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https://www.readbyqxmd.com/read/28635610/chemical-components-antioxidant-potential-and-hepatoprotective-effects-of-artemisia-campestris-essential-oil-against-deltamethrin-induced-genotoxicity-and-oxidative-damage-in-rats
#1
Mongi Saoudi, Marwa Ncir, Manel Ben Ali, Malek Grati, Kamel Jamoussi, Noureddine Allouche, Abdelfattah El Feki
In the present study, we evaluated the antioxidant potential of Artemisia campestris essential oil (ACEO) and the possible protective effects against deltamethrin induced hepatic toxic effects. The ACEO showed radical scavenging activity with IC50 = 47.66 ± 2.51 µg/ml, ferric reducing antioxidant power (FRAP) potential (EC50 = 5.36 ± 0.77 µg/ml), superoxide scavenging activity (IC50 = 0.175 ± 0.007 µg/ml) and ˙OH scavenging activity (IC50 = 0.034 ± 0.007 µg/ml). The obtained results of phenolic profile demonstrated that phenolic compounds are the major contributor to the antioxidant activity of ACEO...
July 2017: General Physiology and Biophysics
https://www.readbyqxmd.com/read/28631923/influence-of-ingesting-a-flavonoid-rich-supplement-on-the-metabolome-and-concentration-of-urine-phenolics-in-overweight-obese-women
#2
David C Nieman, Sivapriya Ramamoorthy, Colin D Kay, Courtney L Goodman, Christopher R Capps, Zach L Shue, Nicole Heyl, Mary H Grace
This study evaluated the effect of ingesting a flavonoid-rich supplement (329 mg/d) on total urine phenolics and shifts in plasma metabolites in overweight/obese female adults using untargeted metabolomics procedures. Participants (N=103, 18-65 y, BMI ≥ 25 kg/m2) were randomized to flavonoid (F) or placebo (P) groups for 12 weeks, with blood and 24-h urine samples collected pre-study, 4- and 12-weeks in a parallel design. Supplements were prepared as chewable tablets, and included vitamin C, wild bilberry fruit extract, green tea leaf extract, quercetin, caffeine, and omega 3 fatty acids...
June 20, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28631823/a-comparative-study-between-labeling-and-reality-the-case-of-phytochemical-composition-of-commercial-pomegranate-based-products
#3
Marina Cano-Lamadrid, Leontina Lipan, Ángel Calín-Sánchez, Francisca Hernández, Ángel A Carbonell-Barrachina
Manufacturers are deeply involved in the development of new pomegranate-based products, which have acquired great prestige due to many studies proving their potential health benefits. Commercial pomegranate products including capsules and supplements and juices and nectars were assayed. The contents of the key phytochemical compounds (punicalagin, ellagic acid, and total polyphenolic content) and the associated antioxidant capacity (DPPH(•) , ABTS(•+) , and FRAP) were analyzed. The experimental ranges of punicalagin and ellagic acid contents were 0...
June 20, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28631525/polyphenol-profile-by-uhplc-ms-ms-anti-glycation-antioxidant-and-cytotoxic-activities-of-several-samples-of-propolis-from-the-northeastern-semi-arid-region-of-brazil
#4
Jadriane de Almeida Xavier, Iara Barros Valentim, Fabiana O S Camatari, Alberto M M de Almeida, Henrique Fonseca Goulart, Jamylle Nunes de Souza Ferro, Emiliano de Oliveira Barreto, Bruno Coelho Cavalcanti, Carla B G Bottoli, Marília Oliveira Fonseca Goulart
CONTEXT: Propolis has promising biological activities. Propolis samples from the Northeast of Bahia, Brazil - sample A from Ribeira do Pombal and B, from Tucano - were investigated, with new information regarding their biological activities. OBJECTIVE: This paper describes the chemical profile, antioxidant, anti-glycation and cytotoxic activities of these propolis samples. MATERIAL AND METHODS: Ethanol extracts of these propolis samples (EEP) and their fractions were analyzed to determine total phenolic content (TPC); antioxidant capacity through DPPH(•), FRAP and lipid peroxidation; anti-glycation activity, by an in vitro glucose (10 mg/mL) bovine serum albumine (1 mg/mL) assay, during 7 d; cytotoxic activity on cancer (SF295, HCT-116, OVCAR-8, MDA-MB435, MX-1, MCF7, HL60, JURKAT, MOLT-4, K562, PC3, DU145) and normal cell lines (V79) at 0...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28631391/myosin-substitution-rate-is-affected-by-the-amount-of-cytosolic-myosin-in-cultured-muscle-cells
#5
Koichi Ojima, Emi Ichimura, Yuya Yasukawa, Mika Oe, Susumu Muroya, Takahiro Suzuki, Jun-Ichi Wakamatsu, Takanori Nishimura
In striated muscles, approximately 300 myosin molecules form a single thick filament in myofibrils. Each myosin is continuously displaced by another myosin to maintain the thick filament structure. Our previous study using a fluorescence recovery after photobleaching (FRAP) technique showed that the myosin replacement rate is decreased by inhibition of protein synthesis, but myosin is still exchangeable. This result prompted us to examine whether myosin in the cytoplasm is involved in myosin replacement in myofibrils...
