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https://www.readbyqxmd.com/read/28430735/sodium-tetradecyl-sulfate-a-review-of-clinical-uses
#1
Helena A Jenkinson, Kelly M Wilmas, Sirunya Silapunt
BACKGROUND: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have been reported. OBJECTIVE: To describe the clinical uses of STS, as well as efficacy and adverse effects. METHODS: Review of studies searchable on PubMed from 1938 to 2016 describing clinical uses of STS to determine efficacy and adverse effects associated with various applications...
April 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28427499/coexistent-venous-angioma-and-focal-cortical-dysplasia
#2
Richard A Prayson, Elizabeth E O'Toole
No abstract text is available yet for this article.
April 21, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/28415057/-de-novo-cavernous-angioma-secondary-to-a-developmental-venous-anomaly-a-case-report-and-review-of-the-literature
#3
Yohtaro Sakakibara, Yoshio Taguchi, Homare Nakamura, Hidetaka Onodera, Masashi Uchida, Kimiyuki Kawaguchi, Yoshio Aida
OBJECTIVE: Previously, cavernous angiomas(CAs)have been thought to be only congenital in origin. Recently, however, a few cases of de novo CAs have been reported in the literature. We present a case of a de novo CA and discuss the etiology of the newly appeared CA. CASE REPORT: A 29-year-old man was presented to a local clinic because of hypersomnia. MRI demonstrated a heterogeneous mass peripherally located, which was in contact with a developmental venous anomaly(DVA)at the left thalamus...
April 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28388566/genotype-phenotype-correlations-in-chinese-von-hippel-lindau-disease-patients
#4
Shuanghe Peng, Matthew J Shepard, Jiangyi Wang, Teng Li, Xianghui Ning, Lin Cai, Zhengping Zhuang, Kan Gong
von Hippel-Lindau (VHL) disease is caused by mutations in the VHL gene and demonstrates marked phenotypic variability. Genotype-phenotype correlations in Chinese VHL patients have been unclear. To establish genotype-phenotype correlations in Chinese VHL patients, we collected VHL mutations and phenotypes of 291 patients with VHL disease from 115 unrelated families. Genotype-phenotype correlations at mutation type level, mutation region level, and mutation codon level were analyzed by Kaplan-Meier curves and Cox regression models...
March 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28387823/synopsis-of-guidelines-for-the-clinical-management-of-cerebral-cavernous-malformations-consensus-recommendations-based-on-systematic-literature-review-by-the-angioma-alliance-scientific-advisory-board-clinical-experts-panel
#5
Amy Akers, Rustam Al-Shahi Salman, Issam A Awad, Kristen Dahlem, Kelly Flemming, Blaine Hart, Helen Kim, Ignacio Jusue-Torres, Douglas Kondziolka, Cornelia Lee, Leslie Morrison, Daniele Rigamonti, Tania Rebeiz, Elisabeth Tournier-Lasserve, Darrel Waggoner, Kevin Whitehead
BACKGROUND: Despite many publications about cerebral cavernous malformations (CCMs), controversy remains regarding diagnostic and management strategies. OBJECTIVE: To develop guidelines for CCM management. METHODS: The Angioma Alliance ( www.angioma.org ), the patient support group in the United States advocating on behalf of patients and research in CCM, convened a multidisciplinary writing group comprising expert CCM clinicians to help summarize the existing literature related to the clinical care of CCM, focusing on 5 topics: (1) epidemiology and natural history, (2) genetic testing and counseling, (3) diagnostic criteria and radiology standards, (4) neurosurgical considerations, and (5) neurological considerations...
April 7, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28378288/development-of-cystic-malacia-after-high-dose-cranial-irradiation-of-pediatric-cns-tumors-in-long-term-follow-up
#6
Fumiyuki Yamasaki, Takeshi Takayasu, Ryo Nosaka, Ikuno Nishibuchi, Hiroshi Kawaguchi, Manish Kolakshyapati, Shumpei Onishi, Taiichi Saito, Kazuhiko Sugiyama, Masao Kobayashi, Kaoru Kurisu
PURPOSE: The purpose of this study is to investigate the incidence of cystic malacia in long-term survivors of pediatric brain tumors treated with high-dose cranial irradiation. MATERIALS AND METHODS: Between 1997 and 2015, we treated 41 pediatric patients (26 males, 15 females; age ranging from 3.3 to 15.7 years, median 9-year-old) of pediatric brain tumors [17 medulloblastomas, 7 primitive neuroectodermal tumors (PNET), 3 pineoblastomas, 6 non-germinomatous germ cell tumors (NGGCT), 8 gliomas (including 4 ependymomas, 1 anaplastic astrocytoma, 1 oligodendroglioma, 1 pilocytic astrocytoma, 1 astroblastoma)] with high-dose craniospinal irradiation...
April 4, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28302694/incidental-littoral-cell-angioma-in-refractory-immune-thrombocytopenic-purpura
#7
Juli-Anne Gardner, Katherine Devitt
No abstract text is available yet for this article.
