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https://www.readbyqxmd.com/read/29778087/midwifery-management-of-pregnant-women-who-are-obese
#1
Margi Reither, Elaine Germano, Michele DeGrazia
INTRODUCTION: Obesity is associated with increased risks for adverse health outcomes during and after pregnancy in both the woman with obesity and her infant. This study was designed to investigate midwifery management of pregnant women with obesity. METHODS: Certified midwives and certified nurse-midwives who were members of the American College of Nurse-Midwives were sent a survey. The survey instrument was divided into 4 sections: demographic characteristics; practice guidelines and protocols; the role of the 2015 Levels of Maternal Care guidelines for referral, including transfer to a higher level of care; and factors that influence management of pregnant women with obesity...
May 19, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29778086/pelvic-floor-physical-therapy-and-women-s-health-promotion
#2
REVIEW
Samantha Lawson, Ashley Sacks
Pelvic floor dysfunction is defined as abnormal function of the pelvic floor and includes conditions that can have significant adverse impacts on a woman's quality of life, including urinary incontinence (stress, urge, and mixed), fecal incontinence, pelvic organ prolapse, sexual dysfunction, diastasis recti abdominis, pelvic girdle pain, and chronic pain syndromes. Women's health care providers can screen for, identify, and treat pelvic floor dysfunction. This article examines the case of a woman with multiple pelvic-floor-related problems and presents the evidence for the use of pelvic floor physical therapy (PFPT) for pregnancy-related pelvic floor dysfunction...
May 19, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29778081/molecular-aspect-of-silver-nanoparticles-regulated-embryonic-development-in-zebrafish-danio-rerio-by-oct-4-expression
#3
Biplab Sarkar, Suresh K Verma, Javed Akhtar, Surya Prakash Netam, Sanjay Kr Gupta, Pritam Kumar Panda, Koel Mukherjee
With the enhancement of commercial manifestation of silver nanoparticles, concerned has risen on their accumulation in aquatic system and consequent effects on fish development and metabolism. In this study, experiments were conducted to assess the impacts of silver nanoparticles on early life cycles of fish considering Zebrafish (Danio rerio) as experimental model. Silver nanoparticles were synthesized through chemical reduction method and characterized through UV-visible spectroscopy, dynamic light scattering (DLS), and HR-TEM...
May 4, 2018: Chemosphere
https://www.readbyqxmd.com/read/29778066/transport-of-trace-organic-compounds-through-novel-forward-osmosis-membranes-role-of-membrane-properties-and-the-draw-solution
#4
Marc Sauchelli, Giuseppe Pellegrino, Arnout D'Haese, Ignasi Rodríguez-Roda, Wolfgang Gernjak
Forward osmosis (FO) offers to be a very promising technology for the removal of trace organic compounds (TrOCs) from contaminated wastewater, and with the recent developments in FO membranes, the effect of both a higher water flux and reverse salt flux on the rejection of TrOCs needs to be explored. In this study two novel thin-film composite (TFC) membranes with greater water permeability and selectivity than the benchmark cellulose tri-acetate (CTA) membrane were compared at bench-scale in terms of TrOCs permeability...
May 5, 2018: Water Research
https://www.readbyqxmd.com/read/29778061/syntactic-and-semantic-restrictions-on-morphological-recomposition-meg-evidence-from-greek
#5
K Neophytou, C Manouilidou, L Stockall, A Marantz
Complex morphological processing has been extensively studied in the past decades. However, most of this work has either focused on only certain steps involved in this process, or it has been conducted on a few languages, like English. The purpose of the present study is to investigate the spatiotemporal cortical processing profile of the distinct steps previously reported in the literature, from decomposition to re-composition of morphologically complex items, in a relatively understudied language, Greek. Using magnetoencephalography, we confirm the role of the fusiform gyrus in early, form-based morphological decomposition, we relate the syntactic licensing of stem-suffix combinations to the ventral visual processing stream, somewhat independent from lexical access for the stem, and we further elucidate the role of orbitofrontal regions in semantic composition...
