keyword
https://read.qxmd.com/read/38532432/implementing-and-evaluating-group-interpersonal-therapy-for-postnatal-depression-in-lebanon-and-kenya-individually-randomised-superiority-trial
#1
JOURNAL ARTICLE
Peter Fonagy, Rabih El Chammay, Carol Ngunu, Manasi Kumar, Lena Verdeli, Elizabeth Allison, Ghida Anani, Pasco Fearon, Fouad Fouad, Zoe Hoare, Lucina Koyio, Henrietta Moore, Andrew Nyandigisi, Stephen Pilling, Hannah Sender, Jolene Skordis, Rachel Evans, Gerard Joseph Abou Jaoude, Beatrice Madeghe, Sandra Pardi Arsen Maradian, Ciara O'Donnell, Elizabeth Simes, Alexandra Truscott, Grace Nduku Wambua, Obadia Yator
BACKGROUND: Depression ranks as the foremost mental health concern among childbearing women. Within low- and middle-income countries (LMICs), between 20 and 25% of women encounter depression during pregnancy or soon after delivery. This condition impacts not only the mothers but also their offspring. Offspring of women suffering from postnatal depression (PND) exhibit suboptimal cognitive development and increased emotional and behavioural issues throughout their growth. This scenario becomes more pronounced in LMICs, where numerous adversities further jeopardise children's developmental progress...
March 26, 2024: Trials
https://read.qxmd.com/read/38528557/factors-associated-with-antenatal-depression-among-women-attending-antenatal-care-at-mubende-regional-referral-hospital-a-cross-sectional-study
#2
JOURNAL ARTICLE
Musa Kasujja, Samuel Omara, Nasifu Senkungu, Shamim Ndibuuza, Joseph Kirabira, Usman Ibe, Lyse Barankunda
INTRODUCTION: This study aimed to investigate the prevalence, severity, and factors associated with antenatal depression among women receiving antenatal care at Mubende Regional Referral Hospital (MRRH) in Uganda. Antenatal depression is a critical concern for maternal and child well-being, as it is associated with adverse outcomes such as preterm birth, abortion, low birth weight, and impaired maternal-infant bonding. Despite several international guidelines recommending routine screening for antenatal depression, local Ugandan guidelines often overlook this essential aspect of maternal care...
March 25, 2024: BMC Women's Health
https://read.qxmd.com/read/38521763/functional-screening-in-human-hspcs-identifies-optimized-protein-based-enhancers-of-homology-directed-repair
#3
JOURNAL ARTICLE
Juan A Perez-Bermejo, Oghene Efagene, William M Matern, Jeffrey K Holden, Shaheen Kabir, Glen M Chew, Gaia Andreoletti, Eniola Catton, Craig L Ennis, Angelica Garcia, Trevor L Gerstenberg, Kaisle A Hill, Aayami Jain, Kristina Krassovsky, Cassandra D Lalisan, Daniel Lord, B Joy Quejarro, Jade Sales-Lee, Meet Shah, Brian J Silva, Jason Skowronski, Yuri G Strukov, Joshua Thomas, Michael Veraz, Twaritha Vijay, Kirby A Wallace, Yue Yuan, Jane L Grogan, Beeke Wienert, Premanjali Lahiri, Sebastian Treusch, Daniel P Dever, Vanessa B Soros, James R Partridge, Kristen L Seim
Homology Directed Repair (HDR) enables precise genome editing, but the implementation of HDR-based therapies is hindered by limited efficiency in comparison to methods that exploit alternative DNA repair routes, such as Non-Homologous End Joining (NHEJ). In this study, we develop a functional, pooled screening platform to identify protein-based reagents that improve HDR in human hematopoietic stem and progenitor cells (HSPCs). We leverage this screening platform to explore sequence diversity at the binding interface of the NHEJ inhibitor i53 and its target, 53BP1, identifying optimized variants that enable new intermolecular bonds and robustly increase HDR...
March 23, 2024: Nature Communications
https://read.qxmd.com/read/38518689/the-turkish-version-of-the-postpartum-bonding-questionnaire-pbq-examination-of-the-validity-and-reliability-and-scale-structure
#4
JOURNAL ARTICLE
Melike Dişsiz, Fadime Bayrı Bingöl, Meltem Demirgöz Bal, Zeynep Dilşah Karaçam Yılmaz, Ayşe Karakoç, Zümrüt Bilgin
PURPOSE: The aim of this study is to investigate the validity and reliability of the Turkish version of the Postpartum Bonding Questionnaire (PBQ). DESIGN AND METHODS: This methodological study was conducted with 250 women who presented to three family health centers in Istanbul/Turkey between April and June 2022 and met the sampling criteria. Validity analysis was performed using the content validity index, exploratory factor analysis, and confirmatory factor analysis...
