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https://www.readbyqxmd.com/read/29161806/young-academic-urologist-benign-prostatic-obstruction-nomogram-predicts-clinical-outcome-in-patients-treated-with-transurethral-resection-of-prostate-an-italian-cohort-study
#1
Cosimo DE Nunzio, Riccardo Lombardo, Antonio Nacchia, Marianna Deroma, Hassan Alkhatatbeh, Aldo Brassetti, Andrea Tubaro
BACKROUND: Aim of our study was to test the Young Academic Urologist nomogram for the prediction of transurethral resection of prostate outcome in patients with lower urinary tract symptoms and benign prostatic enlargement. METHODS: Between April 2014 and March 2016, a consecutive series of patients with lower urinary tract symptoms undergoing trans-urethral resection of prostate in one center were enrolled. At baseline patients were assessed with international prostate symptom score, prostate specific antigen, prostate volume, transitional zone volume, maximal urinary flow rate and post void residual urine...
November 21, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29161795/superior-mesenteric-artery-syndrome-combined-with-renal-nutcracker-syndrome-in-a-young-male-a-case-report
#2
Myung Jin Oh
Superior mesenteric artery (SMA) syndrome is one of the rare causes of small bowel obstruction. It develops following a marked decrease in the angle between SMA and the abdominal aorta due to weight loss, anatomical anomalies, or following surgeries. Nutcracker syndrome in the left renal vein may also occur following a decrease in the aortomesenteric angle. Though SMA syndrome and renal nutcracker syndrome share the same pathogenesis, concurrent development has rarely been reported. Herein, we report a 23-year-old healthy male diagnosed with SMA syndrome and renal nutcracker syndrome due to severe weight reduction...
November 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29161777/structure-based-design-and-evaluation-of-synthetic-porphyrin-derivatives-as-g-quadruplex-stabilizing-anticancer-agents
#3
R N Bhadane, D B Meshram, R M Gilhotra
G-quadruplex structures formed in telomeres and proto-oncogene represent a potentially useful target for anticancer drugs. Stabilization of this arrangement may inhibit the further action of different enzymes involved in cancer cell immortalization. In present work structure based drug design and synthesis was carried out on series of meso-substituted porphyrin analogues. The interaction of porphyrin derivatives with G-quadruplex DNA has been explored by virtual screening procedure. Some of the potential binding agents were then synthesized and evaluated in-vitro by MTT and PCR stop assay...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29161691/failure-to-thrive-in-the-context-of-carney-complex
#4
Amit Tirosh, Adi Auerbach, Belen Bonella, Phaedon D Zavras, Elena Belyavskaya, Charalampos Lyssikatos, Karen Meir, Ram Weiss, Hagit Daum, Maya B Lodish, David Gillis, Constantine A Stratakis
BACKGROUND/AIMS: Carney complex (CNC) is a rare syndrome associated with multiple tumors and several other unique manifestations. We describe the clinical, genetic, and laboratory findings in a cohort of patients with CNC and failure to thrive (FTT). METHODS: A retrospective case series of pediatric patients with CNC presenting with FTT. RESULTS: We describe a patient with infantile Cushing syndrome (CS) who presented with severe FTT and liver disease; the patient was subsequently diagnosed with CNC...
November 21, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29161655/the-association-between-ambient-temperature-and-mortality-in-south-africa-a-time-series-analysis
#5
Noah Scovronick, Francesco Sera, Fiorella Acquaotta, Diego Garzena, Simona Fratianni, Caradee Y Wright, Antonio Gasparrini
BACKGROUND: There is an extensive literature describing temperature-mortality associations in developed regions, but research from developing countries, and Africa in particular, is limited. METHODS: We conducted a time-series analysis using daily temperature data and a national dataset of all 8.8 million recorded deaths in South Africa between 1997 and 2013. Mortality and temperature data were linked at the district municipality level and relationships were estimated with a distributed lag non-linear model with 21 days of lag, and pooled in a multivariate meta-analysis...
