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https://www.readbyqxmd.com/read/28930296/the-verified-neighbor-approach-to-geoprivacy-an-improved-method-for-geographic-masking
#1
Wayne Richter
Geographic information adds a powerful component to environmental epidemiology studies but can compromise subject confidentiality. Although locations are often masked by perturbing spatial coordinates, existing masks do not ensure that the perturbation area contains a sufficient number of valid surrogates to prevent disclosure, nor are they designed to minimize perturbation while maintaining a specified level of privacy. I introduce a new approach to geoprivacy in which real property parcel data with information about land use are used to develop a pool of verified neighbors...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28928175/integrated-management-of-atrial-fibrillation-including-tailoring-of-anticoagulation-in-primary-care-study-design-of-the-all-in-cluster-randomised-trial
#2
Carline J van den Dries, Ruud Oudega, Arif Elvan, Frans H Rutten, Sjef J C M van de Leur, Henk J G Bilo, Arno W Hoes, Karel G M Moons, Geert-Jan Geersing
INTRODUCTION: In our ageing society, we are at the merge of an expected epidemic of atrial fibrillation (AF). AF management requires an integrated approach, including rate or rhythm control, stroke prevention with anticoagulation and treatment of comorbidities such as heart failure or type 2 diabetes. As such, primary care seems to be the logical healthcare setting for the chronic management of patients with AF. However, primary care has not yet played a dominant role in AF management, which has been in fact more fragmented between different healthcare providers...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28926612/correction-efficacy-of-peer-education-for-adopting-preventive-behaviors-against-head-lice-infestation-in-female-elementary-school-students-a-randomised-controlled-trial
#3
Mahdi Moshki, Fereshteh Zamani-Alavijeh, Mehdi Mojadam
[This corrects the article DOI: 10.1371/journal.pone.0169361.].
2017: PloS One
https://www.readbyqxmd.com/read/28926357/first-in-human-treatment-with-a-dendritic-cell-targeting-lentiviral-vector-expressing-ny-eso-1-lv305-induces-deep-durable-response-in-refractory-metastatic-synovial-sarcoma-patient
#4
Seth M Pollack, Hailing Lu, Sacha Gnjatic, Neeta Somaiah, Ryan B O'Malley, Robin L Jones, Frank J Hsu, Jan Ter Meulen
Effective induction of antitumor T cells is a pivotal goal of cancer immunotherapy. To this end, lentiviral vectors (LV) are uniquely poised to directly prime CD8 T-cell responses via transduction of dendritic cells in vivo and have shown promise as active cancer therapeutics in preclinical tumor models. However, until now, significant barriers related to production and regulation have prevented their widespread use in the clinic. We developed LV305, a dendritic cell-targeting, integration-deficient, replication incompetent LV from the ZVex platform, encoding the full-length cancer-testis antigen NY-ESO-1...
September 18, 2017: Journal of Immunotherapy
https://www.readbyqxmd.com/read/28925407/foxc2-coordinates-inflammation-and-browning-of-white-adipose-by-leptin-stat3-prdm16-signal-in-mice
#5
L Gan, Z Liu, F Feng, T Wu, D Luo, C Hu, C Sun
AIMS: The objective of this study is to characterize the relationship between forkhead box C2 protein (Foxc2) and leptin under adipose inflammatory response. METHODS: Lipopolysaccharide (LPS)-induced inflammatory model was conducted. Data from wild-type and ob/ob mice were used to compare the alternative role of leptin on Foxc2-mediated inflammation and browning. Transcriptional regulation and protein-protein interaction were analyzed by bioinformatics and proved by chromatin immunoprecipitation and co-immunoprecipitation experiment...
August 23, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28923492/rationale-and-design-of-the-atrial-fibrillation-health-literacy-information-technology-trial-af-litt
#6
Emily N Guhl, Courtney L Schlusser, Lori E Henault, Timothy W Bickmore, Everlyne Kimani, Michael K Paasche-Orlow, Jared W Magnani
BACKGROUND: Atrial Fibrillation (AF) is a common cardiac arrhythmia that is challenging for patients and adversely impacts health-related quality of life (HRQoL). Long-term management of AF requires that patients adhere to complex therapies, understand difficult terminology, navigate subspecialty care, and have continued symptom monitoring with the goal of preventing adverse outcomes. Continued interventions to ameliorate the patient experience of AF are essential. DESIGN: The Atrial Fibrillation health Literacy Information Technology Trial (AF-LITT; NCT03093558) is an investigator-initiated, 2-arm randomized clinical trial (RCT)...
