keyword
MENU ▼
Read by QxMD icon Read
search

ADD

keyword
https://www.readbyqxmd.com/read/29782942/effects-of-light-and-dark-phase-testing-on-the-investigation-of-behavioural-paradigms-in-mice-relevance-for-behavioural-neuroscience
#1
Juliet Richetto, Marcello Polesel, Ulrike Weber-Stadlbauer
Different timing and light phases are critical factors in behavioural neuroscience, which can greatly affect the experimental outcomes of the performed tests. Despite the fact that time of testing is one of the most common factors that varies across behavioural laboratories, knowledge about the consequences of testing time on behavioural readouts is limited. Thus, in this study we systematically assessed the effect of this factor on the readout of a variety of elementary and recurrent behavioural paradigms in C57Bl/6 mice...
May 18, 2018: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29782606/-68-ga-psma-and-11-c-choline-comparison-using-a-tri-modality-pet-ct-mri-3-0-t-system-with-a-dedicated-shuttle
#2
Omar Alonso, Gerardo Dos Santos, Margarita García Fontes, Henia Balter, Henry Engler
Background: The aim of this study was to prospectively compare the detection rate of 68 Ga-PSMA versus 11 C-Choline in men with prostate cancer with biochemical recurrence and to demonstrate the added value of a tri-modality PET/CT-MRI system. Methods: We analysed 36 patients who underwent both 11 C-Choline PET/CT and 68 Ga-PSMA PET/CT scanning within a time window of 1-2 weeks. Additionally, for the 68 Ga-PSMA scan, we used a PET/CT-MRI (3.0 T) system with a dedicated shuttle, acquiring MRI images of the pelvis...
2018: Eur J Hybrid Imaging
https://www.readbyqxmd.com/read/29782586/reflective-practices-at-the-security-council-children-and-armed-conflict-and-the-three-united-nations
#3
Ingvild Bode
The United Nations Security Council passed its first resolution on children in armed conflict in 1999, making it one of the oldest examples of Security Council engagement with a thematic mandate and leading to the creation of a dedicated working group in 2005. Existing theoretical accounts of the Security Council cannot account for the developing substance of the children and armed conflict agenda as they are macro-oriented and focus exclusively on states. I argue that Security Council decision-making on thematic mandates is a productive process whose outcomes are created by and through practices of actors across the three United Nations: member states (the first United Nations), United Nations officials (the second United Nations) and non-governmental organizations (the third United Nations)...
June 2018: European journal of international relations
https://www.readbyqxmd.com/read/29782344/weight-loss-during-atomoxetine-add-on-to-clozapine-responsive-schizophrenia
#4
Ahmed Naguy, Bibi Alamiri, Bader Khraibut
No abstract text is available yet for this article.
May 16, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29782224/efficacy-and-safety-of-dupilumab-in-glucocorticoid-dependent-severe-asthma
#5
Klaus F Rabe, Parameswaran Nair, Guy Brusselle, Jorge F Maspero, Mario Castro, Lawrence Sher, Hongjie Zhu, Jennifer D Hamilton, Brian N Swanson, Asif Khan, Jingdong Chao, Heribert Staudinger, Gianluca Pirozzi, Christian Antoni, Nikhil Amin, Marcella Ruddy, Bolanle Akinlade, Neil M H Graham, Neil Stahl, George D Yancopoulos, Ariel Teper
Background Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma while maintaining asthma control is unknown. Methods We randomly assigned 210 patients with oral glucocorticoid-treated asthma to receive add-on dupilumab (at a dose of 300 mg) or placebo every 2 weeks for 24 weeks. After a glucocorticoid dose-adjustment period before randomization, glucocorticoid doses were adjusted in a downward trend from week 4 to week 20 and then maintained at a stable dose for 4 weeks...
May 21, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29782217/dupilumab-efficacy-and-safety-in-moderate-to-severe-uncontrolled-asthma
#6
Mario Castro, Jonathan Corren, Ian D Pavord, Jorge Maspero, Sally Wenzel, Klaus F Rabe, William W Busse, Linda Ford, Lawrence Sher, J Mark FitzGerald, Constance Katelaris, Yuji Tohda, Bingzhi Zhang, Heribert Staudinger, Gianluca Pirozzi, Nikhil Amin, Marcella Ruddy, Bolanle Akinlade, Asif Khan, Jingdong Chao, Renata Martincova, Neil M H Graham, Jennifer D Hamilton, Brian N Swanson, Neil Stahl, George D Yancopoulos, Ariel Teper
Background Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma. Methods We randomly assigned 1902 patients 12 years of age or older with uncontrolled asthma in a 2:2:1:1 ratio to receive add-on subcutaneous dupilumab at a dose of 200 or 300 mg every 2 weeks or matched-volume placebos for 52 weeks. The primary end points were the annualized rate of severe asthma exacerbations and the absolute change from baseline to week 12 in the forced expiratory volume in 1 second (FEV1 ) before bronchodilator use in the overall trial population...
