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https://www.readbyqxmd.com/read/29772932/recent-advances-in-kartogenin-for-cartilage-regeneration
#1
Gaorui Cai, Wei Liu, Yong He, Jianghong Huang, Li Duan, Jianyi Xiong, Lijun Liu, Daping Wang
Either osteoarthritisor sports-related injuries can lead to cartilage defects,whereas both chondrocyte self-renewal and conventional treatments face limitations. In cartilage regenerative medicine, growth factors are commonly used to induce chondrogenic differentiation of stem cells. However, application of growth factors is confined by some drawbacks. Emerging small molecules are regarded as an alternative for cartilage regeneration. A recently discovered small-molecule compound, kartogenin (KGN), has been proven to be a chondrogenic and chondroprotective agent and is more effective in inducing cartilage regeneration when compared with growth factors...
May 18, 2018: Journal of Drug Targeting
https://www.readbyqxmd.com/read/29772188/hamstring-and-ankle-flexibility-deficits-are-weak-risk-factors-for-hamstring-injury-in-professional-soccer-players-a-prospective-cohort-study-of-438-players-including-78-injuries
#2
Nicol van Dyk, Abdulaziz Farooq, Roald Bahr, Erik Witvrouw
BACKGROUND: Hamstring injuries remain a significant injury burden in sports such as soccer that involve high-speed running. It has repeatedly been identified as the most common noncontact injury in elite male soccer, representing 12% of all injuries. As the incidence of hamstring injuries remains high, investigations are aimed at better understanding how to prevent hamstring injuries. Stretching to improve flexibility is commonly used in elite-level sports, but risk factor studies have reported contradicting results, leading to unclear conclusions regarding flexibility as a risk factor for hamstring injuries...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29764877/efficacy-of-practising-tai-chi-for-older-people-with-mild-dementia-protocol-for-a-randomised-controlled-study
#3
Jihui Lyu, Wenjie Li, Xiangjiang Rong, Lian Wei, Nayan Huang, Mei Champ, Qian Xiong, Xueli Chen, Mo Li, Fangling Li
INTRODUCTION: Many studies suggest that Tai Chi exercise is a safe and appropriate mind-body exercise for older people and effectively slows down age-related cognitive decline. A set of bespoke Tai Chi exercise named 'Cognition Protecting Tai Chi' (CPT) has been created for older people with cognitive impairments by the research team of geriatricians, neurologists, rehabilitation specialists, experts of sports medicine and experienced practitioners of traditional Chinese medicine. This trial is designed to evaluate its effects on cognitive function, behaviour/moods, risk of falls and activities of daily living of the participants with mild dementia...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29761651/mr%C3%AF-inside-the-meat-pie
#4
John Massie, Michael Kean, Tim Cain
Meat pies have been adopted as one of Australia's favourite foods, and considered an icon by many. The hand-held convenience of the pie has made them a culinary necessity while watching sport, also beloved in Australia. An enduring question about the meat pie is what exactly is inside. This can be difficult to ascertain by digital, ocular or oral exploration. In this study we use MR imaging to study the contents of some of Australia's best loved pies.
May 14, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29750318/return-to-play-after-patellar-stabilization
#5
REVIEW
Seth L Sherman, Daniel P Deasis, Andrew J Garrone, Elliott E Voss, Harvey A Oliver
PURPOSE OF REVIEW: The purpose of this review is to evaluate the existing literature regarding return to play (RTP) and return to prior performance (RPP) following patellar stabilization surgery. It will also discuss suggested guidelines regarding RTP, and finally, to encourage future patellofemoral instability research to report and publish results of RTP rates using standardized RTP guidelines. RECENT FINDINGS: There is a lack of validation and universal adoption of standardized RTP guidelines...
