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P Aguilera, Y Gilaberte, A Pérez-Ferriols, D de Argila, J Aguilera, M V de Galvez, M T Granados, J Gardeazabal, J M Carrascosa
No abstract text is available yet for this article.
July 14, 2020: Actas Dermo-sifiliográficas
#22
MULTICENTER STUDY
Andreu Fernández-Codina, Blanca Pinilla, Iago Pinal-Fernández, Iago Carballo, Carlos Feijoo-Massó, María Toledano-Macías, Borja de Miguel-Campo, Eva Fonseca-Aizpuru, Luis Sáez-Comet, Miguel López-Dupla, José Hernández-Rodríguez, Fernando Martínez-Valle
OBJECTIVES: Several IgG4-related disease (IgG4-RD) phenotypes have been proposed and the first set of classification criteria have been recently created. Our objectives were to assess the phenotype distribution and the performance of the classification criteria in Spanish patients as genetic and geographical differences may exist. METHODS: We performed a cross-sectional multicentre study (Registro Español de Enfermedad Relacionada con la IgG4, REERIGG4) with nine participating centres from Spain...
January 5, 2021: Rheumatology
#23
JOURNAL ARTICLE
Jesús López-Herce, Ignacio Manrique, Angel Carrillo, Custodio Calvo, Sara Pons, Gema Manrique
No abstract text is available yet for this article.
March 2021: Anales de pediatría
#24
Jesús López-Herce, Ignacio Manrique, Ángel Carrillo, Custodio Calvo, Gema Manrique
No abstract text is available yet for this article.
July 6, 2020: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
#25
J M Carrascosa, M A Pastor-Nieto, I Ruiz-González, J F Silvestre, L Borrego, M E Gatica-Ortega, A M Giménez-Arnau
As the COVID-19 pandemic gradually comes under control, the members of the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) have drawn up a proposed list of the requirements, limitations, and conditioning factors affecting the resumption of work in contact dermatitis units. The assumption is that the severe acute respiratory syndrome coronavirus2 is still circulating and that occasional or seasonal outbreaks will occur. They recommend that the first step should be to assess how many patch tests each clinic can handle and review the waiting list to prioritize cases according to disease severity and urgency...
October 2020: Actas dermo-sifiliográficas
#26
MULTICENTER STUDY
T Fernandez Aparicio, J A Galan Llopis, R Cansino Alcaide, D Pérez Fentes, M Cepeda Delgado, J L Alvarez-Ossorio
INTRODUCTION AND OBJECTIVES: The incidence of upper urinary tract tumors is currently unknown. The aim of this study is to determine the real incidence of upper tract urothelial carcinoma (UTUC) in Spain. MATERIAL AND METHODS: A descriptive, prospective and multicenter epidemiological study was conducted in 31 Spanish facilities by means of the Platform for Multicenter Studies of the Spanish Association of Urology. Recruitment was opened from May 1st , 2017 to April 30th , 2018...
September 2020: Actas urologicas españolas
#27
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2020: American Journal on Intellectual and Developmental Disabilities
#28
A R Salem, P Martínez Pulido, F Sanchez, Y Sanchez, D Rojo, A J Español, M E Sales
No abstract text is available yet for this article.
June 23, 2020: International Immunopharmacology
#29
JOURNAL ARTICLE
J Aguilera, M V de Gálvez, P Aguilera, M de Troya, Y Gilaberte
No abstract text is available yet for this article.
November 2020: Actas dermo-sifiliográficas
#30
Mercè Codina, Rosa Corcoy, María M Goya
No abstract text is available yet for this article.
October 2020: Endocrinología, diabetes y nutrición
#31
JOURNAL ARTICLE
Lorena V Zárate, Carolina A Pontillo, Alejandro Español, Noelia V Miret, Florencia Chiappini, Claudia Cocca, Laura Álvarez, Diana Kleiman de Pisarev, María E Sales, Andrea S Randi
Breast cancer incidence is increasing globally and pesticides exposure may impact risk of developing this disease. Hexachlorobenzene (HCB) and chlorpyrifos (CPF) act as endocrine disruptors, inducing proliferation in breast cancer cells. Vascular endothelial growth factor-A (VEGF-A), cyclooxygenase-2 (COX-2) and nitric oxide (NO) are associated with angiogenesis. Our aim was to evaluate HCB and CPF action, both weak aryl hydrocarbon receptor (AhR) ligands, on angiogenesis in breast cancer models. We used: (1) in vivo xenograft model with MCF-7 cells, (2) in vitro breast cancer model with MCF-7, and (3) in vitro neovasculogenesis model with endothelial cells exposed to conditioned medium from MCF-7...
