keyword
MENU ▼
Read by QxMD icon Read
search

Español

keyword
https://www.readbyqxmd.com/read/28498784/depth-of-response-in-multiple-myeloma-a-pooled-analysis-of-three-pethema-gem-clinical-trials
#1
Juan-Jose Lahuerta, Bruno Paiva, Maria-Belen Vidriales, Lourdes Cordón, Maria-Teresa Cedena, Noemi Puig, Joaquin Martinez-Lopez, Laura Rosiñol, Norma C Gutierrez, María-Luisa Martín-Ramos, Albert Oriol, Ana-Isabel Teruel, María-Asunción Echeveste, Raquel de Paz, Felipe de Arriba, Miguel T Hernandez, Luis Palomera, Rafael Martinez, Alejandro Martin, Adrian Alegre, Javier De la Rubia, Alberto Orfao, María-Victoria Mateos, Joan Blade, Jesus F San-Miguel
Purpose To perform a critical analysis on the impact of depth of response in newly diagnosed multiple myeloma (MM). Patients and Methods Data were analyzed from 609 patients who were enrolled in the GEM (Grupo Español de Mieloma) 2000 and GEM2005MENOS65 studies for transplant-eligible MM and the GEM2010MAS65 clinical trial for elderly patients with MM who had minimal residual disease (MRD) assessments 9 months after study enrollment. Median follow-up of the series was 71 months. Results Achievement of complete remission (CR) in the absence of MRD negativity was not associated with prolonged progression-free survival (PFS) and overall survival (OS) compared with near-CR or partial response (median PFS, 27, 27, and 29 months, respectively; median OS, 59, 64, and 65 months, respectively)...
May 12, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28474478/incomplete-cavernous-sinus-syndrome-as-the-initial-manifestation-of-a-previously-undetected-metastatic-prostate-adenocarcinoma
#2
María Machío Castelló, Diego Escobar Montatixe, Carlos Cenjor Español, José Miguel Villacampa Aubá, Julia Montoya Bordón, Rafael Carias Calix, Rafael Sáez Pinel
BACKGROUND: Cavernous sinus syndrome presents as unilateral ophthalmoplegia associated with sympathetic denervation, pain, paresthesias, and V1 and V2 distribution numbness. The etiology may be vascular, inflammatory, infectious, and, less commonly, neoplastic (metastatic). METHODS: We report a patient with incomplete cavernous sinus syndrome as the initial manifestation of previously undetected metastatic prostate adenocarcinoma. RESULTS: A 59-year-old man presented with a 2-month history of left hemicranial headaches with ptosis and binocular diplopia...
May 5, 2017: Head & Neck
https://www.readbyqxmd.com/read/28457904/collagenous-colitis-requirement-for-high-dose-budesonide-as-maintenance-treatment
#3
Fernando Fernandez-Bañares, Marta Piqueras, Danila Guagnozzi, Virginia Robles, Alexandra Ruiz-Cerulla, María José Casanova, Javier P Gisbert, David Busquets, Yolanda Arguedas, Angeles Pérez-Aisa, Luis Fernández-Salazar, Alfredo J Lucendo
BACKGROUND: Controlled studies show high efficacy of budesonide in inducing short-term clinical remission in collagenous colitis (CC), but relapses are common after its withdrawal. AIM: To evaluate the need for high-dose budesonide (≥6mg/d) to maintain clinical remission in CC. METHODS: Analysis of a multicentre retrospective cohort of 75 patients with CC (62.3±1.5years; 85% women) treated with budesonide in a clinical practice setting between 2013 and 2015...
April 10, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28452579/res%C3%A3%C2%BAmenes-al-espa%C3%A3-ol
#4
(no author information available yet)
No abstract text is available yet for this article.
May 2017: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28433642/predicting-non-muscle-invasive-bladder-cancer-recurrence-and-progression-in-a-us-population
#5
Kourosh Ravvaz, Marcus E Walz, John A Weissert, Tracy M Downs
PURPOSE: To assess performance of The European Organization for Research and Treatment of Cancer (EORTC) and Club Urologico Español de Tratamiento Oncologico (CUETO) non-muscle invasive bladder cancer (NMIBC) predictive models compared to current US National Comprehensive Cancer Network (NCCN) treatment guidelines in a US population. MATERIALS AND METHODS: Retrospective analysis using electronic medical records of patients with NMIBC within a multicenter US patient population...
