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https://www.readbyqxmd.com/read/29783248/-features-of-the-course-of-irritable-bowel-syndrome-in-patients-with-excess-body-weight
#1
Mykola A Bychkov, Iryna M Ferents
OBJECTIVE: Introduction: Currently, the diagnosis of irritable bowel syndrome (IBS) is only based on clinical symptoms without clear interpretation and can be interpreted differently, complicating the diagnosis. Therefore, to study features of the prevalence and the course of IBS in patients with excessive body weight / obesity is of particular significance nowadays. The aim of the research is to evaluate the prevalence and the course of IBS in patients with obesity. PATIENTS AND METHODS: Materials and methods: Observation results for 120 obese persons who underwent in-patient treatment at various hospital departments in Western Ukraine have been analyzed to evaluate the prevalence of IBS...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783219/-clinical-and-laboratory-features-of-cholelithiasis-in-patients-with-type-2-diabetes-by-gender
#2
Natalya I Dyakiv-Koreiba
OBJECTIVE: Introduction: Today, diabetes is considered a factor that provokes the development of bile duct disease. Cholelithiasis is associated with such risk factors as aging, high body mass index, female sex, genetic predisposition, alcohol abuse, high concentration of triglycerides and cholesterol, low density lipoprotein in blood plasma The aim of the work is to analyze the clinical and laboratory features of the pathology of the gall bladder in patients with type 2 diabetes, depending on the sex...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782983/an-in-vivo-biocompatibility-study-of-surgical-meshes-made-from-bacterial-cellulose-modified-with-chitosan
#3
Joanna Piasecka-Zelga, Piotr Zelga, Joanna Szulc, Justyna Wietecha, Danuta Ciechańska
Bacterial cellulose modified with chitosan (MBC) is an innovative biomaterial used in regenerative medicine which may potentially improve treatment outcomes mesh for hernia repair surgery by facilitating better absorption in native tissue with less risk of mesh-related infections. The aim of the present study was to evaluate the biocompatibility of mesh based on MBC, and determine whether immunological reactions occur due to hypersensitivity to the implants. Forty five Imp:WIST rats were randomly assigned to be implanted with one of three mesh types: simple polypropylene mesh (n = 15), mesh modified by bacterial cellulose only (n = 15) and MBC mesh (n = 15) and evaluated after one and three months following intramuscular implantation...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29782469/effectiveness-of-probiotics-in-children-with-functional-abdominal-pain-disorders-and-functional-constipation-a-systematic-review
#4
Carrie A M Wegh, Marc A Benninga, Merit M Tabbers
OBJECTIVE: The objective of this study was to investigate the effect of probiotics on functional abdominal pain disorders (FAPD) and functional constipation (FC). METHODS: A systematic review was conducted, searching PubMed and Cochrane databases from inception to January 2018 for randomized controlled trials (RCTs) investigating the efficacy of probiotics in children aged 4 to 18 years with FAPD or children aged 0 to 18 years with FC. RESULTS: A total of 657 citations were identified...
May 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#5
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782297/treatment-of-scabies-and-pediculosis-in-health-education-publications-and-folk-medicine-of-eastern-croatia-slavonija-baranja-and-western-srijem-county
#6
Ivanka Muršić, Igor Kuric, Marija Raguž, Tatjana Kovačević, Dora Muršić
Scabies and pediculosis are common parasitic infestations of the skin and hair, manifesting with intense pruritus and effectively treated with modern medications. Because of the attached social stigma linking it with poverty and poor hygiene, patients will often attempt alternative folk-based remedies before confiding in their physicians. We conducted a comprehensive bibliographical study of historic folk literature and interviewed 70 individuals experienced in everyday application of folk medicine in order to categorize available remedies and provide a modern, scientific comment on their effectiveness and dangers...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781718/comparsion-of-staining-characteristics-of-toto-bodies
#7
S S Padala, M A Kiresur, A Ananthaneni, V S Guduru, H K Puneeth, B Bhavana
Toto bodies are eosinophilic structures that resemble the cells of the superficial cell layer of the oral epithelium. Toto bodies commonly are associated with inflammatory gingival and other mucosal lesions including pyogenic granuloma, irritational fibroma, epulis fissuratum, peripheral giant cell granuloma and inflammatory hyperplastic gingivitis. We evaluated staining characteristics of Toto bodies to establish their origin and to identify their significance in lesions. We investigated pyogenic granuloma, fibroma and leukoplakia with epithelium that exhibited Toto bodies after hematoxylin and eosin (staining...
