keyword
https://read.qxmd.com/read/38511752/a-retrospective-study-of-pregnant-patients-with-acute-pancreatitis
#1
JOURNAL ARTICLE
Şehmus Ölmez, Bünyamin Sarıtaş, Mehmet Suat Yalçın, Raziye Narin, Adnan Taş, Nevin Akçaer Öztürk, Mustafa Muslu, Haşim Nar, Ekrem Sapmaz, Banu Kara
OBJECTIVE: Acute pancreatitis is a rare disease in pregnant patients. Although it may have serious maternal and fetal consequences, morbidity and mortality rates have decreased recently due to appropriate and rapid treatment with earlier diagnosis. The aim of this study was to evaluate pregnant patients diagnosed with acute pancreatitis. METHODS: The study included pregnant patients diagnosed with acute pancreatitis who were admitted to Adana City Training and Research Hospital in Adana, Turkey, between January 2014 and January 2022...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38465073/key-components-of-successful-management-of-acute-fatty-liver-of-pregnancy-a-case-report-and-literature-review
#2
Rekha Patidar, Krishi Gowdra Revannasiddappa, Muniza Ghazanfer
Acute fatty liver of pregnancy (AFLP) is a rare, potentially fatal obstetric emergency. Due to its nonspecific signs and symptoms, there is often a delay in diagnosis and management which is associated with morbid complications and high mortality. We report a case of a 30-year-old female gravida 3 para 2 at 32 weeks gestation who presented with nausea and vomiting for two weeks, pruritis for three days, and upper abdomen pain for a day. A clinical diagnosis of HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome/obstetric cholestasis/AFLP was made...
February 2024: Curēus
https://read.qxmd.com/read/38443883/therapeutic-plasma-exchange-decreases-serum-triglyceride-level-rapidly-and-reduces-early-recurrence-rate-but-no-advantages-in-improving-outcomes-for-patients-with-hyperlipidemic-acute-pancreatitis-a-retrospective-propensity-score-matching-analysis-based-on
#3
JOURNAL ARTICLE
Canbin Zheng, Yongping Zheng, Zihui Zheng
BACKGROUND: Hyperlipidaemic acute pancreatitis (HLAP) has become the most common cause of acute pancreatitis (AP) not due to gallstones or alcohol (Mosztbacher et al, Pancreatology 20:608-616, 2020; Yin et al, Pancreas 46:504-509, 2017). Therapeutic plasma exchange (TPE) has been reported to be effective in reducing serum TG levels which is important in management of HLAP (World J Clin Cases 9:5794-803, 2021). However, studies on TPE are mostly focusing on cases reports, TPE remains poorly evaluated till date and need to be compared with conservative therapy with a well-designed study...
March 6, 2024: BMC Endocrine Disorders
https://read.qxmd.com/read/38391228/clinical-characteristics-and-pregnancy-outcome-analysis-of-20-cases-of-acute-pancreatitis-during-pregnancy
#4
JOURNAL ARTICLE
Dong Zhou, Guoqiang Sun, Jing Hu, Quan Gan
OBJECTIVE: This study investigated the clinical characteristics and pregnancy outcomes of acute pancreatitis during pregnancy (APIP). METHODS: A retrospective analysis was conducted on 20 cases of APIP admitted to Hubei Maternal and Child Health Hospital from January 2017 to September 2021. The etiology, clinical manifestations, and perinatal outcomes of APIP were analyzed using descriptive statistical analysis of the collected data. RESULTS: The incidence of APIP in our hospital was 20 (0...
February 23, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38334943/genetic-factors-associated-with-adverse-pregnancy-outcomes-in-chronic-pancreatitis
#5
JOURNAL ARTICLE
Di Wu, Nan Ru, Yuan-Chen Wang, Guo-Xiu Ma, Tian-Yu Shi, Si-Huai Xiong, Ai-Jun You, Lei Wang, Liang-Hao Hu, Zhao-Shen Li, Wen-Bin Zou, Zhuan Liao
OBJECTIVES: The effects of genetic factors on pregnancy outcomes in chronic pancreatitis (CP) patients remain unclear. We evaluated the impacts of clinical features and mutations in main CP-susceptibility genes (SPINK1, PRSS1, CTRC, CFTR) on pregnancy outcomes in Chinese CP patients. METHODS: This was a prospective cohort study with 14-year follow-up. The sample comprised female CP patients with documented pregnancy and known genetic backgrounds. Adverse pregnancy outcomes were compared between patients with and without gene mutations...
