao, LinJi Li, Juan Xu, PingPing Jiang, YanXia Guo, KunPeng Liu
BACKGROUND: Remimazolam is a novel ultrashort-acting intravenous benzodiazepine sedative-hypnotic. The combination of remimazolam and sevoflurane does not increase respiratory sensitivity, produce bronchospasm, or cause other adverse conditions. We aimed to observe the effects of different remimazolam doses on the minimum alveolar concentration (MAC) of sevoflurane at end-expiration during laryngeal mask insertion and evaluate the effect of sex on the efficacy of the combination of remimazolam on the suppression of laryngeal mask insertion in adult patients...
March 8, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38448835/the-role-of-perioperative-sedative-anesthetics-in-preventing-postoperative-delirium-a-systematic-review-and-network-meta-analysis-including-6679-patients
#4
JOURNAL ARTICLE
Jin-Xiang Huang, Shan-Shan Zhang, Shu-Xian Wang, Da-Shuang Xi, Fang-Ru Luo, Cheng-Jiang Liu, Hong Li
OBJECTIVE: Postoperative delirium is a common and debilitating complication that significantly affects patients and their families. The purpose of this study is to investigate whether there is an effective sedative that can prevent postoperative delirium while also examining the safety of using sedatives during the perioperative period. METHODS: The net-meta analysis was used to compare the incidence of postoperative delirium among four sedatives: sevoflurane, propofol, dexmedetomidine, and midazolam...
March 6, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38365169/effect-of-dexmedetomidine-infusion-on-post-operative-sleep-disturbances-in-women-with-breast-cancer-a-monocentric-randomized-controlled-double-blind-trial
#5
JOURNAL ARTICLE
Yu-Shan Dong, Mao-San Wang, Wen-Zhan Li, Kai Zhao, Xiao-Jie Cui, Yan-Ming Yang, Xing-Yu Geng, Yu-Tian Pu, Zi-Wei Hu, Can Fang, Gao-Chao Lv, Su Liu, Xiu-Xia Chen
BACKGROUND: Most women with breast cancer are prone to post-operative sleep disturbances (POSD). Little is known about the differences between sevoflurane and propofol combined with dexmedetomidine on POSD in the same context. We investigated the effect of intra-operative sevoflurane or propofol combined with intravenous dexmedetomidine on the incidence of POSD and post-operative sleep structures. METHODS: A monocentric, randomized-controlled, double-blind trial...
February 14, 2024: Anaesthesia, Critical Care & Pain Medicine
https://read.qxmd.com/read/38309642/guidelines-for-inhaled-sedation-in-the-icu
#6
JOURNAL ARTICLE
F García-Montoto, D Paz-Martín, D Pestaña, M Soro, J M Marcos Vidal, R Badenes, A Suárez de la Rica, T Bardi, A Pérez-Carbonell, C García, J A Cervantes, M P Martínez, J L Guerrero, J V Lorente, J Veganzones, M Murcia, F J Belda
INTRODUCTION AND OBJECTIVES: Sedation is used in intensive care units (ICU) to improve comfort and tolerance during mechanical ventilation, invasive interventions, and nursing care. In recent years, the use of inhalation anaesthetics for this purpose has increased. Our objective was to obtain and summarize the best evidence on inhaled sedation in adult patients in the ICU, and use this to help physicians choose the most appropriate approach in terms of the impact of sedation on clinical outcomes and the risk-benefit of the chosen strategy...
February 1, 2024: Revista española de anestesiología y reanimación
https://read.qxmd.com/read/38285231/effects-on-mechanical-power-of-different-devices-used-for-inhaled-sedation-in-a-bench-model-of-protective-ventilation-in-icu
#7
JOURNAL ARTICLE
Pierre-Louis Pellet, Neven Stevic, Florian Degivry, Bruno Louis, Laurent Argaud, Claude Guérin, Martin Cour
BACKGROUND: Inhaled sedation during invasive mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) has received increasing attention. However, inhaled sedation devices increase dead-space ventilation and an undesirable effect is the increase in minute ventilation needed to maintain CO2 removal. A consequence of raising minute ventilation is an increase in mechanical power (MP) that can promote lung injury. However, the effect of inhaled sedation devices on MP remains unknown...
January 29, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38256871/an-in-silico-investigation-of-the-molecular-interactions-between-volatile-anesthetics-and-actin
#8
JOURNAL ARTICLE
Barbara Truglia, Nicola Carbone, Ibrahim Ghadre, Sara Vallero, Marinella Zito, Eric Adriano Zizzi, Marco Agostino Deriu, J A Tuszynski
Volatile anesthetics (VAs) are medicinal chemistry compounds commonly used to enable surgical procedures for patients who undergo painful treatments and can be partially or fully sedated, remaining in an unconscious state during the operation. The specific molecular mechanism of anesthesia is still an open issue, but scientific evidence supports the hypothesis of the involvement of both putative hydrophobic cavities in membrane receptors as binding pockets and interactions between anesthetics and cytoplasmic proteins...
