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https://www.readbyqxmd.com/read/28527411/trends-in-reports-of-driving-following-illicit-drug-consumption-among-regular-drug-users-in-australia-2007-2013-has-random-roadside-drug-testing-had-a-deterrent-effect
#1
Danielle Horyniak, Paul Dietze, Simon Lenton, Rosa Alati, Raimondo Bruno, Allison Matthews, Courtney Breen, Lucy Burns
INTRODUCTION: Driving following illicit drug consumption ('drug-driving') is a potential road safety risk. Roadside drug testing (RDT) is conducted across Australia with the dual aims of prosecuting drivers with drugs in their system and deterring drug-driving. We examined trends over time in self-reported past six-month drug-driving among sentinel samples of regular drug users and assessed the impact of experiences of RDT on drug-driving among these participants. METHODS: Data from 1913 people who inject drugs (PWID) and 3140 regular psychostimulant users (RPU) who were first-time participants in a series of repeat cross-sectional sentinel studies conducted in Australian capital cities from 2007 to 2013 and reported driving in the past six months were analysed...
May 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28521829/supervised-injection-facilities-in-canada-past-present-and-future
#2
REVIEW
Thomas Kerr, Sanjana Mitra, Mary Clare Kennedy, Ryan McNeil
Canada has long contended with harms arising from injection drug use. In response to epidemics of HIV infection and overdose in Vancouver in the mid-1990s, a range of actors advocated for the creation of supervised injection facilities (SIFs), and after several unsanctioned SIFs operated briefly and closed, Canada's first sanctioned SIF opened in 2003. However, while a large body of evidence highlights the successes of this SIF in reducing the health and social harms associated with injection drug use, extraordinary efforts were needed to preserve it, and continued activism by local people who inject drugs (PWID) and healthcare providers was needed to promote further innovation and address gaps in SIF service delivery...
May 18, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28521814/access-to-healthcare-insurance-and-healthcare-services-among-syringe-exchange-program-clients-in-massachusetts-qualitative-findings-from-health-navigators-with-the-idu-i-do-care-collaborative
#3
Thomas J Stopka, Marguerite Hutcheson, Ashley Donahue
BACKGROUND: Little is known about access to health insurance among people who inject drugs (PWID) who attend syringe exchange programs (SEPs). The goal of the current study was to assess perceptions of SEP staff, including health navigators and program managers, on access to health insurance and healthcare access among SEP clients following implementation of state and federal policies to enhance universal healthcare access in Massachusetts. METHODS: Between December 2014 and January 2015, we conducted in-depth interviews (n = 14) with SEP staff, including both program managers and health navigators, to assess knowledge, attitudes, and beliefs related to health insurance enrollment and access to enhanced referrals among SEP clients...
May 18, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28520494/racial-ethnic-disparities-at-the-end-of-an-hiv-epidemic-persons-who-inject-drugs-in-new-york-city-2011-2015
#4
Don C Des Jarlais, Kamyar Arasteh, Courtney McKnight, Jonathan Feelemyer, Susan Tross, David Perlman, Samuel Friedman, Aimee Campbell
OBJECTIVES: To examine whether racial/ethnic disparities persist at the "end of the HIV epidemic" (prevalence of untreated HIV infection < 5%; HIV incidence < 0.5 per 100 person-years) among persons who inject drugs (PWID) in New York City. METHODS: We recruited 2404 PWID entering New York City substance use treatment in 2001 to 2005 and 2011 to 2015. We conducted a structured interview, and testing for HIV and herpes simplex virus 2 (HSV-2; a biomarker for high sexual risk)...
May 18, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28515014/hiv-and-the-criminalisation-of-drug-use-among-people-who-inject-drugs-a-systematic-review
#5
Kora DeBeck, Tessa Cheng, Julio S Montaner, Chris Beyrer, Richard Elliott, Susan Sherman, Evan Wood, Stefan Baral
BACKGROUND: Mounting evidence suggests that laws and policies prohibiting illegal drug use could have a central role in shaping health outcomes among people who inject drugs (PWID). To date, no systematic review has characterised the influence of laws and legal frameworks prohibiting drug use on HIV prevention and treatment. METHODS: Consistent with PRISMA guidelines, we did a systematic review of peer-reviewed scientific evidence describing the association between criminalisation of drug use and HIV prevention and treatment-related outcomes among PWID...