June 19, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28628845/serum-antioxidant-capacity-and-oxidative-damage-in-clinical-and-subclinical-canine-ehrlichiosis
#6
Camila Peres Rubio, Zeki Yilmaz, Silvia Martínez-Subiela, Meric Kocaturk, Josefa Hernández-Ruiz, Ebru Yalcin, Asta Tvarijonaviciute, Damián Escribano, Jose Joaquín Ceron
The objective of this study was to evaluate and compare the antioxidant response and the products of oxidative damage analysed by various assays in clinical and subclinical canine monocytic ehrlichiosis (CME). For this purpose, four assays to measure the total serum antioxidant capacity (TAC), such as the cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of plasma (FRAP), trolox equivalent antioxidant capacity (TEAC) using acidic medium (TEACA), and the TEAC using the horseradish peroxidase (TEACH) were used...
June 12, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28627252/phytochemical-and-antioxidant-properties-of-some-cassia-species
#7
Firdose R Kolar, Chaya L Gogi, Mairunisabegum M Khudavand, Meera S Choudhari, Sindhu B Patil
In this study, the antioxidant activity of aqueous and ethanol extracts of four plants from the genus Cassia were evaluated by various antioxidant assays, including ferric reducing antioxidant power (FRAP), DPPH free radical scavenging, metal chelating activity, phosphomolybdenum reducing power, hydrogen peroxide radical scavenging, hydroxyl radical scavenging, deoxyribose degradation and β-carotene bleaching assay. The various antioxidant activities were compared to standard antioxidant such as ascorbic acid...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28623844/lc-ms-ms-characterization-anti-inflammatory-effects-and-antioxidant-activities-of-polyphenols-from-different-tissues-of-korean-petasites-japonicus-meowi
#8
Jin Young Choi, Kebede Taye Desta, Venu Venkatarame Gowda Saralamma, Sung Joong Lee, Soo Jung Lee, Seong Min Kim, Anjugam Paramanantham, Ho Jeong Lee, Yun-Hi Kim, Ho-Chul Shin, Jae-Han Shim, Sung Chul Shin, Gon-Sup Kim, A M Abd El-Aty
The Korean Petasites japonicus is a perennial plant used in folk medicine as a remedy for many diseases and popularly consumed as spring greens. Ten polyphenols were characterized from the leaves, stems, and roots of this plant via high-performance liquid chromatography-tandem mass spectrometry. Individual polyphenols were quantified for the first time using calibration curves of six structurally related external standards. Validation data indicated that correlation coefficients (R(2) ) were ≥ 0.9702 for all standards...
June 17, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28618209/chemical-compositions-antioxidant-and-antimicrobial-activities-of-essential-oil-of-psidium-guajava-l-leaves-from-different-geographic-regions-in-china
#9
Lu Wang, Yanan Wu, Tao Huang, Kan Shi, Zhenqiang Wu
Hydrodistilled essential oils (EO) of Psidium guajava L. leaves from different regions in China were analyzed by GC and GC/MS. The samples from Guangdong province displayed high EO yields (0.61-0.75%, v/w). A total of 50 components, representing over 98.00% of the EOs, were identified and semi-quantitatived. The major constituents of EOs included β-caryophyllen (17.17-31.38%), γ-gurjunene (9.17-15.22%), τ-cadinol (1.35-10.02%) and calamenene (2.13-7.80%). The terpenoids in all sample oils were dominated by sesquiterpenes hydrocarbons (70...
June 15, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28614371/chemical-characterization-and-extractives-composition-of-heartwood-and-sapwood-from-quercus-faginea
#10
Isabel Miranda, Vicelina Sousa, Joana Ferreira, Helena Pereira
Heartwood and sapwood of Quercus faginea were evaluated in relation to summative chemical composition and non-polar and polar extracts composition, including an assessment of antioxidant properties (DPPH and FRAP). Twenty trees from two sites in Portugal were analysed. Heartwood had approximately two times more solvent extractible compounds than sapwood (on average 19.0% and 9.5%). The lipophilic extractible compounds were below 1%, and most of them were polar e.g. ethanol-soluble compounds corresponded to 65% of total extractives in heartwood and 43% in sapwood...