November 18, 2017: Environmental Research
https://www.readbyqxmd.com/read/29161647/simple-synthesis-of-self-supported-hierarchical-aupd-alloyed-nanowire-networks-for-boosting-electrocatalytic-activity-toward-formic-acid-oxidation
#6
Tao Yuan, Hong-Yan Chen, Xiaohong Ma, Jiu-Ju Feng, Pei-Xin Yuan, Ai-Jun Wang
Herein, self-supported hierarchical AuPd alloyed interconnected nanowire networks (AuPd NCNs) were fabricated by a one-pot co-reduction method. Theophylline was acted as the capping and structure-directing agents. The product was mainly characterized by a series of techniques such as transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The hierarchical nanostructures had the enlarged electrochemically active surface area (EASA), and the enhanced catalytic activity toward formic acid oxidation reaction (FAOR) and strengthened poisoning tolerance for poisoning CO-like intermediates by cyclic voltammetry and chronoamperometry, which outperformed commercial Pd black catalyst...
November 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29161601/characterizing-emission-rates-of-regulated-pollutants-from-model-year-2012-heavy-duty-diesel-vehicles-equipped-with-dpf-and-scr-systems
#7
Yu Jiang, Jiacheng Yang, David Cocker, Georgios Karavalakis, Kent C Johnson, Thomas D Durbin
The regulated emissions of five 2012 and newer, low-mileage, heavy-duty Class 8 diesel trucks equipped with diesel particulate filters (DPFs) and selective catalytic reduction (SCR) systems were evaluated over test cycles representing urban, highway, and stop-and-go driving on a chassis dynamometer. NOx emissions over the Urban Dynamometer Driving Schedule (UDDS) ranged from 0.495 to 1.363g/mi (0.136 to 0.387g/bhp-hr) for four of the normal emitting trucks. For those trucks, NOx emissions were lowest over the cruise (0...
November 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29161576/unraveling-physiological-biochemical-and-molecular-mechanisms-involved-in-olive-olea-europaea-l-cv-ch%C3%A3-toui-tolerance-to-drought-and-salt-stresses
#8
Mariem Ben Abdallah, Dalila Trupiano, Antonella Polzella, Elena De Zio, Mauro Sassi, Andrea Scaloni, Mokhtar Zarrouk, Nabil Ben Youssef, Gabriella Stefania Scippa
Olive (Olea europaea L.) is an economically important crop for the Mediterranean basin, where prolonged drought and soil salinization may occur. This plant has developed a series of mechanisms to tolerate and grow under these adverse conditions. By using an integrated approach, we described in Chétoui olive cultivar the changes in plant growth, oxidative damage and osmolyte accumulation in leaves, in combination with corresponding changes in physiological parameters and proteome. Our results showed, under both stress conditions, a greater growth reduction of the aboveground plant organs than of the underground counterparts...
November 10, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29161573/decentralized-biorefinery-for-lignocellulosic-biomass-integrating-anaerobic-digestion-with-thermochemical-conversion
#9
Chayanon Sawatdeenarunat, Hyungseok Nam, Sushil Adhikari, Shihwu Sung, Samir Kumar Khanal
Anaerobic digestion (AD) of lignocellulosic biomass i.e. Napier grass (Pennisetum purpureum), was investigated via a series of batch and bench-scale experiments. Two semi-continuous bench-scale horizontal bioreactors were operated in parallel for nearly 300 days, and the reactors were able to handle the organic loading rate (OLR) up to 6 kg volatile solids (VS)/m(3)-d, which was among the highest OLR reported in the literature for lignocellulosic biomass. Hemicellulose was the main structural carbohydrate of lignocellulosic biomass per unit respective mass (dry weight) basis contributing to methane production...
November 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29161529/developing-a-serious-videogame-for-preteens-to-motivate-hpv-vaccination-decision-making-land-of-secret-gardens
#10
Joan R Cates, Bernard F Fuemmeler, Sandra J Diehl, Laurie L Stockton, Jeannette Porter, Chioma Ihekweazu, Arshya S Gurbani, Tamera Coyne-Beasley
INTRODUCTION: Vaccination against human papillomavirus (HPV) is routinely recommended for ages 11-12, yet in 2016 only 49.5% of women and 37.5% of men had completed the three-dose series in the United States. Offering information and cues to action through a serious videogame for preteens may foster HPV vaccination awareness, information seeking, and communication. MATERIALS AND METHODS: An iterative process was used to develop an interactive videogame, Land of Secret Gardens...
