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https://www.readbyqxmd.com/read/28220312/preventing-hiv-and-hepatitis-infections-among-people-who-inject-drugs-leveraging-an-indiana-outbreak-response-to-break-the-impasse
#1
EDITORIAL
Jeffrey S Crowley, Gregorio A Millett
Providing clean needles through syringe services programs (SSPs) prevents the spread of disease among people who inject drugs (PWID). The recent HIV outbreak in Scott County, Indiana was a wakeup call with particular significance because modeling suggests that Scott County is but one of many counties in the United States highly vulnerable to an HIV outbreak among PWID. It is a painful recognition that some policy makers ignored the evidence in support of SSPs when it was primarily blacks in inner cities that were affected, yet swung into action in the wake of Scott County where 99% of the cases were white...
February 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28170123/martinello-et%C3%A2-al-hcv-reinfection-incidence-among-individuals-treated-for-recent-infection
#2
Patrick Ingiliz
The development of all-oral direct-acting antiviral agents (DAA) has changed the management of patients infected with the hepatitis C virus (HCV). As these new treatments are safe and highly effective, most affected patients may have a chance for HCV cure, at least in those parts of the world where the costly drugs available. In industrialized countries, HCV infection has a comparatively low prevalence in the general population(1) . A higher prevalence and new infections are mainly seen in two specific subgroups: people who inject drugs (PWID) and HIV-positive men who have sex with men (MSM)...
February 7, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/28160736/patterns-of-harm-reduction-service-utilization-and-hiv-incidence-among-people-who-inject-drugs-in-ukraine-a-two-part-latent-profile-analysis
#3
Danielle C Ompad, Jiayu Wang, Konstantin Dumchev, Julia Barska, Maria Samko, Oleksandr Zeziulin, Tetiana Saliuk, Olga Varetska, Jack DeHovitz
BACKGROUND: Program utilization patterns are described within a large network of harm reduction service providers in Ukraine. The relationship between utilization patterns and HIV incidence is determined among people who inject drugs (PWID) controlling for oblast-level HIV incidence and treatment/syringe coverage. METHODS: Data were extracted from the network's monitoring and evaluation database (January 2011-September 2014, n=327,758 clients). Latent profile analysis was used to determine harm reduction utilization patterns using the number of HIV tests received annually and the number of condoms, syringes, and services (i...
February 1, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28160735/differential-access-to-syringe-exchange-and-other-prevention-activities-among-people-who-inject-drugs-in-rural-and-urban-areas-of-puerto-rico
#4
Melissa Welch-Lazoritz, Patrick Habecker, Kirk Dombrowski, Angelica Rivera Villegas, Carmen Ana Davila, Yadira Rolón Colón, Sandra Miranda De León
BACKGROUND: Injection drug use and its associated blood-borne infections has become a rapidly increasing problem in rural areas of the US recently. Syringe exchange programs have been shown to be effective for reducing transmission of blood borne infections, however access to these prevention efforts may be limited in rural areas. METHODS: This paper utilizes two separate community samples of people who inject drugs (PWID) in Puerto Rico to achieve the following research objectives: (1) compare rural and urban access to syringe exchange programs, free sterile syringes and other HIV/HCV prevention activities, and (2) examine whether utilization of prevention activities is associated with lower injection risk behaviors...
February 1, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28130990/psychiatric-symptoms-quality-of-life-and-hiv-status-among-people-using-opioids-in-saint-petersburg-russia
#5
Alethea Desrosiers, Elena Blokhina, Evgeny Krupitsky, Edwin Zvartau, Richard Schottenfeld, Marek Chawarski
BACKGROUND: The Russian Federation is experiencing a very high rate of HIV infection among people who inject drugs (PWID). However, few studies have explored characteristics of people with co-occurring opioid use disorders and HIV, including psychiatric symptom presentations and how these symptoms might relate to quality of life. The current study therefore explored a.) differences in baseline psychiatric symptoms among HIV+ and HIV- individuals with opioid use disorder seeking naltrexone treatment at two treatment centers in Saint Petersburg, Russia and b...