May 21, 2018: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/29781584/erythema-ab-igne
#8
Isabelle Marie
A 41 year-old woman was diagnosed as having limited cutaneous systemic sclerosis (SSc) in March 2012. The cutaneous impairment of SSc was characterized by sclerodactyly associated with pitting scars; systemic manifestations of SSc included esophageal involvement, with both absence of peristalsis in the lower two-thirds of the oesophageal body and low pressure in the lower oesophageal sphincter. In 2017, the patient presented with livedo reticularis lesions of her abdomen (Panel A) evolving for one month. The patient denied pruritus, pain, or exposure of abdomen to irritants prior to lesion onset...
May 21, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29781381/associations-between-daytime-sleepiness-psychological-symptoms-headache-and-abdominal-pain-in-schoolchildren
#9
Marja-Liisa Gustafsson, Camilla Laaksonen, Sanna Salanterä, Eliisa Löyttyniemi, Minna Aromaa
Daytime sleepiness and different symptoms are common problems affecting health and well-being of schoolchildren. This population-based cohort study included 568 children who were followed from ages 10 to 15 years. Daytime sleepiness, headache, abdominal pain, and psychological symptoms (depression, irritability or bad temper, nervousness, anxiety, and dejection) were assessed by self-administered questionnaires. The prevalence of frequent daytime sleepiness was 13% at the ages of 10 and 12 years and increased significantly up to 24% at the age of 15 ( p < ...
January 1, 2018: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/29780794/pediatric-scurvy-when-contemporary-eating-habits-bring-back-the-past
#10
Alice Brambilla, Cristina Pizza, Donatella Lasagni, Lucia Lachina, Massimo Resti, Sandra Trapani
Vitamin C deficiency is anecdotal in developed countries, mainly associated with underling clinical morbidities as autism or neurological impairment. Chronic insufficient dietary supply is responsible for vascular fragility and impaired bone formation, resulting in gingival bleeding, petechial lesions, articular and bone pain or limb swelling. Children may present anorexia, irritability, failure to thrive, limping or refusal to walk. Accordingly, pediatric scurvy is frequently misdiagnosed with osteomyelitis, septic arthritis, bone and soft tissue tumor, leukemia, bleeding disorders, and rheumatologic conditions...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29780412/a-prediction-model-for-recognizing-strangulated-small-bowel-obstruction
#11
Xiaming Huang, Guan Fang, Jie Lin, Keyu Xu, Hongqi Shi, Lei Zhuang
Introduction: Early and accurate diagnosis of strangulated small bowel obstruction (SSBO) is difficult. This study aimed to devise a prediction model for predicting the risk of SSBO. Materials and Methods: A database of 417 patients who had clinical symptoms of intestinal obstruction confirmed by computed tomography (CT) were evaluated for inclusion in this study. Symptoms and laboratory and radiologic findings of these patients were collected after admission. These clinical factors were analyzed using logistic regression...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29779407/association-of-irritable-bowel-syndrome-and-venous-thromboembolism-methodological-and-statistical-issues
#12
Xiaoyan Liu, Kui Liu
No abstract text is available yet for this article.
May 20, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29778883/hyaluronic-acid-modified-lipid-polymer-hybrid-nanoparticles-as-an-efficient-ocular-delivery-platform-for-moxifloxacin-hydrochloride
#13
Dan Liu, Yunfei Lian, Qiuyu Fang, Lu Liu, Jundong Zhang, Juan Li
To improve the ocular bioavailability of the strongly hydrophilic moxifloxacin hydrochloride, hyaluronic-acid-modified lipid-polymer hybrid nanoparticles (HA-LCS-NPs) were designed and characterized. An in vivo precorneal retention study in rabbits showed that the mean residence time (MRT) and area under the curve (AUC0-6h ) of HA-LCS-NPs were up to 6.74-fold and 4.29-fold higher than those of the commercial product. An in vitro corneal penetration study in rabbits demonstrated that the apparent permeability coefficient (Papp) of HA-LCS-NPs was increased by 3...
May 17, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29778747/novel-peptide-inhibits-inflammation-by-suppressing-of-protease-activated-receptor-2
#14
Bora Kim, Hyun-Soo Kim
We synthesized and investigated the effects of a novel peptide B, RRFSLLRY as a novel PAR-2 antagonist. Peptide B decreased calcium levels in HaCat cells stimulated with trypsin and PAR-2 activator (SLIGKV) and cytokeratin 14 and PCNA was decreased by peptide B. Peptides B also reduced the expression of inflammatory cytokines such as TNF-α and interleukin-6. Significant increase of oxazolone-induced transepidermal water loss (TEWL) was decreased by the addition of peptide B in hairless mice. These findings suggest that the anti-inflammatory effect of peptide B is due to inhibition of PAR-2 signaling...