May 21, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29781712/me-and-you-in-caregivinghood-dyadic-resistance-resources-and-deficits-out-of-the-informal-caregiver-s-perspective
#7
Mia M T Wennerberg, Solveig M Lundgren, Monica Eriksson, Ella Danielson
OBJECTIVE: To present Specific and Generalized Resistance Resources (SRRs/GRRs) and Deficits (SRDs/GRDs) described by 32 informal caregivers as originating from themselves and their older adult carerecipients as dyads. METHOD: Salutogenic interviewing was used to assemble data from caregivers. A theory-driven, memo-guided and comparative analysis using within- and across- case analysis was applied to unravel resources and deficits influencing the outcomes when they managed tension associated with caregiving...
May 21, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29781701/intervention-for-bilingual-speech-sound-disorders-a-case-study-of-an-isixhosa-english-speaking-child
#8
Kate Rossouw, Michelle Pascoe
 Bilingualism is common in South Africa, with many children acquiring isiXhosa as a home language and learning English from a young age in nursery or crèche. IsiXhosa is a local language, part of the Bantu language family, widely spoken in the country. Aims: To describe changes in a bilingual child's speech following intervention based on a theoretically motivated and tailored intervention plan. Methods and procedures: This study describes a female isiXhosa-English bilingual child, named Gcobisa (pseudonym) (chronological age 4 years and 2 months) with a speech sound disorder...
March 19, 2018: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://www.readbyqxmd.com/read/29781685/detection-referral-and-control-of-diabetes-and-hypertension-in-the-rural-eastern-cape-province-of-south-africa-by-community-health-outreach-workers-in-the-rural-primary-healthcare-project-health-in-every-hut
#9
Angela A Morris-Paxton, Paul Rheeder, Rose-Marie G Ewing, Dillon Woods
BACKGROUND:  Non-communicable diseases, mainly cardiovascular diseases, diabetes, cancer and chronic respiratory diseases, are responsible for approximately 63% of all deaths occurring worldwide in any given year. The majority of these deaths have occurred in low- and middle-income countries (LMICs). The latest World Health Organization (WHO) report shows that the increase in diabetes is also most pronounced in the LMICs. The South African Labour and Development Research Unit estimated a 9% prevalence within the adult population in 2016...
April 11, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29781675/axial-sesamoiditis-in-the-horse-a-review
#10
Christelle Le Roux, Ann Carstens
Axial sesamoiditis or osteitis of the proximal sesamoid bones (PSBs) in the horse is described as a rare condition. The cause remains unknown and speculative, with vascular, infectious, and traumatic aetiologies implicated. It is specifically associated with injury of the palmar or plantar ligament (PL), also known as the intersesamoidean ligament. Imaging findings are generally rewarding and radiological changes are typical, if not pathognomonic, for the condition. Lesions consist of bone lysis at the apical to mid-body axial margins of the PSBs, with variable degrees of joint effusion...
March 29, 2018: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/29781661/suicide-risk-assessment-trust-an-implicit-probe-or-listen-to-the-patient
#11
Dominique P Harrison, Werner G K Stritzke, Nicolas Fay, Abdul-Rahman Hudaib
Previous research suggests implicit cognition can predict suicidal behavior. This study examined the utility of the death/suicide implicit association test (d/s-IAT) in acute and prospective assessment of suicide risk and protective factors, relative to clinician and patient estimates of future suicide risk. Patients (N = 128; 79 female; 111 Caucasian) presenting to an emergency department were recruited if they reported current suicidal ideation or had been admitted because of an acute suicide attempt. Patients completed the d/s-IAT and self-report measures assessing three death-promoting (e...
May 21, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29781528/assessing-the-competency-and-acceptability-of-community-health-worker-provision-of-standard-days-method%C3%A2-in-family-planning-services-in-gisagara-district-rwanda
#12
Lauren VanEnk, Victoria Shelus, Catherine Mugeni, Marie Mukabatsinda, Jeannette Cachan
This study assesses the competency and acceptability of community-based provision of Standard Days Method® (SDM) to first-time users in Rwanda. The national strategy equips community health workers (CHWs) to resupply pills, injectables and condoms to existing clients. With the aim of expanding access, SDM provision to first-time users was added to the method mix in Gisagara district and assessed with a 12 month prospective, mixed methods study. Thirty percent of SDM clients had never used a method of family planning and 58 percent had not been using a method for at least three months...
May 21, 2018: Studies in Family Planning
https://www.readbyqxmd.com/read/29781485/photocatalytic-difunctionalisations-of-alkenes-with-n-scn-sulfoximines
#13
Duo Zhang, Han Wang, Carsten Bolm
Reacting N-Br sulfoximines with ammonium thiocyanate leads to unprecedented sulfur reagents, which add to vinyl arenes under photocatalysis via N-centered sulfoximidoyl radicals. As a result, 1,2-difunctionalised products are obtained, which can subsequently be derivatised taking advantage of the unique properties of the thiocyanate group.
