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https://www.readbyqxmd.com/read/29351111/novel-bronchoscopic-management-of-airway-bleeding-with-absorbable-gelatin-and-thrombin-slurry
#1
A Rolando Peralta, Mohit Chawla, Robert P Lee
BACKGROUND: Airway bleeding, either spontaneous or as a result of bronchoscopy, is associated with significant morbidity and mortality. Multiple bronchoscopic techniques are available to achieve complete hemostasis or as a bridge to definitive therapies. METHODS: We report our experience on the feasibility of endobronchial instillation of an absorbable gelatin and thrombin slurry (GTS) for the treatment of spontaneous hemoptysis and procedure-related bleeding. RESULTS: We identified 13 cases in which GTS was used for endobronchial hemostasis when standard bronchoscopic measures like cold saline, epinephrine, and in some cases balloon occlusion were not successful...
January 18, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29349350/a-comparison-of-the-effects-of-epinephrine-and-xylometazoline-in-decreasing-nasal-bleeding-during-nasotracheal-intubation
#2
Jaegyok Song
Background: Various techniques have been introduced to decrease complications during nasotracheal intubation. A common practice is to use nasal packing with a cotton stick and 0.01% epinephrine jelly. However, this procedure can be painful to patients and can damage the nasal mucosa. Xylometazoline spray can induce effective vasoconstriction of the nasal mucosa without direct nasal trauma. In this study, we aimed to compare the efficacy of these two methods. Methods: Patients were randomly allocated into two groups (n = 40 each): xylometazoline spray group or epinephrine packing group...
December 2017: Journal of Dental Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29349036/alternative-topical-anesthesia-for-bronchoscopy-in-a-case-of-severe-lidocaine-allergy
#3
Matthew Hensley, Benjamin H Singer
Lidocaine allergy presents a unique difficulty for both patients and providers who undergo/perform bronchoscopy. We present a case of a 73 yo male with severe lidocaine allergy who successfully underwent bronchoscopy with chloroprocaine topical anesthesia and discuss alternative topical anesthetic agents that may be used in this special situation.
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29348383/improving-diagnostic-of-pulmonary-tuberculosis-in-hiv-patients-by-bronchoscopy-a-cross-sectional-study
#4
Prayudi Santoso, Arto Y Soeroto, Rianita Juniati, Yovita Hartantri, Rudi Wisaksana, Bachti Alisjabana, Heda M Nataprawira, Ida Parwati
BACKGROUND: diagnostic of pulmonary TB in HIV patients is a problem due to non specific clinical features, or radiological appearance. HIV patients with CD4≤200 cells/mL infected with M. tuberculosis have less capacity in containing M. tuberculosis, developing granulomas, casseous necrosis, or cavities. This condition is caused by weakend inflammatory which later reduced sputum production and may cause false negative result. This study aimed to assess differences in the positivity level of acid fast bacilli (AFB) and cultures of M...
October 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29346420/initial-acquisition-and-succession-of-the-cystic-fibrosis-lung-microbiome-is-associated-with-disease-progression-in-infants-and-preschool-children
#5
Marianne S Muhlebach, Bryan T Zorn, Charles R Esther, Joseph E Hatch, Conor P Murray, Lidija Turkovic, Sarath C Ranganathan, Richard C Boucher, Stephen M Stick, Matthew C Wolfgang
The cystic fibrosis (CF) lung microbiome has been studied in children and adults; however, little is known about its relationship to early disease progression. To better understand the relationship between the lung microbiome and early respiratory disease, we characterized the lower airways microbiome using bronchoalveolar lavage (BAL) samples obtained from clinically stable CF infants and preschoolers who underwent bronchoscopy and chest computed tomography (CT). Cross-sectional samples suggested a progression of the lower airways microbiome with age, beginning with relatively sterile airways in infancy...
January 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29346253/an-innovative-solution-for-prolonged-air-leaks-the-customized-endobronchial-silicone-blocker
#6
Ravindra M Mehta, Abhinav Singla, Rajani S Bhat, Rakesh Godara, Chakravarthi Lokanath, Michael Cutaia
BACKGROUND: Prolonged air leak (PAL) is a life-threatening condition that can present either as bronchopleural fistula, or alveolar-pleural fistula (APF). Although numerous bronchoscopic treatments are described, they are either expensive, not widely available in the developing world or have limited success. We describe our experience with a novel customized endobronchial silicone blocker (CESB) for PAL treatment. METHODS: This is a retrospective study of PAL patients who underwent CESB placement...
January 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29346250/incidence-etiology-and-clinicopathologic-features-of-endobronchial-benign-lesions-a-10-year-consecutive-retrospective-study
#7
Alessandro Marchioni, Eleonora Casalini, Alessandro Andreani, Gaia Cappiello, Ivana Castaniere, Riccardo Fantini, Maria Cecilia Mengoli, Roberto Tonelli, Enrico M Clini, Giulio Rossi
BACKGROUND: Airways can be affected by non-neoplastic lesions leading to critical stenosis of the lumen. Incidence, etiology, and clinical significance of endobronchial benign lesions are not systematically characterized.This study aimed to assess the epidemiology of nonmalignant processes involving the bronchial tree on clinical, pathologic, endoscopic, and radiologic grounds. METHODS: We retrospectively analyzed bronchoscopy procedures over 10 years at the Bronchoscopy Unit of Modena University Hospital...
