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https://www.readbyqxmd.com/read/27925781/same-day-computed-tomographic-chest-imaging-for-pulmonary-nodule-targeting-with-electromagnetic-navigation-bronchoscopy-may-decrease-unnecessary-procedures
#1
Roy W Semaan, Hans J Lee, David Feller-Kopman, Andrew D Lerner, Christopher M Mallow, Jeffrey Thiboutot, Sixto A Arias, Lonny B Yarmus
RATIONALE: Bronchoscopy is commonly used for the diagnosis of suspicious pulmonary nodules discovered on computed tomographic (CT) imaging of the chest. Procedural CT imaging for bronchoscopy planning is often completed weeks to months before the date of a scheduled bronchoscopy, which may not allow discovery of a decrease in nodule size or resolution before the bronchoscopic procedure. OBJECTIVES: To determine whether same-day CT imaging of the chest discovers partial or total resolution of some lung nodules and thereby reduces unnecessary bronchoscopic procedures...
December 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27921407/trefoil-factor-family-1-is-involved-in-airway-remodeling-of-mustard-lung
#2
Mohammad Reza Nourani, Zahra Farajpour, Ali Najafi, Abbas Ali Imani Fooladi
Human airway is generally destructed by inhaled factors and is the barrier to the external environment and has a crucial role in protection of the internal homeostasis of the lung. Sulfur mustard (SM) is a chemical warfare that capable of producing severe chemical injuries primarily in the lungs. Trefoil factor family (TFFs) plays major roles in epithelial repair and homeostasis, particularly in the lung. This study attempted to verify the role of TFFs in airway that induced by sulfur mustard. Fifteen patients exposed to SM and 10 non-exposed subjects were enrolled in this study...
August 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27920001/a-case-report-of-pneumocystis-jiroveci-pneumonia-in-a-patient-with-metastatic-breast-cancer
#3
Abhijit Ray, Brian Khong, Hung T Khong
We describe a 69-year-old woman with metastatic breast cancer who developed dyspnea on exertion, persistent cough, fever and fatigue while on everolimus and exemestane combination. The initial differentials included opportunistic infection such as pneumocystis jiroveci pneumonia (PJP) vs. pneumonitis. Bronchoalveolar lavage (BAL) from bronchoscopy revealed PJP. The patient recovered after appropriate treatment. We also correlated the progressive decrease in her absolute lymphocyte count with PJP infection and recovery...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27917852/results-of-bronchoscopic-excision-in-typical-carcinoid-tumors-of-the-lung-in-turkey
#4
Hilal Boyacı, Mustafa Çörtük, Şule Gül, Elif Tanrıverdi, Mehmet Akif Özgül, Hüseyin Erhan Dinçer, Erdoğan Çetinkaya
Aim Carcinoid tumors of the lung are the tumors originating from the neuroendocrine cells. Surgical excision remains the gold standard for the treatment. Treatment with interventional bronchoscopic excision has also been reported as an alternative option in typical carcinoid tumors of the lung. The aim of this study was to present results and outcomes in patients who were bronchoscopically treated and followed-up. Methods Data of 14 patients, who had undergone bronchoscopic excision due to typical carcinoid tumor of the lung between April 2008 and July 2015 were retrospectively evaluated...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/27914752/utility-of-bronchoalveolar-lavage-for-the-diagnosis-of-asbestos-related-diseases
#5
María Jesús Cruz, Victor Curull, Lara Pijuan, Daniel Álvarez-Simón, Albert Sánchez-Font, Javier de Gracia, Mario Culebras, Jaume Ferrer
INTRODUCTION: Bronchoalveolar lavage (BAL) analysis has been proposed as an objective technique for confirming asbestos exposure. However, the reliability and diagnostic yield of this procedure has not been studied in Spain. The aim of this study was to assess the usefulness of the analysis of asbestos bodies (AB) in bronchoalveolar lavage (BAL) for the diagnosis of asbestos-related diseases (ARD). METHODS: BAL samples from 72 patients (66 male, mean age 66 years) undergoing bronchoscopy were analyzed...
