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https://www.readbyqxmd.com/read/28550544/-non-pharmacological-migraine-treatment-a-practice-oriented-summary
#1
REVIEW
Thomas Dresler, Bianca Meyer, Peter Kropp
No abstract text is available yet for this article.
June 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/28550480/characteristics-associated-with-quality-of-life-among-people-with-drug-resistant-epilepsy
#2
Leone Ridsdale, Gabriella Wojewodka, Emily Robinson, Sabine Landau, Adam Noble, Stephanie Taylor, Mark Richardson, Gus Baker, Laura H Goldstein
Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. We recruited 404 adults attending specialist clinics, with at least two seizures in the prior year and measured their self-reported seizure frequency, co-morbidity, psychological distress, social characteristics, including self-mastery and stigma, and epilepsy-specific QoL (QOLIE-31-P)...
May 26, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28541026/advances-in-the-management-of-diabetic-neuropathy
#3
Tamás Várkonyi, Anna Körei, Zsuzsanna Putz, Tímea Martos, Katalin Keresztes, Csaba Lengyel, Szabolcs Nyiraty, Alin Stirban, György Jermendy, Péter Kempler
The authors review current advances in the therapy of diabetic neuropathy. The role of glycaemic control and management of cardiovascular risk factors in the prevention and treatment of neuropathic complications are discussed. As further options of pathogenetic ally oriented treatment, recent knowledge on benfotiamine and alpha-lipoic acid is comprehensively reviewed. Alpha-lipoic acid is a powerful antioxidant and clinical trials have proven its efficacy in ameliorating neuropathic signs and symptoms. Benfotiamine acts via the activation of transketolase and thereby inhibits alternative pathways triggered by uncontrolled glucose influx in the cells comprising polyol, hexosamine, protein-kinase-C pathways and formation of advanced glycation end products...
May 25, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28540765/an-update-on-pediatric-bronchiectasis
#4
Danielle F Wurzel, Anne B Chang
The prevalence and awareness of bronchiectasis not related to cystic fibrosis (CF) is increasing and it is now recognized as a major cause of respiratory morbidity, mortality and healthcare utilization worldwide. The need to elucidate the early origins of bronchiectasis is increasingly appreciated and has been identified as an important research priority. Current treatments for pediatric bronchiectasis are limited to antimicrobials, airway clearance techniques and vaccination. Several new drugs targeting airway inflammation are currently in development...
May 25, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28540224/erectile-dysfunction-therapy-in-countries-where-implant-is-economically-not-feasible
#5
REVIEW
Adrián M Garza-Gangemi, Mariano Sotomayor-de Zavaleta
Erectile dysfunction (ED), a frequent complaint in the primary care setting, is strongly associated with obesity, cigarette smoking and other common cardiovascular risk factors like hypertension, diabetes mellitus (DM), lipid disorders and the metabolic syndrome. The prevalence of these cardiovascular disorders is rising at staggering rates in most Latin American countries. ED is a symptom that mainly affects economically productive men (40-70 years of age) potentially causing major psychosocial repercussions and reduced quality of life...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28539993/effectiveness-of-non-pharmacological-interventions-on-stereotyped-and-repetitive-behaviors-of-pre-school-children-with-autism-a-systematic-review
#6
REVIEW
Hadi Zarafshan, Maryam Salmanian, Soudeh Aghamohammadi, Mohammad Reza Mohammadi, Seyed-Ali Mostafavi
INTRODUCTION: The present study aimed to review the literature on non-pharmacological interventions used to treat stereotyped and repetitive behaviors by a systematic method. METHODS: Two authors independently performed a search strategy on Medline/PubMed, Scopus and PsycINFO on English articles published up to April 23, 2014 with relevant search keywords. We also reviewed the bibliographies of retrieved articles and conference proceedings to obtain additional citations and references...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539119/towards-the-concept-of-disease-modifier-in-post-stroke-or-vascular-cognitive-impairment-a-consensus-report
#7
Régis Bordet, Ralf Ihl, Amos D Korczyn, Giuseppe Lanza, Jelka Jansa, Robert Hoerr, Alla Guekht
BACKGROUND: Vascular cognitive impairment (VCI) is a complex spectrum encompassing post-stroke cognitive impairment (PSCI) and small vessel disease-related cognitive impairment. Despite the growing health, social, and economic burden of VCI, to date, no specific treatment is available, prompting the introduction of the concept of a disease modifier. CONSENSUS AND SUGGESTIONS: Within this clinical spectrum, VCI and PSCI remain advancing conditions as neurodegenerative diseases with progression of both vascular and degenerative lesions accounting for cognitive decline...
