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https://www.readbyqxmd.com/read/28431001/invasive-aspergillosis-in-patients-with-underlying-liver-cirrhosis-a-prospective-cohort-study
#1
Juergen Prattes, Martin Hoenigl, Robert Krause, Walter Buzina, Thomas Valentin, Frederike Reischies, Christoph Koidl, Ines Zollner-Schwetz
The aim of this study was to determine the prevalence of invasive aspergillosis (IA) in patients with liver cirrhosis and the performance of serum galactomannan (GM) screening. Patients with decompensated liver cirrhosis and patients with compensated liver cirrhosis presenting with fever and/or respiratory symptoms were prospectively enrolled. All patients were screened by serum GM twice weekly irrespective of clinical signs and symptoms. Positive serum GM triggered work-up consisting of chest computed tomography and in case of pathological findings bronchoscopy...
April 20, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28428530/-duchenne-muscle-dystrophy-caused-bronchial-obstruction
#2
Aki Fujiwara, Nozomu Iwashiro, Masanori Ohara
Duchenne muscle dystrophy (DMD), X-linked recessive genetic disorder, causes a variety of complications including scoliosis. We report a case of bronchial obstruction and hemorrhage caused by scoliosis with DMD. A man in his forties having been hospitalized due to DMD since the age of 6, produced bloody sputum. A chest X-ray showed atelectasis in his right lower lung. A computed tomography and bronchoscopy indicated that scoliosis and thoracic deformity due to muscle dystrophy caused compression of a right main bronchus by the vertebra, leading to bronchial obstruction and bleeding...
April 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28428529/-solitary-peripheral-pulmonary-squamous-cell-papilloma-diagnostic-significance-of-18f-fluorodeoxyglucose-positron-emission-tomography-findings
#3
Tetsuya Hayashi, Syuichi Tachibana, Keiichi Nakao, Kosuke Tokitsu, Takuya Morita, Genichi Kishima
The patient was a 79-year-old woman who had received enucleation of right pulmonary papilloma 7 years earlier. She experienced bloody sputum and was therefore referred to our hospital. Chest computed tomography revealed a mass shadow(21 mm) in the right upper lobe (S2). By bronchoscopy, there was no bulging lesion in the visible range. SCC and CEA increased to 6.4 ng/ml and 6.42 ng/ml, respectively. Whole-body 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) showed increased FDG uptake in the region of the right-lung mass shadow (maximum standardized uptake value 12...
April 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28427748/post-bronchoscopy-pneumonia-in-patients-suffering-from-lung-cancer-development-and-validation-of-a-risk-prediction-score
#4
Hiroto Takiguchi, Naoki Hayama, Tsuyoshi Oguma, Kazuki Harada, Masako Sato, Yukihiro Horio, Jun Tanaka, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Takahisa Takihara, Kyoko Niimi, Tomoki Nakagawa, Ryota Masuda, Takuya Aoki, Tetsuya Urano, Masayuki Iwazaki, Koichiro Asano
BACKGROUND: The incidence, risk factors, and consequences of pneumonia after flexible bronchoscopy in patients with lung cancer have not been studied in detail. METHODS: We retrospectively analyzed the data from 237 patients with lung cancer who underwent diagnostic bronchoscopy between April 2012 and July 2013 (derivation sample) and 241 patients diagnosed between August 2013 and July 2014 (validation sample) in a tertiary referral hospital in Japan. A score predictive of post-bronchoscopy pneumonia was developed in the derivation sample and tested in the validation sample...
