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preeclampsia eclampsia hellp

D Mannaerts, E Faes, J Gielis, J Briedé, P Cos, E Van Craenenbroeck, W Gyselaers, J Cornette, M Spaanderman, Y Jacquemyn
AIMS: Oxidative stress is crucial in the pathophysiology of preeclampsia. Reactive oxygen species (ROS) like the superoxide radical O2-, are produced by the ischemic placenta, causing systemic inflammation and endothelial dysfunction. EPR uses microwave radiation and a high magnetic field and is the most direct and reliable method to detect free radicals. We explored the feasibility of determining O2- concentration in maternal serum and compared pre-eclamptic and uncomplicated pregnancies...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
Betül Başaran, Bilge Çelebioğlu, Ahmet Başaran, Seher Altınel, Leyla Kutlucan, James N Martin
OBJECTIVE: Substantial controversy exists regarding anesthetic management for patients with preeclampsia or hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome. Experts, researchers, clinicians, and residents in Turkey were surveyed about their practices. MATERIAL AND METHODS: Questionnaires were distributed to attendees at a national conference, and they were filled out immediately. Anonymous 10-item paper surveys were administered to both residents and non-residents...
2016: Journal of the Turkish German Gynecological Association
Sangeethapriya Duraiswamy, Jeanne S Sheffield, Donald Mcintire, Kenneth Leveno, Marlyn J Mayo
BACKGROUND: The most common cause of jaundice during pregnancy in the United States (US) is still attributed to viral hepatitis, despite the dramatic drop in incidence of viral hepatitis in the US. OBJECTIVE: We hypothesized that viral hepatitis is no longer a frequent etiology of jaundice among the pregnant population in the US and sought to identify the contemporary causes of elevated bilirubin during pregnancy as well as to quantify the associated risk to the mother and fetus...
September 1, 2016: Digestive Diseases and Sciences
Annettee Nakimuli, Sarah Nakubulwa, Othman Kakaire, Michael Odongo Osinde, Scovia Nalugo Mbalinda, Nelson Kakande, Rose Chalo Nabirye, Dan Kabonge Kaye
BACKGROUND: Hypertensive disorders of pregnancy are a major cause of morbidity and mortality. The objective was to estimate the disease burden attributable to hypertensive disorders of pregnancy in two referral hospitals in Uganda. METHODS: Through a prospective cohort study conducted in Jinja and Mulago hospitals in Uganda from March 1, 2013 and February 28, 2014, hypertension-related cases were analyzed. Maternal near miss cases were defined according to the WHO criteria...
2016: BMC Pregnancy and Childbirth
Jean-Pierre Fauvel
Hypertension in pregnancy has several forms that differ by their mechanisms and their consequences for mothers and fetus. Chronic hypertension is defined by SBP≥140mm Hg or DBP≥90mm Hg before pregnancy or before the 20th week of amenorrhea. Gestational hypertension is defined by SBP≥140mm Hg or DBP≥90mm Hg during or after the 20th week of amenorrhea. Preeclampsia is the occurrence of hypertension and proteinuria after 20weeks of amenorrhea. Severe preeclampsia is accompanied by clinical signs and symptoms indicating visceral pain...
July 2016: La Presse Médicale
D SocolIov, C Ilea, I Anghelache Lupascu, I Blidaru, A Luca, M Radescu, A Carauleanu, R Socolov
PURPOSE OF INVESTIGATION: The purpose of this study was to evaluate the maternal and perinatal outcome and prognosis in pregnant women with HELLP syndrome. MATERIALS AND METHODS: Medical records of eligible pregnant women with HELLP syndrome were reviewed retrospectively. Patients were evaluated in terms of maternal complication, as well as the types of delivery. Perinatal outcome were evaluated in terms ofApgar score, birth weight, respiratory distress syndrome, and neonatal intensive care unit admission...
2016: Clinical and Experimental Obstetrics & Gynecology
J G Vázquez-Rodríguez, C D Ríos-Gutiérrez, E P Paredes-Lozano, A García-Flores
BACKGROUND: HELLP syndrome is an aggressive form of preeclampsia related with hemolysis and its complications. OBJECTIVE: To determine the frequency of the appearance of criteria of hemolysis and maternal complications in preeclamptic patients with HELLP syndrome treated in an intensive care unit. MATERIAL AND METHODS: We carried out a cross-sectional study in 50 preeclamptic women with HELLP syndrome admitted to intensive care unit to determine the presence of the following criteria of hemolysis: peripheral blood schistocytes, anemia (hemoglobin ≤ 10 g/dL), lactate dehydrogenase ≥ 600 U/L, indirect bilirubin ≥ 0...