2017: PloS One
https://www.readbyqxmd.com/read/28613901/characterization-of-phenolic-compounds-from-early-and-late-ripening-sweet-cherries-and-their-antioxidant-and-antifungal-activities
#11
Meng Wang, Nan Jiang, Yao Wang, Dongmei Jiang, Xiaoyuan Feng
Early and late ripening sweet cherries were characterized for phenolic acids, and also their antioxidant capacity and potential antifungal effects were investigated. Free, conjugated and bound phenolics were identified and quantified using UPLC-MS/MS. Our results indicated that the early ripening cultivars contained higher free phenolic, which positive related to remarkable antioxidant properties and the inhibition effects on A. alternata and tenuazonic acid (TeA) accumulation. However, conjugated phenolics of the late ripening cultivars, mainly including caffeic, 2, 3, 4-trihydroxybenzoic, p-coumaric and pyrocatechuic acids, achieved the highest antifungal effects, and almost completely inhibited the A...
June 14, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28613438/uhplc-esi-hr-ms-ms-profiling-of-phenolics-from-tunisian-lycium-arabicum-boiss-antioxidant-and-anti-lipase-activities-evaluation
#12
Marwa Affes, Jawhar Fakhfakh, Ines Douad, Vincent Brieudes, Maria Halabalaki, Abdelfattah El Feki, Noureddine Allouche
This study was performed in the aim to evaluate 9 different extracts from Tunisian L. arabicum for their total phenolic (TPC) and total flavonoid (TFC) contents, phytochemical analyses as well as their antioxidant and anti-lipase activities. The in vitro antioxidant property was investigated using three complementary methods (DPPH, Ferric reducing antioxidant capacity (FRAP) and β-carotene-linoleic acid bleaching assays) while anti-lipase activity was evaluated using 4-methylumbelliferyl oleate method. From all of the tested extracts the most potent found to be the polar methanol extracts especially those of stems and leaves...
June 14, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28612608/higher-antioxidant-activity-total-flavonols-and-specific-quercetin-glucosides-in-two-different-onion-allium-cepa-l-varieties-grown-under-organic-production-results-from-a-6-year-field-study
#13
Feiyue Ren, Kim Reilly, Joseph P Kerry, Michael Gaffney, Mohammad Hossain, Dilip K Rai
We carried out a 6-year study to assess the effect of conventional, organic, and mixed cultivation practices on bioactive compounds (flavonoids, anthocyanins) and antioxidant capacity in onion. Total flavonoids, total anthocyanins, individual flavonols, individual anthocyanins, and antioxidant activity were measured in two varieties ('Hyskin' and 'Red Baron') grown in a long-term split-plot factorial systems comparison trial. This is the first report of repeated measurements of bioactive content over an extensive time period in a single crop type within the same trial...
June 14, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28604646/effect-of-supercritical-carbon-dioxide-extraction-parameters-on-the-biological-activities-and-metabolites-present-in-extracts-from-arthrospira-platensis
#14
Diego A Esquivel-Hernández, José Rodríguez-Rodríguez, Sara P Cuéllar-Bermúdez, J Saúl García-Pérez, Elena I Mancera-Andrade, Jade E Núñez-Echevarría, Aura Ontiveros-Valencia, Magdalena Rostro-Alanis, Rebeca M García-García, J Antonio Torres, Wei Ning Chen, Roberto Parra-Saldívar
Arthrospira platensis was used to obtain functional extracts through supercritical carbon dioxide extraction (SFE-CO₂). Pressure (P), temperature (T), co-solvent (CX), static extraction (SX), dispersant (Di) and dynamic extraction (DX) were evaluated as process parameters through a Plackett-Burman design. The maximum extract yield obtained was 7.48 ± 0.15% w/w. The maximum contents of bioactive metabolites in extracts were 0.69 ± 0.09 µg/g of riboflavin, 5.49 ± 0.10 µg/g of α-tocopherol, 524.46 ± 0...
