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https://www.readbyqxmd.com/read/28653609/lncrna-meg3-inhibits-cell-proliferation-and-metastasis-in-chronic-myeloid-leukemia-via-targeting-mir-184
#1
Jingdong Li, Youmei Zi, Wanling Wang, Yan Li
Maternally expressed gene 3 (MEG3), a long non-coding RNA, has been reported to be associated with the pathogenesis ofmultiple malignancies. However, little is known regarding the role of MEG3 in leukemia. In this study, we found that the expression of MEG3 was decreased in leukemia patients and cell lines, and has potential to be considered as a biomarker for leukemia. In addition, overexpression of MEG3 inhibited cell proliferation and invasion in vitro and in vivo. Moreover, a potential bonding site between miR-184 and MEG3 was predicted, and low expression of miR-184 was found in leukemia patients and cell lines...
June 22, 2017: Oncology Research
https://www.readbyqxmd.com/read/28631931/induction-of-lactation-in-the-biological-mother-after-gestational-surrogacy-of-twins-a-novel-approach-and-review-of-literature
#2
Roya Farhadi, Roy K Philip
One of the important challenges in surrogate pregnancies is the early bonding of genetic mother with her infant and the establishment of breastfeeding. A combination of pharmacological and nonpharmacological methods is often used for the induction of lactation. Reports of induced lactation in surrogacy are limited and scattered. In this report, we present a case of induced lactation and initiation of breastfeeding in preterm twins by the genetic mother, through her novel approach after a gestational surrogate pregnancy...
June 20, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28631023/the-influence-of-perceived-parenting-styles-on-socio-emotional-development-from-pre-puberty-into-puberty
#3
Min Yee Ong, Janna Eilander, Seang Mei Saw, Yuhuan Xie, Michael J Meaney, Birit F P Broekman
The relative impact of parenting on socio-emotional development of children has rarely been examined in a longitudinal context. This study examined the association between perceived parenting styles and socio-emotional functioning from childhood to adolescence. We hypothesized that optimal parenting associated with improvement in socio-emotional functioning from childhood into early adulthood, especially for those with more behavioral problems in childhood. Children between ages 7 and 9 years were recruited for the Singapore Cohort Study of Risk Factors for Myopia (SCORM)...
June 19, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28625307/postcesarean-delivery-analgesia
#4
REVIEW
Brendan Carvalho, Alexander J Butwick
Effective pain management should be a key priority in women undergoing cesarean delivery. Suboptimal perioperative pain management is associated with chronic pain, greater opioid use, delayed functional recovery, impaired maternal-fetal bonding, and increased postpartum depression. Severe acute postoperative pain is also strongly associated with persistent pain after cesarean delivery. Multimodal analgesia is the core principle for cesarean delivery pain management. The use of neuraxial morphine and opioid-sparing adjuncts such as scheduled nonsteroidal anti-inflammatory medications and acetaminophen is recommended for all women undergoing cesarean delivery with neuraxial anesthesia unless contraindicated...
March 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/28621206/baseline-population-health-conditions-ahead-of-a-health-system-strengthening-program-in-rural-madagascar
#5
Ann C Miller, Ranto H Ramananjato, Andres Garchitorena, Victor R Rabeza, Djordje Gikic, Amber Cripps, Laura Cordier, Hery-Tiana Rahaniraka Razanadrakato, Marius Randriamanambintsoa, Lara Hall, Megan Murray, Felicite Safara Razanavololo, Michael L Rich, Matthew H Bonds
BACKGROUND: A model health district was initiated through a program of health system strengthening (HSS) in Ifanadiana District of southeastern Madagascar in 2014. We report population health indicators prior to initiation of the program. METHODS: A representative household survey based on the Demographic Health Survey was conducted using a two-stage cluster sampling design in two strata - the initial program catchment area and the future catchment area. Chi-squared and t-tests were used to compare data by stratum, using appropriate sampling weights...