January 23, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28126684/using-database-linkages-to-monitor-the-continuum-of-care-for-hepatitis-c-virus-among-syringe-exchange-clients-experience-from-a-pilot-intervention
#6
Karli R Hochstatter, Shawnika J Hull, Lauren J Stockman, Laura K Stephens, Heidi K Olson-Streed, William J Ehlenbach, Michael D Repplinger, Elizabeth A Jacobs, Ryan P Westergaard
BACKGROUND: Because many people who inject drugs (PWID) are at high risk of hepatitis C virus (HCV) and have poor access to medical care, many HCV-infected PWID remain undiagnosed and unaccounted for in surveillance systems. Syringe exchange programs (SEPs) are an under-utilized resource for collecting information missing from surveillance systems. Partnerships with public health agencies represent a potentially innovative approach to studying the HCV epidemic for PWID. The goal of this study was to characterize the HCV care continuum for a cohort of PWID using database linkages...
January 23, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28124192/hiv-risk-perception-and-risky-behavior-among-people-who-inject-drugs-in-kermanshah-western-iran
#7
Mehdi Noroozi, Elahe Ahounbar, Salah Eddin Karimi, Sina Ahmadi, Mohammad Najafi, Ali Bazrafshan, Zahra Jorjoran Shushtari, Mohammad Hassan Farhadi, Peter Higgs, Fatemeh Rezaei, Hesam Ghiasvand, Asaad Sharhani, Bahram Armoon, Katherine Waye
PURPOSE: Understanding and increasing awareness on individual risk for HIV infection as well as HIV risk perception's effects on different behavioral outcomes for people who inject drugs (PWID) is important for policymaking and planning purposes. The objectives of the present study were to determine whether HIV risk perception was associated with greater injection and sexual risk-taking behaviors among PWIDs. METHOD: We surveyed 460 PWID in Kermanshah regarding their demographic characteristics, sexual risk behaviors, HIV risk perception, and drug-related risk behaviors in the month prior to the study...
January 25, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28120592/profile-of-people-who-inject-drugs-in-tehran-iran
#8
Masoumeh Amin-Esmaeili, Afarin Rahimi-Movaghar, Maryam Gholamrezaei, Emran Mohammad Razaghi
The marked shift in the patterns of drug use in Iran, from opium smoking to injecting drug use, has led to serious health-related outcomes. This study was designed to explore characteristics of people who inject drugs (PWID) in Tehran, Iran. Nine hundred and four PWID were recruited from treatment and harm reduction facilities, as well as drug user hangouts in public areas in Tehran. Participants were interviewed using the Persian version of the World Health Organization Drug Injecting Study Phase II questionnaire...
December 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/28111221/differential-experiences-of-mexican-policing-by-people-who-inject-drugs-residing-in-tijuana-and-san-diego
#9
Emily F Wood, Dan Werb, Leo Beletsky, Gudelia Rangel, Jazmine Cuevas Mota, Richard S Garfein, Steffanie A Strathdee, Karla D Wagner
BACKGROUND: Research among people who inject drugs (PWIDs) in the USA and Mexico has identified a range of adverse health impacts associated with policing of PWIDs. We employed a mixed methods design to investigate how PWIDs from San Diego and Mexico experienced policing in Tijuana, and how these interactions affect PWIDs behavior, stratifying by country of origin. METHODS: In 2012-2014, 575 PWIDs in San Diego, 102 of whom had used drugs in Mexico in the past six months, were enrolled in the STAHR-II study, with qualitative interviews conducted with a subsample of 20 who had recently injected drugs in Mexico...
January 19, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28107824/implementation-of-methadone-therapy-for-opioid-use-disorder-in-russia-a-modeled-cost-effectiveness-analysis
#10
Bulat Idrisov, Sean M Murphy, Tyler Morrill, Mayada Saadoun, Karsten Lunze, Donald Shepard
BACKGROUND: Opioid agonist therapy using methadone, an effective treatment of opioid use disorders (OUD) for people who inject drugs (PWID), is recommended by the World Health Organization as essential to curtail the growing HIV epidemic. Yet, despite increasing prevalence of OUD and HIV, methadone therapy has not yet been implemented in Russia. The aim of this modeling study was to estimate the cost-effectiveness of methadone therapy for Russian adults with a diagnosed OUD. METHODS/DESIGN: We modeled the projected program implementation costs and estimated disability-adjusted life years (DALYs) averted over a 10-year period, associated with the provision of methadone therapy for a hypothetical, unreplenished cohort of Russian adults with an OUD (n = 249,000), in comparison to the current therapies at existing addiction treatment facilities...