June 12, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28603121/evaluation-of-in-vitro-antidiabetic-and-antioxidant-characterizations-of-elettaria-cardamomum-l-maton-zingiberaceae-piper-cubeba-l-f-piperaceae-and-plumeria-rubra-l-apocynaceae
#15
Afnan Sh Ahmed, Qamaruddin Ahmed, Anil Kumar Saxena, Parveen Jamal
Inhibition of intestinal α-amylase and α-glucosidase is an important strategy to regulate diabetes mellitus (DM). Antioxidants from plants are widely regarded in the prevention of diabetes. Fruits of Elettaria cardamomum (L.) Maton (Zingiberaceae) and Piper cubeba L. f. (Piperaceae) and flowers of Plumeria rubra L. (Apocynaceae) are traditionally used to cure DM in different countries. However, the role of these plants has been grossly under reported and is yet to receive proper scientific evaluation with respect to understand their traditional role in the management of diabetes especially as digestive enzymes inhibitors...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28599245/anti-inflammatory-and-ameliorative-effects-of-gallic-acid-on-fluoxetine-induced-oxidative-stress-and-liver-damage-in-rats
#16
Omid Karimi-Khouzani, Esfandiar Heidarian, Sayed Asadollah Amini
BACKGROUND: Fluoxetine-induced liver damage is a cause of chronic liver disease. In the present study the hepatoprotective effects of gallic acid against fluoxetine-induced liver damage were examined. METHODS: Forty-eight male rats were divided into six groups as follow: group 1, the control group; group 2, rats receiving fluoxetine (24mg/kg bw daily, po) without treatment; group 3, rats receiving 24mg/kg bw fluoxetine, treated with 50mg/kg bw silymarin and groups 4, 5, and 6 in which gallic acid (50, 100, and 200mg/kg bw, po, respectively) was prescribed after the consumption of fluoxetine...
March 23, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28599092/antioxidant-and-proteinase-inhibitory-activities-of-selected-poppy-papaver-somniferum-l-genotypes
#17
Erik Krošlák, Tibor Maliar, Peter Nemeček, Jana Viskupičová, Mária Maliarová, Michaela Havrlentová, Ján Kraic
Poppy seeds (Papaver somniferum L.) belong to tasty food ingredients however, they should be considered also as valuable source of biologically active compounds. Content of selected metabolites, antioxidant and proteinase inhibitory activities were analyzed in vitro in extracts from seeds of fifteen poppy genotypes. Considerable variation in all parameters was detected within the set of analyzed poppy genotypes. The genotype Major expressed the highest antioxidant activity determined by all four methodological approaches (DPPH, ABTS, FRAP, RP)...
June 9, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28593539/the-ahrr-c-565c-g-transversion-may-increase-total-antioxidant-capacity-levels-of-the-seminal-plasma-in-infertile-men
#18
Gholam Ali Josarayi, Azadeh Mohammad-Hasani, Younes Aftabi, Emadodin Moudi, Abasalt Hosseinzadeh Colagar
The Aryl hydrocarbon receptor (AhR)-repressor (AhRR) is a regulator of the AhR pathway, which plays an important role in xenobiotic and reactive oxygen species (ROS) metabolism. Total antioxidant capacity (TAC) is a major factor in semen quality that protects sperm against ROS stress. Malondialdehyde (MDA) is the indicator of lipid peroxidation damage that is occurred due to ROSs. In this study, we determined and compared the MDA and TAC levels of infertile men's semen and blood plasma regarding genotype groups of AhRR-c...
June 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28592113/ph-dependent-lipid-vesicle-interactions-with-plasma-polymerized-thin-films
#19
Hannah J Askew, Mirren Charnley, Karyn L Jarvis, Sally L McArthur
Model lipid vesicle and supported lipid bilayer (SLB) systems are used in a variety of applications including biosensing, cell membrane mimics, and drug delivery. Exposure of a surface to a vesicle solution provides a straightforward method for creating such systems via vesicle adsorption and collapse. However, this process is complex and the relationship between the surface physicochemical properties and vesicle collapse is poorly understood. Plasma polymers are thin conformal films that can be applied to a variety of materials to modify surface properties...
June 7, 2017: Biointerphases
https://www.readbyqxmd.com/read/28587480/nutritional-composition-antioxidant-activity-and-isolation-of-scopoletin-from-senecio-nutans-support-of-ancestral-and-new-uses
#20
Claudio Parra, Emilio Soto, Gloria León, Cristian O Salas, Michael Heinrich, Carlos Echiburú-Chau
Continuing with our study characterising Senecio nutans Sch. Bip., we have isolated and identified a simple coumarin, scopoletin, that could be relevant for the biological properties of the species related with the ancestral medical uses. This is the first report of scopoletin from S. nutans. In addition, the extract was analysed for its antioxidant activity using the ABTS and FRAP method as well as providing the first nutritional analyses of this plant from northern Chile highlands.
June 6, 2017: Natural Product Research
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