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https://www.readbyqxmd.com/read/29236270/endoscopic-endonasal-management-of-recurrent-maxillary-mucoceles-using-biliary-t-tube-stenting
#1
Noritsugu Ono, Shin Ito, Hirotomo Homma, Hiroko Okada, Junko Murata, Katsuhisa Ikeda
Mucoceles of the paranasal sinus can be managed endoscopically with an extremely low recurrence rate. Frontal sinus mucoceles can sometimes be prevented from closing and reforming by stenting, which to the best of our knowledge has not yet been reported in the maxillary sinus. We describe the cases of 5 patients-3 men and 2 women, aged 47 to 75 years (mean: 59.6)-with a recurrent and intractable maxillary sinus mucocele that was managed with biliary T-tube stenting. The indications for stenting included recurrent episodes of mucocele with or without a lateral location with a relatively thick bony wall...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29236226/evaluation-of-left-ventricular-diastolic-function-state-of-the-art-after-35%C3%A2-years-with-doppler-assessment
#2
REVIEW
Otto A Smiseth
Left ventricular (LV) diastolic function can be evaluated by echocardiographic indices of LV relaxation/restoring forces, diastolic compliance, and filling pressure. By using a combination of indices, diastolic function can be graded and LV filling pressure estimated with high feasibility and good accuracy. Evaluation of diastolic function is of particular importance in patients with unexplained exertional dyspnea or other symptoms or signs of heart failure which cannot be attributed to impaired LV systolic function and to assess filling pressure in patients with heart failure and reduced LV ejection fraction...
December 13, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/29236097/a-randomized-cohort-controlled-trial-to-compare-intern-sign-out-training-interventions
#3
Soo-Hoon Lee, Christopher Terndrup, Phillip H Phan, Sandra E Zaeh, Kwame Atsina, Nicole Minkove, Alexander Billioux, Souvik Chatterjee, Idoreyin Montague, Bennett Clark, Andrew Hughes, Sanjay V Desai
BACKGROUND: Although previous studies have investigated the efficacy of specific sign-out protocols (such as the illness severity, patient summary, action list, situation awareness and contingency planning, and synthesis by reviewer [I-PASS] bundle), the implementation of a bundle can be time consuming and costly. We compared 4 sign-out training pedagogies on sign-out quality. OBJECTIVE: To evaluate training interventions that best enhance multidimensional sign-out quality measured by information exchange, task accountability, and personal responsibility...
December 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29235932/retrospective-study-of-the-presentation-diagnosis-and-management-of-16-cats-with-otitis-media-not-due-to-nasopharyngeal-polyp
#4
Nicola Swales, Aiden Foster, Natalie Barnard
Objectives The aim of this study was to analyse retrospectively cats diagnosed with otitis media (OM) not due to nasopharyngeal polyp, and to review the clinical outcome with surgical and medical management. Methods Patient records were searched for cats diagnosed with OM. The diagnosis of OM was based on the presence of clinical signs, including neurological signs, respiratory signs and signs of otitis externa, and on the basis of evidence of thickened or irregular bullae walls, or the presence of fluid within the tympanic cavity; in those that had diagnostic imaging...
December 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29235746/clinical-problem-solving-a-tobacco-merchant-who-can-t-spit
#5
Sandra Benizri, Nancy Agmon-Levin, Noam D Kitrey, Dan Carter, Elinor Goshen, Yehonathan Sharabi
A 47 year old man presented with a combination of dry mouth and lightheadedness while standing. His medical background was unremarkable except for cigarette smoking and hyperlipidemia. Sjögren's syndrome was ruled out, and he was referred for evaluation of orthostatic hypotension, which by then included syncopal episodes and injuries. Additional symptoms included dry eyes, constipation, reduced sweating, and erectile dysfunction. After excluding medications and structural cardiac abnormalities as causes of orthostatic hypotension, a clinical autonomic evaluation was performed...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29235590/unravelling-the-hydrophobicity-of-urea-in-water-using-thermodiffusion-implications-for-protein-denaturation
#6
Doreen Niether, Silvia Di Lecce, Fernando Bresme, Simone Wiegand
Urea is widely used as a protein denaturant in aqueous solutions. Experimental and computer simulation studies have shown that it dissolves in water almost ideally at high concentrations, introducing little disruption in the water hydrogen bonded structure. However, at concentrations of the order of 5 M or higher, urea induces denaturation in a wide range of proteins. The origin of this behaviour is not completely understood, but it is believed to stem from a balance between urea-protein and urea-water interactions, with urea becoming possibly hydrophobic at a specific concentration range...
