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syndrome Pickwick

Jaime Corral, Maria Victoria Mogollon, M-Ángeles Sánchez-Quiroga, Javier Gómez de Terreros, Auxiliadora Romero, Candela Caballero, Joaquin Teran-Santos, María L Alonso-Álvarez, Teresa Gómez-García, Mónica González, Soledad López-Martínez, Pilar de Lucas, José M Marin, Odile Romero, Trinidad Díaz-Cambriles, Eusebi Chiner, Carlos Egea, Roberto M Lang, Babak Mokhlesi, Juan F Masa
RATIONALE: Despite a significant association between obesity hypoventilation syndrome (OHS) and cardiac dysfunction, no randomised trials have assessed the impact of non-invasive ventilation (NIV) or CPAP on cardiac structure and function assessed by echocardiography. OBJECTIVES: We performed a secondary analysis of the data from the largest multicentre randomised controlled trial of OHS (Pickwick project, n=221) to determine the comparative efficacy of 2 months of NIV (n=71), CPAP (n=80) and lifestyle modification (control group, n=70) on structural and functional echocardiographic changes...
April 2018: Thorax
Claude-Henri Chouard
CONCLUSION: If Napoleon had been treated, Europa would then have doubtless been different, and perhaps would not have known the last two World wars. OBJECTIVES: This study plans to demonstrate that Napoleon very probably suffered from Chronic Rhonchopathy. BACKGROUND: Between 1983-1993, the author led their ENT department of CHU Saint-Antoine to contribute in the knowledge of chronic snoring and Obstructive Sleep Apneas Syndrome (OSAS), and to define the treatment of their consequences...
April 2017: Acta Oto-laryngologica
María José López-Jiménez, Juan F Masa, Jaime Corral, Joaquín Terán, Estrella Ordaz, Maria F Troncoso, Nicolás González-Mangado, Mónica González, Soledad Lopez-Martínez, Pilar De Lucas, José M Marín, Sergi Martí, Trinidad Díaz-Cambriles, Josefa Díaz-de-Atauri, Eusebi Chiner, Felipe Aizpuru, Carlos Egea, Auxiliadora Romero, José M Benítez, Jesús Sánchez-Gómez, Rafael Golpe, Ana Santiago-Recuerda, Silvia Gómez, Ferrán Barbe, Mónica Bengoa
The Pickwick project was a prospective, randomized and controlled study, which addressed the issue of obesity hypoventilation syndrome (OHS), a growing problem in developed countries. OHS patients were divided according to apnea-hypopnea index (AHI) ≥30 and <30 determined by polysomnography. The group with AHI≥30 was randomized to intervention with lifestyle changes, noninvasive ventilation (NIV) or continuous positive airway pressure (CPAP); the group with AHI<30 received NIV or lifestyle changes...
March 2016: Archivos de Bronconeumología
Juan F Masa, Jaime Corral, Maria L Alonso, Estrella Ordax, Maria F Troncoso, Monica Gonzalez, Soledad Lopez-Martínez, Jose M Marin, Sergi Marti, Trinidad Díaz-Cambriles, Eusebi Chiner, Felipe Aizpuru, Carlos Egea
RATIONALE: The incidence of obesity hypoventilation syndrome (OHS) may be increasing in parallel with the present obesity epidemic. Despite extensive noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) use in patients with OHS, information regarding efficacy is limited. OBJECTIVES: We performed a large, multicenter randomized controlled study to determine the comparative efficacy of NIV, CPAP, and lifestyle modification (control group) using daytime PaCO2 as the main outcome measure...
July 1, 2015: American Journal of Respiratory and Critical Care Medicine
Ahmed Abdelghani, Halima Ben Salem
No abstract text is available yet for this article.
January 2014: La Tunisie Médicale
Meir Kryger
In 1836 Charles Dickens published the first installment of The Posthumous Papers of the Pickwick Club. In this novel he introduces the reader to a character, Joe, the Fat Boy who is obese, sleepy, difficult to arouse, snores, and has peripheral edema. This description so intrigued the medical field that many hypotheses about the symptoms were examined, but it was not until 120 years after the novel was published that physicians started to interrelate these features and a new field of medicine emerged. Although he is best known for this description, Dickens impacted medicine and medical care in many ways...
June 15, 2012: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Anda Popescu, Roxana Roşu, Florin Mihălţan
Described in the specialty literature for over one century under the name of Pickwick syndrome, the obesity--hypoventilation syndrome (OHS) includes the triad: obesity--hypoventilation--hypersomnia. In Romania, this entity is rarely recognized and, despite the developments in specific investigations, the disease is frequently difficult to differentiate from other respiratory disorders during sleep. The authors try to clarify some issues related to pathophysiologic mechanism and contribution of mechanical factors or of respiratory nervous center etc...
October 2006: Pneumologia: Revista Societății Române de Pneumologie
Pier Luigi Giorgi
Obese adolescents are prone to several pathologies, which may begin in this period of life and have a continuity in adult age. In this review the author tries first to explain the obesity definition in infants, children, and adolescents. Some pathologies may appear in adolescent age. First of all, some features of the so called metabolic syndrome; furthermore, hormonal alteration during and after puberty, genital appearance in the obese adolescent male, respiratory problems as apnea, asthma, and the Pickwick syndrome...
February 2007: Recenti Progressi in Medicina
Antoine Cuvelier, Jean-François Muir
No abstract text is available yet for this article.
January 2007: Chest
Andrea A Conti, Antonio Conti, Gian Franco Gensini
The obstructive sleep apnea syndrome (OSAS) is a clinical condition characterized by the coexistence of irregular breathing at night with excessive daytime sleepiness, and it represents a major social health issue because of its high prevalence and of the growing public awareness of it. The XIX century description of "Fat Joe", the famous character of Charles Dickens's Pickwick Papers, is often retained the first presentation of a person affected by OSAS, since Joe was an obese individual who fell asleep during daytime while performing even extremely simple tasks...
2006: Medical Hypotheses
(no author information available yet)
No abstract text is available yet for this article.
November 1960: Actualidad Pediátrica; Revista de Bibliografía Internacional
No abstract text is available yet for this article.
November 30, 1959: Polski Tygodnik Lekarski
No abstract text is available yet for this article.
December 1964: Wiener Zeitschrift Für Innere Medizin und Ihre Grenzgebiete
No abstract text is available yet for this article.
May 1965: Il Fracastoro
No abstract text is available yet for this article.
November 1964: Helvetica Medica Acta
No abstract text is available yet for this article.
April 23, 1965: Wiener Klinische Wochenschrift
No abstract text is available yet for this article.
May 29, 1965: La Presse Médicale
No abstract text is available yet for this article.
January 1965: Annales Médicales de Nancy
No abstract text is available yet for this article.
September 21, 1964: Polski Tygodnik Lekarski
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