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Won-Jae Lee

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https://www.readbyqxmd.com/read/29054019/emergency-preparedness-for-the-accidental-release-of-radionuclides-from-the-uljin-nuclear-power-plant-in-korea
#1
Soon-Ung Park, In-Hye Lee, Seung Jin Joo, Jae-Won Ju
Site specific radionuclide dispersion databases were archived for the emergency response to the hypothetical releases of (137)Cs from the Uljin nuclear power plant in Korea. These databases were obtained with the horizontal resolution of 1.5 km in the local domain centered the power plant site by simulations of the Lagrangian Particle Dispersion Model (LPDM) with the Unified Model (UM)-Local Data Assimilation Prediction System (LDAPS). The Eulerian Dispersion Model-East Asia (EDM-EA) with the UM-Global Data Assimilation Prediction System (UM-GDAPS) meteorological models was used to get dispersion databases in the regional domain...
October 17, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29053486/retrospective-analysis-of-sinus-membrane-thickening-profile-causal-factors-and-its-influence-on-complications
#2
Hyun-Chang Lim, Ji-Yeon Nam, Jae-Kook Cha, Jung-Seok Lee, Dong-Woon Lee, Ui-Won Jung, Seong-Ho Choi
PURPOSE: To retrospectively determine the profile of the sinus membrane (SM), potential factors affecting SM thickening (SMT), and the correlation between SMT and sinus augmentation (SA) complications. MATERIALS AND METHODS: In the patients who received lateral SA, SMT was classified in sagittal sections of cone-beam computed tomography according to its thickness and morphology. The correlation between SMT and the following factors was analyzed: age, sex, endodontic and periodontic statuses of neighboring teeth, and shape of the sinus inferior border...
October 17, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/29052827/primary-exploration-for-radial-nerve-palsy-associated-with-unstable-closed-humeral-shaft-fracture
#3
Soo Hong Han, In Tae Hong, Ho Jae Lee, Sang June Lee, Uk Kim, Dong Won Kim
BACKGROUND: The treatment of radial nerve palsy caused by closed humeral shaft fracture is a matter of debate. The purpose of this study is to evaluate the outcome of early surgical management of radial nerve palsy in patients with unstable closed humeral shaft fractures and to determine whether patients with this injury should be surgically explored. METHODS: Medical records of 15 consecutive patients who had undergone open reduction and internal fixation for unstable closed humeral shaft fractures were reviewed...
September 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29052098/comparative-transcriptome-analysis-reveals-whole-genome-duplications-and-gene-selection-patterns-in-cultivated-and-wild-chrysanthemum-species
#4
So Youn Won, Soo-Jin Kwon, Tae-Ho Lee, Jae-A Jung, Jung Sun Kim, Sang-Ho Kang, Seong-Han Sohn
Comparative transcriptome analysis of wild and cultivated chrysanthemums provides valuable genomic resources and helps uncover common and divergent patterns of genome and gene evolution in these species. Plants are unique in that they employ polyploidy (or whole-genome duplication, WGD) as a key process for speciation and evolution. The Chrysanthemum genus is closely associated with hybridization and polyploidization, with Chrysanthemum species exhibiting diverse ploidy levels. The commercially important species, C...
October 19, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/29051476/independent-factors-predicting-postoperative-30-day-mortality-in-101-infants-following-liver-transplantation
#5
Chan Woo Cho, Sanghoon Lee, Jong Man Kim, Gyu-Seong Choi, Choon Hyuck David Kwon, Jae-Won Joh, Suk-Koo Lee
BACKGROUND Liver transplantation (LT) in infants is a challenging procedure. This study was designed to identify risk factors of 30-day mortality of infant LT recipients. MATERIAL AND METHODS A total of 101 infants treated between May 1997 and March 2015 were assigned to one of two groups, a deceased infant group (n=9) or a live infant group (n=92), according to their mortality status at 30 days after LT. RESULTS Patient characteristics of height, weight, preoperative total bilirubin, creatinine clearance, primary diagnosis, and graft-to-recipient weight ratio (GRWR) were significantly different between the two groups...