December 13, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29235530/tri-microspheres-prevent-key-signs-of-dry-eye-disease-in-a-murine-inflammatory-model
#7
Michelle L Ratay, Stephen C Balmert, Abhinav P Acharya, Ashlee C Greene, Thiagarajan Meyyappan, Steven R Little
Dry eye disease (DED) is a highly prevalent, ocular disorder characterized by an abnormal tear film and ocular surface. Recent experimental data has suggested that the underlying pathology of DED involves inflammation of the lacrimal functional unit (LFU), comprising the cornea, conjunctiva, lacrimal gland and interconnecting innervation. This inflammation of the LFU ultimately results in tissue deterioration and the symptoms of DED. Moreover, an increase of pathogenic lymphocyte infiltration and the secretion of pro-inflammatory cytokines are involved in the propagation of DED-associated inflammation...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29235389/extracellular-genomic-biomarkers-of-osteoarthritis
#8
Emma Budd, Giovanna Nalesso, Ali Mobasheri
Introduction Osteoarthritis (OA), a chronic, debilitating and degenerative disease of the joints, is the most common form of arthritis. The seriousness of this prevalent and chronic disease is often overlooked. Disease modifying OA drug development is hindered by the lack of soluble biomarkers to detect OA early. The objective of OA biomarker research is to identify early OA prior to the appearance of radiographic signs and the development of pain. Areas covered This review has focused on extracellular genomic material that could serve as biomarkers of OA...
December 13, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/29235240/gender-differences-in-first-self-perceived-signs-and-symptoms-in-patients-with-an-at-risk-mental-state-and-first-episode-psychosis
#9
Ulrike Heitz, Erich Studerus, Stephanie Menghini-Müller, Martina Papmeyer, Laura Egloff, Sarah Ittig, Astrid Navarra, Christina Andreou, Anita Riecher-Rössler
AIM: Gender differences in the current symptomatology of patients with psychotic disorders have previously been described in the literature. However, it has not yet been investigated whether gender differences exist in the very first self-perceived signs or symptoms of illness onset. The aim of this study was to investigate this aspect in at-risk mental state (ARMS) and first-episode psychosis (FEP) patients. METHODS: ARMS and FEP were recruited via the early detection of psychosis (FePsy) clinic Basel, Switzerland...
December 13, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29235232/signs-of-electrocochleography-on-endolymphatic-sac-decompression-for-patients-with-m%C3%A3-ni%C3%A3-re-s-disease-our-experience-in-12-patients
#10
Wei Li, Yan Lei, Jiang Zhu, Yi Qian, Guo-Ting Ma, Tao Lu, Guo-Hua Hu, Hou-Yong Kang
Endolymphatic hydrops (ELH) is a well-established histological marker of Ménière's Disease (MD). The diagnosis of MD still depends on clinical symptoms complemented with inner ear function tests. Thus far, definitive diagnosis remains difficult. It is necessary for clinicians to explore an objective examination to diagnose MD and to monitor patients' ELH. This article is protected by copyright. All rights reserved.
December 13, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29235076/a-comparison-of-the-impact-of-physical-exercise-cognitive-training-and-combined-intervention-on-spontaneous-walking-speed-in-older-adults
#11
Kristell Pothier, Christine Gagnon, Sarah A Fraser, Maxime Lussier, Laurence Desjardins-Crépeau, Nicolas Berryman, Marie-Jeanne Kergoat, T T Minh Vu, Karen Z H Li, Laurent Bosquet, Louis Bherer
BACKGROUND: Spontaneous walking speed (SWS) is one of the most important indicators of health in older adults. Studies have shown benefits of physical trainings on SWS in older adults but the impact of cognitive training and multidomain interventions remains understudied. AIMS: This original study aimed at comparing the impact of aerobic/resistance exercise, computerized cognitive training and the combination of both interventions compared with active control conditions on SWS in healthy older adults...
