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Alan Danielski, Michael Farrell
CASE DESCRIPTION:  An 8-month-old American Bulldog was presented for assessment of bilateral thoracic limb lameness. Computed tomographic imaging revealed large, deep osteochondritis dissecans lesions in both humeral heads. TREATMENT AND OUTCOME:  The osteochondritis dissecans lesions were debrided and the exposed subchondral defects were prepared to receive synthetic grafts. Circular implants consisting of a surface layer of polycarbonate urethane and a deep layer of lattice-type titanium were implanted into the osteochondral defects to reconstruct the articular surface topography...
June 20, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
Ray El Boustany
BACKGROUND: Diabetic nephropathy has become the most common cause of chronic kidney disease (CKD). Despite the progress accomplished in therapy, the prevalence of renal disorders remains high. Some modifiable factors driving the increase in incidence of CKD, in diabetes and other settings, might have been overlooked. Consistent evidence supports a role for vasopressin, hydration state, and urine concentration in kidney health. SUMMARY: Plasma vasopressin is elevated in diabetes, even if metabolic control is good...
2018: Annals of Nutrition & Metabolism
Sofia Enhörning, Olle Melander
BACKGROUND: Type 2 diabetes, chronic kidney disease (CKD) and its cardiovascular complications are increasing as health problems worldwide. These diseases are interrelated with overlapping occurrence and once diabetes is established, the risk of cardiorenal disease is dramatically elevated. Thus, a search for unifying modifiable risk factors is key for effective prevention. SUMMARY: Elevated fasting plasma concentration of vasopressin, measured with the marker copeptin, predicts new onset type 2 diabetes as well as renal function decline...
2018: Annals of Nutrition & Metabolism
Annette T Maruca, Desiree A Diaz, Cherrill Stockmann, Laura Gonzalez
AIM: The aim of this research was to evaluate the impact of a transgender simulation on nursing students' affirmative practice when caring for a transgender person. BACKGROUND: There is a paucity of research that assesses the attitudes of nursing students toward lesbian, gay, bisexual, and transgender (LGBT) persons and a deficit in nursing curricula regarding LGBT content. METHOD: A nonexperimental, pretest-posttest design was used to evaluate nursing students' affirmative practice when caring for a transgender patient using the Gay Affirmative Practice Scale...
July 2018: Nursing Education Perspectives
Decai Tian, Xiaodong Zhu, Rong Xue, Peng Zhao, Yuanrong Yao
History In November 2012, a previously healthy 31-year-old woman was admitted to our hospital with a 2-month history of right-sided numbness, diplopia, and intermittent nausea and dizziness. She did not have a history of fever, weight loss, headache, photophobia, seizure, or extremity weakness. Physical examination revealed left abduction limitation and right-sided hypoesthesia. Kernig and Brudzinski signs were absent, and pathergy test results were negative. Laboratory evaluation revealed normal complete and differential blood counts, normal serum chemistry, and normal immune function...
July 2018: Radiology
Åke Bernhard Vallbo
This historical review describes in the first section endeavors to develop a method to record the normal traffic of impulses in human nerves, designated microneurography. The method was developed in the Department of Clinical Neurophysiology of the Academic Hospital in Uppsala, Sweden, starting in 1965. Microneurography involves the impalement of a peripheral nerve with a tungsten needle electrode. Electrode position is adjusted by hand until activity of interest is discriminated. A similar technique had not previously been tried in animal preparations; hence the large number of successful studies based on recording afferent activity in other mammals did not offer pertinent methodological guidance...
June 20, 2018: Journal of Neurophysiology
Alzira Alves de Siqueira Carvalho, Emmanuele Lacene, Guy Brochier, Clémance Labasse, Angeline Madelaine, Vinicius Gomes da Silva, Roseli Corazzini, Konstantinos Papadopoulos, Anthony Behin, Pascal Laforêt, Tania Stojkovic, Bruno Eymard, Michel Fardeau, Norma Romero
BACKGROUND: Protein aggregate myopathies (PAM) represent a group of familial or sporadic neuromuscular conditions with marked clinical and genetic heterogeneity that occur in children and adults. Familial PAM includes myofibrillar myopathies defined by the presence of desmin-positive protein aggregates and degenerative intermyofibrillar network changes. PAM is often caused by dysfunctional genes, such as DES, PLEC 1, CRYAB, FLNC, MYOT, ZASP, BAG3, FHL1, and DNAJB6. OBJECTIVE: To retrospectively analyze genetic mutations and demographic, clinical, and morphological aspects of PAM in a French population...