May 24, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28537354/the-use-of-transcutaneous-electrical-nerve-stimulation-after-total-knee-arthroplasty-a-prospective-randomized-controlled-trial
#8
Deepak Ramanathan, Anas Saleh, Alison K Klika, Carlos A Higuera, Wael K Barsoum
INTRODUCTION: Multimodal pain management is used after total knee arthroplasty (TKA) to reduce opioid intake. Transcutaneous electrical nerve stimulation (TENS) has generated much interest as a non-pharmacologic, patient-controlled therapy. The aims of this study were to evaluate the efficacy of TENS in reducing opioid intake and improving recovery after TKA. MATERIALS AND METHODS: This was a prospective, parallel-group, double-blinded, randomized trial of patients receiving femoral nerve catheter block with allocation to either active or placebo TENS device groups...
May 24, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28536365/new-insights-into-the-pathophysiology-and-treatment-of-fibromyalgia
#9
REVIEW
Tobias Schmidt-Wilcke, Martin Diers
Fibromyalgia is characterized by chronic widespread pain and several additional symptoms such as fatigue, cognitive dysfunction, depressive episodes, and anxiety. The underlying pathophysiology of fibromyalgia is still poorly understood, and treatment is often unsatisfactory. Current research provides evidence for altered pain processing in chronic pain patients, and specifically in fibromyalgia patients, possibly based on altered functional connectivity and brain chemistry in brain regions within the pain processing system...
May 13, 2017: Biomedicines
https://www.readbyqxmd.com/read/28535406/anhedonia-predicts-poor-psychosocial-functioning-results-from-a-large-cohort-of-patients-treated-for-major-depressive-disorder-by-general-practitioners
#10
F Vinckier, D Gourion, S Mouchabac
BACKGROUND: Anhedonia is a core symptom of major depression and a key prognostic factor that is often poorly explored in clinical trials of major depressive disorder (MDD). Beyond symptomatic remission, psychosocial functioning also reveals difficulty in achieving remission in patients with MDD. The main objective of this study was to explore the interrelationships between social functioning and anhedonia on a longitudinal basis. METHODS: In total, 1570 outpatients treated for MDD with agomelatine were included...
March 8, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28533729/anmco-gicr-iacpr-sici-gise-consensus-document-the-clinical-management-of-chronic-ischaemic-cardiomyopathy
#11
Carmine Riccio, Michele Massimo Gulizia, Furio Colivicchi, Andrea Di Lenarda, Giuseppe Musumeci, Pompilio Massimo Faggiano, Maurizio Giuseppe Abrignani, Roberta Rossini, Francesco Fattirolli, Serafina Valente, Gian Francesco Mureddu, Pier Luigi Temporelli, Zoran Olivari, Antonio Francesco Amico, Giancarlo Casolo, Claudio Fresco, Alberto Menozzi, Federico Nardi
Stable coronary artery disease (CAD) is a clinical entity of great epidemiological importance. It is becoming increasingly common due to the longer life expectancy, being strictly related to age and to advances in diagnostic techniques and pharmacological and non-pharmacological interventions. Stable CAD encompasses a variety of clinical and anatomic presentations, making the identification of its clinical and anatomical features challenging. Therapeutic interventions should be defined on an individual basis according to the patient's risk profile...
May 2017: European Heart Journal Supplements: Journal of the European Society of Cardiology
https://www.readbyqxmd.com/read/28533058/music-therapy-for-symptom-management-after-autologous-stem-cell-transplantation-results-from-a-randomized-study
#12
Debbie Bates, Brian Bolwell, Navneet S Majhail, Lisa Rybicki, Melissa Yurch, Donna Abounader, Joseph Kohuth, Shannon Jarancik, Heather Koniarczyk, Linda McLellan, Jane Dabney, Christine Lawrence, Lisa Gallagher, Matt Kalaycio, Ronald Sobecks, Robert Dean, Brian Hill, Brad Pohlman, Betty K Hamilton, Aaron T Gerds, Deepa Jagadeesh, Hien D Liu
High-dose chemotherapy followed by autologous stem cell transplant (ASCT) is frequently performed in patients with hematologic malignancies. ASCT can result in significant nausea, pain, and discomfort. Supportive care has improved and pharmacologic therapies are frequently employed, but with limitations. Music has been demonstrated to improve nausea and pain in patients undergoing chemotherapy but few data are available regarding the effects of music therapy in the transplant setting. In a prospective study, patients with lymphoma or multiple myeloma undergoing ASCT were randomized to receive either interactive music therapy (MT) with a board-certified music therapist or no music therapy (No MT)...
May 19, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28533043/-dementia-and-non-pharmacological-therapy-the-effectiveness-of-play
#13
Cédric Gueyraud, Marie Anaut, Stéphane Sanchez, Philippe Denormandie, Anthony Bathsavanis, Pierre Krolak-Salmon
A study was carried out to look into the effectiveness of play and the ways it can be used in the treatment of Alzheimer's disease. An intervention founded on the principal of a recreational setting, taking into account the choice of objects, the layout of the space and the role of the professional, could present itself as a form of therapeutic mediation adapted to this pathology. This study shows that play helps to reduce the behavioural problems of residents with Alzheimer's disease, and boosted their wellbeing and quality of life...