December 12, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29235056/separating-arterial-pressure-increases-and-decreases-in-assessing-cardiac-baroreflex-sensitivity-via-sequence-and-bivariate-phase-rectified-signal-averaging-techniques
#12
Beatrice De Maria, Vlasta Bari, Marco Ranucci, Valeria Pistuddi, Giovanni Ranuzzi, Anielle C M Takahashi, Aparecida M Catai, Laura Dalla Vecchia, Sergio Cerutti, Alberto Porta
Cardiac baroreflex (cBR) is activated by both arterial pressure (AP) increases and decreases. Sequence method, a widely utilized tool assessing cBR sensitivity (cBRS) from spontaneous heart period (HP) and systolic AP (SAP) variations, allows the separated computation of cBRS from positive and negative SAP variations. The recently proposed phase-rectified signal averaging (PRSA) method has the same feature but it has been applied so far solely to positive SAP variations. We adapted the PRSA method to compute cBRS over negative SAP variations and we compared the results with those derived from sequence method over two protocols: (i) graded head-up tilt (HUT) at 15, 30, 45, 60, and 75° in 19 healthy subjects and (ii) general anesthesia induction in 118 patients undergoing coronary artery bypass graft surgery...
December 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29234934/early-detection-of-left-ventricular-diastolic-dysfunction-using-conventional-and-speckle-tracking-echocardiography-in-a-large-animal-model-of-metabolic-dysfunction
#13
Mark M P van den Dorpel, Ilkka Heinonen, Sanne M Snelder, Hendrik J Vos, Oana Sorop, Ron T van Domburg, Daphne Merkus, Dirk J Duncker, Bas M van Dalen
Left ventricular (LV) diastolic dysfunction is one of the important mechanisms responsible for symptoms in patients with heart failure. The aim of the current study was to identify parameters that may be used to detect early signs of LV diastolic dysfunction in diabetic pigs on a high fat diet, using conventional and speckle tracking echocardiography. The study population consisted of 16 healthy Göttingen minipigs and 18 minipigs with experimentally induced metabolic dysfunction. Echocardiography measurements were performed at baseline and 3-month follow-up...
December 12, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29234860/impact-of-right-ventricular-distensibility-on-congestive-heart-failure-with-preserved-left-ventricular-ejection-fraction-in-the-elderly
#14
Daisuke Harada, Hidetsugu Aasanoi, Ryuichi Ushijima, Takahisa Noto, Junya Takagawa, Hisanari Ishise, Hiroshi Inoue
To elucidate involvement of age-related impairments of right ventricular (RV) distensibility in the elderly congestive heart failure (CHF), we examined the prevalence of less-distensible right ventricle in patients with preserved left ventricular ejection fraction (LVEF) over a wide range of ages. In 893 patients aged from 40 to 102 years, we simultaneously recorded electrocardiogram, phonocardiogram, and jugular venous pulse wave. Using signal-processing techniques, the prominent 'Y' descent of jugular pulse waveform was detected as a hemodynamic sign of a less-distensible right ventricle...