November 30, 2016: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/27909284/-organizing-pneumonia-with-high-radiotracer-concentration-on-fluorodeoxyglucose-positron-emission-tomography-mimicking-pleural-dissemination-of-lung-cancer-report-of-a-case
#6
Takahisa Matsuoka, Tetsu Yamada, Shinjiro Nagai, Katsunari Matsuoka, Mitsuhiro Ueda, Yoshihiro Miyamoto
A 68-year-old man was referred to our hospital because of an abnormal shadow in the chest roentgenogram. Chest computed tomography (CT) showed the nodule in the right upper lobe (S3), 17 mm in size. One month later, fluorodeoxyglucose-positron emission tomography (FDG-PET)/CT scanning revealed positive reaction in the right upper lobe lesion and new lesion close to another lobe. In addition, interloblar small nodules were detected, 5 mm and 7 mm in size. A transbronchial brush cytology by bronchoscopy was performed, and the microscopic findings demonstrated the presence of atypical cells, suspected adenocarcinoma...
December 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27908166/improved-targeting-accuracy-of-lung-tumor-biopsies-with-scanning-beam-digital-x-ray-tomosynthesis-image-guidance
#7
Geoff Nelson, Meng Wu, Cameron Hinkel, Ganesh Krishna, Tobias Funk, Jarrett Rosenberg, Rebecca Fahrig
PURPOSE: Electromagnetic navigation bronchoscopy (ENB) provides improved targeting accuracy during transbronchial biopsies of suspicious nodules. The greatest weakness of ENB-based guidance is the registration divergence that exists between the planning CT, acquired days or weeks before the intervention, and the patient on the table on the day of the intervention. Augmenting ENB guidance with real-time tomosynthesis imaging during the intervention could mitigate the divergence and further improve the yield of ENB-guided transbronchial biopsies...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27905200/induced-sputum-to-detect-lung-pathogens-in-young-children-with-cystic-fibrosis
#8
Pamela D'Sylva, Daan Caudri, Nicole Shaw, Lidija Turkovic, Tonia Douglas, Jane Bew, Anthony D Keil, Stephen Stick, André Schultz
INTRODUCTION: Induced sputum sampling holds promise as a method for obtaining samples representative of the lower airways in young children. Collection of induced sputum samples in young children differs from older children and adults' as pharyngeal suctioning is often required. Our aim was to determine the sensitivity and specificity of induced sputum with and without airway clearance techniques to detect lower airway pathogens in children less than age 7 with cystic fibrosis. METHODS: Microbiological culture results were compared between 61 paired induced sputum and bronchoalveolar lavage fluid samples from young children with cystic fibrosis...
November 30, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27904517/the-impact-of-ace-gene-polymorphism-on-the-incidence-and-phenotype-of-sarcoidosis-in-rural-and-urban-settings
#9
Robert Kieszko, Paweł Krawczyk, Tomasz Powrózek, Aneta Szudy-Szczyrek, Michał Szczyrek, Iwona Homa, Jadwiga Daniluk, Janusz Milanowski
INTRODUCTION: Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Current theory on the etiology of this disease involves participation of genetic factors and unknown antigens present in the patients' environment. The aim of the study was to evaluate the prevalence of different polymorphic forms of the ACE gene in healthy individuals and sarcoidosis patients, and to estimate the risk of sarcoidosis in carriers of different ACE genotypes living in rural and urban settings...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27900022/conversion-of-aspergilloma-to-chronic-necrotizing-pulmonary-aspergillosis-following-treatment-with-sunitinib-a-case-report
#10
Yeon Wook Kim, Hyun Woo Lee, Jaeyoung Cho, Han-Sol Choi, Jungsil Lee, Sung Soo Park, Eun Young Heo, Kwang Nam Jin, Deog Kyeom Kim
Semi-invasive or invasive aspergillosis occurring following chemotherapy with sunitinib is a rare condition with unknown incidence and prognosis. Here, we report a case involving a 59-year-old male who had a history of underlying stable aspergilloma and was newly diagnosed with metastatic renal cell carcinoma. Following surgical resection for renal cell carcinoma and adjuvant chemotherapy with sunitinib for 8 months, the patient presented with hemoptysis. Chest computed tomography revealed an increased soft tissue mass and air crescent sign of the underlying aspergilloma, combined with consolidation and bronchial artery hypertrophy around the lesion...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27899541/subinterlobular-pleural-location-is-a-risk-factor-for-pneumothorax-after-bronchoscopy
#11
Haruka Chino, Motoyasu Iikura, Nayuta Saito, Nahoko Sato, Manabu Suzuki, Satoru Ishii, Eriko Morino, Go Naka, Jin Takasaki, Shinyu Izumi, Masayuki Hojo, Yuichiro Takeda, Haruhito Sugiyama
BACKGROUND: Pneumothorax is one of the most important complications after bronchoscopy. This study was conducted to determine the risk factors for post-bronchoscopy pneumothorax. METHODS: We retrospectively reviewed the medical records of 23 consecutive subjects who were diagnosed with iatrogenic pneumothorax after bronchoscopy between August 2010 and February 2014. Forty-six control subjects who did not develop pneumothorax after bronchoscopy were randomly selected...
