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https://www.readbyqxmd.com/read/28811112/exogenous-testosterone-affects-early-threat-processing-in-socially-anxious-and-healthy-women
#1
Jacobien M van Peer, Dorien Enter, Henk van Steenbergen, Philip Spinhoven, Karin Roelofs
Testosterone plays an important role in social threat processing. Recent evidence suggests that testosterone administration has socially anxiolytic effects, but it remains unknown whether this involves early vigilance or later, more sustained, processing-stages. We investigated the acute effects of testosterone administration on social threat processing in 19 female patients with Social Anxiety Disorder (SAD) and 19 healthy controls. Event-related potentials (ERPs) were recorded during an emotional Stroop task with subliminally presented faces...
August 12, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28759054/the-association-between-retinal-vein-pulsation-pressure-and-optic-disc-haemorrhages-in-glaucoma
#2
Dong An, Philip House, Christopher Barry, Andrew Turpin, Allison M McKendrick, Balwantray C Chauhan, Siobhan Manners, Stuart L Graham, Dao-Yi Yu, William H Morgan
PURPOSE: To explore the potential relationship between optic disc haemorrhage, venous pulsation pressure (VPP), ocular perfusion pressures and visual field change in glaucomatous and glaucoma suspect eyes. MATERIALS AND METHODS: This prospective observational study examined 155 open angle glaucoma or glaucoma suspect eyes from 78 patients over 5 years. Patients were followed with 3 monthly non-mydriatic disc photographs, 6 monthly standard automated perimetry and annual ophthalmodynamometry...
2017: PloS One
https://www.readbyqxmd.com/read/28743457/mental-imagery-of-face-enhances-face-sensitive-event-related-potentials-to-ambiguous-visual-stimuli
#3
Lingxi Lu, Changxin Zhang, Liang Li
Visual mental imagery forms mental representations of visual objects when correspondent stimuli are absent and shares some characters with visual perception. Both the vertex-positive-potential (VPP) and N170 components of event-related potentials (ERPs) to visual stimuli have a remarkable preference to faces. This study investigated whether visual mental imagery modulates the face-sensitive VPP and/or N170 components. The results showed that with significantly larger amplitudes under the face-imagery condition than the house-imagery condition, the VPP and P2 responses, but not the N170 component, were elicited by phase-randomized ambiguous stimuli...
July 22, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28680038/a-high-speed-electro-optic-triple-microring-resonator-modulator
#4
Jianxun Hong, Feng Qiu, Xiaoyang Cheng, Andrew M Spring, Shiyoshi Yokoyama
The coupling intensity modulator based on a triple-microring structure was proposed and numerically investigated for a high speed and a low bit error ratio (BER) operation. The modulator consists of a dual-microring optical cavity and a gate-microring energy feedback path. The optical cavity ensures a high energy storing efficiency, and the feedback path enables modulation with little intracavity energy decay. The bandwidth of 103 GHz and modulation depth of 6.2 dB at 2.0 Vpp were theoretically verified by the analysis of the sinusoidal modulation performance...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28667950/a-novel-large-thrust-weight-ratio-v-shaped-linear-ultrasonic-motor-with-a-flexible-joint
#5
Xiaoniu Li, Zhiyuan Yao, Mojian Yang
A novel large thrust-weight ratio V-shaped linear ultrasonic motor with a flexible joint is proposed in this paper. The motor is comprised of a V-shaped transducer, a slider, a clamp, and a base. The V-shaped transducer consists of two piezoelectric beams connected through a flexible joint to form an appropriate coupling angle. The V-shaped motor is operated in the coupled longitudinal-bending mode. Longitudinal and bending movements are transferred by the flexible joint between the two beams. Compared with the coupled longitudinal-bending mode of the single piezoelectric beam or the symmetrical and asymmetrical modes of the previous V-shaped transducer, the coupled longitudinal-bending mode of the V-shaped transducer with a flexible joint provides higher vibration efficiency and more convenient mode conformance adjustment...
June 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28594117/serum-anti-phenolic-glycolipid-1-iga-correlates-to-igm-isotype-in-leprosy-patients-a-possible-candidate-for-seroepidemiological-surveys
#6
Alexandre C de Macedo, Juliana A Guimarães, Raphael O Rodrigues, Thiago D V Araújo, Clodis M Tavares, Paula B Cabral, Maria Isabel de Moraes-Pinto, Aparecida T Nagao-Dias
OBJECTIVE: The aim of this study was to compare serum anti-phenolic glycolipid-1 IgA, IgG, and IgM levels in leprosy patients and controls. METHOD: Analysis of anti-PGL-1 IgA, IgG, or IgM in serum samples from multibacillary (MB, n=32) and paucibacillary (PB, n=22) leprosy patients, and in non-endemic controls (n=17), using an indirect enzyme-linked immunosorbent assay. RESULTS: A strong correlation between serum IgM and IgA isotypes was found (r=...