May 12, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28514954/needle-exchange-programs-for-the-prevention-of-hepatitis-c-virus-infection-in-people-who-inject-drugs-a-systematic-review-with-meta-analysis
#6
Stephen M Davis, Shay Daily, Alfgeir L Kristjansson, George A Kelley, Keith Zullig, Adam Baus, Danielle Davidov, Melanie Fisher
BACKGROUND: Previous research on the effectiveness of needle exchange programs (NEP) in preventing hepatitis C virus (HCV) in people who inject drugs (PWID) has shown mixed findings. The purpose of this study was to use the meta-analytic approach to examine the association between NEP use and HCV prevention in PWIDs. METHODS: Study inclusion criteria were (1) observational studies, (2) PWIDs, (3) NEP use, (4) HCV status ascertained by serological testing, (5) studies published in any language since January 1, 1989, and (6) data available for measures of association...
May 17, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28511107/frequent-emergency-department-presentations-among-people-who-inject-drugs-a-record-linkage-study
#7
Dhanya Nambiar, Mark Stoové, Paul Dietze
BACKGROUND: People who inject drugs (PWID) have been described as frequent users of health services such as emergency departments (EDs), however few studies have described demographic factors, patterns of substance use and previous health service use associated with frequent use of EDs in this population. METHODS: Using a combination of self-reported data from a cohort of PWID and administrative ED data obtained through record linkage, we identified longitudinal factors associated with the use of ED services...
May 13, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28500290/impact-of-hepatitis-c-treatment-as-prevention-for-people-who-inject-drugs-is-sensitive-to-contact-network-structure
#8
Cornelia Metzig, Julian Surey, Marie Francis, Jim Conneely, Ibrahim Abubakar, Peter J White
Treatment as Prevention (TasP) using directly-acting antivirals has been advocated for Hepatitis C Virus (HCV) in people who inject drugs (PWID), but treatment is expensive and TasP's effectiveness is uncertain. Previous modelling has assumed a homogeneously-mixed population or a static network lacking turnover in the population and injecting partnerships. We developed a transmission-dynamic model on a dynamic network of injecting partnerships using data from survey of injecting behaviour carried out in London, UK...
May 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28496957/injecting-and-sexual-networks-and-sociodemographic-factors-and-dual-hiv-risk-among-people-who-inject-drugs-a-cross-sectional-study-in-kermanshah-province-iran
#9
Mehdi Noroozi, Ali Mirzazadeh, Alireza Noroozi, Hamid Sharifi, Peter Higgs, Zahra Jorjoran-Shushtari, Ali Farhoudian, Farbod Fadai, Farahnaz Mohhamadi-Shahboulaghi, Bahram Armoon, Ahmad Hajebi, Omid Massah
BACKGROUND: Few studies suggest that social network factors, including size of sexual network may associate with drug-related and sexual high-risk behaviors. The objective of this study is to investigate injecting and sexual networks and sociodemographic factors that might be associated with dual HIV risk (DHR) among people who inject drug (PWID). METHODS: The data from a cross-sectional study of 455 PWID that were recruited through peer-referral sampling were used in this study...
July 2016: Addiction & Health
https://www.readbyqxmd.com/read/28494774/expanding-conceptualizations-of-harm-reduction-results-from-a-qualitative-community-based-participatory-research-study-with-people-who-inject-drugs
#10
L M Boucher, Z Marshall, A Martin, K Larose-Hébert, J V Flynn, C Lalonde, D Pineau, J Bigelow, T Rose, R Chase, R Boyd, M Tyndall, C Kendall
BACKGROUND: The perspectives of people who use drugs are critical in understanding why people choose to reduce harm in relation to drug use, what practices are considered or preferred in conceptualizations of harm reduction, and which environmental factors interfere with or support the use of harm reduction strategies. This study explores how people who inject drugs (PWID) think about harm reduction and considers the critical imperative of equity in health and social services delivery for this community...