April 19, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28433024/perspective-dissipative-particle-dynamics
#6
Pep Español, Patrick B Warren
Dissipative particle dynamics (DPD) belongs to a class of models and computational algorithms developed to address mesoscale problems in complex fluids and soft matter in general. It is based on the notion of particles that represent coarse-grained portions of the system under study and allow, therefore, reaching time and length scales that would be otherwise unreachable from microscopic simulations. The method has been conceptually refined since its introduction almost twenty five years ago. This perspective surveys the major conceptual improvements in the original DPD model, along with its microscopic foundation, and discusses outstanding challenges in the field...
April 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28421808/insatisfacci%C3%A3-n-con-la-imagen-corporal-en-ni%C3%A3-os-y-adolescentes-revisi%C3%A3-n-sistem%C3%A3-tica
#7
Paloma Jiménez Flores, Arturo Jiménez Cruz, Montserrat Bacardi Gascón
Introducción: la diferencia de la percepción entre la silueta percibida y la deseada se ha definido como insatisfacción con la imagen corporal (IMCO).Objetivo: evaluar los métodos utilizados para medir la IMCO y la frecuencia de la IMCO en niños y adolescentes.Metodología: se buscaron artículos registrados en las bases de datos de PubMed, EBSCOhost y Scielo, de estudios transversales en inglés y español, que valoraran la IMCO en niños y adolescentes publicados de abril de 2010 al mes de abril de 2015...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28396659/disease-phenotype-and-outcome-depending-on-the-age-at-disease-onset-in-patients-carrying-the-r92q-low-penetrance-variant-in-tnfrsf1a-gene
#8
Estíbaliz Ruiz-Ortiz, Estíbaliz Iglesias, Alessandra Soriano, Segundo Buján-Rivas, Marta Español-Rego, Raul Castellanos-Moreira, Adrià Tomé, Jordi Yagüe, Jordi Antón, José Hernández-Rodríguez
BACKGROUND: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal-dominant autoinflammatory disease caused by mutations in the TNFRSF1A gene. R92Q, a low-penetrance variant, is usually associated with a milder TRAPS phenotype than structural or pathogenic mutations. No studies differentiating R92Q-related disease in patients with pediatric and adult onset have been performed to date. OBJECTIVE: To analyze clinical features and disease outcomes in patients diagnosed with TRAPS associated with R92Q variant and to investigate differences between patients with pediatric and adult disease onset...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28389854/a-reduced-12-joint-ultrasound-examination-predicts-lack-of-x-ray-progression-better-than-clinical-remission-criteria-in-patients-with-rheumatoid-arthritis
#9
Eugenio de Miguel, Angela Pecondón-Español, Manuel Castaño-Sánchez, Alfonso Corrales, Ricardo Gutierrez-Polo, Manuel Rodriguez-Gomez, Jose A Pinto-Tasende, Jose L Rivas, José Ivorra-Cortés
To study the predictive value of clinical remission definitions and ultrasound (US) examination on X-ray progression in rheumatoid arthritis (RA). This was an observational prospective multicenter 1-year follow-up cohort of RA patients with moderate disease activity (3.2 < DAS28 ≤ 5.1) who started anti-TNF therapy. DAS28ESR, DAS28CRP, SDAI, CDAI, and ACR/EULAR remission criteria were applied and reduced 12-joint US examination was performed at baseline and at 6 and 12 months. At baseline and month 12, radiographs of hands and feet were obtained in a subset of patients...
April 7, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28375802/res%C3%A3%C2%BAmenes-al-espa%C3%A3-ol
#10
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28370234/enumerating-bone-marrow-blasts-from-nonerythroid-cellularity-improves-outcome-prediction-in-myelodysplastic-syndromes-and-permits-a-better-definition-of-the-intermediate-risk-category-of-the-revised-international-prognostic-scoring-system-ipss-r
#11
Xavier Calvo, Leonor Arenillas, Elisa Luño, Leonor Senent, Montserrat Arnan, Fernando Ramos, Carme Pedro, Mar Tormo, Julia Montoro, María Díez-Campelo, María Laura Blanco, Beatriz Arrizabalaga, Blanca Xicoy, Santiago Bonanad, Andrés Jerez, Meritxell Nomdedeu, Ana Ferrer, Guillermo F Sanz, Lourdes Florensa
The Revised International Prognostic Scoring System (IPSS-R) has been recognized as the score with the best outcome prediction capability in MDS, but this brought new concerns about the accurate prognostication of patients classified into the intermediate risk category. The correct enumeration of blasts is essential in prognostication of MDS. Recent data evidenced that considering blasts from nonerythroid cellularity (NECs) improves outcome prediction in the context of IPSS and WHO classification. We assessed the percentage of blasts from total nucleated cells (TNCs) and NECs in 3924 MDS patients from the GESMD, 498 of whom were MDS with erythroid predominance (MDS-E)...