December 2016: Respiratory Care
https://www.readbyqxmd.com/read/27898728/relationships-between-mucosal-antibodies-non-typeable-haemophilus-influenzae-nthi-infection-and-airway-inflammation-in-copd
#12
Karl J Staples, Stephen Taylor, Steve Thomas, Stephanie Leung, Karen Cox, Thierry G Pascal, Kristoffer Ostridge, Lindsay Welch, Andrew C Tuck, Stuart C Clarke, Andrew Gorringe, Tom M A Wilkinson
Non-typeable Haemophilus influenzae (NTHi) is a key pathogen in COPD, being associated with airway inflammation and risk of exacerbation. Why some patients are susceptible to colonisation is not understood. We hypothesised that this susceptibility may be due to a deficiency in mucosal humoral immunity. The aim of our study (NCT01701869) was to quantify the amount and specificity of antibodies against NTHi in the lungs and the associated risk of infection and inflammation in health and COPD. Phlebotomy, sputum induction and bronchoscopy were performed on 24 mild-to-moderate COPD patients and 8 age and smoking-matched controls...
2016: PloS One
https://www.readbyqxmd.com/read/27896423/long-term-outcomes-following%C3%A2-h-type-tracheoesophageal-fistula%C3%A2-repair-in-infants
#13
Augusto Zani, Luai Jamal, Giovanni Cobellis, Justyna M Wolinska, Samuel Fung, Evan J Propst, Priscilla P L Chiu, Agostino Pierro
PURPOSE: To evaluate outcomes following repair of H-type tracheoesophageal fistula (TEF). METHODS: Retrospective chart review of infants with H-type TEF treated at our institution between 2000 and 2014. Patient demographics, surgical management, and postoperative function were evaluated. RESULTS: Of the 268 patients with esophageal atresia/TEF treated at our center, 16 (6%) had an H-type TEF (10 males). Thirteen (81%) had associated anomalies...
November 28, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27896063/necrotizing-tracheobronchitis-associated-with-rheumatoid-arthritis
#14
Shigehisa Kajikawa, Kazushi Noda, Yasuhiro Nozaki
We report a case of necrotizing tracheobronchitis with rheumatoid arthritis. A 64 year-old-man presented with dry cough and was initially diagnosed with community-acquired pneumonia. The patient was admitted; he received initial antibiotic treatment. The treatment was effective and the symptoms worsened. Bronchoscopy was performed for more thorough examination. It showed that white and soft tissues were on the trachea-bronchus. Transbronchial biopsy of the tracheal lesions revealed necrotic tissue with squamous metaplasia and inflammatory cells...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27896060/diffuse-bronchiectasis-as-the-primary-manifestation-of-endobronchial-sarcoidosis
#15
Paul D Hiles, Kenneth R Kemp, Jean M Coviello
Sarcoidosis is an idiopathic disease that most commonly involves the lungs and is characterized by granulomatous inflammation. Bronchiectasis is one pulmonary manifestation of sarcoidosis, although it is almost always observed as traction bronchiectasis in the setting of fibrotic lung disease. A 50-year-old woman was evaluated for chronic cough and bronchiectasis with a small amount of peripheral upper lobe honeycombing and no significant pulmonary fibrosis or lymphadenopathy. After an extensive laboratory and imaging evaluation did not identify a cause of her bronchiectasis, bronchoscopy was performed to assess for primary ciliary dyskinesia and revealed a diffuse cobblestone appearance of the airway mucosa...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27895950/endobronchial-carcinoid-and-concurrent-carcinoid-syndrome-in-an-adolescent-female
#16
Jonathan D Cogen, Jonathan Swanson, Thida Ong
Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever. Diagnosis is frequently made by imaging and direct visualization with flexible bronchoscopy; surgery remains the gold standard treatment, and lung-sparing resections should be performed whenever possible. Though carcinoid syndrome-characterized by flushing, palpitations, wheezing, shortness of breath, and diarrhea-has been found in association with adult bronchial carcinoid tumors, to our knowledge only one previous study has reported the presence of carcinoid syndrome in a pediatric patient with an endobronchial carcinoid...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27894283/small-lung-lesions-invisible-under-fluoroscopy-are-located-accurately-by-three-dimensional-localization-technique-on-chest-wall-surface-and-performed-bronchoscopy-procedures-to-increase-diagnostic-yields
#17
Chaosheng Deng, Xiaoming Cao, Dawen Wu, Haibo Ding, Ruixiong You, Qunlin Chen, Linying Chen, Xin Zhang, Qiaoxian Zhang, Yongquan Wu
BACKGROUND: Nowadays, small peripheral pulmonary lesions (PPLs) are frequently detected and the prognosis of lung cancer depends on the early diagnosis. Because of the high fee and requiring specialized training, many advanced techniques are not available in many developing countries and rural districts. METHODS: Three sets of opaque soft copper wires visible under the fluoroscopy (Flu) in the Flu-flexible bronchoscopy (FB) group (n = 24), which determined the three planes of the lesion, were respectively placed firmly on the surface of the chest wall with adhesive tape on the chest wall...
November 29, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27891001/rigid-bronchoscopic-management-of-acute-respiratory-failure-in-a-30-year-old-woman
#18
Karan Madan, Ashesh Dhungana, Neha Kawatra Madan, Anant Mohan, Vijay Hadda, Rakesh Garg, Deepali Jain, Randeep Guleria
A 30-year-old woman presented with a history of progressive shortness of breath, cough, and hoarseness. Stridor was audible on examination. Chest X-ray showed normal lung fields and contrast-enhanced computed tomography thorax showed lower tracheal occlusion with endoluminal growth. Diagnostic flexible bronchoscopy demonstrated multiple whitish glistening nodules over both vocal cords and lower tracheal occlusion by whitish nodular growth. In view of critical central airway obstruction, rigid bronchoscopy and excision of the lower tracheal growth were performed...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27890997/complete-subglottic-tracheal-stenosis-managed-with-rigid-bronchoscopy-and-t-tube-placement
#19
Kuruswamy Thurai Prasad, Sahajal Dhooria, Inderpaul Singh Sehgal, Ashutosh Nath Aggarwal, Ritesh Agarwal
Surgery is the preferred treatment modality for benign tracheal stenosis. Interventional bronchoscopy is used as a bridge to surgery or in instances when surgery is not feasible or has failed. Stenosis in the subglottic trachea is particularly a treatment challenge, in view of its proximity to the vocal cords. Herein, we describe a patient with complete tracheal stenosis in the subglottic region, which developed after prolonged intubation and mechanical ventilation. The patient developed recurrent stenosis despite multiple surgical and endoscopic procedures...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27888824/clinico-radiological-parameters-predicting-early-diagnosis-of-foreign-body-aspiration-in-children
#20
Pradipta Kumar Parida, Nirmal Shanmugasundaram, Surianarayanan Gopalakrishnan
OBJECTIVES: This study aims to investigate clinical and radiological findings to make early diagnosis of foreign body (FB) aspiration in children. PATIENTS AND METHODS: This prospective study was conducted on 45 children younger than 12 years with a clinical diagnosis of FB aspiration undergone rigid bronchoscopy between September 2010 and May 2014. The results of 37 children (22 males, 15 females; mean age 2.6 years; range 1 to 12 years) with positive for FB on bronchoscopy were analyzed...
September 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
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