May 2017: Soins. Gérontologie
https://www.readbyqxmd.com/read/28527958/treadmill-exercise-produces-neuroprotective-effects-in-a-murine-model-of-parkinson-s-disease-by-regulating-the-tlr2-myd88-nf-%C3%AE%C2%BAb-signaling-pathway
#14
Jung-Hoon Koo, Yong-Chul Jang, Dong-Ju Hwang, Hyun-Seob Um, Nam-Hee Lee, Jae-Hoon Jung, Joon-Yong Cho
Parkinson's disease (PD) is characterized by progressive dopamine depletion and a loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Treadmill exercise is a promising non-pharmacological approach for reducing the risk of PD and other neuroinflammatory disorders, such as Alzheimer's disease. The goal of this study was to investigate the effects of treadmill exercise on α-synuclein-induced neuroinflammation and neuronal cell death in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of PD...
May 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28527163/pharmacotherapy-of-insomnia-and-current-updates
#15
REVIEW
Arup Kumar Misra, Pramod Kumar Sharma
Insomnia is highly prevalent and is associated with a range of psychological, psychiatric, and medical conditions. Insomnia affects health by influencing cognitive, emotional and social functioning. Circadian and sleep homeostatic processes play an important role in insomnia development and its maintenance. Several efficacious treatments, both pharmacologic and non-pharmacologic, exist for the management of insomnia. Among non-pharmacologic treatments including stimulus control therapy, sleep restriction, relaxation, sleep hygiene and cognitive therapy have been shown to be efficacious...
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28527085/the-use-of-nutraceutics-in-children-s-and-adolescent-s-headache
#16
R Sangermani, A Boncimino
Nutraceutics are the most used non-pharmacological remedies for migraine's prophylaxis in children and adolescents. Doctors interested in use of nutraceuticals for a complete treatment of children's headache should be adequately informed on this treatments' efficacy and safety. Actually there is a lack of official guidelines about use of nutraceuticals in migraine's prevention in children and adolescent and there are few studies with limited efficacy evidences. The most used nutraceuticals for adolescent's and children's headache prophylaxis are: magnesium, coenzyme Q10, riboflavin, butterbur, feverfew and melatonin...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527071/cost-of-medication-overuse-headache-in-italian-patients-at-the-time-point-of-withdrawal-a-retrospective-study-based-on-real-data
#17
Domenico D'Amico, Licia Grazzi, Marcella Curone, Matilde Leonardi, Alberto Raggi
The objective was to assess the cost of Medication Overuse Headache (MOH) at the time-point of withdrawal treatment. We implemented a protocol in which both direct and indirect cost were directly gathered from patients and referred to the previous three months. Direct costs were calculated by medications for acute treatment and prophylaxis, diagnostic procedures, visits, complementary treatments, informal care. Indirect costs were referred to missed workdays and workdays with reduced productivity: we asked patients to refer their salaries and to rate the overall level of performance in days worked with reduced productivity, and we calculated indirect costs on this basis...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527067/usefulness-of-nutraceuticals-in-migraine-prophylaxis
#18
Florindo D'Onofrio, Simona Raimo, Daniele Spitaleri, Gerardo Casucci, Gennaro Bussone
Several studies have supported the efficacy of complementary and alternative medicine approaches (physical, behavioral and nutraceutical therapies) in the treatment of headache disorders. Nutraceutical treatment consists of taking vitamins, supplements (magnesium, riboflavin, coenzyme Q10, and alpha lipoic acid) and herbal preparations (feverfew and butterbur), and its usage is frequently determined by dissatisfaction with conventional medical therapies. There is a growing body of research on nutraceutical use for migraine prophylaxis...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28523698/survey-among-critical-care-nurses-and-physicians-about-delirium-management
#19
Peter Nydahl, Michael Dewes, Rolf Dubb, Carsten Hermes, Arnold Kaltwasser, Susanne Krotsetis, Rebecca von Haken
BACKGROUND: Delirium is a serious complication in patients in intensive care units. Previous surveys on delirium management in daily practice showed low adherence to published guidelines. AIM: To evaluate delirium management in nurses and physicians working in intensive care units in German-speaking countries and to identify related differences between nurses and physicians. DESIGN: The study used an open online survey with multiple-choice responses...
May 18, 2017: Nursing in Critical Care
https://www.readbyqxmd.com/read/28523574/medical-management-of-pain-in-chronic-pancreatitis
#20
REVIEW
Vikesh K Singh, Asbjørn M Drewes
The medical management of pain in chronic pancreatitis continues to pose significant challenges for clinicians caring for these patients. There are increasing data, suggesting that pain in chronic pancreatitis is largely due to peripheral and central sensitization that evolves, over time, as a result of nociceptive afferent associated with chronic inflammation and fibrosis of the pancreas. In many instances, patients rapidly progress to requiring opioid analgesics for the adequate treatment of pain despite the unequivocal risks associated with the long-term use of these drugs...
May 18, 2017: Digestive Diseases and Sciences
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