February 9, 2024: Clinical and Translational Gastroenterology
https://read.qxmd.com/read/38304305/pregnant-patients-undergoing-cholecystectomy-nationwide-assessment-of-clinical-characteristics-and-outcomes
#6
JOURNAL ARTICLE
Genevieve R Mazza, Ariane C Youssefzadeh, Laurel S Aberle, Zachary S Anderson, Rachel S Mandelbaum, Joseph G Ouzounian, Kazuhide Matsushima, Koji Matsuo
BACKGROUND: Gallstone disease in pregnancy is one of the most common indications for nonobstetrical surgery during pregnancy. National-level data on contemporary surgical practice and outcomes are limited. OBJECTIVE: This study aimed to assess the clinical characteristics and outcomes of patients undergoing cholecystectomy during pregnancy. STUDY DESIGN: This cross-sectional study examined the Healthcare Cost and Utilization Project's 2 nationwide databases in the United States: the National Inpatient Sample and the Nationwide Ambulatory Surgery Sample...
February 2024: AJOG global reports
https://read.qxmd.com/read/38282454/a-bumpy-ride-acute-recurrent-pancreatitis-in-pregnancy-in-a-type-2-diabetic-presenting-with-euglycemic-diabetic-ketoacidosis-a-case-report
#7
JOURNAL ARTICLE
Sara Showkath Ali, Sowrabha Bhat, Hisham A Salih, Ansaba Naseer, Annie Rajaratnam
No abstract text is available yet for this article.
January 28, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38269492/metformin-adverse-event-profile-a-pharmacovigilance-study-based-on-the-fda-adverse-event-reporting-system-faers-from-2004-to-2022
#8
JOURNAL ARTICLE
Yikuan Du, Jinfeng Zhu, Zhuoming Guo, Zhenjie Wang, Yuni Wang, Mianda Hu, Lingzhi Zhang, Yurong Yang, Jinjin Wang, Yixing Huang, Peiying Huang, Mianhai Chen, Bo Chen, Chun Yang
BACKGROUND: Metformin has the potential for treating numerous diseases, but there are still many unrecognized and unreported adverse events (AEs). METHODS: We selected data from the United States FDA Adverse Event Reporting System (FAERS) database from the first quarter (Q1) of 2004 to the fourth quarter (Q4) of 2022 for disproportionality analysis to assess the association between metformin and related adverse events. RESULTS: In this study 10,500,295 case reports were collected from the FAERS database, of which 56,674 adverse events related to metformin were reported...
January 25, 2024: Expert Review of Clinical Pharmacology
https://read.qxmd.com/read/38249273/acute-gallstone-pancreatitis-in-pregnancy-a-multidisciplinary-approach
#9
Mark Ayoub, Muhammed Ceesay, Carol Faris, Michael Iannetti
A common cause of gastrointestinal-related hospitalizations in the United States of America is acute pancreatitis (AP), with an annual incidence of up to 80 cases per 100,000 people. The incidence of AP in pregnancy varies and is approximately 1 in 1000 to 1 in 10,000 births due to the prevalence of obesity and gallstone-related conditions. Deciding on the timing of surgical intervention in acute biliary pancreatitis during pregnancy remains challenging, and there are no consensus recommendations. Gallstone pancreatitis has a high recurrence rate of up to 50% during the first trimester...
December 2023: Curēus
https://read.qxmd.com/read/38249199/pregnancy-with-diabetic-ketoacidosis-and-hypertriglyceridemia-induced-acute-pancreatitis-the-enigmatic-triad
#10
Nibedita Mishra
Acute pancreatitis in pregnancy is a rare condition. Acute pancreatitis due to hypertriglyceridemia in a case of diabetic ketoacidosis is also a very rare condition with a very high mortality rate. Here, we report a case of a 34-week pregnancy with pregnancy-induced hypertension, diabetic ketoacidosis, and hypertriglyceridemia-induced acute pancreatitis with underlying gallstone disease, which might have contributed to the etiology of pancreatitis. There is no report of such a case in the available literature...