September 15, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28923040/systematic-review-a-review-of-adolescent-behavior-change-interventions-bci-and-their-effectiveness-in-hiv-and-aids-prevention-in-sub-saharan-africa
#7
M Mwale, A S Muula
BACKGROUND: Despite sub-Saharan Africa [SSA] constituting just 12% of the world's population, the region has the highest burden of HIV with 70% of HIV infection in general and 80% of new infections among young people occuring in the region. Diverse intervention programmes have been implemented among young people but with minimal translation to behavior change. A systematic review of Behavior Change Interventions [BCI] targeting adolescents in SSA was therefore conducted with the objective of delineating this intervention vis-a-vis efficacy gap...
September 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28921418/coping-with-phantom-limb-pain
#8
Damien P Kuffler
Phantom limb pain is a chronic neuropathic pain that develops in 45-85% of patients who undergo major amputations of the upper and lower extremities and appears predominantly during two time frames following an amputation: the first month and later about 1 year. Although in most patients the frequency and intensity of pain diminish over time, severe pain persists in about 5-10%. It has been proposed that factors in both the peripheral and central nervous systems play major roles in triggering the development and maintenance of pain associated with extremity amputations...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28915908/advances-in-paediatrics-in-2016-current-practices-and-challenges-in-allergy-autoimmune-diseases-cardiology-endocrinology-gastroenterology-infectious-diseases-neonatology-nephrology-neurology-nutrition-pulmonology
#9
REVIEW
Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Silvia Montella, Sergio Bernasconi
This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated...
September 16, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28915116/a-review-of-tunisian-medicinal-plants-with-anticancer-activity
#10
Wissem Aidi Wannes, Moufida Saidani Tounsi, Brahim Marzouk
Cancer is a major public health problem in the world. The use of the medicinal plants in cancer prevention and management is frequent in Africa, especially in Tunisia, and it is transmitted from generation to generation within cultures. Many previous studies showed that a wide range of Tunisian medicinal plants exerted cytotoxic and anticancer activity. A comprehensive review was conducted to collect information from scientific journal articles, including indigenous knowledge researches, about Tunisian medicinal plants used for the prevention and management of cancer...
September 13, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28914689/the-european-journal-of-cancer-prevention-special-issue-on-joining-forces-for-better-cancer-registration-in-europe-achievements-and-perspectives
#11
Giorgia Randi, Carlo La Vecchia
No abstract text is available yet for this article.
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28906495/effects-of-a-transition-home-program-on-preterm-infant-emergency-room-visits-within-90-days-of-discharge
#12
B Vohr, E McGowan, L Keszler, M O'Donnell, K Hawes, R Tucker
OBJECTIVE: To evaluate effects of a transition home program (THP) and risk factors on emergency room (ER) use within 90 days of discharge for preterm (PT) infants <37 weeks gestation. STUDY DESIGN: This is a prospective 3-year cohort study of 804 mothers and 954 PT infants. Mothers received enhanced neonatal intensive care unit transition support services until 90 days postdischarge. Regression models were run to identify the effects of THP implementation year and risk factors on ER visits...
September 14, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28906350/the-hundred-most-cited-publications-in-microbiota-of-diabetes-research-a-bibliometric-analysis
#13
Jiaxing Tian, Min Li, Fengmei Lian, Xiaolin Tong
BACKGROUND: Bibliometric analysis is an approach to evaluate the circumstances and trends in specific research field over time and to provide inspiration in future research and policy. Researches have a tremendous increase focus on the role of the microbiota in the development of diabetes in recent years; however, there is no published literature conducting a bibliometric analysis to explore the tendency. The aim of this study was to provide a detailed evaluation of the hundred most cited articles in microbiota of diabetes research...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28902703/the-effect-of-schooling-on-age-disparate-relationships-and-number-of-sexual-partners-among-young-women-in-rural-south-africa-enrolled-in-hptn-068
#14
Marie C D Stoner, Jessie K Edwards, William C Miller, Allison E Aiello, Carolyn T Halpern, Aimée Julien, Amanda Selin, James P Hughes, Jing Wang, F Xavier Gomez-Olive, Ryan G Wagner, Catherine MacPhail, Kathleen Kahn, Audrey Pettifor
BACKGROUND: Attending school may have a strong preventative association with sexually transmitted infections among young women, but the mechanism for this relationship is unknown. One hypothesis is that students who attend school practice safer sex with fewer partners, establishing safer sexual networks that make them less exposed to infection. SETTING: We used longitudinal data from a randomized controlled trial of young women age 13-20 in the Bushbuckridge district, South Africa, to determine if the percentage of school days attended, school dropout and grade repetition are associated with having a partner five or more years older (age-disparate) and with the number of sexual partners in the previous 12 months...