2017: Global Health Action
https://www.readbyqxmd.com/read/28573830/the-psychophysiological-effects-of-oxytocin-on-parent-child-interactions-a-literature-review-oxytocin-and-parent-child-interactions
#6
REVIEW
Monika Szymanska, Marie Schneider, Carmela Chateau-Smith, Sylvie Nezelof, Lauriane Vulliez-Coady
Oxytocin (OT), often called the "hormone of love" or "hormone of attachment", plays a fundamental role in the establishment and quality of parent-infant bonding. However, emerging evidence indicates that OT can also produce antisocial behavior. To clarify these effects, we review studies examining the role of endogenous and exogenous OT on several determinants of attachment: parental sensitivity, and bonding or synchrony in parent-child dyads. Contextual and individual factors moderating the effect of intranasal OT (INOT) and its peripheral levels are also reviewed...
June 2, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28572718/longitudinal-associations-between-parental-bonding-parenting-stress-and-executive-functioning-in-toddlerhood
#7
Evi S A de Cock, Jens Henrichs, Theo A Klimstra, A Janneke B M Maas, Charlotte M J M Vreeswijk, Wim H J Meeus, Hedwig J A van Bakel
Early executive functioning is an important predictor for future development of children's cognitive skills and behavioral outcomes. Parenting behavior has proven to be a key environmental determinant of child executive functioning. However, the association of parental affect and cognitions directed to the child with child executive functioning has been understudied. Therefore, in the present study we examine the associations between parental bonding (i.e., the affective tie from parent to child), parenting stress, and child executive functioning...
2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/28556440/relationship-between-maternal-depression-and-bonding-failure-a-prospective-cohort-study-of-pregnant-women
#8
Masako Ohara, Takashi Okada, Chika Kubota, Yukako Nakamura, Tomoko Shiino, Branko Aleksic, Mako Morikawa, Aya Yamauchi, Yota Uno, Satomi Murase, Setsuko Goto, Atsuko Kanai, Tomoko Masuda, Masahiko Ando, Norio Ozaki
AIM: Although the association between maternal depression and bonding failure during pregnancy and after delivery has been investigated, the causal relationships remain unclear. METHODS: A total of 751 women (mean [SD] age 32.1 [4.4] years) completed the Mother-Infant Bonding Questionnaire and the Edinburgh Postnatal Depression Scale in early pregnancy before week 25 (T1), in late pregnancy around week 36 (T2), and 5 days after delivery (T3). We created a structural regression model to clarify the relationships between depressive mood and bonding failure during pregnancy and 5 days after delivery...
May 29, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28538937/-mother-child-relationship-and-associated-factors-hierarchical-analysis-of-the-population-base-in-a-brazilian-state-capital-brisa-study
#9
Milady Cutrim Vieira Cavalcante, Fernando Lamy, Ana Karina Teixeira da Cunha França, Zeni Carvalho Lamy
Several factors can interfere in the mother-child relationship. Studies about different maternal characteristics and this relationship are scarce; they mainly evaluate women with psychopathology and use simultaneous regression models with adjustment for multiple confounders. This study aimed to assess factors associated with losses in the mother-child relationship through a cohort of 3,215 mothers of children between 15 and 36 months of age. Losses in the mother-child relationship, assessed by the Postpartum Bonding Questionnaire, was the outcome variable and the explanatory variables were demographic, socioeconomic, reproductive health and mental health of mothers as well as the conditions of the birth of children...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28525984/study-protocol-evaluation-of-the-probiotic-lactobacillus-fermentum-cect5716-for-the-prevention-of-mastitis-in-breastfeeding-women-a-randomised-controlled-trial
#10
Diana M Bond, Jonathan M Morris, Natasha Nassar
BACKGROUND: Mastitis and accompanying pain have been associated with the cessation of breastfeeding. Mastitis is an inflammatory condition of the breast and may be a result of decreased immunity and a lowered resistance to infection. Mastitis affects up to one in five breastfeeding women with most episodes occurring in the first 6-8 weeks postpartum. Antibiotics are often used in the treatment of mastitis, but have not been popular or proven effective as a preventative agent. The WHO has highlighted significant concerns relating to adverse harms of antibiotic use with the production of antibiotic-resistant strains of disease organisms...