January 2016: Ginecología y Obstetricia de México
Eriseida Ndoni, Redi Hoxhallari, Astrit Bimbashi
BACKGROUND: Preeclampsia is a hypertensive multisystem disorder of pregnancy that complicates up to 10% of pregnancies worldwide and is one of the leading causes of maternal and perinatal morbidity and mortality. AIM: To evaluate maternal complications associated with severe preeclampsia. METHODS: This is a retrospective cross-sectional study conducted in the UHOG "Koço Gliozheni", in Tirana. Primary outcomes evaluated: maternal death, eclampsia, stroke, HELLP syndrome, and pulmonary edema...
March 15, 2016: Open Access Macedonian Journal of Medical Sciences
Yifru Berhan
Hypertensive disorders complicate 5%-10% of pregnancies with increasing incidence mainly due to upward trends in obesity globally. In the last century, several terminologies have been introduced to describe the spectrum of this disease. The current and widely used classification of hypertensive pregnancy disorders was introduced in 1972 and in 1982, but has not been free of controversy and confusion. Unlike other diseases, the existing terminology combines signs and symptoms, but does not describe the underlying pathology of the disease itself...
March 2016: Ethiopian Journal of Health Sciences
Mohamed El-Mahdi Boubkraoui, Hassan Aguenaou, Mustapha Mrabet, Amina Barkat
INTRODUCTION: Twin pregnancies are associated with a higher rate of perinatal morbidity and mortality than singleton pregnancies. The aim of the present study was to evaluate perinatal morbidity and mortality in twin pregnancies in a Moroccan level-3 maternity ward. METHODS: This is a comparative cross-sectional study of perinatal morbidity and mortality rates in newborn infants in twin pregnancies versus singleton pregnancies among women who gave birth at Souissi Maternity Hospital in Rabat from January 1 to February 28, 2014...
2016: Pan African Medical Journal
Ángel Augusto Pérez-Calatayud, Jesús Carlos Briones-Garduño, Mercedes Del Pilar Álvarez-Goris, Ricardo Sánchez Zamora, Angélica A Torres Aguilar, Rosa Elba Mendoza-Mórales
Atypical haemolytic uraemic syndrome is one of the main variants of thrombotic microangiopathy, and is characterized by excessive complement activation in the microvasculature. It is also characterised by the clinical triad; non-immune haemolytic anaemia, thrombocytopenia, and acute renal failure. In addition, 60% of patients have mutations in the genes encoding complement regulators (factor H, factor I, membrane cofactor proteins, and thrombomodulin), activators (factor B and C3), as well as autoantibodies against factor H...
July 2016: Cirugia y Cirujanos
S A Povzun, L Sh Gorbakova
The paper describes the morphopathological changes found at autopsy of a 42-year-old pregnant woman whose death was due to HELLP syndrome (Hemolysis, Elevated Liver enzymes, and Low Platelets) that is rarely encountered in autopsy practice and that is a type of preeclampsia. It considers the morphogenesis of these changes in the light of the pathophysiological mechanisms underlying the syndrome.
September 2015: Arkhiv Patologii
Adam Morton
This review article describes disorders that may imitate preeclampsia (PET), preeclampsia with haemolysis, elevated liver enzymes and low platelets (HELLP syndrome) and eclampsia.
January 2016: Pregnancy Hypertension
P Berlit
Neurological disorders caused by pregnancy and puerperium include the posterior reversible encephalopathy syndrome, the amniotic fluid embolism syndrome (AFES), the postpartum angiopathy due to reversible vasoconstriction syndrome, and the Sheehan syndrome. Hypertension and proteinuria are the hallmarks of preeclampsia, seizures define eclampsia. Hemolysis, elevated liver enzymes and low platelets constitute the HELLP syndrome. Vision disturbances including cortical blindness occur in the posterior reversible encephalopathy syndrome (PRES)...