May 12, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28493917/the-impact-of-hcv-therapy-in-a-high-hiv-hcv-prevalence-population-a-modeling-study-on-people-who-inject-drugs-in-ho-chi-minh-city-vietnam
#11
Ruthie B Birger, Thuy Le, Roger D Kouyos, Bryan T Grenfell, Timothy B Hallett
BACKGROUND: Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) coinfection is a major global health problem especially among people who inject drugs (PWID), with significant clinical implications. Mathematical models have been used to great effect to shape HIV care, but few have been proposed for HIV/HCV. METHODS: We constructed a deterministic compartmental ODE model that incorporated layers for HIV disease progression, HCV disease progression and PWID demography...
2017: PloS One
https://www.readbyqxmd.com/read/28488087/comparison-of-three-popular-methods-for-recruiting-young-persons-who-inject-drugs-for-interventional-studies
#12
Melissa G Collier, Richard S Garfein, Jazmine Cuevas-Mota, Eyasu H Teshale
Persons who inject drugs (PWID) are at risk for adverse health outcomes as a result of their drug use, and the resulting social stigma makes this a difficult population to reach for interventions aimed at reducing morbidity and mortality. During our study of adult PWID aged ≤40 years living in San Diego during 2009 and 2010, we compared three different sampling methods: respondent-driven sampling (RDS), venue-based sampling at one syringe exchange program (SEP), and street-based outreach. We compared demographic, socioeconomic, health, and behavioral factors and tested participants for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) and compared across the three methods...
May 9, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28486075/barriers-to-patient-centered-human-immunodeficiency-virus-hiv-care-with-african-american-patients-who-use-drugs-social-construction-of-the-typical-and-ideal-care-visit
#13
Suzanne Carlberg-Racich, Lindsey Roden
BACKGROUND: A successful patient-provider relationship ensures that patients are treated as individuals and receive appropriate care for their unique circumstances. For this to occur, the relationship needs open communication and trust. African American persons who inject drugs (PWIDs) and who smoke crack cocaine are at elevated risks of poor health outcomes and are often lost to care. In addition, providers often experience difficulty serving this population. Although some barriers are documented in the peer-reviewed literature, this study sought to provide in-depth context to the relationship and how it is constructed...
April 2017: Substance Abuse
https://www.readbyqxmd.com/read/28480230/physician-decisions-to-defer-antiretroviral-therapy-in-key-populations-implications-for-reducing-human-immunodeficiency-virus-incidence-and-mortality-in-malaysia
#14
Enrico G Ferro, Gabriel J Culbert, Jeffrey A Wickersham, Ruthanne Marcus, Alana D Steffen, Heather A Pauls, Ryan P Westergaard, Christopher K Lee, Adeeba Kamarulzaman, Frederick L Altice
BACKGROUND: Antiretroviral therapy (ART) is recommended for all people living with human immunodeficiency virus (HIV), yet physician attitudes and prescribing behaviors toward members of key risk populations may limit ART access and undermine treatment as prevention strategies. METHODS: Physicians in Malaysia (N = 214) who prescribe antiretroviral therapy (ART) responded in an Internet-based survey to hypothetical clinical scenarios of HIV patients, varying by key risk population and CD4(+) T-cell count, on whether they would initiate or defer ART compared with a control patient with sexually acquired HIV...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28476265/undiagnosed-hiv-and-hepatitis-c-infection-in-people-who-inject-drugs-from-new-evidence-to-better-practice
#15
Oleguer Parés-Badell, Albert Espelt, Cinta Folch, Xavier Majó, Victoria González, Jordi Casabona, M Teresa Brugal
BACKGROUND: The objective of this study was to estimate the proportion of undiagnosed HIV or Hepatitis C virus (HCV) infection and to assess the risk factors associated with an undiagnosed infection. METHODS: A questionnaire was distributed among people who inject drugs (PWID) in harm reduction centres in Catalonia, Spain 2008-2012 (n=2243). Self-report of HIV and HCV was compared to oral fluid tests to calculate the proportion of undiagnosed infection. Associations of undiagnosed HIV and HCV with age, origin, risk and protective factors of infection and services use were calculated using a Poisson regression model with robust variance...