November 21, 2017: Games for Health
https://www.readbyqxmd.com/read/29161508/design-and-fabrication-of-wettability-gradients-with-tunable-profiles-through-degrafting-organosilane-layers-from-silica-surfaces-by-tetrabutylammonium-fluoride
#11
Jason R Miles, Spencer L Schlenker, Yeongun Ko, Rohan R Patil, Balaji M Rao, Jan Genzer
Surface-bound wettability gradients allow for a high-throughput approach to evaluate surface interactions for many biological and chemical processes. Here we describe the fabrication of surface wettability gradients on flat surfaces by a simple, two-step procedure that permits precise tuning of the gradient profile. This process involves the deposition of homogeneous silane SAMs followed by the formation of a surface coverage gradient through the selective removal of silanes from the substrate. Removal of silanes from the surface is achieved by using tetrabutylammonium fluoride which cleaves selectively the Si-O bonds at the headgroup of the silane...
November 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29161483/-spatio-temporal-analysis-of-the-biophysical-and-ecological-conditions-of-triatoma-dimidiata-hemiptera-reduviidae-triatominae-in-the-northeast-region-of-colombia
#12
Jaime Badel-Mogollón, Laura Rodríguez-Figueroa, Gabriel Parra-Henao
INTRODUCTION: Due to the lack of information regarding biophysical and spatio-temporal conditions (hydrometheorologic and vegetal coverage density) in areas with Triatoma dimidiata in the Colombian departments of Santander and Boyacá, there is a need to elucidate the association patterns of these variables to determine the distribution and control of this species. OBJECTIVE: To make a spatio-temporal analysis of biophysical variables related to the distribution of T...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29161368/management-of-cardiac-tamponade-in-catheter-ablation-of-atrial-fibrillation-single-centre-15%C3%A2-year-experience-on-5222-procedures
#13
Rikuta Hamaya, Shinsuke Miyazaki, Hiroshi Taniguchi, Shigeki Kusa, Hiroaki Nakamura, Hitoshi Hachiya, Takatsugu Kajiyama, Tomonori Watanabe, Miyako Igarashi, Kenzo Hirao, Yoshito Iesaka
Aims: Cardiac tamponade during atrial fibrillation (AF) ablation is infrequent but potentially fatal. This study aimed to retrospectively investigate the incidence, management, and outcomes of tamponade in large patient series. Methods and results: The study analysed 5222 AF ablation procedures in 3483 patients between 2002 and 2016 under a heparin-bridge anticoagulation protocol. Cardiac tamponade occurred in 51 procedures/patients, and the incidence was 0...
November 17, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29161336/efficacy-of-electrical-stimulation-of-the-occipital-nerve-in-intractable-primary-headache-disorders-a-systematic-review-with-meta-analyses
#14
Robert T Cadalso, John Daugherty, Caron Holmes, Saravanan Ram, Reyes Enciso
AIMS: To determine the efficacy of occipital nerve stimulation (ONS) in reducing the intensity, duration, and frequency of medically intractable primary headaches. METHODS: A systematic review was carried out by searching three electronic databases: the Cochrane Library, MEDLINE via PubMed, and Web of Science. Randomized controlled trials (RCTs) and case series were eligible for inclusion. RCTs were assessed for quality of evidence by using the Cochrane Risk of Bias and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tools...
November 21, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29161311/expression-and-regulation-of-atl9-an-e3-ubiquitin-ligase-involved-in-plant-defense
#15
Fengyan Deng, Tingwei Guo, Mitchell Lefebvre, Steven Scaglione, Christopher J Antico, Tao Jing, Xin Yang, Weixing Shan, Katrina M Ramonell
Plants are continually exposed to a variety of pathogenic organisms, including bacteria, fungi and viruses. In response to these assaults, plants have developed various defense pathways to protect themselves from pathogen invasion. An understanding of the expression and regulation of genes involved in defense signaling is essential to controlling plant disease. ATL9, an Arabidopsis RING zinc finger protein, is an E3 ubiquitin ligase that is induced by chitin and involved in basal resistance to the biotrophic fungal pathogen, Golovinomyces cichoracearum (G...