January 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29346249/1-versus-2-lignocaine-for-airway-anesthesia-in-flexible-bronchoscopy-without-lignocaine-nebulization-life-a-randomized-controlled-trial
#8
Karan Madan, Shiba K Biswal, Saurabh Mittal, Vijay Hadda, Anant Mohan, Gopi C Khilnani, Ravindra M Pandey, Randeep Guleria
BACKGROUND: The ideal concentration of lignocaine for topical anesthesia in bronchoscopy remains investigational. In this randomized, double blind study, we compared 1% versus 2% lignocaine for topical anesthesia. METHODS: Consecutive patients undergoing bronchoscopy were randomized to receive either 1% or 2% lignocaine solution by spray-as-you-go technique. All received 10% lignocaine spray to the oropharynx along with nasal 2% lignocaine gel. Nebulized lignocaine was not administered...
January 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29346246/comparison-of-diagnostic-potential-of-narrow-band-imaging-bronchoscopy-over-white-light-bronchoscopy-in-lung-cancer
#9
Manish Advani, Gopal Purohit, Sunil Vyas, Jyoti Kumari
BACKGROUND: Worldwide, lung cancer is the largest contributor to new cancer diagnoses and to death from cancer. Narrow band imaging (NBI) is a novel bronchoscopic technique which enables detailed examination of submucosal microcapillary grid and showed great potential in early detection of malignant lesions of the bronchial mucosa. The aim of this study was to compare diagnostic potential of NBI bronchoscopy over white light (WL) bronchoscopy in lung cancer. METHODS: We enrolled 187 patients having clinical and radiologic findings highly suspicious of lung cancer...
January 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29346245/diagnostic-yield-and-safety-of-bronchoscopist-directed-moderate-sedation-with-a-bolus-dose-administration-of-propofol-during-endobronchial-ultrasound-bronchoscopy
#10
Danai Khemasuwan, Krittika Teerapuncharoen, David C Griffin
BACKGROUND: The propofol use for moderate sedation (MS) during endobronchial ultrasound (EBUS) bronchoscopy is primarily restricted for use by an anesthesiologist because of safety concerns. The goals of this study were to demonstrate the safety and the diagnostic yield of the use of propofol by bronchoscopists and trained endoscopy nurses during EBUS bronchoscopy without intubation. METHODS: We tested a bolus propofol administration protocol targeting MS for EBUS bronchoscopy...
January 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29343149/interventional-bronchoscopy-in-adults
#11
Diana H Yu, David Feller-Kopman
The field of interventional pulmonology (IP) is a rapidly maturing subspecialty of pulmonary medicine, which emphasizes advanced diagnostic and therapeutic bronchoscopy for the evaluation and management of central airway obstruction, mediastinal/hilar adenopathy and lung nodules/masses, as well as minimally invasive diagnostic and therapeutic pleural procedures. Areas covered: This review describes advances in diagnostic and therapeutic bronchoscopic techniques. Expert Commentary: In the past decade, there has been a remarkable growth in available technology and equipment, as well as clinical and translational research efforts focused on patient-centered outcomes...
January 18, 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29343044/bronchial-blocker-positioning-learning-curve-and-confidence-in-its-use
#12
Marco Rispoli, Gianluca Zani, Federico Bizzarri, Moana R Nespoli, Dario M Mattiacci, Vanni Agnoletti, Alfonso Fiorelli, Antonio Corcione, Salvatore Buono
BACKGROUND: Despite simple and safe to use and cheap, EZ Blocker remains underused probably because it requires particular skills in recognizing airway and in using fiber- bronchoscopy to check the exact position of their cuffs. Thus, we planned an education training program on the use of EZB for novices in anaesthesia and evaluated the number of procedures required for the acquisition of the skills of this technique. METHODS: The educational training program included three different phases as follows...
January 17, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29343016/-effectiveness-and-safety-in-bronchoscopy-under-anesthesia-with-fentanyl-combined-with-midazolam
#13
Z M Luo, H Xiao, J Yuan
Objective: To study the effectiveness and safety in bronchoscopy under anesthesia with fentanyl combined with midazolam. Methods: We randomly allocated 132 patients( male 69, female 63, median age 62.9 years)requiring bronchoscopy in Beijing Xuanwu Hospital into 2 groups during January 2015 to December 2016.The trial group included 66 patients, receiving fentanyl combined with midazolam for anesthesia, while the control group of 66 patients receiving 2% lidocaine for topical anesthesia.In the trial group, there were 37 males and 29 females, with a median age of 63 years (range 26-82)...