March 21, 2024: Journal of Pediatric Nursing
https://read.qxmd.com/read/38512137/muslim-women-s-experiences-with-infertility-a-literature-review
#5
JOURNAL ARTICLE
Samia Jamal Abdelnabi
OBJECTIVE: Infertility affects one in six women worldwide, playing a large role on an individual's psychosocial wellbeing and quality of life. The purpose of this review was to examine the experiences of Muslim women with infertility. METHODS: A Prisma-guided literature review was conducted in Scopus, CINAHL, PubMed, Embase, PsychInfo, and Google Scholar. Sample inclusion criteria included research that examined the psychosocial consequences of infertility in women, used a qualitative design, were from a Muslim majority country or specified participants were Muslim, and were published in the English-language since 2013...
March 21, 2024: MCN. the American Journal of Maternal Child Nursing
https://read.qxmd.com/read/38508459/maternal-prenatal-depressive-symptoms-and-child-brain-responses-to-affective-touch-at-two-years-of-age
#6
JOURNAL ARTICLE
Shashank Shekhar, Pauliina Hirvi, Ambika Maria, Kalle Kotilahti, Jetro J Tuulari, Linnea Karlsson, Hasse Karlsson, Ilkka Nissilä
BACKGROUND: Touch is an essential form of mother-child interaction, instigating better social bonding and emotional stability. METHODS: We used diffuse optical tomography to explore the relationship between total haemoglobin (HbT) responses to affective touch in the child's brain at two years of age and maternal self-reported prenatal depressive symptoms (EPDS). Affective touch was implemented via slow brushing of the child's right forearm at 3 cm/s and non-affective touch via fast brushing at 30 cm/s...
March 18, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38495018/care-of-an-infant-born-with-a-cleft-palate-a-case-study
#7
JOURNAL ARTICLE
Bethany Eridani-Ball, Mandy Jane Brimble
Orofacial clefts are the most common facial congenital abnormalities in humans. Their management is complex due to a range of immediate and ongoing challenges. These include breathing, feeding, speech, hearing and dental issues. This article uses a case study approach to outline these challenges for a patient who was born with a cleft palate. The case is followed by a discussion of contemporary evidence-based care. The article focuses on family-centred care and multidisciplinary teamwork, and the author also details the central role of the children's nurse...
March 18, 2024: Nursing Children and Young People
https://read.qxmd.com/read/38489526/abm-position-statement-paid-maternity-leave-importance-to-society-breastfeeding-and-sustainable-development
#8
JOURNAL ARTICLE
Maria Enrica Bettinelli, Julie Patricia Smith, Rukhsana Haider, Zaharah Sulaiman, Elizabeth Stehel, Michal Young, Melissa Bartick
Background: Paid maternity leave benefits all of society, reducing infant mortality and providing economic gains. It is endorsed by international treaties. Paid maternity leave is important for breastfeeding, bonding, and recovery from childbirth. Not all mothers have access to adequate paid maternity leave. Key Information: Paid leave helps meet several of the 17 United Nations' Sustainable Development Goals (2, 3, 4, 5, 8, and 10), including fostering economic growth. A family's expenses will rise with the arrival of an infant...
March 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38488298/maternal-use-of-nitrosatable-drugs-during-pregnancy-and-adult-male-reproductive-health-a-population-based-cohort-study
#9
JOURNAL ARTICLE
Pernille Jul Clemmensen, Nis Brix, Jörg Schullehner, Gunnar Toft, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Anne Ahrendt Bjerregaard, Thorhallur Ingi Halldorsson, Sjurdur Frodi Olsen, Birgitte Hansen, Leslie Thomas Stayner, Torben Sigsgaard, Henrik Kolstad, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau-Hansen
BACKGROUND: Prenatal exposures to xenobiotics during the masculinization programming window are suggested to impact male fecundity later in life. Frequently used nitrosatable drugs, such as penicillins and beta2-agonists, contain amines or amides that may form teratogenic compounds in reaction with nitrite. OBJECTIVES: We explored whether maternal nitrosatable drug use during gestation was associated with biomarkers of male fecundity in adulthood; moreover, the potential modifiable effect of nitrate and vitamin intake was investigated...
