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https://www.readbyqxmd.com/read/28318790/wood-burning-pollution-in-southern-chile-pm2-5-source-apportionment-using-cmb-and-molecular-markers
#1
Ana M Villalobos, Francisco Barraza, Héctor Jorquera, James J Schauer
Temuco is a mid-size city representative of severe wood smoke pollution in southern Chile; i.e., ambient 24-h PM2.5 concentrations have exceeded 150 μg/m(3) in the winter season and the top concentration reached 372 μg/m(3) in 2010. Annual mean concentrations have decreased but are still above 30 μg/m(3). For the very first time, a molecular marker source apportionment of ambient organic carbon (OC) and PM2.5 was conducted in Temuco. Primary resolved sources for PM2.5 were wood smoke (37.5%), coal combustion (4...
March 16, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28318355/dementia-incidence-and-predictors-in-cerebral-amyloid-angiopathy-patients-without-intracerebral-hemorrhage
#2
Li Xiong, Gregoire Boulouis, Andreas Charidimou, Duangnapa Roongpiboonsopit, Michael J Jessel, Marco Pasi, Yael D Reijmer, Panagiotis Fotiadis, Alison Ayres, Emily Merrill, Kristin Schwab, Deborah Blacker, M Edip Gurol, Steven M Greenberg, Anand Viswanathan
Cerebral amyloid angiopathy (CAA) is a common cause of cognitive impairment in older individuals. This study aimed to investigate predictors of dementia in CAA patients without intracerebral hemorrhage (ICH). A total of 158 non-demented patients from the Stroke Service or the Memory Clinic who met the modified Boston Criteria for probable CAA were included. At baseline, neuroimaging markers, including lobar microbleeds (cerebral microbleeds (CMBs)), white matter hyperintensities (WMH), cortical superficial siderosis (cSS), magnetic resonance imaging (MRI)-visible centrum semiovale perivascular spaces (CSO-PVS), lacunes, and medial temporal atrophy (MTA) were assessed...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28303922/correlation-of-cerebral-microbleed-distribution-to-amyloid-burden-in-patients-with-primary-intracerebral-hemorrhage
#3
Hsin-Hsi Tsai, Li-Kai Tsai, Ya-Fang Chen, Sung-Chun Tang, Bo-Ching Lee, Ruoh-Fang Yen, Jiann-Shing Jeng
The underlying pathology of cerebral microbleeds (CMBs) with mixed lobar and deep distribution remains contentious. The aim of this study was to correlate CMBs distribution to β-amyloid burden in patients with primary intracerebral hemorrhage (ICH). Fourty-seven ICH patients underwent magnetic resonance susceptibility-weighted imaging and (11)C-Pittsburgh Compound B positron emission tomography. The amyloid burden was expressed as standardized uptake value ratio with reference to cerebellum, and presented as median (interquartile range)...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28297352/improved-setup-and-positioning-accuracy-using-a-three-point-customized-cushion-mask-bite-block-immobilization-system-for-stereotactic-reirradiation-of-head-and-neck-cancer
#4
He Wang, Congjun Wang, Samuel Tung, Andrew Wilson Dimmitt, Pei Fong Wong, Mark A Edson, Adam S Garden, David I Rosenthal, Clifton D Fuller, Gary B Gunn, Vinita Takiar, Xin A Wang, Dershan Luo, James N Yang, Jennifer Wong, Jack Phan
The purpose of this study was to investigate the setup and positioning uncertainty of a custom cushion/mask/bite-block (CMB) immobilization system and determine PTV margin for image-guided head and neck stereotactic ablative radiotherapy (HN-SABR). We analyzed 105 treatment sessions among 21 patients treated with HN-SABR for recurrent head and neck cancers using a custom CMB immobilization system. Initial patient setup was performed using the ExacTrac infrared (IR) tracking system and initial setup errors were based on comparison of ExacTrac IR tracking system to corrected online ExacTrac X-rays images registered to treatment plans...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28276199/new-insights-into-a-hot-environment-for-early-life
#5
REVIEW
Jianghong Dai
Investigating the physical-chemical setting of early life is a challenging task. In this contribution, I attempt to introduce a provocative concept from cosmology-cosmic microwave background (CMB), which is the residual thermal radiation from a hot early Universe-to the field. For this purpose, I revisit a recently deduced biomarker, the 1,6-anhydro bond of sugars in bacteria. In vitro, the 1,6-anhydro bond of sugars reflects and captures residual thermal radiation in thermochemical processes and therefore is somewhat analogous to CMB...