June 2018: Genetic Testing and Molecular Biomarkers
Mine Araz, Derya Cayir, Bekir Ucan, Alper Dilli, Erman Çakal
OBJECTIVE: (1)To define a quantitative cutoff value for incidental pituitary Technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) uptake above which is of clinical importance and (2) to investigate possible factors affecting the intensity of uptake in pituitary adenoma. MATERIALS AND METHODS: A retrospective analysis of 55 patients with a simultaneous parathyroid single-photon emission computed tomography and pituitary magnetic resonance imaging were included...
June 20, 2018: Cancer Biotherapy & Radiopharmaceuticals
Jaroslav Klepal, Tereza Stöckelová
Drawing on fieldwork in the postsocialist Czech Republic, we explore the transformative processes of biomedicalization, both within and in relation to complementary and alternative medicine (CAM). We argue that it would be simplistic to understand evidence of these processes in CAM as a sign that CAM has fallen prey to biomedicine. Instead, we show how particular CAM practices play a groundbreaking role in shaping developments in contemporary health care. In this respect, we question the utility of the concept of biomedicalization, arguing that it reduces the transformative processes to aspects of biomedicine...
June 20, 2018: Medical Anthropology
Titiksha Srivastava, Marine Schott, Roméo Juge, Viola Krizakova, M Belmeguenai, Yves Roussigné, Anne Bernand-Mantel, Laurent Ranno, Stéfania Pizzini, Salim-Mourad Cherif, Andrei Stashkevich, Stéphane Auffret, Olivier Boulle, Gilles Gaudin, Mairbek Chshiev, Claire Baraduc, Hélène Béa
Electric field control of interfacial magnetism promises low power consuming and versatile spintronic devices. More specifically, in ultra thin heavy metal/ferromagnet/insulator heterostructures, voltage gating has been shown to locally and dynamically tune properties like perpendicular magnetic anisotropy and saturation magnetization. However its effect on the nowadays widely explored antisymmetric exchange property called interfacial Dzyaloshinskii-Moriya Interaction (DMI) has not been addressed yet. This DMI plays a fundamental role in stabilizing magnetic textures known as skyrmions envisaged for memory and logic based spintronic devices...
June 20, 2018: Nano Letters
Anil Annadi, Guanglei Cheng, Hyungwoo Lee, Jung-Woo Lee, Shicheng Lu, Anthony Tylan-Tyler, Megan Briggeman, Michelle Tomczyk, Mengchen Huang, David Pekker, Chang-Beom Eom, Patrick Irvin, Jeremy Levy
SrTiO3 -based heterointerfaces support quasi-two-dimensional (2D) electron systems that are analogous to III-V semiconductor heterostructures, but also possess superconducting, magnetic, spintronic, ferroelectric, and ferroelastic degrees of freedom. Despite these rich properties, the relatively low mobilities of 2D complex-oxide interfaces appear to preclude ballistic transport in 1D. Here we show that the 2D LaAlO3 /SrTiO3 interface can support quantized ballistic transport of electrons and (non-superconducting) electron pairs within quasi-1D structures that are created using a well-established conductive atomic-force microscope (c-AFM) lithography technique...
June 20, 2018: Nano Letters
Robin Emsley, Isaac Nuamah, Srihari Gopal, David Hough, W Wolfgang Fleischhacker
BACKGROUND: It has been proposed that relapse rates after antipsychotic discontinuation may be artificially inflated and that some of these symptom recurrences may be due to rebound or withdrawal phenomena rather than due to illness recurrence. METHODS: Post hoc analysis of data from a relapse-prevention study (conducted from March 2005 to February 2007) of paliperidone palmitate once-monthly (PP1M) versus placebo was conducted to compare the nature of operationally defined relapse events in schizophrenia patients (diagnosed by DSM-IV criteria) experiencing relapses after randomization to placebo (n = 97) with those in patients receiving maintenance PP1M treatment (n = 36)...
June 19, 2018: Journal of Clinical Psychiatry
R Allan Purdy
No abstract text is available yet for this article.
June 2018: Headache
Akiko Hanai, Hiroshi Ishiguro, Takashi Sozu, Moe Tsuda, Ikuko Yano, Takayuki Nakagawa, Satoshi Imai, Yoko Hamabe, Masakazu Toi, Hidenori Arai, Tadao Tsuboyama
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting and disabling side effect of taxane anticancer agents. We prospectively evaluated the efficacy of cryotherapy for CIPN prevention. Methods: Breast cancer patients treated weekly with paclitaxel (80 mg/m2 for one hour) wore frozen gloves and socks on the dominant side for 90 minutes, including the entire duration of drug infusion. Symptoms on the treated sides were compared with those on the untreated (nondominant) sides...