October 20, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29050960/mapping-patterns-of-locoregional-recurrence-following-contemporary-treatment-with-radiation-therapy-for-breast-cancer-a-multi-institutional-validation-study-of-the-estro-consensus-guideline-on-clinical-target-volume
#6
Jee Suk Chang, Jeongshim Lee, Mison Chun, Kyung Hwan Shin, Won Park, Jong Hoon Lee, Jin Hee Kim, Won Sup Yoon, Ik Jae Lee, Juree Kim, Hye Li Park, Yong Bae Kim
BACKGROUND AND PURPOSE: To validate the ESTRO guideline on clinical target volume (CTV) delineation for breast cancer using a multi-centre dataset. MATERIALS AND METHODS: Patients with axial imaging of gross locoregional recurrence (LRR) were identified from 10 participating institutions. All patients received RT, albeit not to all regional node. The location of LRR was transferred to the corresponding area on representative axial computed tomography images and compared with ESTRO-CTV...
October 16, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29049519/association-of-bone-mineral-density-with-the-risk-of-intracranial-aneurysm
#7
Yong-Won Shin, Kyung-Il Park, Jangsup Moon, Soon-Tae Lee, Kon Chu, Sang Kun Lee, Jae-Kyu Roh, Keun-Hwa Jung
Importance: Disruption of extracellular matrix integrity is critically involved in both intracranial aneurysm and bone fragility. Furthermore, both intracranial aneurysm and osteoporosis have a female predominance, and sex hormones are considered to affect this discrepancy. Objective: To evaluate the association between bone mineral density and intracranial aneurysm. Design, Setting, and Participants: A cross-sectional study conducted with 14 328 patients who underwent brain magnetic resonance angiography and bone mineral densitometry as a part of a health examination at a specialized center for comprehensive health examination in Seoul, the largest metropolitan area in the Republic of Korea, between December 2004 and November 2015...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29047150/rebamipide-alleviates-radiation-induced-colitis-through-improvement-of-goblet-cell-differentiation-in-mice
#8
Hyosun Jang, Sunhoo Park, Janet Lee, Jae Kyung Myung, Won-Suk Jang, Sun-Joo Lee, Hyunwook Myung, Changsun Lee, Hyewon Kim, Seung-Sook Lee, Young-Woo Jin, Sehwan Shim
BACKGROUND AND AIM: Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation. Goblet cells play a pivotal role in the intestinal barrier against pathogenic bacteria. Rebamipide, anti-gastric ulcer drug, has the effects to promote goblet cell proliferation. The aim of this study was to investigate whether radiation-induced colonic injury could be alleviated by rebamipide. METHODS: We orally administered rebamipide for 6 days to mice, which were subjected to 13 Gy abdominal irradiation, to evaluate the therapeutic effects of rebamipide against radiation-induced colitis...
October 19, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29046812/relationship-of-activities-outside-work-to-sleep-and-depression-anxiety-disorders-in-korean-workers-the-4th-korean-working-condition-survey
#9
Kyung-Jae Lee, Sung Won Jung, Hee Sung Lee, Guang Hwi Kim, Jae Gwang Lee, June-Hee Lee, Joo Ja Kim
BACKGROUND: Sleep disorders and depression/anxiety disorders are long-standing and significant problem for mental health. Also there are already known so many negative health effect of these disorders. But there were few studies to examine the association between activities outside work and forementioned disorders. So this study aimed the association of those things by using the Republic of Korean data. METHODS: Data from 32,232 wage workers were used in the 4th Korean Working Condition Survey...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29046699/age-dependent-differences-in-myelin-basic-protein-expression-in-the-hippocampus-of-young-adult-and-aged-gerbils
#10
Ji Hyeon Ahn, Tae-Kyeong Lee, Joon Ha Park, Jeong Hwi Cho, In Hye Kim, Jae Chul Lee, Seongkweon Hong, Yong Hwan Jeon, Il Jun Kang, Young Joo Lee, Moo-Ho Won, Choong-Hyun Lee
Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus, CA2/3 and CA1 areas) of gerbils of various ages; young (1 month), adult (6 months) and aged (24 months), using western blot and immunohistochemistry. Western blot results showed tendencies of age-related reductions of MBP levels. MBP immunoreactivity was significantly decreased with age in synaptic sites of trisynaptic loops, perforant paths, mossy fibers, and Schaffer collaterals...
September 2017: Laboratory Animal Research
https://www.readbyqxmd.com/read/29044883/clinical-benefit-and-residual-kidney-function-of-en-bloc-nephrectomy-for-perirenal-retroperitoneal-sarcoma
#11
Chan Woo Cho, Kyo Won Lee, Hyojun Park, Hyung Joon Kim, Jae Berm Park, Yoon-La Choi, Jeong Il Yu, Su Jin Lee, Dong Il Choi, Sung Joo Kim
AIM: The purpose of this study was to evaluate the efficacy of en bloc nephrectomy for perirenal retroperitoneal sarcoma (RPS) with respect to postoperative kidney function and oncological benefits. METHODS: We performed a comparative study of 114 patients undergoing surgery for primary RPS, classifying cases as nephrectomy (NPX, n = 65) versus no nephrectomy (no-NPX, n = 49). The Δ and % change between preoperative and postoperative estimated glomerulus filtration rate (eGFR) were analyzed to compare renal function changes after surgery...
