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perinatal deaths information

Jens Henrichs, Viki Verfaille, Laura Viester, Myrte Westerneng, Bert Molewijk, Arie Franx, Henriette van der Horst, Judith E Bosmans, Ank de Jonge, Petra Jellema
BACKGROUND: Intrauterine growth retardation (IUGR) is a major risk factor for perinatal mortality and morbidity. Thus, there is a compelling need to introduce sensitive measures to detect IUGR fetuses. Routine third trimester ultrasonography is increasingly used to detect IUGR. However, we lack evidence for its clinical effectiveness and cost-effectiveness and information on ethical considerations of additional third trimester ultrasonography. This nationwide stepped wedge cluster-randomized trial examines the (cost-)effectiveness of routine third trimester ultrasonography in reducing severe adverse perinatal outcome through subsequent protocolized management...
October 13, 2016: BMC Pregnancy and Childbirth
Sarah Meaney, Paul Corcoran, Keelin O'Donoghue
BACKGROUND: Perinatal death is one of the most difficult bereavements due to the shock and profound grief experienced by parents. It has been established that such bereavement has a life-lasting impact. Twin pregnancy is associated with increased perinatal risk, with higher rates of perinatal mortality than in singleton pregnancy. OBJECTIVES: To date, few studies have examined the effect of the loss of one twin diagnosed with a congenital abnormality during pregnancy...
October 11, 2016: Journal of Palliative Medicine
Luís Guedes-Martins
Chronic hypertension is frequently encountered during pregnancy and needs to be distinguished from other hypertensive complications of pregnancy, such as preeclampsia and gestational hypertension. The prevalence of this pregnancy complication is attributable to the increased prevalence of obesity and maternal age at childbearing. Women with chronic arterial hypertension are at increased risk for several pregnancy complications, including superimposed preeclampsia, caesarean delivery, preterm delivery <37 weeks gestation, birth weight <2500 g, neonatal unit admission, and perinatal death...
October 9, 2016: Advances in Experimental Medicine and Biology
Mary V Kinney, Jeffrey Michael Smith, Tanya Doherty, Jorge Hermida, Karen Daniels, José M Belizán
Hypertensive disorders of pregnancy (HDP), particularly pre-eclampsia and eclampsia, remain one of the leading causes of maternal mortality and are contributory in many foetal/newborn deaths. This editorial discusses a supplement of seven papers which provide the results of the first round of the CLIP (Community Level Interventions for Pre-eclampsia) Feasibility Studies. These studies report a number of enablers and barriers in each setting, which have informed the implementation of a cluster-randomized trial (cRCT) aimed at reducing pre-eclampsia-related, and all-cause, maternal and perinatal mortality and major morbidity using community-based identification and treatment of pre-eclampsia in selected geographies of Nigeria, Mozambique, Pakistan and India...
September 30, 2016: Reproductive Health
Susannah Hopkins Leisher, Zheyi Teoh, Hanna Reinebrant, Emma Allanson, Hannah Blencowe, Jan Jaap Erwich, J Frederik Frøen, Jason Gardosi, Sanne Gordijn, A Metin Gülmezoglu, Alexander E P Heazell, Fleurisca Korteweg, Joy Lawn, Elizabeth M McClure, Robert Pattinson, Gordon C S Smith, Ӧzge Tunçalp, Aleena M Wojcieszek, Vicki Flenady
BACKGROUND: Each year, about 5.3 million babies die in the perinatal period. Understanding of causes of death is critical for prevention, yet there is no globally acceptable classification system. Instead, many disparate systems have been developed and used. We aimed to identify all systems used or created between 2009 and 2014, with their key features, including extent of alignment with the International Classification of Diseases (ICD) and variation in features by region, to inform the World Health Organization's development of a new global approach to classifying perinatal deaths...
October 5, 2016: BMC Pregnancy and Childbirth
Joyce J Cheptum, Nelly Muiruri, Ernest Mutua, Moses Gitonga, Mwangi Juma
BACKGROUND: Death of a baby in-utero is a very devastating event to the mother and the family. Most stillbirths occur during labor and birth with other deaths occurring during the antenatal period. Millions of families experience stillbirths, yet these deaths remain uncounted, and policies have not been clearly stipulated to address this issue. The aim of the study was to identify the possible causes of stillbirths as recorded in the medical records. METHODS: A retrospective study looking at medical records of women who experienced stillbirths between 1(st) January 2009 and 31(st) December 2013 at Nyeri Provincial General Hospital, Kenya...