February 2016: Fortschritte der Neurologie-Psychiatrie
Renato T Souza, Jose G Cecatti, Renato Passini, Ricardo P Tedesco, Giuliane J Lajos, Marcelo L Nomura, Patricia M Rehder, Tabata Z Dias, Samira M Haddad, Rodolfo C Pacagnella, Maria L Costa
BACKGROUND: About 15 million children are born under 37 weeks of gestation worldwide. Prematurity is the leading cause of neonatal deaths and short/long term morbidities, entailing consequences not only for the individual, but also their family, health agencies, facilities and all community. The provider-initiated preterm birth is currently one of the most important obstetric conditions related to preterm births, particularly in middle and high income countries, thus decreasing the need for therapeutic preterm birth is essential to reduce global prematurity...
2016: PloS One
Charles Osalumese Imarengiaye, Theodore Ojeide Isesele
INTRODUCTION: The burden of hypertensive diseases on the health care is enormous given to the high population in Sub-Saharan Africa and related disproportionate representation in global maternal mortality. MATERIALS AND METHODS: All women with hypertensive diseases of pregnancy who got admitted into the general ICU of the University of Benin Teaching Hospital between January 2006 and December 2010 were studied. Only the records of women who completed 28 weeks of gestation and were admitted during labour and delivery or puerperium to the ICU were examined...
September 2015: Nigerian Medical Journal: Journal of the Nigeria Medical Association
Tuğba Kınay, Canan Küçük, Fulya Kayıkçıoğlu, Jale Karakaya
BACKGROUND: Preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelet (HELLP) syndrome are important disorders affecting the health of both the mother and fetus. Prediction of the maternal and perinatal outcomes at early and late gestational age is important for the management of both disorders. AIMS: The purpose of the study was to investigate adverse maternal and perinatal outcomes in severe preeclampsia and HELLP syndrome cases according to gestational age...
October 2015: Balkan Medical Journal
José María Tovar-Rodríguez, Leobardo Valle-Molina, Victor Manuel Vargas-Hernández, Luis Edmundo Hernández-Vivar, Francisco Javier Hernández-Aldana, Mario Adán Moreno-Eutimio
BACKGROUND: Blood pressure (BP) has a circadian rhythm, decreases at night and increases in the morning (dipper), have been observed in patients with impaired in this profile, increased at night and lower in the morning (no dipper) have increased cardiovascular risk. Preeclampsia-eclampsia complicates about 7% of pregnancies, preeclampsia is known to reverse the normal circadian cycle of the BP. OBJECTIVE: To determine the profile dipper/non-dipper in patients with severe preeclampsia, eclampsia and HELLP syndrome patients in Intensive Care and Obstetrics Hospital Juárez of México...
August 2015: Ginecología y Obstetricia de México
Anna Jodkowska, Helena Martynowicz, Beata Kaczmarek-Wdowiak, Grzegorz Mazur
Thrombocytopenia (TP) affects 7-10% of pregnant women. It occurs 4 times more frequently in pregnancy than in the non-pregnant women population. Women with thrombocytopenia in pregnancy are a heterogeneous and poorly known group. There are several possible causes of thrombocytopenia in pregnancy. The most common are: gestational thrombocytopenia (GE) (60-75%), preeclampsia (PE) and HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome associated TP (21%), and idiopathic immune thrombocytopenia (ITP) (3-10%)...
November 12, 2015: Postȩpy Higieny i Medycyny Doświadczalnej
Eugene Belley Priso, Theophile Nana Njamen, Charlotte Nguefack Tchente, Albert Justin Kana, Tchuenkam Landry, Ulrich Flore Nyaga Tchawa, Romuald Hentchoya, Gerard Beyiha, Marie Patrice Halle, Leopold Aminde, Anastase Dzudie
INTRODUCTION: Hypertensive disorders in pregnancy (HDP) are a major cause of maternal morbidity and mortality. We aimed at determining the trends in admission, profiles and outcomes of women admitted for preeclampsia and eclampsia to an intensive care unit (ICU) in Cameroon. METHODS: A retrospective study involving 74 women admitted to the ICU of the Douala General Hospital for severe preeclampsia and eclampsia from January 2007 to December 2014. Clinical profiles and outcome data were obtained from patient records...
2015: Pan African Medical Journal
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