May 16, 2018: Brain and Language
https://www.readbyqxmd.com/read/29778055/new-insights-into-the-effects-of-support-matrix-on-the-removal-of-organic-micro-pollutants-and-the-microbial-community-in-constructed-wetlands
#6
Liang Zhang, Tao Lyu, Carlos Andrés Ramírez Vargas, Carlos A Arias, Pedro N Carvalho, Hans Brix
Constructed wetlands (CWs) are an eco-friendly and cost-effective technology to remove organic micro-pollutants (OMPs) from wastewater. The support matrix is an important component in CWs as it has a primary role in the growth and development of plants and microbes. However, the roles of the support matrix in CWs in removing OMPs have not been systematically studied. Therefore, in this study, six common materials (sand, zeolite, blast iron slag, petcoke, polonite and crushed autoclaved aerated concrete (CAAC)) as support matrixes were firstly investigated by batch tests to explore their adsorption capacities to selected OMPs (ibuprofen, iohexol, tebuconazole and imazalil)...
May 16, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29778053/attention-deficit-hyperactivity-disorder-symptoms-and-happiness-among-adults-in-the-general-population
#7
Andrew Stickley, Ai Koyanagi, Hidetoshi Takahashi, Vladislav Ruchkin, Yosuke Inoue, Aki Yazawa, Yoko Kamio
Despite an increasing focus on the role of mood and emotions in attention-deficit/hyperactivity disorder (ADHD), as yet, there has been comparatively little research on positive emotions. To address this research gap, the current study examined the association between ADHD symptoms and happiness using data from the 2007 Adult Psychiatric Morbidity Survey. The analytic sample comprised 7274 adults aged 18 and above residing in private households in England. Information was collected on ADHD symptoms using the Adult ADHD Self-Report Scale (ASRS) Screener, while happiness was assessed with a single (3-point) measure...
May 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29778041/the-efficacy-of-vitamin-d-in-multiple-sclerosis-a-meta-analysis
#8
REVIEW
Chao Zheng, Liang He, Lingling Liu, Jie Zhu, Tao Jin
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelination disorder in the central nervous system (CNS) leading to a high level of neurological disability. The pathogenesis of MS remains largely unknown, which explains the lack of significant efficacy of therapy in MS. Vitamin D deficiency is widely considered to be an environmental risk factor for MS. Many studies investigating the therapeutic effects of vitamin D on MS have been applied. The objective of this systematic review and meta-analysis was to evaluate the effectiveness of vitamin D in MS patients...
May 12, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29778026/impacts-of-initial-temperature-and-cylindrical-obstacles-on-the-dispersing-flammable-limits-of-accidental-methane-releases-in-an-lng-bunkering-terminal
#9
Byung Chul Choi, Kweon-Ha Park, Deog-Hee Doh
This paper presents a numerical study on the dispersing flammable limits with respect to the initial methane releases at TCH4,0  = -50 and -150 °C in the crosswind of ambient air according to the arrangement of (a) No Tank, (b) Tank I, (c) Tank II, and (d) Tank I and II on the ground. To provide a better physical insight on the dispersion behaviors of the methane releases, the spatial distributions of the quasi-averaged methane concentration and flow fields were mainly analyzed using 3-D large eddy simulations...
May 16, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29778018/phytochemistry-and-pharmacology-of-anti-depressant-medicinal-plants-a-review
#10
REVIEW
Jeanette Martins, Brijesh S
Stress renders an individual to experience mental pressure and exhaustion which brings about feelings of anxiety, depression, anger and/or other negative emotions. Depression affects a person's state of mind, behaviour, health and is often associated with suicide. The use of anti-depressant drugs as therapeutic agents is associated with symptoms such as, delayed onset of action, side-effects, drug-drug and dietary interactions, sexual dysfunction, cardiac toxicity, etc. Thus, there is need to target these issues and improve current treatment options...