March 16, 2017: Blood
https://www.readbyqxmd.com/read/28298028/intracranial-intraaxial-cerebral-tufted-angioma-case-report
#8
Randy S D'Amico, George Zanazzi, Gunnar Hargus, Timothy Dyster, Shirley Chan, Angela Lignelli-Dipple, Tony J C Wang, Phyllis L Faust, Guy M McKhann
Tufted angioma (TA) is a rare, slow-growing, vascular lesion that commonly presents as a solitary macule, papule, or nodule arising in the soft tissues of the torso, extremities, and head and neck in children and young adults. Adult-onset cases have been infrequently reported. While typically benign, TAs may be locally aggressive. Complete physical examination and hematological workup are recommended in patients with TA to exclude the presence of Kasabach-Merritt phenomenon (KMP). The authors describe the case of a 69-year-old man with a contrast-enhancing frontal lobe lesion, with surrounding vasogenic edema, which was treated by gross-total resection...
February 24, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28293056/myoid-angioendothelioma-of-the-spleen-a-rare-case-report-and-literature-review
#9
Bita Geramizadeh, Mohammadhossein Anbardar, Seyed-Ali Malekhosseini
Most common tumors of the spleen are hematologic and lymphoid malignancies. Non-lymphoid and non-hematologic tumors of the spleen are very rare, the most common of which are vascular tumors. This group of tumors in the spleen is composed of heterogeneous tumors such as hemangioma, angioendothelioma (AE), littoral cell angioma, and angiosarcoma. There are several histologic forms of AE such as epithelioid AE, Kaposiform AE, and myoid AE. Among these splenic vascular tumors, myoid angioendothelioma (MAE) seems to be the least common type...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28289757/optimization-of-the-surgical-approach-in-avms-using-mri-and-4d-dsa-fusion-technique-a%C3%A2-technical-note
#10
S Tritt, B Ommer, S Gehrisch, S Klein, V Seifert, J Berkefeld, J Konczalla
PURPOSE: Previously published data demonstrated the possibility of displaying the angioarchitecture of intracranial vascular malformations using time-resolved 3D imaging (4D digital subtraction angiography [DSA]). The purpose of our study was to prove the technical feasibility of creating fused images of time-resolved 3D reconstructions and MPRAGE MRI data sets and to check the reliability of the correct anatomical display of the angioma nidus and the venous drainage in the fused images of patients with intracranial arteriovenous malformations (AVM)...
March 13, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28274277/the-efficacy-of-resection-of-an-intradural-extramedullary-foramen-magnum-cavernous-malformation-presenting-with-repeated-subarachnoid-hemorrhage-a-case-report
#11
Tomoya Oishi, Naoto Sakai, Tetsuro Sameshima, Hiroshi Kawaji, Hiroki Namba
BACKGROUND: Intradural extramedullary cavernous angiomas of the central nervous system are a rare type of cavernous angioma, but they can cause fatal subarachnoid hemorrhage. The efficacy of resection for this type of cavernous malformations remains uncertain. This is the first report to recommend surgical resection of these types of lesions regardless of the fatal condition. CASE PRESENTATION: Our patient was a 70-year-old Japanese man who experienced a sudden onset of an occipital headache, followed by bilateral abducens nerve palsy...
March 9, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28255959/a-novel-ccm1-krit1-heterozygous-nonsense-mutation-c-1864c-t-associated-with-familial-cerebral-cavernous-malformation-a-genetic-insight-from-an-8-year-continuous-observational-study
#12
Chenlong Yang, Van Halm-Lutterodt Nicholas, Jizong Zhao, Bingquan Wu, Haohao Zhong, Yan Li, Yulun Xu
Cerebral cavernous malformation (CCM) is a congenital vascular abnormality that predominantly affects the central nervous system, but that sometimes encroaches other vital tissues, including the retina, skin, and even liver. The familial form of CCM (FCCM) is considered to be an autosomal dominant disease with incomplete penetrance and variable expression, which is often attributed to mutations in three genes: CCM1, CCM2, and CCM3. We screened a Chinese family diagnosed with FCCM by using Sanger sequencing...
March 2, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28252554/clinical-and-dermoscopic-features-of-truly-amelanotic-plantar-melanoma
#13
Vincenzo De Giorgi, Alessia Gori, Imma Savarese, Antonietta D'Errico, Federica Papi, Marta Grazzini, Federica Scarfì, Piero Covarelli, Daniela Massi
Currently, there are no specific clinical and dermoscopic features for diagnosing truly amelanotic plantar melanoma (TAPM). The present study aimed to investigate the dermoscopic features of all clinical variants of TAMPS and to evaluate their histopathological correlations. A retrospective analysis of prospectively collected data was carried out during a 10-year period (2003-2013). We analyzed the clinical data of 1321 patients, who had received a histological diagnosis of melanoma at the Melanoma Unit of the University of Florence...