October 18, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29043236/efficacy-of-eculizumab-in-paroxysmal-nocturnal-hemoglobinuria-patients-with-or-without-aplastic-anemia-prospective-study-of-a-korean-pnh-cohort
#12
Chul Won Choi, Jun Ho Jang, Jin Seok Kim, Deog-Yeon Jo, Je-Hwan Lee, Sung-Hyun Kim, Yeo-Kyeoung Kim, Jong-Ho Won, Joo Seop Chung, Hawk Kim, Jae Hoon Lee, Min Kyoung Kim, Hyeon-Seok Eom, Shin Young Hyun, Jeong-A Kim, Jong Wook Lee
BACKGROUND: Patients with paroxysmal nocturnal hemoglobinuria (PNH) often have concurrent aplastic anemia (AA). This study aimed to determine whether eculizumab-treated patients show clinical benefit regardless of concurrent AA. METHODS: We analyzed 46 PNH patients ≥18 years of age who were diagnosed by flow cytometry and treated with eculizumab for more than 6 months in the prospective Korean PNH registry. Patients were categorized into two groups: PNH patients with concurrent AA (PNH/AA, N=27) and without AA (classic PNH, N=19)...
September 2017: Blood Research
https://www.readbyqxmd.com/read/29043235/platelet-to-lymphocyte-ratio-plr-retains-independent-prognostic-significance-in-advanced-stage-marginal-zone-lymphoma-patients-treated-with-rituximab-cyclophosphamide-vincristine-and-prednisone-combination-chemotherapy-r-cvp-consortium-for-improving-survival
#13
Jeongkuk Seo, Won Seog Kim, Jin Seok Kim, Seok Jin Kim, Jae Hoon Lee, Jun Shik Hong, Gyeong-Won Lee, Sung Yong Oh, Ji-Hyun Lee, Dok Hyun Yoon, Won-Sik Lee, Hyo Jung Kim, Jae-Yong Kwak, Hye Jin Kang, Jae-Cheol Jo, Yong Park, Ho Sup Lee, Hyo-Jin Kim, Cheolwon Suh
BACKGROUND: Rituximab plus cyclophosphamide, vincristine, and prednisone (R-CVP) is one of the effective chemotherapeutic regimens for patients with advanced stage marginal zone lymphoma (MZL). However, prognostic factors that affect the outcome of treatment for MZL are not well understood. METHODS: Between August 2006 and June 2013, patients with newly diagnosed stage III and IV MZL treated with R-CVP as a first-line therapy from 15 institutions were retrospectively analyzed...
September 2017: Blood Research
https://www.readbyqxmd.com/read/29042893/periodic-limb-movements-in-sleep-is-associated-with-increased-mortality
#14
Jae-Won Choi, Ji Soo Song, Yu Jin Lee, Do-Un Jeong
OBJECTIVE: To elucidate the association between periodic limb movements in sleep (PLMS) and mortality. METHODS: Nocturnal polysomnographic recordings of 1,344 subjects obtained from 1995 to 2008 were reviewed. The subjects were divided into four groups based on PLMS and insomnia: reference group (PLMS≤5), insomnia group (PLMS≤5 with insomnia symptoms), 5<PLMS≤15 group, and the PLMS>15 group. We searched each subject's Identification Number in the death records from the Statistics of Korea, the national bureau of statistics, to determine deaths in the cohort that occurred prior to December, 2013...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042888/cognitive-stimulation-as-a-therapeutic-modality-for-dementia-a-meta-analysis
#15
Kayoung Kim, Ji Won Han, Yoonseop So, Jiyeong Seo, You Joung Kim, Joon Hyuk Park, Seok Bum Lee, Jung Jae Lee, Hyun-Ghang Jeong, Tae Hui Kim, Ki Woong Kim
OBJECTIVE: Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials (RCTs) on the efficacy of CS in people with dementia. METHODS: Data sources were identified by searching PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library. A total of 7,354 articles were identified, and of these, 30 RCTs were selected based on the selection criteria...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042885/more-resilience-in-males-with-probable-bipolar-depression-than-probable-unipolar-depression-among-korean-conscripts
#16
Ji-Yeong Seo, Dawon Lee, Dongyun Lee, Boseok Cha, Chul-Soo Park, Bong-Jo Kim, Cheol-Soon Lee, So-Jin Lee, In-Young Ahn, Jae-Won Choi