March 15, 2024: Andrology
https://read.qxmd.com/read/38473138/effects-of-supplementation-with-oregano-essential-oil-during-late-gestation-and-lactation-on-serum-metabolites-antioxidant-capacity-and-fecal-microbiota-of-sows
#10
JOURNAL ARTICLE
Yuanyi Zhang, Yuhang Deng, Yubin Hao, Jianmin Fang, Jie Feng
A total of 20 healthy white × landrace sows were evenly and randomly divided into two groups, and fed basal diets unsupplemented or supplemented with 500 g/t Meriden-Stim® from day 100 of gestation until day 21 of lactation. Serum and fecal samples were collected from the sows on the final day for subsequent analysis. Compared to the control group, there were no significant differences in the sows' performances; however, an increase was observed in the piglets' weight at weaning ( p = 0.08). Moreover, oregano essential oil (OEO) significantly reduced the levels of urea (UREA) ( p < 0...
February 28, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38473074/maternal-supplementation-with-ornithine-promotes-placental-angiogenesis-and-improves-intestinal-development-of-suckling-piglets
#11
JOURNAL ARTICLE
Yun Yang, Guanyu Hou, Fengjie Ji, Hanlin Zhou, Renlong Lv, Chengjun Hu
The blood vessels of the placenta are crucial for fetal growth. Here, lower vessel density and ornithine (Orn) content were observed in placentae for low-birth-weight fetuses versus normal-birth-weight fetuses at day 75 of gestation. Furthermore, the Orn content in placentae decreased from day 75 to 110 of gestation. To investigate the role of Orn in placental angiogenesis, 48 gilts (Bama pig) were allocated into four groups. The gilts in the control group were fed a basal diet (CON group), while those in the experimental groups were fed a basal diet supplemented with 0...
February 22, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38468697/maternal-periconception-food-insecurity-and-postpartum-parenting-stress-and-bonding-outcomes
#12
JOURNAL ARTICLE
Karina M Shreffler, Caitlin M Dressler, Lucia Ciciolla, Marianna S Wetherill, Julie M Croff
Food insecurity during pregnancy is associated with various adverse pregnancy outcomes for the mother and infant, but less is known about the role of periconception food insecurity and its links to maternal and child wellbeing in the postpartum period. In a sample of 115 diverse (41% white) and predominately low-income mothers, results of hierarchical regression analyses showed that periconception food insecurity was positively associated with parenting stress at 2 months postpartum. A negative association between food insecurity and maternal-infant bonding at 6 months postpartum was mediated after controlling for prenatal depression, social support, and demographic factors...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38462460/spiritual-support-to-improve-women-s-mental-health-after-miscarriage-and-stillbirth-a-qualitative-study-in-japan
#13
JOURNAL ARTICLE
Yuko Endo, Izumi Saito
PROBLEM: Miscarriage and stillbirth can severely impact maternal mental well-being. BACKGROUND: In Japan, local municipalities must prepare systems to provide mental and social-spiritual support to women after miscarriage or stillbirth. OBJECTIVE: To elucidate what spiritually supports the mental health of women who have experienced miscarriages and stillbirths. METHODS: This analysis included 25 women who had experienced miscarriage or stillbirth at least one month previously and participated in self-help group meetings at least twice...
February 8, 2024: Kobe Journal of Medical Sciences
https://read.qxmd.com/read/38445095/potentially-modifiable-risk-and-protective-factors-affecting-mental-and-emotional-wellness-in-pregnancy
#14
JOURNAL ARTICLE
Fiona Wohrer, Helen Ngo, Jared DiDomenico, Xingya Ma, Melissa H Roberts, Ludmila N Bakhireva
INTRODUCTION: Impaired mental and emotional wellness often co-occurs with prenatal substance use, and both affect infant socio-emotional, cognitive, language, motor, and adaptive behavioral outcomes. Guided by the modified biopsychosocial framework, this study examined the role of common substance exposures during pregnancy (i.e., alcohol and cannabis), socio-cultural factors (social support during pregnancy, adverse childhood experiences), and reproductive health factors on maternal mental health (MMH)...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38443924/the-role-of-a-community-health-worker-delivered-preconception-and-pregnancy-intervention-in-achieving-a-more-positive-pregnancy-experience-the-bukhali-trial-in-soweto-south-africa
#15
JOURNAL ARTICLE
Larske M Soepnel, Khuthala Mabetha, Shane A Norris, Molebogeng Motlhatlhedi, Nokuthula Nkosi, Sonja Klingberg, Stephen Lye, Catherine E Draper
BACKGROUND: A patient-centered, human-rights based approach to maternal care moves past merely reducing maternal mortality and morbidity, towards achieving a positive pregnancy experience. When evaluating an intervention, particularly in the context of the complex challenges facing maternal care in South Africa, it is therefore important to understand how intervention components are experienced by women. We aimed to qualitatively explore (i) factors influencing the pregnancy and postpartum experience amongst young women in Soweto, South Africa, and (ii) the influence of Bukhali, a preconception, pregnancy, and early childhood intervention delivered by community health workers (CHWs), on these experiences...