March 9, 2017: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/28263851/the-effects-of-different-exercise-training-modalities-on-plasma-proenkephalin-peptide-f-in-women
#6
William H DuPont, William J Kraemer, Bradley C Nindl, Elaine C Lee, Maren S Fragala, Disa L Hatfield, Lydia K Caldwell, Emily M Post, Matthew K Beeler, Jeff S Volek, Carl M Maresh
Due to the important interactions of proenkephalin fragments (e.g., proenkephalin [107-140] Peptide F) to enhance activation of immune cells and potentially combat pain associated with exercise-induced muscle tissue damage, we examined the differential plasma responses of Peptide F to different exercise training programs. Participants were tested pre-training (T1), and after 8 weeks (T2) of training. Fifty-nine healthy women were matched and then randomly assigned to one of four groups: heavy resistance strength training (STR, n=18), high intensity endurance training (END, n=14), combined strength and endurance training (CMB, n=17), or control (CON, n=10)...
March 2, 2017: Peptides
https://www.readbyqxmd.com/read/28255125/-meta-analysis-for-the-relationship-between-lipoprotein-associated-phospholipase-a2-and-ischemic-stroke
#7
Wencui Xia, Zhongyang Hu, Zhi Song
To analyze the relationship between lipoprotein-associated phospholipase A2 (Lp-PLA2) and ischemic stroke.
 Methods: Corresponding data, with case-control studies or cohorts regarding Lp-PLA2 and ischemic stroke, were retrieved from PubMed, Web of Science, Embase, the Cochrane Library, Chinese Biomedical Literature (CMB), VIP, China National Knowledge Infrastructure (CNKI), and Wanfang Database. Meta-analysis was performed by using Stata12.0.
 Results: Eight studies including 46 034 participants met the inclusion criteria...
February 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28249488/a-cmos-application-specified-integrated-circuit-for-40-ghz-high-electron-mobility-transistors-automatic-biasing
#8
M De Matteis, M De Blasi, E A Vallicelli, M Zannoni, M Gervasi, A Bau, A Passerini, A Baschirotto
This paper presents the design and the experimental results of a CMOS Automatic Control System (ACS) for the biasing of High-Electron-Mobility-Transistors (HEMT). The ACS is the first low-power mixed-signal Application-Specified-Integrated-Circuit (ASIC) able to automatically set and regulate the operating point of an off-chip 6 HEMT Low-Noise-Amplifiers (LNAs), hence it composes a two-chip system (the ACS+LNAs) to be used in the Large Scale Polarization Explorer (LSPE) stratospheric balloon for Cosmic Microwave Background (CMB) signal observation...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28228568/mri-visible-perivascular-spaces-in-cerebral-amyloid-angiopathy-and-hypertensive-arteriopathy
#9
Andreas Charidimou, Gregoire Boulouis, Marco Pasi, Eitan Auriel, Ellis S van Etten, Kellen Haley, Alison Ayres, Kristin M Schwab, Sergi Martinez-Ramirez, Joshua N Goldstein, Jonathan Rosand, Anand Viswanathan, Steven M Greenberg, M Edip Gurol
OBJECTIVE: To assess MRI-visible enlarged perivascular spaces (EPVS) burden and different topographical patterns (in the centrum semiovale [CSO] and basal ganglia [BG]) in 2 common microangiopathies: cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA). METHODS: Consecutive patients with spontaneous intracerebral hemorrhage (ICH) from a prospective MRI cohort were included. Small vessel disease MRI markers, including cerebral microbleeds (CMBs), cortical superficial siderosis (cSS), and white matter hyperintensities (WMH), were rated...
February 22, 2017: Neurology
https://www.readbyqxmd.com/read/28207801/kidney-dysfunction-and-cerebral-microbleeds-in-neurologically-healthy-adults
#10
Sang Hyuck Kim, Dong Wook Shin, Jae Moon Yun, Ji Eun Lee, Jae-Sung Lim, Be Long Cho, Hyung-Min Kwon, Jin-Ho Park
INTRODUCTION: Cerebral microbleed (CMB) is a potent risk factor for overt cerebrovascular disease. Although some studies indicated the possible role of renal dysfunction as a risk factor of CMB, the findings could not be generalized. This study aimed to investigate the association between renal dysfunction and cerebral microbleed (CMB) in neurologically healthy adults. MATERIALS AND METHODS: A total of 2,518 subjects who underwent brain MRI as part of health screening were involved in the study...