February 1, 2018: Journal of the National Cancer Institute
Sabine Ruf, Niko C Bock
Background: The aetiology of temporomandibular disorders (TMD) is controversial and post-orthodontic long-term TMD data of Class II populations are scarce. Objectives: To analyse the long-term (≥15 years) effects of Herbst-multibracket appliances (MBA) Class II treatment (Tx) on signs and symptoms of TMD. Subjects and methods: All patients (University of Giessen, Germany) who underwent Herbst-MBA Tx (end of active Tx ≥ 15 years ago), could be located and agreed to participate in a recall...
June 19, 2018: European Journal of Orthodontics
Estefanía Barrientos-Arenas, Vanessa Henao-García, Diana Marcela Giraldo, Margarita María Cardona, Silvio Urcuqui-Inchima, Jhon Carlos Castaño, Juan C Hernández
OBJECTIVES.: To assess High-Density Lipoprotein (HDL) and pro-inflammatory cytokine levels in patients with dengue classified according to the severity of the clinical presentation. MATERIALS AND METHODS.: A descriptive study was carried out with 70 individuals with dengue, classified as no alarm signs (DSSA), with signs of alarm (DCSA), and severe dengue (DG); 15 healthy donors were included as controls (CS). The serum levels of IL-1β and IL-6 were quantified through ELISA, and the HDL levels through serum by a colorimetric test...
January 2018: Revista Peruana de Medicina Experimental y Salud Pública
Ana Paula Nunes de Lima Fernandes, Jessica Naiara de Medeiros Araújo, Fabiane Rocha Botarelli, Danielly Oliveira Pitombeira, Marcos Antonio Ferreira Júnior, Allyne Fortes Vitor
PURPOSE: To analyse the concept of Dry Eye Syndrome in patients admitted to Intensive Care Units (ICU). METHOD: This is a concept analysis, according to Walker's and Avant's method, conducted using an integrative review, through search in the database. Science Direct, Scopus, Cinahl, Pubmed, Lilacs, Cochrane and Web of Science. The following keywords were used: "Keratoconjuntivite Sicca", "Risk Factors", "Dry eye Syndromes" and "Intensive Care Units"...
May 2018: Revista Brasileira de Enfermagem
Leonardo Bueno Cruvinel, João Eduardo Nicaretta, Thiago de Souza Azeredo Bastos, Luiz Fellipe Monteiro Couto, Jordana Belos Dos Santos, Dina María Beltrán Zapa, Alliny Souza de Assis Cavalcante, Breno Cayeiro Cruz, Dyego Gonçalves Lino Borges, Fernando de Almeida Borges, Vando Edésio Soares, Welber Daniel Zanetti Lopes
This study aimed to identify the frequency of occurrence of Eimeria species in Holstein (taurine dairy cattle) and Nelore (zebu beef cattle) on 12 farms in the state of Goiás, Brazil. A total of 2,601 animals were evaluated, and the cattle were divided into the following age-group categories: up to three months old, four to eight months old, nine to 16 months old and cows. Fecal samples were collected directly from the rectum of all animals. None of the cattle presented any clinical signs of eimeriosis during the survey...
June 14, 2018: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
Jing-Heng Shu, Jie Yao, Yuan-Li Zhang, Desmond Y R Chong, Zhan Liu
The aim of this study is to compare the differences in the stress distributions in the temporomandibular joints (TMJs) of the patients with facial asymmetry before and after bilateral sagittal split ramus osteotomy (BSSRO) under the symmetric occlusions using the three-dimensional (3D) finite element method.Ten facial asymmetry patients (Preoperative group, age 24.6 ± 4.8 years) and 10 asymptomatic subjects (Control group, age 26.8 ± 4.9 years) were recruited. After the patients underwent BSSRO, they were further assigned as the Postoperative group...
June 2018: Medicine (Baltimore)
Wei Li, Tong Xin, Yuxin Hu, Peng Gao, Mo Chen, Jie Zhang
RATIONALE: Pulmonary hemangioma is a rare thoracic condition that can lead to hemoptysis. Here we report a case that presented with lumen dilatation suggestive of bronchiectasis on high-resolution computed tomography (CT) and was misdiagnosed as bronchiectasis for more than 10 years. PATIENT CONCERNS: A 41-year-old female patient was admitted to the Department of Respiratory Medicine due to hemoptysis. DIAGNOSES: The patient was misdiagnosed as having bronchiectasis for more than 10 years...
June 2018: Medicine (Baltimore)
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