June 8, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28553963/frequency-dependent-stability-of-cnt-joule-heaters-in-ionizable-media-and-desalination-processes
#7
Alexander V Dudchenko, Chuxiao Chen, Alexis Cardenas, Julianne Rolf, David Jassby
Water shortages and brine waste management are increasing challenges for coastal and inland regions, with high-salinity brines presenting a particularly challenging problem. These high-salinity waters require the use of thermally driven treatment processes, such as membrane distillation, which suffer from high complexity and cost. Here, we demonstrate how controlling the frequency of an applied alternating current at high potentials (20 Vpp) to a porous thin-film carbon nanotube (CNT)/polymer composite Joule heating element can prevent CNT degradation in ionizable environments such as high-salinity brines...
July 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28467769/fear-of-vaginal-penetration-in-the-absence-of-pain-as-a-separate-category-of-female-sexual-dysfunction-a-conceptual-overview
#8
David Rabinowitz, Lior Lowenstein, Ilan Gruenwald
Functional sexual pain disorders in women are a particular challenge to the gynecologist, inasmuch as phobic avoidance and guarding on the part of the patient lead to difficulties in the gynecological examination and diagnosis. In some such cases examination may even be impossible. Vaginismus is the commonly diagnosed etiology of such cases. This article offers an overview of vaginismus and approaches to its treatment but also examines a subset of penetration-avoidant patients who do not appear to have a pain component...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28432530/an-integrated-microsystem-with-dielectrophoresis-enrichment-and-impedance-detection-for-detection-of-escherichia-coli
#9
Renjie Wang, Yi Xu, Haitao Liu, Jinlan Peng, Joseph Irudayaraj, Feiyun Cui
An integrated microsystem device with matched interdigitated microelectrode chip was fabricated for enrichment and detection of Escherichia coli O157:H7. The microsystem has integrated with positive dielectrophoresis (pDEP) enrichment and in situ impedance detection, whose total volume is only 3.0 × 10(-3) m(3), and could provide impedance testing voltages of 0 ~ 10 V, detection frequencies of 1 KHz ~ 1 MHz, DEP excitation signals with amplitude of 0 ~ 10 Vpp and frequencies of 1KHz ~ 1 MHz, which fully meets the demands of pDEP enrichment and impedance detection for bacteria...
June 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28401227/in-situ-mrna-isolation-from-a-microfluidic-single-cell-array-using-an-external-afm-nanoprobe
#10
Xuan Li, Yinglei Tao, Do-Hyun Lee, Hemantha K Wickramasinghe, Abraham P Lee
We present an in situ mRNA extraction platform to quantify marker-genes' expression levels of single target cells within high-density microfluidic trapping arrays. This platform enables single-cell transcriptomic analysis to reveal in-depth information of cellular mechanisms and population heterogeneity. Although microfluidic technology enables the automation of single-cell sorting, trapping and identification, most developed microfluidic devices are closed off and prevent single-cell access by external analytical equipment...
May 2, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28337179/characterization-of-a-novel-nicotine-degradation-gene-cluster-ndp-in-sphingomonas-melonis-ty-and-its-evolutionary-analysis
#11
Haixia Wang, Xiao-Yang Zhi, Jiguo Qiu, Longxiang Shi, Zhenmei Lu
Sphingomonas melonis TY utilizes nicotine as a sole source of carbon, nitrogen, and energy through a variant of the pyridine and pyrrolidine pathways (VPP). A 31-kb novel nicotine-degrading gene cluster, ndp, in strain TY exhibited a different genetic organization with the vpp cluster in strains Ochrobactrum rhizosphaerae SJY1 and Agrobacterium tumefaciens S33. Genes in vpp were separated by a 20-kb interval sequence, while genes in ndp were localized together. Half of the homolog genes were in different locus in ndp and vpp...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28333640/integrated-hifu-drive-system-on-a-chip-for-cmut-based-catheter-ablation-system
#12
Omid Farhanieh, Ali Sahafi, Rupak Bardhan Roy, Arif Sanli Ergun, Ayhan Bozkurt
Conventional High Intensity Focused Ultrasound (HIFU) is a therapeutic modality which is extracorporeally administered. In applications where a relatively small HIFU lesion is required, an intravascular HIFU probe can be deployed to the ablation site. In this paper, we demonstrate the design and implementation a fully integrated HIFU drive system on a chip to be placed on a 6 Fr catheter probe. An 8-element capacitive micromachined ultrasound transducer (CMUT) ring array of 2 mm diameter has been used as the ultrasound source...
June 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28273880/5-v-compatible-two-axis-pzt-driven-mems-scanning-mirror-with-mechanical-leverage-structure-for-miniature-lidar-application
#13
Liangchen Ye, Gaofei Zhang, Zheng You
The MEMS (Micro-Electronical Mechanical System) scanning mirror is an optical MEMS device that can scan laser beams across one or two dimensions. MEMS scanning mirrors can be applied in a variety of applications, such as laser display, bio-medical imaging and Light Detection and Ranging (LiDAR). These commercial applications have recently created a great demand for low-driving-voltage and low-power MEMS mirrors. However, no reported two-axis MEMS scanning mirror is available for usage in a universal supplying voltage such as 5 V...
