Ashley N Battarbee, Lisa Mele, Mark B Landon, Michael Varner, Brian M Casey, Uma Reddy, Ronald Wapner, Dwight J Rouse, John M Thorp, Edward Chien, George Saade, Alan Peaceman, Sean C Blackwell
OBJECTIVE: To measure the association between hypertensive disorders of pregnancy (HDP) and long-term maternal metabolic and cardiovascular biomarkers. STUDY DESIGN: Follow-up study of patients who completed glucose tolerance testing 5-10 years after enrollment in a mild GDM treatment trial or concurrent non-GDM cohort. Maternal serum insulin concentrations and cardiovascular markers VCAM-1, VEGF, CD40L, GDF-15 and ST-2 were measured, and insulinogenic index (IGI, pancreatic -cell function) and 1/HOMA (insulin resistance) were calculated...
May 18, 2023: American Journal of Perinatology