June 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28464705/receipt-and-timing-of-hiv-drug-resistance-testing-in-six-u-s-jurisdictions
#16
Sharoda Dasgupta, H Irene Hall, Angela L Hernandez, M Cheryl Bañez Ocfemia, Neeraja Saduvala, Alexandra M Oster
The Department of Health and Human Services recommends drug resistance testing at linkage to HIV care. Because receipt and timing of testing are not well characterized, we examined testing patterns among persons with diagnosed HIV who are linked to care. Using surveillance data in six jurisdictions for persons aged ≥13 years with HIV infection diagnosed in 2013, we assessed the proportion receiving testing, and among these, the proportion receiving testing at linkage. Multivariable log-binomial regression modeling estimated associations between selected characteristics and receipt of testing (1) overall, and (2) at linkage among those tested...
May 3, 2017: AIDS Care
https://www.readbyqxmd.com/read/28448905/drug-use-generations-and-patterns-of-injection-drug-use-birth-cohort-differences-among-people-who-inject-drugs-in-los-angeles-and-san-francisco-california
#17
Ricky N Bluthenthal, Lynn Wenger, Daniel Chu, Philippe Bourgois, Alex H Kral
OBJECTIVES: A robust literature documents generational trends in drug use. We examined the implications of changing national drug use patterns on drug injection histories of diverse people who inject drugs (PWID). METHODS: Drug use histories were collected from 776 active PWID in 2011-13. Using descriptive statistics, we examine drug use initiation by year and birth cohort (BC) differences in drug first injected. A multivariate linear regression model of time to injection initiation ([TTII] (year of first injection minus year of first illicit drug use) was developed to explore BC differences...
April 19, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28432579/hcv-cure-and-reinfection-among-people-with-hiv-hcv-coinfection-and-people-who-inject-drugs
#18
REVIEW
Marianne Martinello, Behzad Hajarizadeh, Jason Grebely, Gregory J Dore, Gail V Matthews
PURPOSE OF REVIEW: Highly effective, well-tolerated interferon-free direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) therapeutics, with the opportunity for broad treatment scale-up among marginalised or "high-risk" populations, including people who inject drugs (PWID) and people with HIV/HCV coinfection. RECENT FINDINGS: Concern that HCV reinfection may compromise HCV treatment outcomes is sometimes cited as a reason for not offering treatment to current and former PWID...
June 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28420917/coping-strategies-mental-health-and-hiv-status-predictors-of-suicidal-behaviour-among-pwids
#19
Bushra Akram, Mubeen Ilyas
OBJECTIVE: To understand suicidal behaviour among people who inject drugs. METHODS: This correlational, cross-sectional study was conducted in two Pakistani cities of Gujrat and Jhelum from October 2015 to March 2016, and comprised male injecting-drug users aged18-60 years. Multistage systematic random sampling method was used. Urdu-translated versions of the brief cope inventory, mental health status scale and suicidal behaviour questionnaire (revised) were administered...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28412292/hla-bw4-80-t-and-multiple-hla-bw4-copies-combined-with-kir3dl1-associate-with-spontaneous-clearance-of-hcv-infection-in-people-who-inject-drugs
#20
Christine Thöns, Tina Senff, Theresa J Hydes, Angela R Manser, Falko M Heinemann, Andreas Heinold, Martin Heilmann, Arthur Y Kim, Markus Uhrberg, Norbert Scherbaum, Georg M Lauer, Salim I Khakoo, Jörg Timm
BACKGROUND AND AIMS: NK cell function is regulated by inhibitory and activating receptors including killer-cell immunoglobulin-like receptors (KIRs). Here, we analyzed the impact of different KIR/KIR-ligand genotypes on the outcome of HCV infection in people who inject drugs (PWID). KIR/KIR-ligand genotypes associated with spontaneous clearance of HCV infection were identified in a cohort of PWID from Germany (n=266) and further validated in a second anti-HCV positive cohort of PWID recruited in North America (n=342)...
April 12, 2017: Journal of Hepatology
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