2017: PloS One
https://www.readbyqxmd.com/read/28166727/whole-genome-sequencing-of-a-plasmodium-vivax-clinical-isolate-exhibits-geographical-characteristics-and-high-genetic-variation-in-china-myanmar-border-area
#11
Shen-Bo Chen, Yue Wang, Kokouvi Kassegne, Bin Xu, Hai-Mo Shen, Jun-Hu Chen
BACKGROUND: Currently in China, the trend of Plasmodium vivax cases imported from Southeast Asia was increased especially in the China-Myanmar border area. Driven by the increase in P. vivax cases and stronger need for vaccine and drug development, several P. vivax isolates genome sequencing projects are underway. However, little is known about the genetic variability in this area until now. RESULTS: The sequencing of the first P. vivax isolate from China-Myanmar border area (CMB-1) generated 120 million paired-end reads...
February 6, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28161268/source-apportionment-and-a-novel-approach-of-estimating-regional-contributions-to-ambient-pm2-5-in-haikou-china
#12
Baoshuang Liu, Tingkun Li, Jiamei Yang, Jianhui Wu, Jiao Wang, Jixin Gao, Xiaohui Bi, Yinchang Feng, Yufen Zhang, Haihang Yang
A novel approach was developed to estimate regional contributions to ambient PM2.5 in Haikou, China. In this paper, the investigation was divided into two main steps. The first step: analysing the characteristics of the chemical compositions of ambient PM2.5, as well as the source profiles, and then conducting source apportionments by using the CMB and CMB-Iteration models. The second step: the development of estimation approaches for regional contributions in terms of local features of Haikou and the results of source apportionment, and estimating regional contributions to ambient PM2...
April 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28157096/only-white-matter-hyperintensities-predicts-post-stroke-cognitive-performances-among-cerebral-small-vessel-disease-markers-results-from-the-tabasco-study
#13
Jeremy Molad, Efrat Kliper, Amos D Korczyn, Einor Ben Assayag, Dafna Ben Bashat, Shani Shenhar-Tsarfaty, Orna Aizenstein, Ludmila Shopin, Natan M Bornstein, Eitan Auriel
BACKGROUND: White matter hyperintensities (WMH) were shown to predict cognitive decline following stroke or transient ischemic attack (TIA). However, WMH are only one among other radiological markers of cerebral small vessel disease (SVD). OBJECTIVE: The aim of this study was to determine whether adding other SVD markers to WMH improves prediction of post-stroke cognitive performances. METHODS: Consecutive first-ever stroke or TIA patients (n = 266) from the Tel Aviv Acute Brain Stroke Cohort (TABASCO) study were enrolled...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28145796/identification-of-neurovascular-changes-associated-with-cerebral-amyloid-angiopathy-from-subject-specific-hemodynamic-response-functions
#14
Rebecca J Williams, Bradley G Goodyear, Stefano Peca, Cheryl R McCreary, Richard Frayne, Eric E Smith, G Bruce Pike
Cerebral amyloid angiopathy (CAA) is a small-vessel disease preferentially affecting posterior brain regions. Recent evidence has demonstrated the efficacy of functional MRI in detecting CAA-related neurovascular injury, however, it is unknown whether such perturbations are associated with changes in the hemodynamic response function (HRF). Here we estimated HRFs from two different brain regions from block design activation data, in light of recent findings demonstrating how block designs can accurately reflect HRF parameter estimates while maximizing signal detection...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28143923/cerebral-microbleeds-as-predictors-of-mortality-the-framingham-heart-study
#15
José R Romero, Sarah R Preis, Alexa Beiser, Jayandra J Himali, Ashkan Shoamanesh, Philip A Wolf, Carlos S Kase, Ramachandran S Vasan, Charles DeCarli, Sudha Seshadri
BACKGROUND AND PURPOSE: Cerebral microbleeds (CMB) represent a common magnetic resonance imaging marker of cerebral small vessel disease, increasingly recognized as a subclinical marker of stroke and dementia risk. CMB detection may reflect the cumulative effect of vascular risk burden and be a marker of higher mortality. We investigated the relation of CMB to risk of death in community dwelling participants free of stroke and dementia. METHODS: We evaluated 1963 Framingham Original and Offspring Cohort participants (mean age 67 years; 54% women) with available brain magnetic resonance imaging and mortality data...