May 16, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29778014/expression-of-grape-acs1-in-tomato-decreases-ethylene-and-alters-the-balance-between-auxin-and-ethylene-during-shoot-and-root-formation
#11
Xia Ye, Mengmeng Fu, Yu Liu, Dongliang An, Xianbo Zheng, Bin Tan, Jidong Li, Jun Cheng, Wei Wang, Jiancan Feng
Ethylene plays an important role in the grape rachis, where its production can be 10 times higher than in the berry. VvACS1 is the only rachis-specific ACC synthase (ACS) gene, and its expression is coincident with ethylene production in the rachis of Vitis vinifera 'Thompson seedless'. VvACS1 was cloned and ectopically expressed in tomato (Solanum lycopersicum 'Moneymaker'). Lateral buds were increased in two- or four-week-old 35s∷VvACS1 transgenic tomato plants after transplanting. Compared with wild-type (WT) plants, the transgenic tomato plants showed higher expression of the VvACS1 gene in the flowers, leaves, rachis, and fruits...
May 4, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29778007/augmentation-of-the-expression-of-the-eotaxin-receptor-on-duodenal-neutrophils-by-il-21
#12
Yuji Takeda, Tomoyuki Kato, Nobuhito Nemoto, Akemi Araki, Mohammad Yeashin Gazi, Hidetoshi Nara, Hironobu Asao
Inflammation can occur via different mechanisms, such as via acute and chronic responses, on numerous occasions and function accordingly through various roles. There are more than five subsets of neutrophils; neutrophilic heterogeneity is modulated by the inflammatory condition. To understand the characteristics of inflammation, identification of atypical neutrophils is important. In this study, we found that the expression of eotaxin receptor (CD193) on atypical neutrophils in the duodenum is augmented in IL-21 isoform transgenic (Tg) mice...
May 16, 2018: Cytokine
https://www.readbyqxmd.com/read/29777999/targeted-delivery-of-cd44s-sirna-by-scfv-overcomes-de-novo-resistance-to-cetuximab-in-triple-negative-breast-cancer
#13
Wenyan Fu, Hefen Sun, Yang Zhao, Mengting Chen, Lipeng Yang, Xueli Yang, Wei Jin
The overexpression of EGFR often occurs in TNBC, and the anti-EGFR receptor antibody cetuximab is used widely to treat metastatic cancer in the clinic. However, EGFR-targeted therapies have been developed for TNBC without clinical success. In this study, we show that impaired EGFR degradation is crucial for resistance to cetuximab, which depends on the cell surface molecule CD44. To further investigate the role of CD44 in EGFR signaling and its treatment potential, we developed a targeting fusion protein composed of an anti-EGFR scFv generated from cetuximab and truncated protamine, called Ce-tP...
May 16, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29777993/toenail-selenium-genetic-variation-in-selenoenzymes-and-risk-and-outcome-in-glioma
#14
Noah C Peeri, Jordan H Creed, Gabriella M Anic, Reid C Thompson, Jeffrey J Olson, Renato V LaRocca, Sajeel A Chowdhary, John D Brockman, Travis A Gerke, L Burton Nabors, Kathleen M Egan
BACKGROUND: Selenium is an essential trace element obtained through diet that plays a critical role in DNA synthesis and protection from oxidative damage. Selenium intake and polymorphisms in selenoproteins have been linked to the risk of certain cancers though data for glioma are sparse. METHODS: In a case-control study of glioma, we examined the associations of selenium in toenails and genetic variants in the selenoenzyme pathway with the risk of glioma and patient survival...
May 16, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29777986/predicting-of-the-refractive-index-of-haemoglobin-using-the-hybrid-ga-svr-approach
#15
Tajudeen A Oyehan, Ibrahim O Alade, Aliyu Bagudu, Kazeem O Sulaiman, Sunday O Olatunji, Tawfik A Saleh
The optical properties of blood play crucial roles in medical diagnostics and treatment, and in the design of new medical devices. Haemoglobin is a vital constituent of the blood whose optical properties affect all of the optical properties of human blood. The refractive index of haemoglobin has been reported to strongly depend on its concentration which is a function of the physiology of biological cells. This makes the refractive index of haemoglobin an essential non-invasive bio-marker of diseases. Unfortunately, the complexity of blood tissue makes it challenging to experimentally measure the refractive index of haemoglobin...