June 2017: Melanoma Research
https://www.readbyqxmd.com/read/28211879/evaluation-of-choroidal-tumors-with-optical-coherence-tomography-enhanced-depth-imaging-and-oct-angiography-features
#14
G Cennamo, M R Romano, M A Breve, N Velotti, M Reibaldi, G de Crecchio, G Cennamo
AimTo describe the vascular features of choroidal tumors using enhanced depth imaging (EDI), optical coherence tomography (OCT), and OCT-angiography.MethodsIn this prospective study, we evaluated 116 Caucasian patients with choroidal tumors (60 eyes with choroidal nevi, 40 with choroidal melanoma, 6 with choroidal hemangioma, 2 with optic disc melanocytoma, 6 with choroidal osteoma, and 2 with retinal metastases). Patients underwent a complete ophthalmic examination including bulbar echography, EDI-OCT, OCT-angiography, and multicolor imaging...
February 17, 2017: Eye
https://www.readbyqxmd.com/read/28191336/rare-cervical-intramedullary-cavernous-angioma-with-trigeminal-neuralgia-and-cervical-itch-case-report-and-review-of-the-literature
#15
Gong Shuhui, Liu Jiagang, Huang Siqing, Chen Haifeng, Tang Qingrong, Zhao Bohao
INTRODUCTION: Intramedullary cavernous angioma (ICA) is a rare lesion of the spinal cord, representing only 3% - 5% of central nervous system lesions. The coexistence of trigeminal neuralgia and refractory itch is very rarely encountered in clinical practice. To our knowledge, a report of an ICA with trigeminal neuralgia and local neuropathic itch has never been published to date. Thus, we present a very interesting case of a C2 ICA. CASE PRESENTATION: A 61-year-old female presented with right facial pain for three years, which was exacerbated by accompanying cervical pain and itch for one month...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28120074/management-of-cerebral-radiation-necrosis-a-retrospective-study-of-12-patients
#16
Chenlong Liao, Massimiliano Visocchi, Wenchuan Zhang, Min Yang, Wenxiang Zhong, Pengfei Liu
BACKGROUND: Cerebral radiation necrosis (RN) is a severe complication of radiotherapy for cerebral pathologies. This study discusses the radiographic and pathological features of 12 patients with RN and investigates the management strategy. METHODS: Eleven patients with brain tumors, and one with cerebral cavernous angioma, treated by surgical resection or Gamma Knife alone before radiotherapy developed RN during follow-up. Surgical resection for the cerebral RN was performed in nine patients, and the other three patients received medical treatment...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28106693/a-tentorial-cavernous-angioma-with-hemorrhage-mimicking-a-hypervascular-brain-tumor
#17
Xiaodong Shi, Qiyong Jiang, Xiaogang Liu, Xunhui Yuan, Gaoling Sun, Jianyi Niu, Liemei Guo
No abstract text is available yet for this article.
January 18, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28104017/-lymphadenectomy-using-dissection-and-protection-of-carotid-sheath-and-main-nerves-in-surgery-for-benign-diseases-in-the-neck
#18
J Wu, Y H Liu, K L Wu, X H Li, C B Gao, Y Zhao
Objective: To investigate the significance of lymphadenectomy using dissection and protection of carotid sheath and main nerves in treating complex benign disease of neck. Methods: A total of 54 cases with benign diseases in neck who received the protective surgical treatments were reviewed. There were 25 cases of recurrent branchial fistula, 15 cases of lymphoid tuberculosis, 5 cases of cystic hygroma, 5 cases of racemose angioma, and 4 cases of Madelung's disease. According to the location and extent of disease, all cases received operation with dissection and protection of carotid sheath and main nerves to removal lesions with lymphoid tissue and fat-connective tissue...
January 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28078663/inhibition-of-hsp90-exerts-anti-tumor-effect-on-angiosarcoma-involvement-of-vegf-signaling-pathway
#19
S Yamada-Kanazawa, I Kajihara, S Fukushima, M Jinnin, M Masuzawa, M Masuzawa, Y Amoh, D Hoshina, R Abe, H Ihn
BACKGROUND: Angiosarcoma is a rare malignant neoplasm derived from endothelial cells and its prognosis is poor because advanced angiosarcoma is resistant to standard chemotherapy, and new therapies are urgently needed. Heat shock protein 90 (HSP90) has been identified as a molecular chaperone that regulates various cancer-related proteins. Numerous clinical trials are testing the effectiveness of HSP90 inhibitors in various types of malignancies. OBJECTIVES: To investigate the role of HSP90 in the pathogenesis of angiosarcoma and whether inhibition of HSP90 may have anti-tumor activity...
January 12, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28072736/von-hippel-lindau-disease-involving-pancreas-and-biliary-system-a-rare-case-report
#20
Xu-Ting Zhi, Qi-Yu Bo, Feng Zhao, Dong Sun, Tao Li
RATIONALE: Von Hippel-Lindau (VHL) disease is a rare inherited, autosomal-dominant syndrome caused by heterozygous germline mutations in the VHL gene. VHL patients are prone to develop benign and malignant tumors and cysts in multiple organ systems involving kidneys, pancreas and central nervous system (CNS). The varied and complex clinical manifestations and radiological findings of VHL are of interest. PATIENT CONCERNS: We report a 38-year-old woman with a ten-year history of VHL disease involving both pancreas and biliary system...
January 2017: Medicine (Baltimore)
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