December 2023: Curēus
https://read.qxmd.com/read/38222172/mucinous-cystic-neoplasm-of-the-pancreas-in-pregnancy-a-case-report
#11
Khalid Al Shamousi, Said A Al-Busafi, Masoud Kashoob, Adil Al Zadjali, Hoor Al Kaabi
Mucinous cystic neoplasms (MCNs) of the pancreas are rare epithelial neoplasms, characterized by an inner epithelial layer and an ovarian-type sub-epithelial stroma. These lesions are typically benign but can pose challenges during pregnancy due to their rapid growth potential, associated risk of malignant transformation, and complications such as pancreatitis. We present a case of a 39-year-old pregnant female with a history of recurrent acute pancreatitis, diagnosed with an MCN during pregnancy. Diagnostic procedures were deferred until after delivery, followed by successful distal pancreatectomy...
December 2023: Curēus
https://read.qxmd.com/read/38186520/laparoscopic-cholecystectomy-in-pregnancy-a-seven-year-retrospective-study-from-an-australian-tertiary-center
#12
JOURNAL ARTICLE
Xinyi Nan, Erick Chan, Kok Sum Chloe Wong, Justin Ng, Sara Izwan, Michelle Cooper, Ramesh Damodaran
Background Cholecystectomy is the second most common non-obstetric indication for surgery during pregnancy; however, there is little recent literature specifically exploring perioperative care approaches, and a paucity of Australian data exists. This study investigates the incidence of laparoscopic cholecystectomy (LC) during pregnancy, peri-operative management, and post-operative outcomes in a single Australian tertiary center. Methods A retrospective analysis of LCs performed on pregnant patients between the ages of 16 and 50 years at a tertiary hospital between 2016 and 2023 was completed...
December 2023: Curēus
https://read.qxmd.com/read/38095394/the-value-of-neutrophil-to-lymphocyte-ratio-platelet-to-lymphocyte-ratio-red-cell-distribution-width-and-their-combination-in-predicting-acute-pancreatitis-severity
#13
JOURNAL ARTICLE
H H Vo, N N Truong-Thi, H B Ho-Thi, H M C Vo, K T Tran-Thi, M D Nguyen
OBJECTIVE: Acute pancreatitis is one of the most common causes of acute abdominal pain requiring hospitalization worldwide. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and red blood cell distribution width (RDW) are novel inflammatory markers that have been investigated in various diseases associated with an inflammatory response, achieving many positive results. Evaluating the NLR, PLR, RDW, and their combination to predict acute pancreatitis severity can help clinicians have an appropriate initial treatment strategy...
December 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38023361/treatment-and-diagnosis-of-hyperlipidemia-acute-pancreatitis-in-pregnancy-associated-with-pre%C3%A2-pregnancy-obesity-and-diabetes-a-case-report
#14
Weiping Cao, Xia Ni, Mengwen Gan, Bing Xie, Yurong Xie, Qin Wang, Lishi Meng, Chao He, Juan Chen, Xinzhi Wang
Hyperlipidemia acute pancreatitis (HLAP) is a specific type of pancreatitis mainly caused by elevated serum triglyceride (TG) levels. Therefore, knowledge of patients' medical history is crucial to the identification of those at high risk of HLAP. Diabetes and obesity are associated with high levels of triglycerides, a risk factor for the development of HLAP, which should be controlled before pregnancy. Moreover, HLAP is associated with additional diagnostic and management challenges related to hyperlipidemia (HL) and pregnancy...
December 2023: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/37920254/case-report-abruptio-placentae-and-epileptic-seizure-after-occurrence-of-perinatal-hyperglycaemia-in-woman-with-gestational-diabetes-mellitus-and-hypertriglyceridemia-induced-acute-pancreatitis
#15
Yanlang He, Zhijie Huang, Changli Wei, Jianyong Chen
Hypertriglyceridemia-induced acute pancreatitis seldom occurs in the second trimester of pregnancy with gestational diabetes mellitus. For these patients, the existing knowledge on concomitant hyperglycemia is not sufficient. We report a case of abruptio placentae and epileptic seizure following perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis. The occurrence of abruptio placentae and epileptic seizure may be associated with concomitant hyperglycemia, and the epileptic seizure was terminated after she underwent treatment with insulin...