May 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28427542/recurrent-respiratory-papillomatosis-a-state-of-the-art-review
#5
REVIEW
Helena Ribeiro Fortes, Felipe Mussi von Ranke, Dante Luiz Escuissato, Cesar Augusto Araujo Neto, Gláucia Zanetti, Bruno Hochhegger, Carolina Althoff Souza, Edson Marchiori
Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aero-digestive tract caused by human papillomavirus (HPV) infection, which affects children and young adults. The aim of this review is to describe the main etiological, epidemiological, clinical, diagnostic, and treatment aspects of RRP. Most infections in children occur at birth, during passage through the birth canals of contaminated mothers. In adults, HPV is transmitted sexually. Papillomas usually appear as exophytic nodules, primarily in the larynx, but occasionally involving the nasopharynx, tracheobronchial tree, and pulmonary parenchyma...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28424763/airway-problems-in-neonates-a-review-of-the-current-investigation-and-management-strategies
#6
REVIEW
Quen Mok
Airway problems in the neonatal population are often life threatening and raise challenging issues in diagnosis and management. The airway problems can result from congenital or acquired lesions and can be broadly classified into those causing obstruction or those due to an abnormal "communication" in the airway. Many different investigations are now available to identify the diagnosis and quantify the severity of the problem, and these tests can be simple or invasive. Bronchography and bronchoscopy are essential to determine the extent and severity of the airway problem and to plan treatment strategy...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28419740/pulmonary-hypertension-associated-with-combined-fibrosing-mediastinitis-and-bronchial-anthracofibrosis-a-retrospective-analysis-in-a-single-chinese-hospital
#7
Yan Xu, Wenbing Xu, Yongjian Liu, Xinlun Tian, Kaifeng Xu, Juhong Shi, Mengzhao Wang, Baiqiang Cai, Min Peng
INTRODUCTION: Both fibrosing mediastinitis (FM) and bronchial anthracofibrosis (BAF) are unique diseases. The combined appearance of FM and BAF is extremely rare. OBJECTIVES: The aim of this study was to investigate the clinical features of patients with coexisting FM and BAF. METHOD: Between January 2003 and December 2015, a total of eight patients were diagnosed at the Peking Union Medical College Hospital as having combined FM and BAF. The clinical presentations, radiographic features, and bronchoscopic findings of the eight patients were reviewed...
April 17, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28416836/-comparison-between-flexible-laryngeal-mask-airway-and-reinforced-tracheal-tube-used-for-lumbar-vertebral-surgery-in-prone-position
#8
Y L Zheng, W F Song, D X Wang
OBJECTIVE: To estimate the safety and feasibility of flexible laryngeal mask airway (FLMA) for lumbar vertebral surgery in prone position. METHODS: In the study, 120 adult patients scheduled for lumbar vertebral surgery under intravenous general anesthesia were divided into group FLMA and reinforced tracheal tube (RTT) group at random. Heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded at the beginning of anesthesia induction (T0) and on the time of artificial airway intubation (T1), 1 min after intubation (T2), extubation (T3), 1 min after extubation (T4) as well...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28414675/case-report-of-sarcoidosis-as-a-great-mimicker-in-various-populations
#9
C Bowe, F Jenssen, A Espinoza
INTRODUCTION: The prevalence of sarcoidosis varies as much as 1-40 cases per 100,000 depending on region and population. Sarcoid typically occurs in people younger than 50 years old, with a peak incidence with ages between 20 and 40 years old. African Americans are 3 times more likely to develop sarcoidosis than Caucasian Americans, and woman are more likely than men to develop sarcoidosis in any ethnic group; nonetheless, it remains a valid differential across any population. CASE: A 32 year old Hispanic man presented to the Emergency Department with night sweats, fatigue, and 35 pound unintentional weight loss over the last several weeks...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28410931/a-model-of-recovery-from-inhalation-injury-and-cutaneous-burn-in-ambulatory-swine
#10
David M Burmeister, Matthew K McIntyre, Brendan Beely, Bryan Jordan, Kerfoot P Walker, James K Aden, Andriy Batchinsky, Kevin K Chung, Leopoldo C Cancio, Robert J Christy
Inhalation injury commonly accompanies thermal injury, increasing the likelihood of mortality and multiple organ dysfunction (MOD). Large animal models have given important insight into the pathophysiology of this injury; however recapitulating late MOD has remained difficult. The current report describes experiments using a smoke inhalation and burn model, with follow-up of ambulatory swine for 14days with bronchoscopy, CT scanning, and bronchoalveolar lavage fluid (BALF)/blood collection. Clinically, animals cleared airway damage in the first several days after-injury...