OBJECTIVE: This study investigated whether the resilience of males with probable bipolar depression (PBD) can be strengthened and compared it to that of males with probable unipolar depression (PUD). METHODS: Prospective data for 198 participants (PBD: 66, PUD: 66, normal control: 66) were analyzed. The participants' resilience, bipolarity and severity of depressive symptoms were evaluated at baseline and after 5 weeks. Analysis of variance (ANOVA) and repeated measure ANOVA was performed for comparing resilience between three groups through a basic military training...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042883/feasibility-of-the-korean-version-of-the-bipolar-depression-rating-scale-in-adolescents-with-early-onset-bipolar-disorder
#17
Da-Young Lee, Eun-Kyung Won, Jung-Won Choi, Hye Ji Min, Jayoun Kim, Kyooseob Ha, Yunglyul Lee, Jae Seung Chang, Yeni Kim
OBJECTIVE: This study explores the feasibility and psychometric properties of the Korean version of the Bipolar Depression Rating Scale (BDRS) in adolescents with Early-onset bipolar disorders. METHODS: Fifty-three participants (aged 13-18) with early-onset bipolar disorders (40 depressed and 18 euthymic, 5 patients were assessed at depressed state and reassessed after remission) were recruited. All participants were assessed using the BDRS, the Hamilton Depression Rating Scale (HAM-D), the Montgomery-Asperg Depression Rating Scale (MADRS), the Young Mania Rating Scale (YMRS), and the Modified Overt Aggression scale (MOAS)...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042796/tert-clptm1-locus-polymorphism-rs401681-is-associated-with-the-prognosis-of-hepatocellular-carcinoma
#18
Hye Won Lee, Won-Jin Park, Yu-Ran Heo, Tae In Park, Soo Young Park, Jae-Ho Lee
Telomere length is associated with the development of hepatocellular carcinoma (HCC), and recent studies have focused on the genetic alteration or polymorphism in telomere-maintaining genes. We examined the clinicopathologic and prognostic value of rs401681 polymorphism, located in the TERT-CLPTM1L locus, in HCC. The relationship between rs401681 variants and telomere length was also analyzed in 156 HCC patients. The rs401681 polymorphism had the following genotype frequencies: C/C in 51.3% of the samples, C/T in 39...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29042648/proteomic-analysis-of-human-lacrimal-and-tear-fluid-in-dry-eye-disease
#19
Jae Hun Jung, Yong Woo Ji, Ho Sik Hwang, Jae Won Oh, Hyun Chang Kim, Hyung Keun Lee, Kwang Pyo Kim
To understand the pathophysiology of dry eye disease (DED), it is necessary to characterize proteins in the ocular surface fluids, including tear fluid (TF) and lacrimal fluid (LF). There have been several reports of TF proteomes, but few proteomic studies have examined LF secreted from the lacrimal gland (LG). Therefore, we characterized the proteins constituting TF and LF by liquid chromatography mass spectrometry. TF and LF were collected from patients with non-Sjögren syndrome DED and from healthy subjects...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29039495/protective-effects-of-neem-azadirachta-indica-a-juss-leaf-extract-against-cigarette-smoke-and-lipopolysaccharide-induced-pulmonary-inflammation
#20
Jae-Won Lee, Hyung Won Ryu, So-Yeon Park, Hyun Ah Park, Ok-Kyoung Kwon, Heung Joo Yuk, Krishna K Shrestha, Minwoo Park, Jung Hee Kim, Sangwoo Lee, Sei-Ryang Oh, Kyung-Seop Ahn
Neem (Azadirachta indica A. Juss.) leaf has been reported to exert anti-inflammatory, antibacterial and antioxidant effects. The purpose of this study was to investigate the protective effects of neem leaf extract (NLE) against cigarette smoke (CS)- and lipopolysaccharide (LPS)-induced pulmonary inflammation. Treatment with NLE significantly attenuated the infiltration of inflammatory cells, such as neutrophils and macrophages in bronchoalveolar lavage fluid (BALF). NLE also reduced the production of reactive oxygen species and the activity of neutrophil elastase in BALF...
October 10, 2017: International Journal of Molecular Medicine
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