May 21, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29781446/pyro-phototronic-nanogenerator-based-on-flexible-2d-zno-graphene-heterojunction-and-its-application-in-self-powered-near-infrared-photodetector-and-active-analog-frequency-modulation
#14
Parikshit Sahatiya, Akash Shinde, Sushmee Badhulika
Even though 2D ZnO has been utilized for enhanced self-powered sensing by strain modulation due to its piezoelectric property, study on utilizing pyroelectric property of ZnO remains unexplored. The piezoelectric property of 2D ZnO works on mechanical strain which disrupts the structure of ZnO leading to the failure of device. For pyroelectric nanogenerator, temperature difference can be triggered by external light source which does not disrupt the ZnO structure and also avoids the need for physical bending/pressing as in case of piezoelectric nanogenerator...
May 21, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29781205/double-trouble-weekend-sleep-changes-are-associated-with-increased-impulsivity-among-adolescents-with-bipolar-i-disorder
#15
Anda Gershon, Sheri L Johnson, Leigh Thomas, Manpreet K Singh
OBJECTIVES: Both sleep disruption and impulsivity are important predictors of the course of bipolar disorder (BD). Although sleep disruption has been shown to intensify impulsivity, little research has considered how these two important domains interact within BD. Adolescence is a critical period for the onset of BD, and is often associated with increases in impulsivity and substantial changes in sleep. We tested the hypothesis that disruptions in sleep would increase impulsivity among adolescents, and that this effect would be more pronounced among those with BD...
May 20, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29781070/antiplatelet-therapy-for-patients-undergoing-coronary-artery-bypass-surgery
#16
Christine M DeStephan, David J Schneider
Considerable variation in the use and duration of antiplatelet medications during the perioperative and postoperative care of patients undergoing coronary artery bypass grafting (CABG) reflects limited studies focused directly on these patients as well as variation in the results reported. In this review we will highlight the incidence and mechanisms of graft closure as well as the evidence in support of antiplatelet therapy that is balanced by the impact of antiplatelet therapy on the risk of bleeding to provide recommendations for the use of antiplatelet therapy in patients undergoing CABG...
May 21, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29781024/the-owl-sensor-a-fragile-dna-nanostructure-for-the-analysis-of-single-nucleotide-variations
#17
Rebekah J Karadeema, Maria Stancescu, Tyler P Steidl, Sophia C Bertot, Dmitry M Kolpashchikov
Analysis of single nucleotide variations (SNVs) in DNA and RNA sequences is instrumental in healthcare for the detection of genetic and infectious diseases and drug-resistant pathogens. Here we took advantage of the developments in DNA nanotechnology to design a hybridization sensor, named the 'owl sensor', which produces a fluorescence signal only when it complexes with fully complementary DNA or RNA analytes. The novelty of the owl sensor operation is that the selectivity of analyte recognition is, at least in part, determined by the structural rigidity and stability of the entire DNA nanostructure rather than exclusively by the stability of the analyte-probe duplex, as is the case for conventional hybridization probes...
May 21, 2018: Nanoscale
https://www.readbyqxmd.com/read/29780767/effectiveness-of-a-multicomponent-school-based-intervention-to-reduce-bullying-among-adolescents-in-chandigarh-north-india-a-quasi-experimental-study-protocol
#18
Monica Rana, Madhu Gupta, Prahbhjot Malhi, Sandeep Grover, Manmeet Kaur
Background: Bullying perpetration and victimization is associated with significant academic, psychosocial and health related problems among adolescents. There is a need to develop effective interventions to prevent bullying among adolescents, especially in low and middle income countries. This paper presents the study protocol to develop, and evaluate the effect of multi-component school based prevention program for bullying in India. Design: Quasi-experimental study...
February 5, 2018: Journal of Public Health Research
https://www.readbyqxmd.com/read/29780648/a-case-of-adenoid-cystic-carcinoma-mimicking-a-bartholin-cyst-and-literature-review
#19
Siew Pei Goh, Brian McCully, Matthew Kyle Wagner
Adenoid cystic carcinoma of the Bartholin Gland (BG-ACC) is a rare form of vulval cancer with only approximately 350 reported cases since 1864. A review of available literature and case reports suggests an aggressive nature with protracted clinical symptoms and a tendency for local recurrence despite adequate surgical excision with or without adjuvant radiotherapy. Survival rates of 71% and 59% are reported at five and ten years. This case report endeavours to add to our body of knowledge regarding this rare disease and thus help broaden and improve our understanding of management and treatment success...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29780586/asthma-related-health-services-and-asthma-control-among-women-in-puerto-rico
#20
María Calixta Ortiz-Rivera
Objectives: This study evaluates social, behavioral, and environmental determinants to differentiate between active and inactive asthma and how predisposing, enabling, and need factors elucidate asthma-related health services and asthma control among women in Puerto Rico. Methods: This study analyzed secondary cross-sectional data from a subsample of 625 adult females who participated in the Asthma Call Back Survey in Puerto Rico. Logistic and multinomial regression analyses were conducted to examine associations between explanatory variables and asthma outcomes...
2018: SAGE Open Medicine
keyword
keyword
1170
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"