April 11, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28410767/non-anesthesiologist-administered-propofol-is-not-related-to-an-increase-in-transcutaneous-co2-pressure-during-flexible-bronchoscopy-compared-to-guideline-based-sedation-a-randomized-controlled-trial
#11
Roberto Mercado-Longoría, Carolina Armeaga-Azoños, Jasel Tapia-Orozco, Julio E González-Aguirre
INTRODUCTION: Evidence for the use of non-anesthesiologist-administered propofol for sedation during flexible bronchoscopy is scarce. The main objective of this study was to determine whether non-anesthesiologist-administered propofol balanced sedation was related to higher transcutaneous CO2 pressure compared with current guideline-based sedation (combination midazolam and opioid). Secondary outcomes were post-procedural recuperation time, patient satisfaction and frequency of adverse events...
April 11, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28410706/conventional-tbna-experience-over-a-10-year-period-diagnostic-yield-and-associated-limitations-in-a-tertiary-care-government-set-up
#12
Varinder Saini, Kranti Garg, Uma Handa, Ritisha Bhatt
INTRODUCTION: It is challenging for pulmonologists to sample mediastinal lymph nodes or some endobronchial lesions because of safety concerns. C-TBNA (conventional transbronchial needle aspiration) is a procedure to sample such sites, but is underutilized. We present a retrospective review of patients subjected to C-TBNA through fibre-optic bronchoscopy over a 10-year period. MATERIALS AND METHODS: Year-wise statistics of C-TBNA was reviewed and results were analyzed with regard to sampling sites and type of intraluminal lesions encountered, diagnosis made and their correlation with sampling sites, sex and age...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28410635/severe-chronic-obstructive-pulmonary-disease-is-not-associated-with-complications-after-navigational-bronchoscopy-procedures
#13
Christopher W Towe, Vanessa P Ho, Jordan Kazakov, Terence Jackson, Yaron Perry, Luis M Argote-Greene, Jennifer P Ginsberg, Philip A Linden
BACKGROUND: Electromagnetic navigational bronchoscopy (ENB) is a commonly used technique to obtain biopsies of peripheral pulmonary lesions. Little is known about risk factors for complications with this procedure. The aim of this study was to assess the complication rate associated with ENB and the relationship of complications to patient- and procedure-related factors. METHODS: Consecutive ENB procedures at an academic medical center between May 11, 2011, and September 11, 2015, were reviewed retrospectively...
April 12, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28409444/locally-invasive-thyroid-cancer-options-for-a-treatment
#14
Nicola Avenia, Jacopo Vannucci, Massimo Monacelli, Andrea Polistena, Francesco Puma
Local invasion to neighbor organs by thyroid cancer is an important prognosticator and requires different therapeutic approach. Which one is the possible best treatment option and results are evaluated in this study. A single-institution experience in thyroid cancer invading the airway is evaluated retrospectively (1990-2016). Facts regarding patients' demographics, disease history, comorbidities, condition at first evaluation and reason for referral are analyzed. Hospital records and treatment details are extracted from charts and Institutional folders...
April 13, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28409094/successful-treatment-of-azole-resistant-invasive-aspergillosis-in-a-bottlenose-dolphin-with-high-dose-posaconazole
#15
Paulien E Bunskoek, Seyedmojtaba Seyedmousavi, Steven J M Gans, Peter B J van Vierzen, Willem J G Melchers, Cornelis E van Elk, Johan W Mouton, Paul E Verweij
Invasive aspergillosis due to azole-resistant Aspergillus fumigatus is difficult to manage. We describe a case of azole-resistant invasive aspergillosis in a female bottlenose dolphin, who failed to respond to voriconazole and posaconazole therapy. As intravenous therapy was precluded, high dose posaconazole was initiated aimed at achieving trough levels exceeding 3 mg/l. Posaconazole serum levels of 3-9.5 mg/l were achieved without significant side-effects. Follow-up bronchoscopy and computed tomography showed complete resolution of the lesions...