January 20, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28107585/treatment-and-primary-prevention-in-people-who-inject-drugs-for-chronic-hepatitis-c-infection-is-elimination-possible-in-a-high-prevalence-setting
#11
I Gountas, V Sypsa, O Anagnostou, N K Martin, P Vickerman, E Kafetzopoulos, A Hatzakis
AIMS: To project the impact of scaling up oral antiviral therapy and harm reduction on chronic hepatitis C (CHC) prevalence and incidence among people who inject drugs (PWID) in Greece, to estimate the relationship between required treatment levels and expansion of harm reduction programs to achieve specific targets and to examine whether hepatitis C viruse (HCV) elimination among PWID is possible in this high prevalence setting. DESIGN: A dynamic discrete time, stochastic individual-based model was developed to simulate HCV transmission among PWID incorporating the effect of HCV treatment and harm reduction strategies, and allowing for reinfection following treatment...
January 20, 2017: Addiction
https://www.readbyqxmd.com/read/28104570/high-risk-injecting-behaviour-among-people-who-inject-pharmaceutical-opioids-in-australia
#12
Jenny Iversen, George Dertadian, Louise Geddes, Lisa Maher
BACKGROUND: Use of opioid analgesic medicines has doubled globally over the past decade, with a concomitant increase in prevalence of injection of pharmaceutical opioids (PO), including in Australia. This study investigates types of PO injected, methods used to prepare PO for injection and correlates of recent (last 6 months) PO injection among a large national sample of people who inject drugs (PWID). METHODS: The Australian NSP Survey (ANSPS), conducted annually at ∼50 NSP services across Australia, consists of a brief self-administered questionnaire and provision of a capillary dried blood spot for HIV and hepatitis C antibody testing...
January 16, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28104547/residential-eviction-and-exposure-to-violence-among-people-who-inject-drugs-in-vancouver-canada
#13
Mary Clare Kennedy, Ryan McNeil, M-J Milloy, Huiru Dong, Thomas Kerr, Kanna Hayashi
BACKGROUND: People who inject drugs (PWID) experience markedly elevated rates of physical and sexual violence, as well as housing instability. While previous studies have demonstrated an association between homelessness and increased exposure to violence among PWID, the relationship between residential eviction and violence is unknown. We therefore sought to examine the association between residential eviction and experiencing violence among PWID in Vancouver, Canada. METHODS: Data were derived from two open prospective cohort studies of PWID: the Vancouver Injection Drug Users Study (VIDUS) and the AIDS Care Cohort to evaluate Exposure to Survival Services (ACCESS)...
January 16, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28099458/gender-differences-in-factors-related-to-hiv-risk-behaviors-among-people-who-inject-drugs-in-north-east-india
#14
Bushra Sabri, Allison M McFall, Sunil S Solomon, Aylur K Srikrishnan, Canjeevaram K Vasudevan, Santhanam Anand, David D Celentano, Shruti H Mehta, Suresh Kumar, Gregory M Lucas
People who inject drugs (PWID) in India are at high risk for HIV, with women being at elevated risk. Using a socio-ecological framework, this study assessed whether factors associated with HIV transmission risk behaviors differed across men and women PWID. Data for this cross-sectional study were collected from 6449 PWID in 7 cities in Northeast India. Men (n = 5653) and women (n = 796) PWID were recruited using respondent-driven sampling (RDS). We assessed sex differences in two recent HIV transmission risk behaviors: multiple sex partners and needle/syringe sharing...
