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Bryan R Haugen, Anna M Sawka, Erik K Alexander, Keith C Bible, Patrizio Caturegli, Gerard M Doherty, Susan J Mandel, John C Morris, Aziza Nassar, Furio Pacini, Martin Schlumberger, Kathryn Schuff, Steven I Sherman, Hilary Somerset, Julie Ann Sosa, David L Steward, Leonard Wartofsky, Michelle D Williams
American Thyroid Association (ATA) leadership asked the ATA Thyroid Nodules and Differentiated Thyroid Cancer Guidelines Task Force to review, comment on, and make recommendations related to the suggested new classification of encapsulated follicular variant papillary thyroid carcinoma (eFVPTC) without capsular or vascular invasion to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). The task force consists of members from the 2015 guidelines task force with the recusal of three members who were authors on the paper under review...
April 2017: Thyroid: Official Journal of the American Thyroid Association
Rosie Earle, Enda Shanahan, Himat Vaghadia, Andrew Sawka, Raymond Tang
PURPOSE: Nasotracheal intubation is a widely performed technique to facilitate anesthesia induction during oral, dental, and maxillofacial surgeries. The technique poses several risks not encountered with oropharyngeal intubation, most commonly epistaxis due to nasal mucosal abrasion. The purpose of this study was to test whether the use of the Parker Flex-Tip™ (PFT) nasal endotracheal tube (ETT) with a posterior facing bevel reduces epistaxis when compared with the standard nasal RAE ETT with a leftward facing bevel...
April 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
Beth A Beidleman, Janet E Staab, Stephen R Muza, Michael N Sawka
Despite decades of research, the magnitude and time course of hematologic and plasma volume (PV) changes following rapid ascent and acclimation to various altitudes are not precisely described. To develop a quantitative model, we utilized a comprehensive database and general linear mixed models to analyze 1055 hemoglobin ([Hb]) and hematocrit (Hct) measurements collected at sea level and repeated time points at various altitudes in 393 unacclimatized men (n=270) and women (n=123) who spent between 2 hours and 7 days at 2500-4500 m under well-controlled experimental conditions...
December 30, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Sinan Hersek, Hakan Toreyin, Caitlin N Teague, Mindy L Millard-Stafford, Hyeon-Ki Jeong, Miheer M Bavare, Paul Wolkoff, Michael N Sawka, Omer T Inan
We designed and validated a portable electrical bioimpedance (EBI) system to quantify knee joint health. METHODS: Five separate experiments were performed to demonstrate the: (1) ability of the EBI system to assess knee injury and recovery; (2) inter-day variability of knee EBI measurements; (3) sensitivity of the system to small changes in interstitial fluid volume; (4) reducing the error of EBI measurements using acceleration signals; (5) use of the system with dry electrodes integrated to a wearable knee wrap...
December 22, 2016: IEEE Transactions on Bio-medical Engineering
June C Carroll, Tutsirai Makuwaza, Donna P Manca, Nicolette Sopcak, Joanne A Permaul, Mary Ann O'Brien, Ruth Heisey, Elizabeth A Eisenhauer, Julie Easley, Monika K Krzyzanowska, Baukje Miedema, Sandhya Pruthi, Carol Sawka, Nancy Schneider, Jonathan Sussman, Robin Urquhart, Catarina Versaevel, Eva Grunfeld
OBJECTIVE: To assess primary care providers' (PCPs') experiences with, perceptions of, and desired role in personalized medicine, with a focus on cancer. DESIGN: Qualitative study involving focus groups. SETTING: Urban and rural interprofessional primary care team practices in Alberta and Ontario. PARTICIPANTS: Fifty-one PCPs. METHODS: Semistructured focus groups were conducted and audiorecorded...
October 2016: Canadian Family Physician Médecin de Famille Canadien
Rosie Earle, Himat Vaghadia, Enda Shanahan, Raymond Tang, Andrew Sawka
We report the novel application of photoplethysmographic technology with the Nexfin HD monitor for real-time measurement of blood pressure (BP) in a patient with tetraamelia. The patient was a 58-year-old man with tetraamelia secondary to thalidomide exposure in utero, who presented for surgical excision of a maxillary schwannoma. Because difficulty of cuff use on rudimentary limbs and failure to gain invasive arterial access due to abnormalities of limb vasculature, this population is known to pose some unique challenges for BP measurement...
November 2016: Journal of Clinical Anesthesia
Patrick Brown, Hedy Jiang, Shereen Ezzat, Anna M Sawka
BACKGROUND: Thyroid cancer has been rapidly rising in incidence in Canada; however, in contrast, lung cancer appears to be decreasing in incidence in Canadian men and stable in women. Moreover, disease-related mortality risk is generally very low in TC but high in LC. We performed a geographic spatial analysis in metropolitan Toronto, Canada to determine if there is regional variability of respective risks of thyroid cancer (TC) and lung cancer (LC), among women. Women were of particular interest for this study, given their known predilection for thyroid cancer...
2016: BMC Public Health
Matthew T Wittbrodt, J C Mizelle, Lewis A Wheaton, Michael N Sawka, Mindy L Millard-Stafford
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Yong Gyu Hyun, Ahmad Alhashemi, Rouhi Fazelzad, Alyse S Goldberg, David P Goldstein, Anna M Sawka
BACKGROUND: Patient education and psychosocial support to patients are important elements of comprehensive cancer care, but the needs of thyroid cancer survivors are not well understood. METHODS: The published English-language quantitative literature on (i) unmet medical information and (ii) psychosocial support needs of thyroid cancer survivors was systematically reviewed. A librarian information specialist searched seven electronic databases and a hand search was conducted...