May 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28525980/the-distribution-of-mitochondrial-dna-haplogroup-h-in-southern-iberia-indicates-ancient-human-genetic-exchanges-along-the-western-edge-of-the-mediterranean
#11
Candela L Hernández, Jean M Dugoujon, Andrea Novelletto, Juan N Rodríguez, Pedro Cuesta, Rosario Calderón
BACKGROUND: The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the westernmost Mediterranean coasts, which were settled by individuals from two continents separated by a relatively narrow body of water, show the highest frequencies of mitochondrial haplogroup H. These characteristics permit the analysis of ancient migrations between both shores, which may have occurred via primitive sea crafts and early seafaring...
May 19, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28525876/discrete-category-of-mother-to-infant-bonding-disorder-and-its-identification-by-the-mother-to-infant-bonding-scale-a-study-in-japanese-mothers-of-a-1-month-old
#12
Asami Matsunaga, Fumie Takauma, Katsuhiko Tada, Toshinori Kitamura
BACKGROUND: Difficulty of maternal bonding towards a baby is widely recognised. It is unclear whether this phenomenon is dimensional or categorical. If categorical, an optimal cut-off score of a screening instrument is needed in clinical settings. AIMS: In this study, we investigated whether maternal bonding is dimensional or categorical phenomenon and try to set optimal cut-off score of screening instruments. METHODS: Self-report questionnaire studies were conducted in a general hospital and four antenatal clinics...
May 16, 2017: Early Human Development
https://www.readbyqxmd.com/read/28501400/the-genetics-of-antibody-response-to-paratuberculosis-in-dairy-cattle
#13
T Pritchard, R Mrode, M Coffey, K Bond, E Wall
Genetic parameters were estimated for antibody response to paratuberculosis (Mycobacterium avium ssp. paratuberculosis) using milk ELISA test results, collected and analyzed by National Milk Records, from Holstein Friesian cows on UK dairy farms in their first 3 lactations. Milk ELISA test results were obtained from 2007 to 2012 and combined with milk recording data and pedigree information. The reduced data set edited for the purposes of genetic parameter estimation consisted of 148,054 milk ELISA records from 64,645 lactations in 40,142 cows of 908 sires, recorded in 641 herds...
July 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28470155/-the-relationships-among-perceived-parental-bonding-illness-perception-and-anxiety-in-adult-patients-with-congenital-heart-diseases
#14
Nayeon Shin, Youha Jang, Younhee Kang
PURPOSE: The purposes of this study were to identify the relationships among perceived parental bonding, illness perception, and anxiety and to determine the influences of perceived parental bonding and illness perception on anxiety in adult patients with congenital heart diseases. METHODS: In this study a descriptive correlational design with survey method was utilized. The participants were 143 adult patients with congenital heart disease being cared for in the cardiology out-patient clinic of A medical center...
April 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28464352/maternal-experience-raising-girls-with-autism-spectrum-disorder-a-qualitative-study
#15
N Navot, A G Jorgenson, S J Webb
BACKGROUND: A growing line of research has sought to characterize the different presentations of autism spectrum disorder (ASD) among boys and girls. Much less is known about maternal experience and mother-child relationship in children with ASD based on child gender. The present qualitative study aimed to investigate the mother-daughter relationship from the perspective of mothers who are raising girls with ASD with normal intelligence and functional verbal communication. METHODS: Eleven in-depth interviews were conducted with mothers of girls with ASD, ages 10-19 years...