March 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28130469/small-vessel-disease-burden-in-cerebral-amyloid-angiopathy-without-symptomatic-hemorrhage
#16
Gregoire Boulouis, Andreas Charidimou, Michael J Jessel, Li Xiong, Duangnapa Roongpiboonsopit, Panagiotis Fotiadis, Marco Pasi, Alison Ayres, M Emily Merrill, Kristin M Schwab, Jonathan Rosand, M Edip Gurol, Steven M Greenberg, Anand Viswanathan
OBJECTIVE: Cerebral amyloid angiopathy (CAA) is a common age-related small vessel disease (SVD). Patients without intracerebral hemorrhage (ICH) typically present with transient focal neurologic episodes (TFNEs) or cognitive symptoms. We sought to determine if SVD lesion burden differed between patients with CAA first presenting with TFNEs vs cognitive symptoms. METHODS: A total of 647 patients presenting either to a stroke department (n = 205) or an outpatient memory clinic (n = 442) were screened for eligibility...
February 28, 2017: Neurology
https://www.readbyqxmd.com/read/28129602/titanium-alloy-modified-with-anti-biofouling-zwitterionic-polymer-to-facilitate-formation-of-bio-mineral-layer
#17
Miku Nishida, Tadashi Nakaji-Hirabayashi, Hiromi Kitano, Yoshiyuki Saruwatari, Kazuyoshi Matsuoka
The surface of a titanium (Ti) alloy was modified with a self-assembled monolayer of poly(ethylene glycol) methacrylate phosphate (Phosmer PE). A zwitterionic monomer (carboxymethyl betaine, CMB) could be copolymerized with the surface-bound Phosmer PE due to a flexible linker between the Ti alloy surface and a methacryloyl group of Phosmer PE. The poly(CMB) (PCMB)-modified Ti alloy plate exhibited strong suppression of protein adsorption and cell adhesion, and induced approximately twice the amount of calcium (Ca(2+)) deposition as compared to the unmodified Ti alloy plate...
April 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28107655/discrimination-between-naphthacene-and-triphenylene-using-cellulose-tris-4-methylbenzoate-and-cellulose-tribenzoate-a-computational-study
#18
Yusuke Murakami, Tohru Shibata, Kazuyoshi Ueda
The mechanisms of naphthacene and triphenylene discrimination using commercially available cellulose tris(4-methylbenzoate) (CMB) and cellulose tribenzoate (CB) chiral stationary phases were investigated using molecular mechanics calculations. Naphthacene and triphenylene could be separated by liquid chromatography on CMB and CB, with triphenylene being eluted earlier than naphthacene on both phases. However, the corresponding separation factor is much larger for CMB than for CB. The docking of these polycyclic aromatic hydrocarbons to the above polymers suggested that the most important sites of CMB and CB for interacting with these hydrocarbons are located at equivalent positions, featuring a space surrounded by main chain glucose units and benzoyl side chains...
February 1, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28088807/posterior-versus-anterior-circulation-stroke-in-young-adults-a-comparative-study-of-stroke-aetiologies-and-risk-factors-in-stroke-among-young-fabry-patients-sifap1
#19
Bettina von Sarnowski, Ulf Schminke, Ulrike Grittner, Christian Tanislav, Tobias Böttcher, Michael G Hennerici, Turgut Tatlisumak, Jukka Putaala, Manfred Kaps, Franz Fazekas, Christian Enzinger, Arndt Rolfs, Christof Kessler
BACKGROUND: Although 20-30% of all strokes occur in the posterior circulation, few studies have explored the characteristics of patients with strokes in the posterior compared to the anterior circulation so far. Especially data on young patients is missing. METHODS: In this secondary analysis of data of the prospective multi-centre European sifap1 study that investigated stroke and transient ischemic attack (TIA) patients aged 18-55 years, we compared vascular risk factors, stroke aetiology, presence of white matter hyperintensities (WMH) and cerebral microbleeds (CMB) between patients with ischaemic posterior circulation stroke (PCS) and those having suffered from anterior circulation stroke (ACS) based on cerebral MRI...
January 14, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28076478/liver-transplantation-for-carcinoma-hepatocellular-in-s%C3%A3-o-paulo-414-cases-by-the-milan-brazil-criteria
#20
COMPARATIVE STUDY
Gustavo Pilotto D Sá, Fernando P P Vicentine, Alcides A Salzedas-Netto, Carla Adriana Loureiro de Matos, Luiz R Romero, Dario F P Tejada, Paulo Celso Bosco Massarollo, Gaspar J Lopes-Filho, Adriano M Gonzalez
Background: The criterion of Milan (CM) has been used as standard for indication of liver transplantation (LTx) for hepatocellular carcinoma (HCC) worldwide for nearly 20 years. Several centers have adopted criteria expanded in order to increase the number of patients eligible to liver transplantation, while maintaining good survival rates. In Brazil, since 2006, the criterion of Milan/Brazil (CMB), which disregards nodules <2 cm, is adopted, including patients with a higher number of small nodules...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
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