Monica L Reynolds, Andrea L Oliverio, Jarcy Zee, Elizabeth M Hendren, Michelle M O'Shaughnessy, Isabelle Ayoub, Salem Almaani, Tetyana L Vasylyeva, Katherine E Twombley, Shikha Wadhwani, Julia M Steinke, Dana V Rizk, Meryl Waldman, Margaret E Helmuth, Carmen Avila-Casado, Nada Alachkar, Carla M Nester, Vimal K Derebail, Michelle A Hladunewich, Laura H Mariani
INTRODUCTION: Preeclampsia increases the risk for future chronic kidney disease (CKD). Among those diagnosed with CKD, it is unclear whether a prior history of preeclampsia, or other complications in pregnancy, negatively impact kidney disease progression. In this longitudinal analysis, we assessed kidney disease progression among women with glomerular disease with and without a history of a complicated pregnancy. METHODS: Adult women enrolled in the Cure Glomerulonephropathy study (CureGN) were classified based on a history of a complicated pregnancy (defined by presence of worsening kidney function, proteinuria, or blood pressure; or a diagnosis of preeclampsia, eclampsia, or hemolysis, elevated liver enzymes, and low platelets [HELLP] syndrome), pregnancy without these complications, or no pregnancy history at CureGN enrollment...
April 2023: KI Reports