June 8, 2020: Toxicology and Applied Pharmacology
#32
JOURNAL ARTICLE
Vicenç Torrente-Segarra, Tarek C Salman-Monte, Íñigo Rúa-Figueroa, Víctor Del Campo, Francisco Javier López-Longo, María Galindo-Izquierdo, Jaime Calvo-Alén, Alejandro Olivé-Marqués, Coral Mouriño-Rodríguez, Loreto Horcada, Cristina Bohórquez, Carlos Montilla, Eva Salgado, Elvira Díez-Álvarez, Ricardo Blanco, José Luis Andreu, Olaia Fernández-Berrizbeitia, Lorena Expósito, Marian Gantes, Blanca Hernández-Cruz, Ángela Pecondón-Español, Nuria Lozano-Rivas, Gema Bonilla, Ana Lois Iglesias, Paula Rubio-Muñoz, Juan Ovalles, Eva Tomero, Alina Boteanu, Javier Narvaez, Mercedes Freire, Paloma Vela, Víctor Quevedo-Vila, Antonio Juan Mas, Santiago Muñoz-Fernández, Enrique Raya, Mireia Moreno, M L Velloso-Feijoo, Gregorio Soler, Tomás Ramón Vázquez-Rodríguez, José M Pego-Reigosa
OBJECTIVE: To assess the incidence of serious infection (SI) and associated factors in a large juvenile-onset systemic lupus erythematosus (jSLE) retrospective cohort. METHODS: All patients in the Spanish Rheumatology Society Lupus Registry (RELESSER) who meet ≥4 ACR-97 SLE criteria and disease onset <18 years old (jSLE), were retrospectively investigated for SI (defined as either the need for hospitalization with antibacterial therapy for a potentially fatal infection or death caused by the infection)...
May 30, 2020: Seminars in Arthritis and Rheumatism
#33
JOURNAL ARTICLE
Juan-José Garcés, Gabriel Bretones, Leire Burgos, Rafael Valdes-Mas, Noemi Puig, Maria-Teresa Cedena, Diego Alignani, Idoia Rodriguez, Diana Álvarez Puente, Miguel-García Álvarez, Ibai Goicoechea, Sara Rodriguez, Maria-Jose Calasanz, Xabier Agirre, Juan Flores-Montero, Luzalba Sanoja-Flores, Paula Rodriguez-Otero, Rafael Rios, Joaquin Martinez-Lopez, Pamela Millacoy, Luis Palomera, Rafael Del Orbe, Albert Pérez-Montaña, Halima El Omri, Felipe Prosper, Maria-Victoria Mateos, Laura Rosiñol, Joan Blade, Juan-Jose Lahuerta, Alberto Orfao, Carlos Lopez-Otin, Jesus F San Miguel, Bruno Paiva
Multiple myeloma (MM) patients undergo repetitive bone marrow (BM) aspirates for genetic characterization. Circulating tumor cells (CTCs) are detectable in peripheral blood (PB) of virtually all MM cases and are prognostic, but their applicability for noninvasive screening has been poorly investigated. Here, we used next-generation flow (NGF) cytometry to isolate matched CTCs and BM tumor cells from 53 patients and compared their genetic profile. In eight cases, tumor cells from extramedullary (EM) plasmacytomas were also sorted and whole-exome sequencing was performed in the three spatially distributed tumor samples...
November 2020: Leukemia
#34
JOURNAL ARTICLE
Eduardo Espinet Coll, Román Turró Arau, Aitor Orive Calzada, Carlos Dolz Abadía, Amador García Ruiz de Gordejuela, Andrés Sánchez Yagüe, Javier Nebreda Durán, Manoel Galvao Neto, Gontrand López-Nava Breviere, Alfredo Mata Bilbao, Alfonso Alcalde Vargas, Ramón Abad Belando, Andrés José Del Pozo-García, José Miguel Esteban López-Jamar, Jordi Pujol Gebelli, Antonio José Torres García, José Antonio Ramírez Felipe, Miguel Muñoz Navas
Bariatric endoscopy (BE) encompasses a number of techniques -some consolidated, some under development- aiming to contribute to the management of obese patients and their associated metabolic diseases as a complement to dietary and lifestyle changes. To date different intragastric balloon models, suture systems, aspiration methods, substance injections and both gastric and duodenal malabsorptive devices have been developed, as well as endoscopic procedures for the revision of bariatric surgery. Their ongoing evolution conditions a gradual increase in the quantity and quality of scientific evidence about their effectiveness and safety...