September 2016: Thyroid: Official Journal of the American Thyroid Association
John W Castellani, Edward J Zambraski, Michael N Sawka, Maria L Urso
Hyperthermia is suspected of accentuating skeletal muscle injury from novel exercise, but this has not been well studied. This study examined if high muscle temperatures alters skeletal muscle injury induced by eccentric exercise (ECC). Eight volunteers (age, 22.5 ± 4.1 year; height, 169.5 ± 10.8 cm; body mass, 76.2 ± 12.6 kg), serving as their own control, and who were not heat acclimatized, completed two elbow flexor ECC trials; in one trial the biceps were heated >40°C (HEAT) and in the other trial there was no heating (NON)...
May 2016: Physiological Reports
Anna M Sawka, Richard W Tsang, James D Brierley, Lorne Rotstein, Phillip Segal, Shereen Ezzat, David P Goldstein
No abstract text is available yet for this article.
September 2016: Acta Oncologica
Anna M Sawka, Shereen Ezzat, Patrick E Brown
No abstract text is available yet for this article.
May 2016: Endocrine Practice
Anna M Sawka, Shereen Ezzat, David P Goldstein
No abstract text is available yet for this article.
April 2016: Endocrine Practice
Caitlin N Teague, Sinan Hersek, Hakan Toreyin, Mindy L Millard-Stafford, Michael L Jones, Geza F Kogler, Michael N Sawka, Omer T Inan
OBJECTIVE: We present the framework for wearable joint rehabilitation assessment following musculoskeletal injury. We propose a multimodal sensing (i.e., contact based and airborne measurement of joint acoustic emission) system for at-home monitoring. METHODS: We used three types of microphones-electret, MEMS, and piezoelectric film microphones-to obtain joint sounds in healthy collegiate athletes during unloaded flexion/extension, and we evaluated the robustness of each microphone's measurements via: 1) signal quality and 2) within-day consistency...
August 2016: IEEE Transactions on Bio-medical Engineering
Julien D Périard, Gavin J S Travers, Sébastien Racinais, Michael N Sawka
This review examines the cardiovascular adaptations along with total body water and plasma volume adjustments that occur in parallel with improved heat loss responses during exercise-heat acclimation. The cardiovascular system is well recognized as an important contributor to exercise-heat acclimation that acts to minimize physiological strain, reduce the risk of serious heat illness and better sustain exercise capacity. The upright posture adopted by humans during most physical activities and the large skin surface area contribute to the circulatory and blood pressure regulation challenge of simultaneously supporting skeletal muscle blood flow and dissipating heat via increased skin blood flow and sweat secretion during exercise-heat stress...
April 2016: Autonomic Neuroscience: Basic & Clinical
Jacques Smit, Raymond Tang, Himat Vaghadia, Andrew Sawka
No abstract text is available yet for this article.
March 2016: Regional Anesthesia and Pain Medicine
I Mowat, R Tang, H Vaghadia, C Krebs, W R Henderson, A Sawka
BACKGROUND: Local anaesthetics are commonly delivered to the epidural space by either intermittent bolus or continuous infusion. While these methods have been investigated in terms of analgesia and total dose administered, they have not been compared in terms of their effect on the spread of injectate within the epidural space. This animal study compared the spread of dye delivered to the epidural space in a porcine model by either bolus or infusion. METHODS: After ethical approval, epidural catheters were placed at three vertebral levels in seven anaesthetized pigs...
February 2016: British Journal of Anaesthesia
Rachel J Jolley, Hude Quan, Nathalie Jetté, Keri Jo Sawka, Lucy Diep, Jade Goliath, Derek J Roberts, Bryan G Yipp, Christopher J Doig
OBJECTIVE: Administrative health data are important for health services and outcomes research. We optimised and validated in intensive care unit (ICU) patients an International Classification of Disease (ICD)-coded case definition for sepsis, and compared this with an existing definition. We also assessed the definition's performance in non-ICU (ward) patients. SETTING AND PARTICIPANTS: All adults (aged ≥ 18 years) admitted to a multisystem ICU with general medicosurgical ICU care from one of three tertiary care centres in the Calgary region in Alberta, Canada, between 1 January 2009 and 31 December 2012 were included...
2015: BMJ Open
Anna M Sawka, James D Brierley, Richard W Tsang, Lorne Rotstein, Shereen Ezzat, David P Goldstein
No abstract text is available yet for this article.
March 2016: Thyroid: Official Journal of the American Thyroid Association
Ahmad Alhashemi, David P Goldstein, Anna M Sawka
PURPOSE OF REVIEW: Active surveillance is close follow-up of neoplasms, with predetermined intervention triggers. We systematically reviewed the published English language literature on primary active surveillance of low-risk papillary thyroid cancer (PTC). RECENT FINDINGS: We searched seven electronic databases (1980-2015), supplemented with a hand search. Two reviewers independently screened 1715 citations and reviewed 32 full-text papers, ultimately including two papers...
January 2016: Current Opinion in Oncology
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