May 10, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29740341/circulating-mirnas-as-putative-biomarkers-of-exercise-adaptation-in-endurance-horses
#6
Katia Cappelli, Stefano Capomaccio, Andrea Viglino, Maurizio Silvestrelli, Francesca Beccati, Livia Moscati, Elisabetta Chiaradia
Endurance exercise induces metabolic adaptations and has recently been reported associated with the modulation of a particular class of small noncoding RNAs, microRNAs, that act as post-transcriptional regulators of gene expression. Released into body fluids, they termed circulating miRNAs, and they have been recognized as more effective and accurate biomarkers than classical serum markers. This study examined serum profile of miRNAs through massive parallel sequencing in response to prolonged endurance exercise in samples obtained from four competitive Arabian horses before and 2 h after the end of competition...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29736693/feasibility-testing-of-hydrophobic-carbon-electrodes-for-acquisition-of-underwater-surface-electromyography-data
#7
Hugo Posada-Quintero, Yeonsik Noh, Caitlin Eaton-Robb, John P Florian, Ki H Chon
Underwater surface electromyography (sEMG) signals are especially of interest for rehabilitation and sports medicine applications. Silver/silver chloride (Ag/AgCl) hydrogel electrodes, although the gold standard for sEMG data collection, require waterproofing for underwater applications. Having to apply waterproof tape over electrodes impedes the deployment of sEMG in immersed conditions. As a better alternative for underwater applications, we have developed carbon black/polydimethylsiloxane (CB/PDMS) electrodes for collecting sEMG signals under water...
May 7, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29731951/advanced-computational-methods-in-bio-mechanics
#8
REVIEW
Waleed M S Al Qahtani, Mohamed I El-Anwar
A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions more accurately and with fewer traumas, computer-integrated surgery (CIS) systems could help to improve clinical outcomes and the efficiency of healthcare delivery. CIS systems could have a similar impact on surgery to that long since realised in computer-integrated manufacturing...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29729754/editorial-commentary-outcomes-reporting-in-value-based-care-it-s-complicated
#9
EDITORIAL
Nikhil N Verma
Patient-reported outcomes have received increasing attention as a tool to measure physician performance and value in health care. Lack of standardization, cost, and patient compliance remain significant barriers to the widespread acceptance of patient-reported outcomes in orthopaedic sports medicine.
May 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29727597/cardiovascular-health-profile-among-qu%C3%A3-bec-male-and-female-police-officers
#10
Philippe Gendron, Claude Lajoie, Louis Laurencelle, François Trudeau
PURPOSE: To document the cardiovascular health profile of Québec police officers (PO). METHODS: Participants answered an online questionnaire evaluating the presence of cardiovascular disease (CVD) risk factors and symptoms. RESULTS: Two thousand, ninety-nine (2,099) male (age: 40.8 ± 9.2 years) and 756 female (age: 37.9 ± 7.9 years) PO participated in this study. The prevalence of obesity (body mass index ≥ 30░kg/m2 ) and diagnosed hypertension was respectively 21...
May 4, 2018: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/29724137/pursuit-of-proteomic-excellence-and-the-excitement-in-ko%C3%A5-ice-slovakia-at-the-11th-central-and-eastern-european-proteomic-conference-ceepc
#11
Suresh Gadher, Mangesh Bhide, Hana Kovarova
The Central and Eastern European Proteomic Conference (CEEPC) successfully launched its second decade of proteomics in Košice, Slovakia with a program of systems biology, cellular, clinical, veterinary and sports proteomics. Whilst many conferences are struggling to attract participants, CEEPC with its outstanding track record and unique 'family - feel' packaged with excellent ambiance is thriving and bringing together proteomics experts from academia, industry, scientific specialties, clinics and precision medicine communities interested in resolving mysteries about protein functionalities in health and disease...
May 4, 2018: Expert Review of Proteomics
https://www.readbyqxmd.com/read/29723136/the-history-of-aerobics-50-years-and-still-counting
#12
Kenneth H Cooper
Looking back over the 50 years since Aerobics was published, I could never have expected for there to have been a major change in physicians' attitudes toward the value of exercise in the practice of medicine. In my lifetime, I never thought I would see a stress test be considered a mandatory component of a complete examination, inactivity classified as importantly as high blood pressure and high cholesterol, and cigarette smoking considered a coronary risk factor. I have tried in this Research Quarterly for Exercise and Sport (RQES) Lecture presentation to document how this slow but gradual transition took place due to my work and the work of many of my colleagues in this field, along with the important work of The Cooper Institute...
May 3, 2018: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29722761/biological-therapies-in-orthopedic-sports-medicine
#13
Nicola Maffulli, F Alan Barber
No abstract text is available yet for this article.