March 5, 2024: BMC Women's Health
https://read.qxmd.com/read/38435959/impact-of-early-bonding-during-the-maternal-sensitive-period-on-long-term-effects-a-systematic-review
#16
REVIEW
Suresh Babu Mendu, Aruna Rekha Neela, Saritha Tammali, Rakesh Kotha
This research project examines the long-term effects of maternal-neonatal bonding during a mother's "sensitive period." The review explores how early contact between a mother and her newborn can affect their psychosocial and emotional well-being in the future. Within an hour after birth, oxytocin levels increase for mothers, while catecholamine surges enhance neonates' memory retention to encourage immediate skin-to-skin contact (SSC), which promotes breastfeeding with benefits, such as quicker placenta expulsion, less bleeding, and lower stress...
January 2024: Curēus
https://read.qxmd.com/read/38431665/prenatal-mental-health-and-emotional-experiences-during-the-pandemic-associations-with-infant-neurodevelopment-screening-results
#17
JOURNAL ARTICLE
Cindy H Liu, Amanda Koire, Candice Ma, Leena Mittal, Joshua L Roffman, Carmina Erdei
BACKGROUND: This study determined whether parental mental health and emotional experiences during the prenatal period were linked to infant developmental outcomes through the Ages and Stages Questionnaire (ASQ-3) at 8-10 months. METHODS: Participants included 133 individuals who were living in the US and were pregnant or had given birth within 6 months prior to enrollment. Respondents were majority White with high education and income levels. Online surveys were administered from May 2020 to September 2021; follow-up surveys were administered from November 2020 to August 2022...
March 2, 2024: Pediatric Research
https://read.qxmd.com/read/38431012/rice-straw-derived-chitosan-enhanced-plasticizers-as-biologically-and-environmentally-friendly-alternatives-for-sustainable-materials
#18
JOURNAL ARTICLE
Shih-Chen Shi, Fu-I Lu, Chia-Yih Wang, Yan-Ting Chen, Kah-Wei Tee, Ruei-Ci Lin, Hui-Lung Tsai, Dieter Rahmadiawan
Plasticizers like Bis(2-ethylhexyl)phthalate (DEHP) are commonly used to enhance plastic properties but pose environmental and health risks. This study successfully derived plasticizers X and Y from rice straws, demonstrating efficacy in chitosan polymer coatings. Chitosan-based polymers exhibit exceptional hardness, with a value of 300 MPa, due to their enriched structure and robust chitosan bonding. This surpasses the hardness of DEHP. Zebrafish exposure over 5 days revealed that X and Y had no significant behavioral impact, while DEHP caused noticeable toxic effects...
February 29, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38414216/mother-of-all-bonds-influences-on-spatial-association-across-the-lifespan-in-capuchins
#19
JOURNAL ARTICLE
Irene Godoy, Peter Korsten, Susan E Perry
In humans, being more socially integrated is associated with better physical and mental health and/or with lower mortality. This link between sociality and health may have ancient roots: sociality also predicts survival or reproduction in other mammals, such as rats, dolphins, and non-human primates. A key question, therefore, is which factors influence the degree of sociality over the life course. Longitudinal data can provide valuable insight into how environmental variability drives individual differences in sociality and associated outcomes...
February 27, 2024: Developmental Science
https://read.qxmd.com/read/38412713/mother-to-infant-bonding-difficulties-are-associated-with-future-maternal-depression-and-child-maltreatment-behaviors-a-japanese-nationwide-longitudinal-study
#20
JOURNAL ARTICLE
Chong Chen, Sumiyo Okawa, Ryo Okubo, Kosuke Hagiwara, Tomohiro Mizumoto, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi
BACKGROUND: Mother-to-infant bonding difficulties (MIBD) are considered risk factors for postpartum depression and child-maltreatment behaviors. However, few longitudinal studies have examined this hypothesis. This study aims to explore the relationship between MIBD and subsequent maternal depression and child-maltreatment behaviors using longitudinal data from a 2021 Japanese nationwide survey. METHODS: We studied 658 first-time mothers who had given birth within the past year and had not reported postpartum depression or child-maltreatment behaviors at baseline...
February 24, 2024: Psychiatry Research
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