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Won-Jae Lee

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https://www.readbyqxmd.com/read/29457964/liver-imaging-reporting-and-data-system-patient-outcomes-for-category-4-and-5-nodules
#1
Sang Hyun Choi, Jae Ho Byun, Young-Suk Lim, So Jung Lee, So Yeon Kim, Hyung Jin Won, Yong Moon Shin, Pyo-Nyun Kim
Purpose To determine the outcomes after initial therapy in patients with chronic liver disease and retrospectively assigned Liver Imaging Reporting and Data System (LI-RADS; version 2014) category 4 (LR-4) and 5 (LR-5) nodules at gadoxetate disodium-enhanced MR imaging. Materials and Methods In this retrospective study, 260 patients with a single LR-4 (n = 132) or LR-5 (n = 128) nodule who were assigned a LI-RADS category were included. Patients were identified between January 2012 and December 2012, and were initially treated by resection, liver transplant, radiofrequency ablation (RFA), or transcatheter arterial chemoembolization (TACE) according to the Barcelona Clinic Liver Cancer staging system...
February 19, 2018: Radiology
https://www.readbyqxmd.com/read/29455048/a-clinical-prediction-score-to-determine-surgical-drainage-of-deep-neck-infection-a-retrospective-case-control-study
#2
Myung Jin Ban, Jae Yeup Jung, Jae Wook Kim, Ki Nam Park, Seung Won Lee, Yoon Woo Koh, Jae Hong Park
BACKGROUND: The objective of this retrospective study was to identify predictors of an abscess guaranteed to be surgically drained successfully in patients with deep neck infection (DNI). MATERIALS AND METHODS: We divided 97 consecutive patients with DNI into a drained group and a non-drained group. We then developed a clinical prediction score and validated it in 32 further patients. RESULTS: Significant predictors of successful surgical drainage (i...
February 15, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29452357/del-nido-cardioplegia-in-adult-cardiac-surgery-beyond-single-valve-surgery
#3
Wan Kee Kim, Hong Rae Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
OBJECTIVES: In recent years, the use of del Nido (DN) cardioplegia has been reported in single-valve surgery or isolated coronary artery bypass surgery with acceptable outcomes. The reports of its use in more complex adult cardiac procedures, however, have been scarce. METHODS: We enrolled a total of 149 adult patients who underwent heart valve surgery with the use of DN cardioplegia between May 2014 and December 2016. For a benchmark comparison, 892 patients who underwent cardiac valve surgery with blood cardioplegia during the same period served as controls...
February 14, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29452208/outcome-of-abo-incompatible-adult-living-donor-liver-transplantation-for-patients-with-hepatocellular-carcinoma
#4
Young-In Yoon, Gi-Won Song, Sung-Gyu Lee, Shin Hwang, Ki-Hun Kim, Seok-Hwan Kim, Woo-Hyoung Kang, Hwui-Dong Cho, Eun-Kyoung Jwa, Jae-Hyun Kwon, Eun-Young Tak, Varvara A Kirchner
BACKGROUND & AIMS: Living-donor liver transplantation (LDLT) can simultaneously cure hepatocellular carcinoma (HCC) and underlying liver cirrhosis, improving long-term results in patients with HCC. ABO-incompatible LDLT could expand the living-donor pool, reduce waiting times for deceased-donor liver transplantation, and improve long-term survival for some patients with HCC. METHODS: We retrospectively reviewed the medical records of patients undergoing LDLT for HCC from November 2008 to December 2015 at a single institution in Korea...
February 13, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29452077/clinical-outcomes-and-factors-related-with-colonic-perforations-in-patients-receiving-self-expandable-metal-stent-insertion-for-malignant-colorectal-obstruction
#5
Yoo Jin Lee, Jin Young Yoon, Jae Jun Park, Soo Jung Park, Jie-Hyun Kim, Young Hoon Youn, Tae Il Kim, Hyojin Park, Won Ho Kim, Jae Hee Cheon
BACKGROUND AND AIMS: Although colonic perforation is a dreadful adverse event associated with stent placement, data on this topic are sparse. We aimed to investigate the clinical outcomes of colonic perforation and factors related with its occurrence in patients who receiving self-expanding metal stents (SEMSs) for malignant colorectal obstruction. METHODS: We retrospectively reviewed the data of 474 patients with malignant colorectal obstruction who received endoscopic SEMS insertion from April 2004 to May 2011 in the Severance and Gangnam Severance Hospital...