2017: PloS One
https://www.readbyqxmd.com/read/28097615/trends-in-injection-risk-behaviors-among-people-who-inject-drugs-and-the-impact-of-harm-reduction-programs-in-ukraine-2007-2013
#15
Iuliia Makarenko, D C Ompad, Y Sazonova, T Saliuk, J DeHovitz, L Gensburg
The study examined trends in injection risk behaviors among people who inject drugs (PWIDs) and assessed the impact of harm reduction programs in Ukraine during 2007-2013. We performed a secondary analysis of the data collected in serial cross-sectional bio-behavioral surveillance surveys administered with PWIDs in Ukraine in 2007, 2008, 2011, and 2013. Using data from 14 Ukrainian cities, we assessed short-term trends in injection risk behaviors with the Cochran-Armitage test for trend and multivariable logistic regression models, adjusted for age, sex, region, marital status, education level, occupation, age at injection drug use initiation, experience of overdose, and self-reported HIV status...
January 17, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28090799/national-hiv-care-continua-for-key-populations
#16
Somya Gupta, Reuben Granich
We reviewed published national HIV care continua for men who have sex with men (MSM), people who inject drugs (PWID), and female sex workers (FSWs) to track progress toward the 90-90-90 target. We searched the Internet, PubMed, surveillance reports, United Nations Programme on HIV/AIDS country reports, US President's Emergency Plan for AIDS Relief country/regional operational plans, and conference abstracts for the continua and graded them on quality. We found 12 continua for MSM, 7 for PWID, and 5 for FSW from 12 countries...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28088084/correlates-of-anti-hepatitis-c-positivity-and-use-of-harm-reduction-services-among-people-who-inject-drugs-in-two-cities-in-croatia
#17
Senad Handanagic, Sandra Sevic, Jelena Barbaric, Zoran Dominkovic, Oktavija Dakovic Rode, Josip Begovac, Ivana Bozicevic
BACKGROUND: We assessed correlates of anti-hepatitis C (anti-HCV) positivity and utilization of needle and syringe exchange programs (NSEP) and opioid agonist treatment (OAT) among people who inject drugs (PWID) in two Croatian cities. METHODS: We conducted a cross-sectional study using respondent-driven (RDS) sampling among PWID in Rijeka (N=255) and Split (N=399). We used RDS-weighted population estimates and multivariable logistic regression to explore correlates of anti-HCV positivity and NSEP and OAT utilization...
December 7, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28063072/a-hazard-analysis-of-risk-factors-of-mortality-in-individuals-who-inject-drugs-in-denver-co
#18
Jonathan M Davis, Katie Suleta, Karen F Corsi, Robert E Booth
Despite multiple risk factors for mortality among People Who Inject Drugs (PWID), more research is warranted that examines sub-populations within PWID. Mortality data from PWID participating in longitudinal HIV prevention research in Denver were obtained from The Colorado Department of Public Health and Environment. Risk factors for both all-cause and acute-toxicity related mortality were analyzed using Cox proportional hazards regression. Two-thousand seven individuals were interviewed at baseline. Eighty-six individuals died during the time frame of the study, 58 of which were due to acute-toxicity...
January 6, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/27995679/some-pwid-communities-are-ready-for-prep-so-what-s-next
#19
Julie Bruneau, Élise Roy, Nicolas Demers, Joseph Cox
No abstract text is available yet for this article.
December 20, 2016: Addiction
https://www.readbyqxmd.com/read/27990583/the-role-of-internalized-stigma-in-the-disclosure-of-injecting-drug-use-among-people-who-inject-drugs-and-self-report-as-hiv-positive-in-kohtla-j%C3%A3-rve-estonia
#20
Annika Johannson, Sigrid Vorobjov, Robert Heimer, John F Dovidio, Anneli Uusküla
Disclosure of injecting drug use and its associations with stigma have received very little research attention. This cross-sectional study examined the role of internalized HIV and drug stigma (i.e., self-stigmatization) in the disclosure of injecting drug use among people who inject drugs (PWID) self-reporting as HIV-positive (n = 312) in Kohtla-Järve, Estonia. The internalization of both stigmas was relatively high. On average, PWID disclosed to three disclosure targets out of seven. Disclosure was highest to close friends and health care workers and lowest to employers and casual sex partners...
December 19, 2016: AIDS and Behavior
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