January 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29341456/iron-pill-aspiration-cytologic-and-histologic-findings-of-a-potential-life-threatening-airway-injury-a-case-report-and-literature-review
#14
Vanessa Henriques, Diogo Costa Santos, Graça Lérias, Lucília Cáceres Monteiro
Iron pill-induced injury of bronchial mucosa is a complication following accidental aspiration of an iron tablet. Oral iron supplementation is a common therapy, particularly among advanced-age patients, who are more prone to aspiration. However, iron pill aspiration has been rarely reported in the literature, usually under the format of short case reports, with only 32 cases published in the literature. The cytologic features suspicious for this rare but potentially lethal entity have been seldom described...
January 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29340490/accuracy-of-closed-pleural-biopsy-in-the-diagnosis-of-malignant-pleural-effusion
#15
Renata Báez-Saldaña, Uriel Rumbo-Nava, Araceli Escobar-Rojas, Patricia Castillo-González, Santiago León-Dueñas, Teresa Aguirre-Pérez, María Eugenia Vázquez-Manríquez
OBJECTIVE: Previous studies have demonstrated that closed pleural biopsy (CPB) has a sensitivity of less than 60% for diagnosing malignancy. Therefore, controversy has recently emerged regarding the value of CPB as a diagnostic test. Our objective was to assess the accuracy of CPB in diagnosing malignancy in patients with pleural effusion. METHODS: This was a prospective 8-year study of individuals who underwent CPB to establish the etiology of pleural effusion...
November 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29338706/miliary-tuberculosis-with-co-existing-pulmonary-cryptococcosis-in-non-hiv-patient-without-underlying-diseases-a-case-report
#16
Toyomitsu Sawai, Takumi Nakao, Satoru Koga, Shotaro Ide, Sumako Yoshioka, Nobuko Matsuo, Hiroshi Mukae
BACKGROUND: Tuberculosis and cryptococcosis co-infection usually occurs in immunosuppressed patients with impaired cell-mediated immunity. However, there are few reports about such co-infection in non-HIV patients without underlying diseases. Here, we report a case of miliary tuberculosis with co-existing pulmonary cryptococcosis in non-HIV patient without underlying diseases. CASE PRESENTATION: An 84-year-old Asian female presented to our hospital with complaints of a 1-week history of abdominal pain and appetite loss...
January 16, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29338291/indications-for-surgical-repair-of-type-1-laryngeal-cleft
#17
Craig E Berzofsky, Tali Lando, Sandra Ettema, Jennifer Nelson, Gayle Woodson
OBJECTIVES: Type 1 laryngeal cleft (T1LC) is a congenital deficiency in the posterior glottis, resulting in a communication between the hypopharynx and glottis. No consensus treatment paradigm exists for timing and criteria for patient selection for surgical repair. Our goal is to assess whether patient characteristics can help predict improvement after surgery. METHODS: After Institutional Review Board exemption, a retrospective chart review was performed for patients undergoing surgery to diagnose a T1LC...
January 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29326491/comparison-of-midazolam-with-fentanyl-midazolam-combination-during-flexible-bronchoscopy-a-randomized-double-blind-placebo-controlled-study
#18
Amithash Marulaiah Prabhudev, Bharti Chogtu, Rahul Magazine
BACKGROUND: Sedation during flexible bronchoscopy is desirable, but the drugs and the dosage protocols that are used vary. OBJECTIVE: To study and compare the effects of midazolam with fentanyl-midazolam combination during flexible bronchoscopy. MATERIALS AND METHODS: The study was conducted on 144 patients, from October 2013 to July 2015. They answered Hospital Anxiety and Depression Scale-Anxiety subscale and a prebronchoscopy questionnaire to assess their expectation toward flexible bronchoscopy...
July 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29322720/invasive-aspergillus-pseudomembranous-and-obstructive-tracheo-bronchitis-in-an-immuno-competent-patient
#19
Ramesh S Pal, Sonam Spalgais, Amit Kumar Murar, Umesh Chandra Ojha
A 19 year female, presented with life threatening haemoptysis and cough with minimum expectoration for 3 months. Bronchoscopy showed multiple nodules in airway. The direct microscopy and culture of sputum revealed fungal elements and Aspergillus flavus respectively. Serum Galactomannan was positive. Thus diagnosis of invasive aspergillus tracheo-bronchitis made. She responded to voriconazole. Aspergillus tracheo-bronchitis is a rare form of invasive pulmonary aspergillosis in immuno-competent host. Aspergillus spp in respiratory samples should not be routinely discarded as colonization...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29321022/serum-metabolic-profiling-identified-a-distinct-metabolic-signature-in-patients-with-idiopathic-pulmonary-fibrosis-a-potential-biomarker-role-for-lysopc
#20
Barbara Rindlisbacher, Cornelia Schmid, Thomas Geiser, Cédric Bovet, Manuela Funke-Chambour
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology. Patients present loss of lung function, dyspnea and dry cough. Diagnosis requires compatible radiologic imaging and, in undetermined cases, invasive procedures such as bronchoscopy and surgical lung biopsy. The pathophysiological mechanisms of IPF are not completely understood. Lung injury with abnormal alveolar epithelial repair is thought to be a major cause for activation of profibrotic pathways in IPF...
January 10, 2018: Respiratory Research
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