February 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29451994/stroop-task-related-brain-activity-in-patients-with-insomnia-changes-after-cognitive-behavioral-therapy-for-insomnia
#6
Jeong Yeon Hwang, Nambeom Kim, Soohyun Kim, Juhyun Park, Jae-Won Choi, Seog Ju Kim, Chang-Ki Kang, Yu Jin Lee
OBJECTIVE/BACKGROUND: In the present study, we compared differences in brain activity during the Stroop task between patients with chronic insomnia disorder (CID) and good sleepers (GS). Furthermore, we evaluated changes in Stroop task-related brain activity after cognitive-behavioral therapy for insomnia (CBT-I). PARTICIPANTS/METHODS: The final analysis included 21 patients with CID and 25 GS. All participants underwent functional magnetic resonance imaging (fMRI) while performing the color-word Stroop task...
February 16, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29450712/artifacts-during-the-arterial-phase-of-gadoxetate-disodium-enhanced-mri-multiple-arterial-phases-using-view-sharing-from-two-different-vendors-versus-single-arterial-phase-imaging
#7
Ji Hye Min, Young Kon Kim, Tae Wook Kang, Woo Kyoung Jeong, Won Jae Lee, Soohyun Ahn, Na Young Hwang
OBJECTIVES: To assess the usefulness of multiple arterial phase (AP) of gadoxetic acid-enhanced MRI using view-sharing of two different vendors to reduce transient severe motion (TSM) artifact in the AP. METHODS: This retrospective study included 298 patients (mean age 63 years) who underwent gadoxetic acid MRI with multiple AP from two different vendors; either triple (subcohort A, n=174) or quadruple (subcohort B, n=124) AP. 202 patients (143 vs. 59) underwent follow-up MRI with single AP...
February 15, 2018: European Radiology
https://www.readbyqxmd.com/read/29448728/carbon-nanostructure-of-diesel-soot-particles-emitted-from-2-and-4-stroke-marine-engines-burning-different-fuels
#8
Won-Ju Lee, Seul-Hyun Park, Se-Hyun Jang, Hwajin Kim, Sung Kuk Choi, Kwon-Hae Cho, Ik-Soon Cho, Sang-Min Lee, Jae-Hyuk Choi
Diesel soot particles were sampled from 2-stroke and 4-stroke engines that burned two different fuels (Bunker A and C, respectively), and the effects of the engine and fuel types on the structural characteristics of the soot particle were analyzed. The carbon nanostructures of the sampled particles were characterized using various techniques. The results showed that the soot sample collected from the 4-stroke engine, which burned Bunker C, has a higher degree of order of the carbon nanostructure than the sample collected from the 2-stroke engine, which burned Bunker A...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448628/functionalized-magnetic-plga-nanospheres-for-targeting-and-bioimaging-of-breast-cancer
#9
Seung-Jun Lee, Hee-Jin Kim, Yong-Min Huh, Il Won Kim, Jae Hyun Jeong, Jin-Chul Kim, Jong-Duk Kim
Superparamagnetic iron oxide nanoparticles (SPIONs) are actively used as highly sensitive imaging probes to provide contrast in MRI. In this study, we propose the use of SPIONs encapsulated with antibody-conjugated poly(lactic-co-glycolic acid) (PLGA) as a potent theragnostic agent. The SPIONs were synthesized by a chemical co-precipitation method of ferric and ferrous ions, and subsequently encapsulated with PLGA by using an emulsification-diffusion method. Herceptin was chemically conjugated to the SPION-encapsulating PLGA nanoparticles to target the human epidermal growth factor receptor 2 (Her2/neu) overexpressing breast cancers...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448610/evaluation-of-the-fitness-of-glass-infiltrated-zirconia-core-in-maxillary-central-incisor
#10
Ji-Won Kim, Gye-Jeong Oh, Hyun-Pil Lim, Kwi-Dug Yun, Chan Park, Kyung-Ku Lee, Jae-Sam Ban, Sang-Won Park, Eun-Kyung Yim
The purpose of this study was to evaluate the fitness of zirconia cores according to the amount and treated surface of glass infiltration. A maxillary right central incisor customized abutment was milled to have a 6° slope and a 1 mm deep chamfer margin and was manufactured in an intaglio mold using silicone impression material. Fifty-six stone dies were produced by injecting high strength dental stone into a mold and then zirconia cores were milled with CAD/CAM systems. The control group (Control) used non glass-infiltrated zirconia, and the experiment group was divided by one with the glass and distilled water ratio of 1:300 and the other with the ratio of 1:100...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29447923/the-significance-of-tumor-budding-in-t1-colorectal-carcinoma-the-most-reliable-predictor-of-lymph-node-metastasis-especially-in-endoscopically-resected-t1-colorectal-carcinoma
#11
So Jeong Lee, Ahrong Kim, Young Keum Kim, Won Young Park, Hyun Sung Kim, Hong-Jae Jo, Nahmgun Oh, Geum Am Song, Do Youn Park
Endoscopic resection is widely recognized as a first-line treatment for T1 colorectal cancers (CRC), although additional surgical intervention may be indicated based on the risk of lymph node (LN) metastasis. However, risk factors for LN metastasis in T1 CRC not fully established. We investigated the clinicopathological features of T1 CRC and evaluated their association with lymph node metastasis in 133 cases of T1 CRC, consisting of 87 cases with first-line endoscopic resection (EMR) followed by additional surgery and 46 cases with primary surgical resection...