March 28, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28351781/geis-guidelines-for-gastrointestinal-sarcomas-gist
#12
REVIEW
Andrés Poveda, Xavier García Del Muro, Jose Antonio López-Guerrero, Ricardo Cubedo, Virginia Martínez, Ignacio Romero, César Serrano, Claudia Valverde, Javier Martín-Broto
Gastrointestinal stromal sarcomas (GISTs) are the most common mesenchymal tumours originating in the digestive tract. They have a characteristic morphology, are generally positive for CD117 (c-kit) and are primarily caused by activating mutations in the KIT or PDGFRA genes(1). On rare occasions, they occur in extravisceral locations such as the omentum, mesentery, pelvis and retroperitoneum. GISTs have become a model of multidisciplinary work in oncology: the participation of several specialties (oncologists, pathologists, surgeons, molecular biologists, radiologists…) has forested advances in the understanding of this tumour and the consolidation of a targeted therapy, imatinib, as the first effective molecular treatment in solid tumours...
April 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28322111/hpv-in-larynx-squamous-cell-carcinoma-new-serotypes-and-survival-study-within-10-year-follow-up
#13
Alvaro Sánchez Barrueco, Fernando González Galán, David Lora Pablos, José Miguel Villacampa Aubá, Claudio Ballestín Carcavilla, Carlos Cenjor Español, Carlos Almodóvar Álvarez
Objective To determine the presence of human papillomavirus (HPV) in head and neck squamous cell carcinoma, specifically in the larynx without the bias of other sublocations, and to describe the different serotypes of HPV and their impact on overall and disease-free survival after 10-year follow-up. Study Design Retrospective case series with chart review of ear, nose, and throat oncologic database. Setting Academic tertiary care hospital. Subjects A total of 123 samples of larynx squamous cell carcinoma were included, only from the glottis and treated only with surgery between 1977 and 2005...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28301947/multicenter-study-on-the-safety-of-bariatric-endoscopy
#14
Eduardo Espinet Coll, Javier Nebreda Durán, Gontrand López-Nava Breviere, Julio Ducóns García, Manuel Rodríguez-Téllez, Javier Crespo García, Carlos Marra-López Valenciano
INTRODUCTION: Bariatric endoscopy includes a series of specific techniques focused on the management of obese patients. As a quality criterion, safety as expressed by a minimal incidence of serious complications is required in addition to efficacy. METHODS: A descriptive, retrospective, multicenter review of the experience recorded at seven hospitals included in the Grupo Español de Endoscopia Bariátrica (GETTEMO) in order to document the incidence, cause, and resolution (including legal consequences) of serious complications reported for each bariatric technique, and according to endoscopist expertise...
March 17, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28292529/-spanish-adaptation-of-the-2016-european-guidelines-on-cardiovascular-disease-prevention-in-clinical-practice
#15
Miguel Ángel Royo-Bordonada, Pedro Armario, José María Lobos Bejarano, Juan Pedro-Botet, Fernando Villar Álvarez, Roberto Elosua, Carlos Brotons Cuixart, Olga Cortés, Benilde Serrano, Miguel Camafort Babkowski, Antonio Gil Núñez, Antonio Pérez, Antonio Maiques, Ana de Santiago Nocito, Almudena de Castro, Eduardo Alegría, Ciro Baeza, María Herranz, Susana Sans, Pilar Campos
The VI European Guidelines for Cardiovascular Prevention recommend combining population and high-risk strategies with lifestyle changes as a cornerstone of prevention, and propose the SCORE function to quantify cardiovascular risk. The guidelines highlight disease specific interventions, and conditions as women, young people and ethnic minorities. Screening for subclinical atherosclerosis with noninvasive imaging techniques is not recommended. The guidelines distinguish four risk levels (very high, high, moderate and low) with therapeutic objectives for lipid control according to risk...