June 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28408368/neonatal-airway-challenging-endotracheal-intubation-in-infants-with-tracheal-malformations-at-birth
#16
Arpan Agarwal, Masakazu Nakao, Victor Samuel Rajadurai, Suresh Chandran
Intubating newborn infants can be exacting. We describe two cases of endotracheal intubations in infants born with tracheal malformations. A male infant aged 30 weeks required intubation at birth for respiratory distress. Repeated attempts at intubation failed to achieve an optimal endotracheal tube position as the tube could not advance beyond the vocal cords. Hence ventilation continued with suboptimal air entry in the lungs. Bronchoscopy and CT scan confirmed tracheal stenosis. Slide tracheoplasty was successfully executed on day 78 of life...
April 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28407759/a-new-clinical-algorithm-scoring-for-management-of-suspected-foreign-body-aspiration-in-children
#17
Ibrahim A Janahi, Shabina Khan, Prem Chandra, Noora Al-Marri, Ammar Saadoon, Lolwa Al-Naimi, Maryam Al-Thani, William Greer
BACKGROUND: Foreign Body Aspiration (FBA) is a serious problem in children and delays in diagnosis and management can be devastating. The history is often vague, with subtle physical and chest radiograph abnormalities. This study aims to determine the indications for bronchoscopy in children with suspected FBA and evaluate the key clinical and statistically significant predictors of FBA, based on the patients' historical, physical and radiological findings at presentation. METHODS: This is a retrospective observational study, including patients who were admitted between January 2001 to January 2011 with suspected FBA...
April 13, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28406134/tracheobroncopathia-osteochondroplastica-three-case-reports-with-literature-review
#18
T Aktas, F Aktas, Z Ozmen, N Yaşayancan, A Arıcı
Tracheobroncopathia osteochondroplastica (TO) is a benign disease of the large airways seen very rarely. It is characterized by 1-3 mm sized ossified nodular lesions in submucosa. Its etiology is unclear, but it is stated that malignancy, chronic inflammation, amyloidosis, and genetic factors might have an effect on it. It was first described by Wilks in a 38-year-old man diagnosed with tuberculosis in 1857. Generally, patients are asymptomatic and TO is diagnosed incidentally. But symptoms become significant with infections and obstruction in tracheabronchial tree...
April 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28405997/tracheoesophageal-fistula-following-endotracheal-intubation-for-organophosphorus-poisoning
#19
Shailaja V Rao, Ajay K Boralkar, Prabhakar S Jirvankar, Mangala V Sonavani, Varsha Rotte Kaginalkar, Chimu Chinte
Tracheoesophageal fistula (TEF) is an abnormal communication between the trachea and esophagus. Iatrogenic TEF can be due to endotracheal intubation, rigid bronchoscopy or tracheostomy. Tracheostomy tube cuff volumes and pressures require constant monitoring to avoid tracheal injury. Acquired TEF which occurs after prolonged intubation, usually develops after 15-200 days of mechanical ventilation. We report a case of a large TEF secondary to endotracheal intubation for organophosphorus poison-induced respiratory failure...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28405537/vascular-air-embolism-during-bronchoscopy-procedures-incidence-pathophysiology-diagnosis-management-and-outcomes
#20
REVIEW
Venkatkiran Kanchustambham, Swetha Saladi, Kris Mehta, John Mwangi, Zafar Jamkhana, Setu Patolia
Vascular air embolism (VAE) is a rare, but potentially fatal complication of invasive medical or surgical procedures. It is a very rare complication of bronchoscopy and is most frequently reported with therapeutic bronchoscopy with Argon plasma coagulation (APC) or neodymium-doped yttrium aluminum garnet (Nd-YAG) laser. Despite being rare, as a result of its high chance of mortality and morbidity, it is imperative that physicians have high clinical suspicion to allow for early recognition and treatment. In this article, we provide a concise review of the incidence, pathophysiology, diagnosis management and outcomes of air embolism during bronchoscopy procedures...
March 9, 2017: Curēus
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