December 26, 2023: Pharmaceuticals
https://read.qxmd.com/read/38086759/effect-of-inhaled-sevoflurane-on-pediatric-cerebrospinal-fluid-pressure-during-lumbar-puncture-implications-for-intracranial-hypertension
#9
JOURNAL ARTICLE
Shawn C Aylward, Brandon S Aylward, Gina M Fedel
Objective: To determine influence of sevoflurane on changes in cerebrospinal fluid pressure in children presenting for lumbar puncture. Methods: Cerebrospinal fluid pressure, end tidal carbon dioxide, and end tidal sevoflurane concentration measurements were obtained at 2-minute intervals for a total of 10 minutes (T0 to T5). Because of concerns regarding patient safety and comfort, the study measurements were completed at the end of the lumbar procedure, starting with the closing pressure and when sevoflurane was stopped...
December 12, 2023: Journal of Child Neurology
https://read.qxmd.com/read/38071152/effect-of-prolonged-sedation-with-dexmedetomidine-midazolam-propofol-and-sevoflurane-on-sleep-homeostasis-in-rats
#10
JOURNAL ARTICLE
Brian H Silverstein, Anjum Parkar, Trent Groenhout, Zuzanna Fracz, Anna M Fryzel, Christopher W Fields, Amanda Nelson, Tiecheng Liu, Giancarlo Vanini, George A Mashour, Dinesh Pal
BACKGROUND: Sleep disruption is a common occurrence during medical care and is detrimental to patient recovery. Long-term sedation in the critical care setting is a modifiable factor that affects sleep, but the impact of different sedative-hypnotics on sleep homeostasis is not clear. METHODS: We conducted a systematic comparison of the effects of prolonged sedation (8 h) with i.v. and inhalational agents on sleep homeostasis. Adult Sprague-Dawley rats (n=10) received dexmedetomidine or midazolam on separate days...
December 8, 2023: British Journal of Anaesthesia
https://read.qxmd.com/read/38058786/the-advantages-of-inhalational-sedation-using-an-anesthetic-conserving-device-versus-intravenous-sedatives-in-an-intensive-care-unit-setting-a-systematic-review
#11
REVIEW
Zohair Al Aseri, Mariam Ali Alansari, Sara Ali Al-Shami, Bayan Alaskar, Dhuha Aljumaiah, Alyaa Elhazmi
BACKGROUND: Sedation is fundamental to the management of patients in the intensive care unit (ICU). Its indications in the ICU are vast, including the facilitating of mechanical ventilation, permitting invasive procedures, and managing anxiety and agitation. Inhaled sedation with halogenated agents, such as isoflurane or sevoflurane, is now feasible in ICU patients using dedicated devices/systems. Its use may reduce adverse events and improve ICU outcomes compared to conventional intravenous (IV) sedation in the ICU...
2023: Annals of Thoracic Medicine
https://read.qxmd.com/read/38052328/anesthesia-choice-and-its-potential-impact-on-endoluminal-functional-lumen-imaging-probe-measurements-in-esophageal-motility-disorders
#12
JOURNAL ARTICLE
Andrew Canakis, David U Lee, Jennifer L Grossman, Daniel G Hwang, Jennifer Wellington, Alexander H Yang, Gregory H Fan, Grace E Kim, Raymond E Kim
BACKGROUND AND AIMS: The widespread use of peroral endoscopic myotomy (POEM) has revolutionized the management of esophageal motility disorders (EMDs). The introduction of an endoluminal functional lumen imaging probe (EndoFLIP) can serve as a complimentary diagnostic tool to assess the mechanical properties (i.e., pressure, diameter, distensibility and topography) of the esophagus. During EndoFLIP measurements, different anesthesia techniques may induce variable degrees of neuromuscular blockade, potentially affecting esophageal motility and altering the results of EndoFLIP metrics...
December 3, 2023: Gastrointestinal Endoscopy
https://read.qxmd.com/read/38024006/the-role-of-dexmedetomidine-in-airway-management-for-tracheostomy-in-pediatric-patient-with-obstructed-airway-due-to-diphtheria-a-case-report
#13
Andy Omega, Faradila Ramadian, Putri Nurra Kusumawardhany Hakim
INTRODUCTION: Diphtheria is an infectious disease caused by exotoxin-producing Corynebacterium diphteriae and was a leading cause of death in childhood during the prevaccine era. This toxin is usually localized in the upper respiratory tract and may cause fatal airway obstruction. Many have used orotracheal intubation to secure the airway in diphtheria cases. However, the efficacy of tracheostomy under sedation while maintaining spontaneous ventilation and analgesia using trans-tracheal and superficial cervical block remains to be elucidated...
August 2023: Anesthesiology and Pain Medicine
https://read.qxmd.com/read/37847389/-nephrogenic-diabetes-insipidus-after-inhalation-sedation-with-sevoflurane-in-a%C3%A2-patient-with-covid-19-associated-acute-respiratory-distress-syndrome
#14
JOURNAL ARTICLE
Johannes Reins, Florian Balling, Christoph Baader, Elfriede Böck, Wolfgang Schöniger, Rene van Erp, Sebastian Eff, Sebastian Hafner
No abstract text is available yet for this article.