May 2, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28458552/perceived-parental-affectionless-control-is-associated-with-high-neuroticism
#16
Nana Takahashi, Akihito Suzuki, Yoshihiko Matsumoto, Toshinori Shirata, Koichi Otani
OBJECTIVE: Depressed patients are prone to perceive that they were exposed to affectionless control by parents. Meanwhile, high neuroticism is a well-established risk factor for developing depression. Therefore, this study examined whether perceived parental affectionless control is associated with high neuroticism. METHODS: The subjects were 664 healthy Japanese volunteers. Perceived parental care and protection were assessed by the Parental Bonding Instrument...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28439234/salivary-oxytocin-concentration-associates-with-the-subjective-feeling-of-body-ownership-during-the-rubber-hand-illusion
#17
Masakazu Ide, Makoto Wada
Oxytocin is a hormone of the posterior pituitary that promotes lactation, maternal bonding, and birth. Recent studies have shown that oxytocin may modulate social recognition in both sexes, and thus it may be related to empathy. Brain regions that are associated with social recognition and empathy (e.g., the insular cortex) are activated in the rubber hand illusion (RHI), which involves illusory ownership of a rubber hand caused by brush strokes applied synchronously to both a rubber hand and one of the participant's hand, which is hidden from view...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28391110/the-influence-of-parental-care-and-overprotection-neuroticism-and-adult-stressful-life-events-on-depressive-symptoms-in-the-general-adult-population
#18
Yasuyuki Ono, Yoshikazu Takaesu, Yukiei Nakai, Masahiko Ichiki, Jiro Masuya, Ichiro Kusumi, Takeshi Inoue
BACKGROUND: The quality of parenting, neuroticism, and adult stressful life events are reportedly associated with depressive symptoms. However, previous studies have not examined the complex interaction between these three factors. In this study, we hypothesized that the quality of parenting (care and overprotection) acts on depressive symptoms through 'neuroticism' and the appraisal of adult stressful life events, and this hypothesis was verified by structural equation modeling. METHODS: Four hundred one participants from the general adult population were studied using the following self-administered questionnaire surveys: Patient Health Questionnaire-9 (PHQ-9), Parental Bonding Instrument (PBI), neuroticism subscale of the short version of the Eysenck Personality Questionnaire-revised (EPQ-R), and Life Experiences Survey (LES)...
August 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28293197/serotonin-transporter-gene-polymorphisms-and-early-parent-infant-interactions-are-related-to-adult-male-heart-rate-response-to-female-crying
#19
Anna Truzzi, Marc H Bornstein, Vincenzo P Senese, Kazuyuki Shinohara, Peipei Setoh, Gianluca Esposito
Adults' adaptive interactions with intimate partners enhance well-being. Here we hypothesized that adult males' physiological responses to opposite-sex conspecifics' distress result from an interaction between an environmental factor (early social interaction with caregivers) and a genetic factor (a polymorphism within the promoter region of the serotonin transporter gene, 5-HTTLPR). We assessed heart rate changes in 42 non-married male adults to distress vocalizations (female, infant, and bonobo cries). Males' early interaction with parents was assessed using the Parental Bonding Instrument...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28286539/potential-exposure-to-endocrine-disrupting-chemicals-and-selected-adverse-pregnancy-outcomes-a-follow-up-study-of-pregnant-women-referred-for-occupational-counselling
#20
Jessica Bengtsson, Pernille Søgaard Thygesen, Linda Kaerlev, Lisbeth E Knudsen, Jens Peter Bonde
BACKGROUND: Experimental evidence indicates that fetal exposure to xenobiotics with the potential to interfere with the endogenous steroid hormone regulation of fetal development may reduce birth weight. However, epidemiological studies are limited. The aim of the study was to investigate whether potential occupational exposure to endocrine disrupting chemicals (EDC) of the mother during pregnancy is associated with preterm birth and low birth weight. METHODS: Pregnant women referred to an Occupational Health Clinic (OHC) in two Danish regions (Copenhagen or Aarhus) between 1984 and 2010, suspected of being exposed to occupational reproductive hazards were included in the study...
2017: Journal of Occupational Medicine and Toxicology
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