May 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28259425/incidence-associated-factors-and-clinical-impact-of-severe-infections-in-a-large-multicentric-cohort-of-patients-with-systemic-lupus-erythematosus
#16
Íñigo Rúa-Figueroa, Javier López-Longo, María Galindo-Izquierdo, Jaime Calvo-Alén, Víctor Del Campo, Alejandro Olivé-Marqués, Sabina Pérez-Vicente, Antonio Fernández-Nebro, Mariano Andrés, Celia Erausquin, Eva Tomero, Loreto Horcada, Esther Uriarte, Mercedes Freire, Carlos Montilla, Ana Sánchez-Atrio, Gregorio Santos, Alina Boteanu, Elvira Díez-Álvarez, Javier Narváez, Víctor Martínez-Taboada, Lucía Silva-Fernández, Esther Ruiz-Lucea, José Luis Andreu, José Ángel Hernández-Beriain, Marian Gantes, Blanca Hernández-Cruz, José Pérez-Venegas, Ángela Pecondón-Español, Carlos Marras, Mónica Ibáñez-Barceló, Gema Bonilla, Vicente Torrente, Iván Castellví, Juan José Alegre, Joan Calvet, Jose Luis Marenco, Enrique Raya, Tomás Vázquez, Victor Quevedo, Santiago Muñoz-Fernández, Manuel Rodríguez-Gómez, Jesús Ibáñez, José M Pego-Reigosa
OBJECTIVES: To estimate the incidence of severe infection and investigate the associated factors and clinical impact in a large systemic lupus erythematosus (SLE) retrospective cohort. METHODS: All patients in the Spanish Rheumatology Society Lupus Registry (RELESSER) who meet ≥4 ACR-97 SLE criteria were retrospectively investigated for severe infections. Patients with and without infections were compared in terms of SLE severity, damage, comorbidities, and demographic characteristics...
January 27, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28257239/res%C3%A3%C2%BAmenes-al-espa%C3%A3-ol
#17
(no author information available yet)
No abstract text is available yet for this article.
March 2017: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28248628/cultural-and-linguistic-adaptation-of-a-healthy-diet-text-message-intervention-for-hispanic-adults-living-in-the-united-states
#18
Linda D Cameron, Arturo Durazo, A Susana Ramírez, Roberto Corona, Mayra Ultreras, Sonia Piva
Hispanics represent a critical target for culturally adapted diet interventions. In this formative research, we translated HealthyYouTXT, an mHealth program developed by the U.S. National Cancer Institute, into HealthyYouTXT en Español, a linguistically and culturally appropriate version for Spanish speakers in the United States. We report a three-stage, mixed-methods process through which we culturally adapted the text messages, evaluated their acceptability, and revised the program based on the findings...
March 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28244786/prevalencia-de-las-declaraciones-nutricionales-en-la-prevenci%C3%A3-n-de-la-obesidad-en-el-mercado-espa%C3%A3-ol
#19
Belinda Lopéz-Galán, Tiziana De Magistris
Introducción: a pesar de que estudios anteriores han proporcionado información relevante respecto al avance en la aplicación del Reglamento (CE) n.o 1924/2006 de la Unión Europea, hasta ahora no se ha determinado la prevalencia de las declaraciones nutricionales relevantes en la prevención de la obesidad en el mercado español.Objetivo: determinar la presencia de las declaraciones nutricionales relevantes en la prevención de la obesidad en el mercado español.Materiales y métodos: se realizó un registro de productos alimenticios comercializados en 3 cadenas de distribución alimentaria que concentran el 40% del mercado...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28236475/update-of-the-grupo-espa%C3%A3-ol-de-leucemia-linfoc%C3%A3-tica-cr%C3%A3-nica-clinical-guidelines-of-the-management-of-chronic-lymphocytic-leukemia
#20
José A García-Marco, Julio Delgado, José A Hernández-Rivas, Ángel Ramírez Payer, Javier Loscertales Pueyo, Isidro Jarque, Pau Abrisqueta, Pilar Giraldo, Rafael Martínez, Lucrecia Yáñez, Mª José Terol, Marcos González, Francesc Bosch
BACKGROUND AND OBJECTIVE: The broad therapeutic arsenal and the biological heterogeneity of patients with chronic lymphocytic leukemia (CLL) makes it difficult to standardize treatment for CLL patients with specific clinical settings in routine clinical practice. These considerations prompted us to elaborate the present consensus document, which constitutes an update of the previous version published in 2013, mainly focusing on novel treatment strategies that have been developed over last 5 years, namely B-cell receptor inhibitors (ibrutinib and idelalisib), anti-CD20 monoclonal antibodies (ofatumumab and obinutuzumab), and Bcl-2 inhibitors (venetoclax)...
February 21, 2017: Medicina Clínica
keyword
keyword
1171
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"