2017: PloS One
https://www.readbyqxmd.com/read/29161225/from-sexual-desire-discrepancies-to-desirable-sex-creating-the-optimal-connection
#16
Peggy J Kleinplatz, Maxime Charest, Shannon Lawless, Marlene Neufeld, Robert Neufeld, Danielle Pratt, A Dana Ménard, Bogdan Buduru, Lianne Rosen
Beginning in 2005, our team conducted a series of studies on optimal sexual experiences. We have applied our findings to develop a group therapy intervention for couples presenting with low sexual desire/frequency and sexual desire discrepancy. The goal was to improve the quality of erotic intimacy by focusing on such elements as being fully embodied during sex, increasing authenticity, trustworthiness and vulnerability. Twenty-eight heterosexual individuals (14 couples) were seen in 16 hours of couples group therapy...
November 21, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29161198/a-systematic-review-of-factors-influencing-human-papillomavirus-vaccination-among-immigrant-parents-in-the-united-states
#17
Kyounghae Kim, Anna-Rae LeClaire
To critically appraise factors influencing human papillomavirus (HPV) vaccination among immigrant parents in the United States, a comprehensive search of electronic databases and reference lists was conducted. The findings from 22 articles were ordered based on a socio-ecological model. About 30% of children initiated and 14% completed a 3-dose series. Correlates of HPV vaccine initiation rates included lack of information, concerns about vaccine safety and promiscuity, providers' recommendations, school mandates, financial issues, immigration laws, and living in disadvantaged neighborhoods...
November 21, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29161187/network-mapping-with-gimme
#18
Adriene M Beltz, Kathleen M Gates
Network science is booming! While the insights and images afforded by network mapping techniques are compelling, implementing the techniques is often daunting to researchers. Thus, the aim of this tutorial is to facilitate implementation in the context of GIMME, or group iterative multiple model estimation. GIMME is an automated network analysis approach for intensive longitudinal data. It creates person-specific networks that explain how variables are related in a system. The relations can signify current or future prediction that is common across people or applicable only to an individual...
November 2017: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/29161183/epitope-mapping-of-monoclonal-antibody-pmab-38-against-dog-podoplanin
#19
Yao-Wen Chang, Shinji Yamada, Mika K Kaneko, Yukinari Kato
Podoplanin (PDPN), a type I transmembrane sialoglycoprotein, is extensively expressed by normal lymphatic endothelial cells, renal podocytes, and pulmonary type I alveolar cells. Nevertheless, increased expression of PDPN in malignant tumors not only associates with poor prognosis but also facilitates hematogenous metastasis through interaction with C-type lectin-like receptor-2 presented on platelets, followed by PDPN-mediated platelet activation. We previously reported a novel PMab-38 antibody, an anti-dog PDPN (dPDPN) monoclonal antibody, which specifically recognizes PDPN in squamous cell carcinomas melanomas and cancer-associated fibroblasts in canine cancer tissues...
November 21, 2017: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
https://www.readbyqxmd.com/read/29161115/hip-arthroscopic-surgery-for-femoroacetabular-impingement-with-capsular-management-factors-associated-with-achieving-clinically-significant-outcomes
#20
Gregory L Cvetanovich, Alexander E Weber, Benjamin D Kuhns, Jennifer Alter, Joshua D Harris, Richard C Mather, Shane J Nho
BACKGROUND: There has been increasing interest in defining clinically meaningful outcomes in patient reported outcomes following orthopaedic surgery. Little is known about the factors associated with clinically meaningful outcomes after hip arthroscopy for femoroacetabular impingement. STUDY DESIGN: Case-control study; Level of evidence, 3. PURPOSE: To report on a large, prospectively collected consecutive series of patients who underwent comprehensive arthroscopic treatment of femoroacetabular impingement (FAI) and capsular management with greater than 2-year follow-up...
November 1, 2017: American Journal of Sports Medicine
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