December 13, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29234663/reconstruction-with-iliac-pedestal-cup-and-proximal-femur-tumor-prosthesis-after-wide-resection-of-chondrosarcoma-10-year-follow-up-results
#15
Diogo Lino Moura, Rúben Fonseca, João Freitas, António Figueiredo, José Casanova
Chondrosarcoma is a malignant cartilage-forming neoplasm. It is difficult to treat because of resistance to both chemotherapy and radiation, making wide local excision the only treatment. This report presents an active, 43 year-old man who was diagnosed with recurrent clear cell chondrosarcoma of the proximal left femur, previously reconstructed with a total hip prosthesis, extending to the weight-bearing dome of the acetabulum. Cancer staging study revealed no signs of tumor dissemination at distance. Given the excellent functional status of the patient, the authors performed a Enneking-Dunham type periacetabular pelvic resection and resected en bloc, with the total hip prosthesis including 22 cm of the femur and a portion of the hip abductor apparatus...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29234659/accessory-muscle-of-the-flexor-digitorum-superficialis-and-its-clinical-implications
#16
Edie Benedito Caetano, João José Sabongi Neto, Lucas Augusto Ayres Ribas, Edson Vinícius Milanello
Anatomical variations of the flexor digitorum superficialis (FDS) muscle and tendon unit are frequently reported by anatomists and clinicians. Anatomical muscle variations of the FDS and its tendons may include variations of muscle belly, presence of accessory or duplicate tendons, abnormal tendon connections, and absence of muscle or tendon components. Such variations may or may not have clinical implications. This report presents a case not described previously: a unilateral accessory muscle of the flexor digitorum superficialis which was connected by a thick tendon to the flexor digitorum superficialis muscle; it was directed proximally to the insertion of the medial epicondyle of the humerus, next to the superficialis head of the pronator teres muscle...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29234603/a-retrospective-study-of-clinico-epidemiological-profile-of-snakebite-related-deaths-at-a-tertiary-care-hospital-in-midnapore-west-bengal-india
#17
Rituparna Ghosh, Koushik Mana, Kripasindhu Gantait, Sumana Sarkhel
Objective: Snakebite is one of the neglected tropical diseases that World Health Organization (WHO) aimed to eradicate. The objective of the study is to investigate the mortality and morbidity due to snakebite at Midnapore Medical College & Hospital in Paschim Medinipur district, West Bengal, India. Methods & materials: This is a record-based, retrospective, descriptive epidemiological study conducted from January 2012 to December 2016 at Midnapore Medical College and Hospital(MMCH), Paschim Medinipur district, West Bengal...
2018: Toxicology Reports
https://www.readbyqxmd.com/read/29234557/the-diagnostic-accuracy-of-the-lever-sign-for-detecting-anterior-cruciate-ligament-injury
#18
Edward P Mulligan, Amanda Anderson, Seth Watson, Robert J Dimeff
Background: An alternative physical examination procedure for evaluating the integrity of the anterior cruciate ligament (ACL) has been proposed in the literature but has not been validated in a broad population of patients with a symptomatic complaint of knee pain for its diagnostic value. Purpose: To investigate the diagnostic accuracy of the Lever Sign to detect ACL tears and compare the results to Lachman testing in both supine and prone positions. Study design: Prospective, blinded, diagnostic accuracy study...
December 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29234551/use-of-insecticide-treated-mosquito-net-among-pregnant-women-and-guardians-of-children-under-five-in-the-democratic-republic-of-the-congo
#19
Joseph N Inungu, Nestor Ankiba, Mark Minelli, Vincent Mumford, Dido Bolekela, Bienvenu Mukoso, Willy Onema, Etienne Kouton, Dolapo Raji
Background: Insecticide-treated mosquito nets (ITNs) are one of the most effective tools for preventing malaria in sub-Saharan Africa. Objective: This study examined knowledge, attitude, and practice on the use of ITNs in the prevention of malaria among pregnant women and guardians of children under five in the Democratic Republic of the Congo. Methods: A total of 5,138 pregnant women and guardians of children under five were interviewed. Results: The majority of participants (>80%) knew the signs and symptoms of malaria; 81...
2017: Malaria Research and Treatment
https://www.readbyqxmd.com/read/29234493/what-are-the-risks-of-manual-treatment-of-the-spine-a-scoping-review-for-clinicians
#20
REVIEW
Gabrielle Swait, Rob Finch
Background: Communicating to patients the risks of manual treatment to the spine is an important, but challenging element of informed consent. This scoping review aimed to characterise and summarise the available literature on risks and to describe implications for clinical practice and research. Method: A methodological framework for scoping reviews was followed. Systematic searches were conducted during June 2017. The quantity, nature and sources of literature were described...
2017: Chiropractic & Manual Therapies
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