June 2020: Revista Española de Enfermedades Digestivas
#35
JOURNAL ARTICLE
Gemma Español-Martín, Mireia Pagerols, Raquel Prat, Cristina Rivas, Laura Sixto, Sergi Valero, María Soler Artigas, Marta Ribasés, Josep A Ramos-Quiroga, Miquel Casas, Rosa Bosch
The Strengths and Difficulties Questionnaire (SDQ) has been extensively used to measure common forms of psychopathology among children and adolescents. However, its psychometric properties vary across countries and several controversial issues warrant further investigation. This study aimed to evaluate whether the Spanish version of the SDQ is a reliable and valid tool for assessing emotional and behavioral problems in a sample of 6,775 students aged 5 to 17 years, as rated by parents, teachers, and youth. We examined the internal consistency of the questionnaire, its factor structure, and measurement invariance across child's gender and age...
May 25, 2020: Assessment
#36
MULTICENTER STUDY
Mary Gleeson, Nicholas Counsell, David Cunningham, Anthony Lawrie, Laura Clifton-Hadley, Eliza Hawkes, Andrew McMillan, Kirit M Ardeshna, Cathy Burton, Nick Chadwick, Joanna Gambell, Paul Smith, Paul Mouncey, Christopher Pocock, John Radford, John Davies, Deborah Turner, Anton Kruger, Peter Johnson, David Linch
We compared the International Prognostic Index (IPI), Revised (R)-IPI and age-adjusted (aa)-IPI as prognostic indices for patients with diffuse large B-cell lymphoma (DLBCL) in the UK National Cancer Research Institute (NCRI) R-CHOP 14 versus 21 trial (N = 1080). The R-IPI and aa-IPI showed no marked improvement compared to the IPI for overall and progression-free survival, in terms of model fit or discrimination. Similar results were observed in exploratory analyses incorporating the Grupo Español de Linfomas/Transplante de Médula Ósea (GELTAMO)-IPI, where baseline β2-microglobulin data were available (N = 655)...
March 2021: British Journal of Haematology
#37
MULTICENTER STUDY
Isabel González-Gascón-Y-Marín, Carolina Muñoz-Novas, Iñigo Figueroa, María Hernández-Sánchez, Ana-Eugenia Rodríguez-Vicente, Miguel Quijada-Álamo, Claudia Pérez-Carretero, Carol Moreno, Rosa Collado, Blanca Espinet, Anna Puiggros, Natalia de Las Heras, Francesc Bosch, José-Ángel Hernández
BACKGROUND: The discovery of new biologic variables with high prognostic effect has been accompanied by the emergence of different prognostic indexes (PIs) to assess the time to first treatment in patients with early-stage (Binet A) chronic lymphocytic leukemia (CLL). The present study compared the prognostic value of 5 PIs: CLL international prognostic index (CLL-IPI), Barcelona-Brno, international prognostic score-A (IPS-A), CLL-01, and a tailored approach. PATIENTS AND METHODS: We applied the 5 PIs to a cohort of 428 unselected patients with Binet A CLL from a multicenter Spanish database with clinical and biologic information available...
August 2020: Clinical Lymphoma, Myeloma & Leukemia
#38
JOURNAL ARTICLE
D Duque-Zumajo, J A de la Torre, Pep Español
We study through MD simulations the correlation matrix of the discrete transverse momentum density field in real space for an unconfined Lennard-Jones fluid at equilibrium. Mori theory predicts this correlation under the Markovian approximation from the knowledge of the non-local shear viscosity matrix, which is given in terms of a Green-Kubo formula. However, the running Green-Kubo integral for the non-local shear viscosity does not have a plateau. By using a recently proposed correction for the Green-Kubo formula that eliminates the plateau problem [Español et al...
May 7, 2020: Journal of Chemical Physics
#39
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
May 2020: American Journal on Intellectual and Developmental Disabilities
#40
JOURNAL ARTICLE
A R Salem, P Martínez Pulido, F Sanchez, Y Sanchez, A J Español, M E Sales
The non-neuronal cholinergic system refers to the presence of acetylcholine, choline acetyltransferase, acetylcholinesterase and cholinergic receptors, nicotinic and muscarinic (mAChRs) expressed in non-neuronal cells. The presence of mAChRs has been detected in different type of tumor cells and they are linked with tumorigenesis. We had previously documented the expression of mAChRs in murine and human mammary adenocarcinomas and the absence of these receptors in normal mammary cells of the same origins. We also demonstrated that mAChRs are involved in breast cancer progression, pointing to a main role for mAChRs as oncogenic proteins...
April 17, 2020: International Immunopharmacology
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