September 11, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28902700/effectiveness-of-collaboration-between-emergency-department-and-intensive-care-unit-teams-on-mortality-rates-of-patients-presenting-with-critical-illness-a-systematic-review
#15
Kerchelle McDowald, Svetlana Direktor, Elizabeth A Hynes, Anna Sahadeo, Margaret E Rogers
BACKGROUND: The increasing volume of adult patients with critical illness entering emergency departments (EDs) burdens the resources of EDs worldwide. This subpopulation faces a high risk of mortality because they require specialized care which many EDs are not yet poised to deliver. An element crucial to delivering care and decreasing the mortality of critically ill patients in the ED is expert collaborative practice across disciplines. Several ED and intensive care unit (ICU) collaborative models exist including: emergency department intensive care units (EDICU) and medical emergency teams (MET)...
September 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28901334/rainfall-shocks-are-not-necessarily-a-sensitive-early-indicator-of-changes-in-wasting-prevalence
#16
N A Ledlie, H Alderman, J L Leroy, L You
Evidence on the impact of weather shocks on child nutrition focuses on linear growth retardation (stunting) and thus, associates the effect of a short-term measure (weather events) on a cumulative measure (attained height). Relatively little is known on how weather shocks predict increases in wasting in a population. This study explores whether deviation in rainfall in Ethiopia, a drought prone country, is a sensitive indicator of future increases in wasting. Around 12% of children 0-23 months were wasted, but we found no consistent association between the rainfall shock variables and child weight-for-height Z-scores...
September 13, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28895972/motivators-and-barriers-to-walking-in-older-adults-with-peripheral-artery-disease
#17
Angela J Bentley, Teresa J Kelechi
The purpose of the current review is to provide, within the context of social cognitive theory, a current description of behavioral, personal, and environmental factors that motivate or prevent an individual with peripheral artery disease (PAD) from participating in activity. A comprehensive review to explore motivators and barriers to walking in older adults with PAD was performed to help guide development of interventions to increase activity. Several databases were used for the literature review, with inclusion criteria being all study designs with samples of older adults with PAD...
September 12, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28895801/prevalence-of-sexual-assault-victimization-among-college-men-aged-18-24-a-review
#18
R Lane Forsman
PURPOSE: The current review provides summary and evaluation of prevalence data for the sexual victimization of college men ages 18 - 24. METHODS: Potential studies were selected by searching electronic bibliographic databases. Studies were initially selected for inclusion if they (1) assessed prevalence rates of sexual victimization on college campuses and (2) were published in a scholarly journal (3) in the English language. Utilizing this strategy, 3,973 studies were initially identified, of which 5 underwent complete review...
September 12, 2017: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/28892555/stigma-of-hiv-testing-on-online-hiv-forums-self-stigma-and-the-unspoken
#19
Chia-Ling Lynn Ho, Wenjing Pan, Laramie D Taylor
Most studies examining HIV-related content in web forums have revolved around the most frequently used terms in HIV-related messages and topics, as well as the supportive nature of those messages. The current study explored barriers that prevent individuals from seeking HIV testing (specifically stigma). The current study analyzed a total of 210 threads and 319 posts, yielding 13 threads that revealed how individuals self-stigmatize and expressed how the fear of being diagnosed prevented them from seeking HIV testing...
September 11, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28890847/the-contribution-of-nintendo-wii-fit-series-in-the-field-of-health-a-systematic-review-and-meta-analysis
#20
Julien Tripette, Haruka Murakami, Katie Rose Ryan, Yuji Ohta, Motohiko Miyachi
BACKGROUND: Wii Fit was originally designed as a health and fitness interactive training experience for the general public. There are, however, many examples of Wii Fit being utilized in clinical settings. This article aims to identify the contribution of Wii Fit in the field of health promotion and rehabilitation by: (1) identifying the health-related domains for which the Wii Fit series has been tested, (2) clarifying the effect of Wii Fit in those identified health-related domains and (3) quantifying this effect...
2017: PeerJ
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