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722578/a-review-of-prevention-diagnosis-and-treatment-of-relative-energy-deficiency-in-sport-red-s-in-artistic-synchronized-swimming
#14
Sherry Robertson, Margo Mountjoy
The syndrome Relative Energy Deficiency in Sport (RED-S) is a clinical entity characterized by low energy availability (LEA), which can negatively affect the health and performance of both male and female athletes. The underlying mechanism of RED-S is an inadequacy of dietary energy to support optimal health and performance. This syndrome refers to impaired physiological function including metabolic rate, menstrual function, bone health, immunity, protein synthesis, and cardiovascular health, with psychological consequences which can either precede (through restrictive dietary habits) or result from RED-S...
May 3, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29722373/chemical-formation-of-soft-metal-electrodes-for-flexible-and-wearable-electronics
#15
REVIEW
Dongrui Wang, Yaokang Zhang, Xi Lu, Zhijun Ma, Chuan Xie, Zijian Zheng
Flexible and wearable electronics is one major technology after smartphones. It shows remarkable application potential in displays and informatics, robotics, sports, energy harvesting and storage, and medicine. As an indispensable part and the cornerstone of these devices, soft metal electrodes (SMEs) are of great significance. Compared with conventional physical processes such as vacuum thermal deposition and sputtering, chemical approaches for preparing SMEs show significant advantages in terms of scalability, low-cost, and compatibility with the soft materials and substrates used for the devices...
May 3, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29720477/picking-the-right-tools-for-the-job-opening-up-the-statistical-toolkit-to-build-a-compelling-case-in-sport-and-exercise-medicine-research
#16
EDITORIAL
Johann Windt, Rasmus Oestergaard Nielsen, Bruno D Zumbo
No abstract text is available yet for this article.
May 2, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29715216/sports-related-concussions-in-children-differences-in-care-and-expectations-when-seen-in-an-emergency-department-versus-a-sports-medicine-clinic
#17
Kraigher Allan OʼKeefe, Bradley Beamon, Kori L Brewer, Brock Niceler
OBJECTIVES: Patient and parent expectations can potentially influence management of care. We compared expectations in the diagnosis of concussion between patients who presented to a pediatric emergency department (ED) and those who presented to a sports medicine clinic, and if there was a difference in computed tomography (CT) scans performed. METHODS: Head-injured athletes aged 8 to 18 years presenting to a pediatric ED and a sports medicine clinic were enrolled...
May 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29698295/not-the-last-word-a-goldwater-rule-for-sports-medicine
#18
Joseph Bernstein
No abstract text is available yet for this article.
April 24, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29694677/interseason-variability-in-isokinetic-strength-and-poor-correlation-with-nordic-hamstring-eccentric-strength-in-football-players
#19
Nicol van Dyk, Erik Witvrouw, Roald Bahr
INTRODUCTION: In elite sport, the use of strength testing to establish muscle function and performance is common. Traditionally, isokinetic strength tests have been used, measuring torque during concentric and eccentric muscle action. A device that measures eccentric hamstring muscle strength while performing the Nordic hamstring exercise is now also frequently used. The study aims to investigate the variability of isokinetic muscle strength over time, e.g. between seasons, and the relationship between isokinetic testing and the new Nordic hamstring exercise device...
April 25, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29692203/a-new-generalized-cycle-ergometry-equation-for-predicting-maximal-oxygen-uptake-the-fitness-registry-and-the-importance-of-exercise-national-database-friend
#20
Peter Kokkinos, Leonard A Kaminsky, Ross Arena, Jiajia Zhang, Jonathan Myers
Background To develop a clinically applicable equation derived from direct assessment of maximal oxygen uptake (VO2max ) to predict VO2max assessed indirectly during cycle ergometry. Design VO2max was assessed by open-circuit spirometry during a graded maximal exercise test using cycle ergometry. Multivariable linear regression analysis was applied to identify the most relevant variables and construct the best prediction model for VO2max using a random sample of 70% from each of the following age categories: <40, 40-50, 50-70 and >70 years; the remaining 30% was used for validation...
January 1, 2018: European Journal of Preventive Cardiology
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