2016: Int J MCH AIDS
Jaime R Torres, Luiza H Falleiros-Arlant, Lourdes Dueñas, Jorge Pleitez-Navarrete, Doris M Salgado, José Brea-Del Castillo
BACKGROUND: During the years 2014 and 2015, the Region of the Americas underwent a devastating epidemic of chikungunya virus (CHIKV) of the Asian genotype, resulting in millions of affected individuals. However, epidemiological and clinical information on this experience is scarce. Prior knowledge of congenital and neonatal illness caused by CHIKV is limited and almost exclusively based on data obtained from a single outbreak of the East/Central/South African (ECSA) genotype. The effect of chikungunya fever (CHIKF) on pregnancy outcomes and its consequences for infants born to infected mothers at the peak of the epidemic wave in Latin America are reviewed herein...
September 13, 2016: International Journal of Infectious Diseases: IJID
Aleena M Wojcieszek, Hanna E Reinebrant, Susannah Hopkins Leisher, Emma Allanson, Michael Coory, Jan Jaap Erwich, J Frederik Frøen, Jason Gardosi, Sanne Gordijn, Metin Gulmezoglu, Alexander E P Heazell, Fleurisca J Korteweg, Elizabeth McClure, Robert Pattinson, Robert M Silver, Gordon Smith, Zheyi Teoh, Özge Tunçalp, Vicki Flenady
BACKGROUND: Despite the global burden of perinatal deaths, there is currently no single, globally-acceptable classification system for perinatal deaths. Instead, multiple, disparate systems are in use world-wide. This inconsistency hinders accurate estimates of causes of death and impedes effective prevention strategies. The World Health Organisation (WHO) is developing a globally-acceptable classification approach for perinatal deaths. To inform this work, we sought to establish a consensus on the important characteristics of such a system...
2016: BMC Pregnancy and Childbirth
E R Allanson, J P Vogel, Ӧ Tunçalp, J Gardosi, R C Pattinson, A Francis, Jjhm Erwich, V J Flenady, J F Frøen, J Neilson, A Quach, D Chou, M Mathai, L Say, A M Gülmezoglu
OBJECTIVE: We explore preterm-related neonatal deaths using the WHO application of the International Classification of Disease (ICD-10) to deaths during the perinatal period: ICD-PM as an informative case study, where ICD-PM can improve data use to guide clinical practice and programmatic decision-making. DESIGN: Retrospective application of ICD-PM. SETTING: South Africa, and the UK. POPULATION: Perinatal death databases...
November 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Heather Scott, Isabella Danel
In 2010, the United Nations (UN) launched the Global Strategy for Women's and Children's Health to accelerate progress on maternal and child health. A UN Commission on Information and Accountability, established to ensure oversight and accountability on women's and children's health, outlined a framework with three processes: monitor, review, and act. This paper assesses progress on these processes. Effective monitoring depends on a functional civil registration and vital statistics system. Review requires counting all deaths and identifying contributing factors...
June 23, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
A Bajracharya
Background Failure to plan a pregnancy can adversely affect the health of the family as a whole. High parity is related to increased maternal, perinatal and infant deaths and is associated with nutritional problems of both mother and child. Hence, good knowledge, attitude and practice of family planning among women are important. This study is aimed to determine the knowledge, attitude and practice of contraception among the postpartum women attending Kathmandu Medical College Teaching Hospital. Objective To determine the knowledge, attitude and the practice of various contraceptive methods among the postpartum women...
October 2015: Kathmandu University Medical Journal (KUMJ)
Caroline Agaro, Jolly Beyeza-Kashesya, Peter Waiswa, Juliet N Sekandi, Suzan Tusiime, Ronald Anguzu, Elizabeth Ekirapa Kiracho
BACKGROUND: Uganda like many developing countries still experiences high levels of maternal and perinatal deaths despite a decade of maternal and perinatal death review (MPDR) program. Oyam district has been implementing MPDR since 2008 with varying successes among the health facilities. This paper presents the factors that influence the conduct of maternal and perinatal death reviews in Oyam District, Uganda. METHODS: This was a cross-sectional study where both qualitative and quantitative data were collected...
2016: BMC Women's Health
Asif Raza Khowaja, Rahat Najam Qureshi, Diane Sawchuck, Olufemi T Oladapo, Olalekan O Adetoro, Elizabeth A Orenuga, Mrutyunjaya Bellad, Ashalata Mallapur, Umesh Charantimath, Esperança Sevene, Khátia Munguambe, Helena Edith Boene, Marianne Vidler, Zulfiqar A Bhutta, Peter von Dadelszen
BACKGROUND: Globally, pre-eclampsia and eclampsia are major contributors to maternal and perinatal mortality; of which the vast majority of deaths occur in less developed countries. In addition, a disproportionate number of morbidities and mortalities occur due to delayed access to health services. The Community Level Interventions for Pre-eclampsia (CLIP) Trial aims to task-shift to community health workers the identification and emergency management of pre-eclampsia and eclampsia to improve access and timely care...