2023: Frontiers in Endocrinology
https://read.qxmd.com/read/37915236/acute-cholecystitis-in-pregnant-women-a-therapeutic-challenge-in-a-developing-country-center
#16
JOURNAL ARTICLE
Mohamed Fares Mahjoubi, Anis Ben Dhaou, Mohamed Maatouk, Nada Essid, Bochra Rezgui, Yasser Karoui, Mounir Ben Moussa
BACKGROUNDS/AIMS: Acute cholecystitis is a rare condition in pregnant women, potentially affecting the maternal and fetal prognosis. Our aim was to report the main clinical and paraclinical features of acute cholecystitis during pregnancy and therapeutic modalities. METHODS: We conducted a case series analysis recording pregnant patients with acute cholecystitis admitted to our surgery department over a period of 11 years. We collected clinical data, paraclinical features, and management modalities related to cholecystitis...
November 2, 2023: Annals of Hepato-Biliary-Pancreatic Surgery
https://read.qxmd.com/read/37868279/the-association-of-polish-surgeons-aps-clinical-guidelines-for-the-use-of-laparoscopy-in-the-management-of-abdominal-emergencies-part-ii
#17
JOURNAL ARTICLE
Jacek Sobocki, Michał Pędziwiatr, Justyna Bigda, Wacław Hołówko, Piotr Major, Kryspin Mitura, Piotr Myśliwiec, Małgorzata Nowosad, Aneta Obcowska-Hamerska, Michał Orłowski, Monika Proczko-Stepaniak, Jacek Szeliga, Grzegorz Wallner, Marek Zawadzki
INTRODUCTION: Over the past three decades, almost every type of abdominal surgery has been performed and refined using the laparoscopic technique. Surgeons are applying it for more procedures, which not so long ago were performed only in the classical way. The position of laparoscopic surgery is therefore well established, and in many operations it is currently the recommended and dominant method. AIM: The aim of the preparation of these guidelines was to concisely summarize the current knowledge on laparoscopy in acute abdominal diseases for the purposes of the continuous training of surgeons and to create a reference for opinions...
September 2023: Videosurgery and Other Miniinvasive Techniques
https://read.qxmd.com/read/37851097/maternal-and-fetal-outcomes-of-acute-pancreatitis-in-pregnancy-a-population-based-study
#18
JOURNAL ARTICLE
Chengu Niu, Jing Zhang, Hongli Liu, Kaiwen Zhu, Patrick I Okolo
BACKGROUND: Acute pancreatitis during pregnancy can have negative effects on both the mother and the fetus. The primary aim of this study is to evaluate the trends, maternal and fetal outcomes, and associated comorbidities of acute pancreatitis during pregnancy using data from the USA National Inpatient Sample (NIS) database. METHODS: This study is a retrospective analysis of hospital discharge records from the NIS database from 2009 to 2019. RESULTS: Delivery patients with acute pancreatitis faced a higher risk of maternal mortality (AOR 91...
October 18, 2023: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/37789261/the-role-of-apheresis-and-insulin-therapy-in-hypertriglyceridemic-acute-pancreatitis-a-concise-review
#19
REVIEW
Jakob Gubensek
Severe hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP) and is involved in its pathogenesis. Chylomicrons increase blood viscosity and induce ischemia, while free fatty acids induce inflammation and distant organ damage. Conservative treatment options include fasting and insulin; limited evidence shows their comparable efficacy. Plasma exchange might provide more rapid lowering of triglycerides and amelioration of systemic effects of severe AP. Available data from controlled studies show only moderately faster lowering of triglycerides with apheresis (about 70% vs...
October 3, 2023: BMC Gastroenterology
https://read.qxmd.com/read/37741950/risk-of-complications-after-endoscopic-retrograde-cholangiopancreatography-in-pregnancy-a-propensity-matched-analysis
#20
JOURNAL ARTICLE
Dushyant Singh Dahiya, Saurabh Chandan, Aakash Desai, Daryl Ramai, Babu P Mohan, Antonio Facciorusso, Mohammad Bilal, Neil R Sharma, Douglas G Adler, Gursimran S Kochhar
BACKGROUND: Studies have suggested higher complication rates after endoscopic retrograde cholangiopancreatography (ERCP) in pregnancy. AIMS: We performed a propensity-matched cohort analysis to assess the risk of ERCP-related complications among pregnant women in the United States. METHODS: The TriNetX database was analyzed to identify pregnant and non-pregnant females between 18 and 50 years of age who underwent ERCP. One-to-one propensity score matching was performed for age and race...
September 24, 2023: Digestive Diseases and Sciences
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