February 12, 2018: Human Pathology
https://www.readbyqxmd.com/read/29447082/radiologic-measurement-of-brain-swelling-in-patients-with-large-hemispheric-infarctions-during-targeted-temperature-management
#12
Won Joo Jeong, Jae Seung Bang, Kyu Sun Yum, Sangkil Lee, Inyoung Chung, O-Ki Kwon, Chang Wan Oh, Beom Joon Kim, Hee-Joon Bae, Moon-Ku Han
Brain herniation is most often the result of severe brain swelling and can rapidly lead to death or brain death. We retrospectively identified radiologic indicators to evaluate the effects of targeted temperature management (TTM) on the extent of cerebral edema and determine the cutoff values that best predict TTM outcomes in patients with large hemispheric infarction. We retrospectively reviewed brain computed tomography (CT) scans of 21 patients with large hemispheric infarctions, who were treated with TTM...
February 15, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29443826/higher-risk-of-posttransplant-graft-failure-in-male-recipients-of-female-donor-grafts-might-not-be-due-to-anastomotic-size-disparity
#13
Kyo Won Lee, Sangbin Han, Sanghoon Lee, Hyun-Hwa Cha, Soohyun Ahn, Hyeon Seon Ahn, Justin S Ko, Mi Sook Gwak, Gaab Soo Kim, Jae-Won Joh, Suk-Koo Lee, Gyu-Seong Choi
BACKGROUND: Posttransplant liver graft failure occurs most often in male recipients of livers from female donors. The respective role of donor sex itself and the size disparity in graft vessels/bile ducts according to donor sex are unclear. Thus, we aimed to evaluate the importance of donor sex with adjustment for anastomotic size disparity between female and male donor grafts. METHODS: A total of 309 male patients without hepatic tumors who underwent living donor liver transplantation were analyzed (109 female and 200 male donors)...
February 13, 2018: Transplantation
https://www.readbyqxmd.com/read/29443737/effect-of-tenofovir-on-renal-function-in-patients-with-chronic-hepatitis-b
#14
Woo Jin Jung, Jae Young Jang, Won Young Park, Soung Won Jeong, Hee Jeong Lee, Sang Joon Park, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim, Suyeon Park, Baigal Baymbajav
Tenofovir disoproxil fumarate (TDF) is widely used to treat patients with hepatitis B virus (HBV) infection. We investigated the effect of TDF on renal insufficiency in patients with chronic hepatitis B (CHB).A consecutive cohort analysis was applied to CHB patients taking prescribed TDF from January 2012 to May 2016 at Soonchunhyang University Seoul Hospital. Alterations over time in corrected calcium, phosphate, creatinine, and estimated glomerular filtration rate (eGFR) were analyzed using the generalized estimating equation method...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29441781/flexible-and-micropatternable-triplet-triplet-annihilation-upconversion-thin-films-for-photonic-device-integration-and-anti-counterfeiting-applications
#15
Anna L Hagstrom, Hak-Lae Lee, Myung-Soo Lee, Hyun-Seok Choe, Joori Jung, Byung-Geon Park, Won-Sik Han, Jong Soo Ko, Jae-Hong Kim, Jaehyuk Kim
Triplet-triplet annihilation upconversion (TTA-UC) has recently drawn widespread interest for its capacity to harvest low-energy photons and to broaden the absorption spectra of photonic devices such as solar cells. Although conceptually promising, effective integration of TTA-UC materials into practical devices has been difficult due to the diffusive and anoxic conditions required in TTA-UC host media. Of the solid-state host materials investigated, rubbery polymers facilitate the highest TTA-UC efficiencies...