2016: Reproductive Health
D Saldivar-Rodríguez, O R Treviño-Montemayor, A Guzmán-López, G Treviño-Martínez, C C Flores-Acosta
BACKGROUND: Acute pancreatitis is an inflammatory disease that affects the pancreatic tissue, which have been proposed numerous causes, with unpredictable results, it appears as a complication of rare occurrence, so the information on maternal and fetal complications is limited. Objective: Exposing obstetric and perinatal outcomes of patients diagnosed with pancreatitis complicating pregnancy. METHODOLOGY: A retrospective, observational, transverse and descriptive study; data were obtained and analyzed by reviewing medical records of patients diagnosed with pancreatitis and pregnancy...
February 2016: Ginecología y Obstetricia de México
Michael J Mahande, Joseph Obure
BACKGROUND: Both short and long interpregnancy intervals have been associated with an increased risk of adverse pregnancy outcomes. There is limited information about the impact of interpregnancy interval on pregnancy (IPI) outcomes in Tanzania. The objective of this study was to assess the effect of IPI on adverse pregnancy outcomes. METHODS: We performed a retrospective cohort study using maternally-linked data from Kilimanjaro Christian Medical Centre (KCMC) birth registry...
June 7, 2016: BMC Pregnancy and Childbirth
Fatih Şahiner
Zika virus (ZIKV) is an enveloped RNA virus that belongs to the Flaviviridae family. Although more than 60 years have passed since the discovery and first reported human cases of the virus, only a small number (< 10) of cases had been encountered in the literature until the last 10 years. Zika virus was known as a virus which caused sporadic infections and was confined to Africa and Asia along a narrow equatorial line. In 2007, however, the first major outbreak of ZIKV occurred in Yap Island (Micronesia), and so it was reported for the first time outside of Africa and Asia...
April 2016: Mikrobiyoloji Bülteni
W John Watkins, Sarah J Kotecha, Sailesh Kotecha
BACKGROUND: Low birthweight (LBW) is associated with increased mortality in infancy, but its association with mortality in later childhood and adolescence is less clear. We investigated the association between birthweight and all-cause mortality and identified major causes of mortality for different birthweight groups. METHODS AND FINDINGS: We conducted a population study of all live births occurring in England and Wales between 1 January 1993 and 31 December 2011...
May 2016: PLoS Medicine
Lorie M Harper, Joseph R Biggio, Sarah Anderson, Alan T N Tita
OBJECTIVE: To identify the gestational age of planned delivery in pregnancies complicated by chronic hypertension that minimizes the risk of perinatal death and severe adverse events. METHODS: This was a retrospective cohort study of all singletons complicated by hypertension. Detailed patient-level information was collected by chart review, including indication for delivery. Planned delivery at 36-36 6/7, 37-37 6/7, 38-38 6/7, and 39-39 6/7 weeks of gestation was compared with expectant management beyond each respective gestational age...
June 2016: Obstetrics and Gynecology
M Battin, L Sadler, V Masson, C Farquhar
AIM: To establish the incidence of moderate to severe neonatal encephalopathy (NE) in term infants from New Zealand and to document demographic characteristics and neonatal outcomes. METHODS: Cases were reported monthly via the New Zealand Paediatric Surveillance Unit (NZPSU). Data were collected from paediatricians for neonatal items and lead maternity carers for pregnancy and birth details. Term neonatal deaths in the Perinatal and Maternal Mortality Review Committee dataset that were because of hypoxia and/or neonatal deaths from hypoxic ischaemic encephalopathy were added to the cases identified via the NZPSU, if they had not previously been ascertained...
June 2016: Journal of Paediatrics and Child Health
Theonia K Boyd, Colleen Anne Wright, Hein Odendaal, Amy J Elliott, Mary Ann Sens, Rebecca Dunn Folkerth, Drucilla J Roberts, Hannah Kinney
OBJECTIVE: Describe the classification system for assigning the cause of stillbirth in the Safe Passage Study, an international, multi-institutional, prospective analysis conducted by the NIAAA/NICHD-funded Prenatal Alcohol in SIDS and Stillbirth (PASS) Research Network. The study mission is to determine the role of prenatal alcohol and/or cigarette smoke exposure in adverse pregnancy outcomes, including stillbirth, in a high-risk cohort of 12,000 maternal/fetal dyads. METHODS: The PASS Network classification system is based upon 5 'sites of origin' for cause of stillbirth, further subdivided into mechanism subcategories; both are employed to assign an ultimate cause of death...
April 26, 2016: Pediatric and Developmental Pathology
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