March 5, 2017: Sensors
https://www.readbyqxmd.com/read/28269539/a-numerical-and-experimental-study-of-acoustic-micromixing-in-3d-microchannels-for-lab-on-a-chip-devices
#14
Susana O Catarino, Vania C Pinto, Paulo J Sousa, Rui Lima, Joao M Miranda, Graca Minas
This paper reports a numerical and experimental study of acoustic streaming and micromixing in polydimethylsiloxane microchannels. The mixing between two fluids flowing in microchannels was evaluated through the following conditions: (1) using a 28 μm thick β-poly(vinylidene fluoride) (β-PVDF) as a piezoelectric transducer actuated with a 24 Vpp and 40 MHz sinusoidal voltage; (2) using different flow rates. The results suggest that the mixing length increases as the flow rate increases and that the acoustic streaming phenomenon leads to a reduction on the mixing length...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268180/emat-phased-array-a-feasibility-study-of-surface-crack-detection
#15
J Isla, F Cegla
Electromagnetic-acoustic transducers (EMATs) consist of a magnet and a coil. They are advantageous in some non-destructive evaluation (NDE) applications because no direct contact with the specimen is needed to send and receive ultrasonic waves. However, EMATs commonly require excitation peak powers greater than 1kW and therefore the driving electronics and the EMAT coils have to be bulky. This has hindered the development of EMAT phased arrays with characteristics similar to those of conventional piezoelectric phased arrays...
February 14, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28227794/a-numerical-and-experimental-study-of-acoustic-micromixing-in-3d-microchannels-for-lab-on-a-chip-devices
#16
Susana O Catarino, Vania C Pinto, Paulo J Sousa, Rui Lima, Joao M Miranda, Graca Minas, Susana O Catarino, Vania C Pinto, Paulo J Sousa, Rui Lima, Joao M Miranda, Graca Minas, Joao M Miranda, Paulo J Sousa, Susana O Catarino, Rui Lima, Vania C Pinto, Graca Minas
This paper reports a numerical and experimental study of acoustic streaming and micromixing in polydimethylsiloxane microchannels. The mixing between two fluids flowing in microchannels was evaluated through the following conditions: (1) using a 28 μm thick β-poly(vinylidene fluoride) (β-PVDF) as a piezoelectric transducer actuated with a 24 Vpp and 40 MHz sinusoidal voltage; (2) using different flow rates. The results suggest that the mixing length increases as the flow rate increases and that the acoustic streaming phenomenon leads to a reduction on the mixing length...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28113241/m3ba-a-mobile-modular-multimodal-biosignal-acquisition-architecture-for-miniaturized-eeg-nirs-based-hybrid-bci-and-monitoring
#17
Alexander von Luhmann, Heidrun Wabnitz, Tilmann Sander, Klaus-Robert Muller
OBJECTIVE: For the further development of the fields of telemedicine, neurotechnology and Brain-Computer Interfaces (BCI), advances in hybrid multimodal signal acquisition and processing technology are invaluable. Currently, there are no commonly available hybrid devices combining bio-electrical and bio-optical neurophysiological measurements (here Electroencephalography (EEG) and functional Near Infrared Spectroscopy (fNIRS)). Our objective was the design of such an instrument, and that in a miniaturized, customizable and wireless form...
September 9, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28109158/using-the-volta-phase-plate-with-defocus-for-cryo-em-single-particle-analysis
#18
Radostin Danev, Dimitry Tegunov, Wolfgang Baumeister
Previously, we reported an in-focus data acquisition method for cryo-EM single-particle analysis with the Volta phase plate (Danev and Baumeister, 2016). Here, we extend the technique to include a small amount of defocus which enables contrast transfer function measurement and correction. This hybrid approach simplifies the experiment and increases the data acquisition speed. It also removes the resolution limit inherent to the in-focus method thus allowing 3D reconstructions with resolutions better than 3 Å...
January 21, 2017: ELife
https://www.readbyqxmd.com/read/28057515/evidence-for-erp-biomarkers-of-eating-disorder-symptoms-in-women
#19
Katie Groves, Steffan Kennett, Helge Gillmeister
Growing evidence suggests that the brain processes bodies distinctively from other stimuli, but little research has addressed whether visual body perception is modulated by the observer's thoughts and feelings about their own body. The present study thus investigated the relationship between body image and electrophysiological signatures of body perception, with the aim of identifying potential biomarkers of body image disturbances. Occipito-parietal (P1 and N1) and fronto-central (VPP) processing of body and non-body stimuli were assessed in 29 weight-restored eating disordered (ED) women and compared to 27 healthy controls...
January 3, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28052986/can-voluntary-pooled-procurement-reduce-the-price-of-antiretroviral-drugs-a-case-study-of-efavirenz
#20
Sung Wook Kim, Jolene Skordis-Worrall
Purpose: : A number of strategies have aimed to assist countries in procuring antiretroviral therapy (ARV) at lower prices. In 2009, as the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) commenced a voluntary pooled procurement scheme, however, the impact of the scheme on ARV prices remains uncertain. This study aims to estimate the effect of VPP on drug prices using Efavirenz as a case study. Methods: This analysis uses WHO Global price report mechanism (GPRM) data from 2004 to 2013...
May 1, 2017: Health Policy and Planning
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