April 30, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29777981/bare-footprint-metric-analysis-methods-for-comparison-and-identification-in-forensic-examinations-a-review-of-literature
#16
REVIEW
Richa Mukhra, Kewal Krishan, Tanuj Kanchan
Footprint is one of the most common types of physical evidence recovered at a crime scene. The forensic footprint evidence may play an important role in establishing the identity of a person; therefore, its examination is of prime importance. A link may be established by observing and comparing the morphological features of footprints with the perpetrator. These barefoot prints may be present as a two-dimensional print or a three-dimensional imprint depending on the substrate upon which they have been impressed upon and accordingly different methods and techniques are implemented in order to identify the questioned prints...
May 9, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29777978/the-buffering-role-of-the-family-in-the-relationship-between-job-loss-and-self-perceived-health-longitudinal-results-from-europe-2004-2011
#17
Giulia Tattarini, Raffaele Grotti, Stefani Scherer
Unemployment has numerous negative consequences for health, but the family and the welfare state can mitigate these consequences. How the family supports its members and whether and to what extent this interacts with the broader context is still an open question. Our evidence show that job loss is causally linked to significant declines in health for men, but not for women. Yet, the increased risk of poor health is lower for coupled men, especially if the partner is employed. This suggests that both emotional and economic support play a role...
May 16, 2018: Health & Place
https://www.readbyqxmd.com/read/29777959/extracellular-matrix-expression-in-human-pluripotent-stem-cell-derived-retinal-organoids-recapitulates-retinogenesis-in-vivo-and-reveals-an-important-role-for-impg1-and-cd44-in-the-development-of-photoreceptors-and-interphotoreceptor-matrix
#18
Majed Felemban, Birthe Dorgau, Nicola Claire Hunt, Dean Hallam, Darin Zerti, Roman Bauer, Yuchun Ding, Joseph Collin, David Steel, Natalio Krasnogor, Jumana Al-Aama, Susan Lindsay, Carla Mellough, Majlinda Lako
The extracellular matrix (ECM) plays an important role in numerous processes including cellular proliferation, differentiation, migration, maturation, adhesion guidance and axonal growth. To date, there has been no detailed analysis of the ECM distribution during retinal ontogenesis in humans and the functional importance of many ECM components is poorly understood. In this study, the expression of key ECM components in adult mouse and monkey retina, developing and adult human retina and retinal organoids derived from human pluripotent stem cells was studied...
May 16, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29777956/how-do-gender-relations-affect-the-working-lives-of-close-to-community-health-service-providers-empirical-research-a-review-and-conceptual-framework
#19
Rosalind Steege, Miriam Taegtmeyer, Rosalind McCollum, Kate Hawkins, Hermen Ormel, Maryse Kok, Sabina Rashid, Lilian Otiso, Mohsin Sidat, Kingsley Chikaphupha, Daniel Gemechu Datiko, Rukhsana Ahmed, Rachel Tolhurst, Woedem Gomez, Sally Theobald
Close-to-community (CTC) providers have been identified as a key cadre to progress universal health coverage and address inequities in health service provision due to their embedded position within communities. CTC providers both work within, and are subject to, the gender norms at community level but may also have the potential to alter them. This paper synthesises current evidence on gender and CTC providers and the services they deliver. This study uses a two-stage exploratory approach drawing upon qualitative research from the six countries (Bangladesh, Indonesia, Ethiopia, Kenya, Malawi, Mozambique) that were part of the REACHOUT consortium...
May 5, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29777955/perspectives-and-limitations-for-nucleo-t-side-analogs-in-future-hbv-therapies
#20
REVIEW
Massimo Levrero, Miroslava Subic, Francois Villeret, Fabien Zoulim
The latest generation of nucleo(t)side analogs (NAs) provide robust virus suppression with high barrier to resistance. Long term NAs treatment is associated with a partial restoration in HBV-specific T-cell functions, regression of fibrosis, no disease progression and a reduction of HCC risk but rarely lead to cure and life-long treatments is often required. New insights into the hepatitis B viral life cycle and the host immune response have expanded the potential targets for drug therapies with interesting antiviral candidates and novel immunotherapeutic approaches in early stage development...
May 16, 2018: Current Opinion in Virology
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