February 14, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29441757/changing-epidemiology-of-nontuberculous-mycobacterial-lung-diseases-in-a-tertiary-referral-hospital-in-korea-between-2001-and-2015
#16
Ryoung Eun Ko, Seong Mi Moon, Soohyun Ahn, Byung Woo Jhun, Kyeongman Jeon, O Jung Kwon, Hee Jae Huh, Chang Seok Ki, Nam Yong Lee, Won Jung Koh
This study investigated the changes in the major etiologic organisms and clinical phenotypes of nontuberculous mycobacterial lung disease (NTM-LD) over a recent 15-year period in Korea. The increase of number of patients with NTM-LD was primarily due to an increase of Mycobacterium avium complex (MAC) lung disease (LD). Among MAC cases, the proportion of M. avium increased compared with M. intracellulare, whereas the incidence of M. abscessus complex and M. kansasii LD remained relatively stable. The proportion of cases of the nodular bronchiectatic form increased compared with the fibrocavitary form of NTM-LD...
February 19, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29441336/a-prospective-randomized-study-comparing-radiofrequency-ablation-and-hepatic-resection-for-hepatocellular-carcinoma
#17
Hae Won Lee, Jeong Min Lee, Jung-Hwan Yoon, Yoon Jun Kim, Joong-Won Park, Sang-Jae Park, Seong Hoon Kim, Nam-Joon Yi, Kyung-Suk Suh
Purpose: Although there are several prospective clinical studies comparing radiofrequency ablation (RFA) and hepatic resection (HR) for the treatment of hepatocellular carcinoma, there are few trials that have been performed in strictly homogeneous patients. Methods: Patients who were newly diagnosed with a solitary hepatocellular carcinoma were randomized to the HR or RFA group. Inclusion criteria were as follows: age ≥ 20 years but ≤ 70 years, Child-Pugh class A, maximal diameter of the tumor ≥ 2 cm but ≤ 4 cm, no previous treatment history, and platelet count > 80,000/mm 3 ...
February 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29438754/mno-2-deposited-lignin-based-carbon-nanofiber-mats-for-application-as-electrodes-in-symmetric-pseudocapacitors
#18
Won-Jae Youe, Seok Ju Kim, Soo-Min Lee, Sang-Jin Chun, Juwon Kang, Yong Sik Kim
Low-cost, high-performance electrodes are highly attractive for practical supercapacitor applications. MnO2-deposited carbon nanofiber mats (MnO2-CNFMs) are prepared for use as binder-free supercapacitor electrodes. MnO2is deposited on the mats in situ by hydrothermally decomposing aqueous KMnO4, leading to the formation of nanocrystals of MnO2. The MnO2-CNFM electrode produced with 38.0 μmol KMnO4(this electrode) shows a high specific capacitance of ~171.6 F·g-1at a scan rate of 5 mV·s-1. Moreover, a symmetric supercapacitor with the electrode exhibits a specific capacitance of 67...
February 10, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29436651/identification-of-bioactive-heterocyclic-compounds-from-mulberry-and-their-protective-effect-against-streptozotocin-induced-apoptosis-in-ins-1-cells
#19
Ji Hoon Song, Dahae Lee, Seoung Rak Lee, Jae Sik Yu, Tae Su Jang, Joo-Won Nam, Ki Hyun Kim, Ki Sung Kang
A phytochemical investigation of the MeOH extracts from mulberries (the fruit of Morus alba L.) led to the identification of six heterocyclic compounds (1‑6). These compounds were screened to detect whether they protected pancreatic INS‑1 cells from streptozotocin (STZ)‑induced cytotoxicity. Compound 3 was the most effective at preventing STZ‑induced cytotoxicity and the production of reactive oxygen species (ROS) in INS‑1 cells. In addition, compound 3 effectively prevented apoptosis induced by STZ in INS‑1 cells...
February 8, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29436586/amelioration-of-inflammatory-responses-by-socheongryong-tang-a-traditional-herbal-medicine-in-raw-264-7%C3%A2-cells-and-rats
#20
Sang Mi Park, Tae Hoon Lee, Rongjie Zhao, Youn Sook Kim, Ji Yun Jung, Chung A Park, Kyung Hwan Jegal, Sae Kwang Ku, Jae Kwang Kim, Chul Won Lee, Young Woo Kim, Il Je Cho, Won G An, Sang Chan Kim
Socheongryong-Tang (SCRT) is a natural medicine prescription that has been mainly used in East Asia for the treatment of inflammatory disorders, including asthma and allergic rhinitis. The present study evaluated the anti-inflammatory effects of SCRT on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and in a rat model of carrageenan (CA)-induced paw edema. Levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6 and prostaglandin E2 (PGE2) in the culture supernatant were quantified and nitric oxide (NO) production was monitored...
February 6, 2018: International Journal of Molecular Medicine
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