May 17, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29777856/ocular-irritation-and-cyclosporine-a-distribution-in-the-eye-tissues-after-administration-of-solid-lipid-microparticles-in-the-rabbit-model
#15
Eliza Wolska, Małgorzata Sznitowska, Juliusz Chorążewicz, Oliwia Szerkus, Aleksandra Radwańska, Michał J Markuszewski, Roman Kaliszan, Krystyna Raczyńska
The aim of this study was to investigate the in vivo effect of Solid Lipid Microparticles (SLM), proposed for topical ocular administration of cyclosporine, on the rabbit eye. SLM carrier is an aqueous dispersion of lipid microparticles (20% w/w) with a size up to 15 μm. Cyclosporine was dissolved in the formulation in the concentration of 0.5 or 2.0% (w/w). Ocular tolerance of microsphere dispersion was assessed in rabbit model by the Draize eye test (SLM was compared with emulsion and oily solution), and cyclosporine distribution in ocular tissues was evaluated after multiple application of tested formulations (SLM dispersions, emulsions and oily solution) for 7 days...
May 16, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29777439/fecal-and-mucosa-associated-intestinal-microbiota-in-patients-with-diarrhea-predominant-irritable-bowel-syndrome
#16
Nitsan Maharshak, Yehuda Ringel, David Katibian, Ashley Lundqvist, R Balfour Sartor, Ian M Carroll, Tamar Ringel-Kulka
BACKGROUND: Irritable bowel syndrome (IBS) has been associated with changes in the intestinal microbiota. Only a few studies have explored differences in the mucosa-associated microbiota between IBS patients and healthy controls (HC). AIMS: To characterize and compare the microbiota in mucosal and fecal samples from carefully selected patients with IBS-D and HC. METHODS: The cohort was composed of 23 diarrhea-predominant IBS (IBS-D) patients and 24 HC...
May 17, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29776761/-pterygium-surgery-by-conjunctiva-autograft-with-autologous-blood-fixation
#17
C G F Nganga Ngabou, C Makita, S S Ndalla, F Nkokolo, R Messe Ambia Koulimaya, B Diatewa
INTRODUCTION: Pterygium surgery is marked by the possibility of recurrences; one of the techniques which results in the least recurrences is conjunctival autograft. Fixation of the conjunctiva had traditionally been accomplished with sutures. In recent years, conjunctival grafting has also been performed with fibrin glue. Even more recently, with a view towards improving the quality of postoperative results, some surgeons recommend the use of autologous blood. This study aims to evaluate the stability of this latest method of graft fixation, while assessing its postoperative results...
May 15, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29776480/concussion-symptom-prevalence-severity-and-trajectory-implications-for-nursing-practice
#18
Gail Macartney, Valérie Simoncic, Kristian Goulet, Mary Aglipay
PURPOSE: The purpose of this study was to describe the symptom severity and trajectory in concussed children who were followed during a one year period at a concussion clinic. DESIGN AND METHODS: A retrospective chart review was completed to describe the symptom trajectory up to three months during the recovery. RESULTS: One hundred and thirty-six patients were included (74 female, 62 male) with a median age of 15.4years (range 13-17). The most common mechanisms of injury included: falls (19...
May 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29776398/primary-bacterial-ventriculitis-in-adults-an-emergent-diagnosis-challenge-report-of-a-meningoccal-case-and-review-of-the-literature
#19
Anaïs Lesourd, Nicolas Magne, Anaïs Soares, Caroline Lemaitre, Muhamed-Kheir Taha, Isabelle Gueit, Michel Wolff, François Caron
BACKGROUND: Defined by an infection of the ventricular system of the brain, ventriculitis is usually known as a health-care associated infection. In contrast, primary pyogenic ventriculitis complicating community-acquired meningitis is uncommon, and mainly described in infants. Only seven cases that have occured in adults have been found in the international literature. CASE PRESENTATION: We report here a new case due to Neisseria meningitidis occurring in an 85 year-old-man...
May 18, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29775769/quality-of-life-after-combined-endonasal-endoscopic-odontoidectomy-and-posterior-suboccipital-decompression-and-fusion
#20
Malte Ottenhausen, Andrew F Alalade, Kavelin Rumalla, Prakash Nair, Ali Baaj, Roger Hartl, Ashutosh Kacker, Jeffrey P Greenfield, Vijay K Anand, Theodore H Schwartz
INTRODUCTION: Basilar invagination can result from a variety of systemic diseases that can weaken the structural integrity of the craniocervical junction. Definitive treatment often requires ventral decompression along with posterior decompression and fusion. Endonasal odontoidectomy is a relatively new minimal access procedure, however, quality of life after this procedure has not been reported. METHODS: We reviewed a consecutive database of endonasal odontoidectomy patients and identified those having posterior decompression and fusion...
May 15, 2018: World Neurosurgery
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