October 17, 2023: Anaesthesiologie
https://read.qxmd.com/read/37835045/usage-of-inhalative-sedative-for-sedation-and-treatment-of-patient-with-severe-brain-injury-in-germany-a-nationwide-survey
#15
JOURNAL ARTICLE
Svea Roxana Roggenbuck, André Worm, Martin Juenemann, Christian Claudi, Omar Alhaj Omar, Marlene Tschernatsch, Hagen B Huttner, Patrick Schramm
Brain injured patients often need deep sedation to prevent or treat increased intracranial pressure. The mainly used IV sedatives have side effects and/or high context-sensitive half-lives, limiting their use. Inhalative sedatives have comparatively minor side effects and a brief context-sensitive half-life. Despite the theoretical advantages, evidence in this patient group is lacking. A Germany-wide survey with 21 questions was conducted to find out how widespread the use of inhaled sedation is. An invitation for the survey was sent to 226 leaders of intensive care units (ICU) treating patients with brain injury as listed by the German Society for Neurointensive Care...
October 8, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37789407/anaesthetic-management-and-complications-of-a-humboldt-penguin-spheniscus-humboldti-undergoing-diagnostic-imaging
#16
JOURNAL ARTICLE
Patricia Romero, Flavia Restitutti, Niamh McGill, Seamus Hoey, Rachel C Bennett
BACKGROUND: The presence of a tracheal septum dividing the trachea into two makes intubation one of the main challenges of penguin anaesthesia. Differences in the length and location of the aforementioned tracheal septum have been described in some penguin species. However, to the best of the authors' knowledge, it has not been reported in Humboldt penguins (Spheniscus humboldti). Therefore, one of the aims of this publication is to report the septal position in this Humboldt penguin...
October 4, 2023: Irish Veterinary Journal
https://read.qxmd.com/read/37780555/sevoflurane-sedation-in-covid-19-acute-respiratory-distress-syndrome-an-observational-study-with-a-propensity-score-matching-model
#17
JOURNAL ARTICLE
Guglielmo Consales, Iacopo Cappellini, Benedetta Freschi, Laura Campiglia, Maddalena Parise, Lucia Zamidei
INTRODUCTION: The management of severe COVID-19-induced acute respiratory distress syndrome (C-ARDS) often involves deep sedation. This study evaluated the efficacy of sevoflurane, a volatile anesthetic, as an alternative to traditional intravenous sedation in this patient population. METHODS: This single-center, retrospective cohort study enrolled 112 patients with C-ARDS requiring invasive mechanical ventilation. A propensity score matching model was utilized to pair 56 patients receiving sevoflurane sedation with 56 patients receiving intravenous sedation...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37713329/postanesthesia-care-unit-recovery-time-according-to-volatile-anesthetic-used-in-clinical-practice
#18
JOURNAL ARTICLE
Juraj Sprung, Atousa Deljou, David O Warner, Darrell R Schroeder, Toby N Weingarten
BACKGROUND: Whether volatile anesthetic solubility affects postanesthesia recovery time in clinical practice is unclear. We investigated the association among 3 volatile agents and 2 clinically relevant outcomes-postanesthesia care unit (PACU) recovery time (time from PACU admission to fulfillment of discharge criteria) and oversedation (Richmond Agitation-Sedation Scale score ≤-3)-as a potential contributor to delaying PACU discharge. The volatile agents studied were isoflurane, desflurane, and sevoflurane...
November 1, 2023: Anesthesia and Analgesia
https://read.qxmd.com/read/37654338/comparison-of-the-sevoflurane-versus-desflurane-anaesthesia-on-the-recovery-of-airway-reflexes-and-cognitive-function-an-original-research
#19
JOURNAL ARTICLE
Anish Nelson, S Sudhakar, Jagannath Mishra, Hemanth Kumar Tirupathi, Vishnu Gowtham Marella, Vishal S Kudagi
BACKGROUND AND OBJECTIVES: Sevoflurane and desflurane virtually equally dissolve in blood gases, yet current research suggests that desflurane helps in a quick return of airway reflex than sevoflurane however the return of cognitive activity fluctuates greatly. In order to compare the lengths of time required to recover after sevoflurane and desflurane anesthesia, the current research was conducted. MATERIALS AND METHODS: Current study was randomized that included 100 subjects who were posted for cholecystectomy (elective)...
July 2023: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/37609002/diffuse-alveolar-hemorrhage-induced-by-inhaled-sevoflurane-case-report-and-literature-review
#20
Jaime H Jordan, Santiago Pedroza, Einar S Billefals, Gustavo Cruz
Diffuse alveolar hemorrhage secondary to sevoflurane inhalation is a rare condition. It should be considered in postoperative patients presenting symptoms of hemoptysis, hypoxemia, or radiographic alveolar infiltrates. We present the case of a 42-year-old man who experienced a diffuse alveolar hemorrhage following sedation with sevoflurane during a low-risk orthopedic procedure. Initially, the patient presented hemoptysis, hypoxemia, and dyspnea. X-ray findings suggested alveolar hemorrhage and the diagnosis was confirmed with fiberoptic bronchoscopy...
2023: Respiratory Medicine Case Reports
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