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https://www.readbyqxmd.com/read/28335624/effects-of-patient-preferences-on-outcomes-in-the-predictors-of-remission-in-depression-to-individual-and-combined-treatments-predict-study
#1
Boadie W Dunlop, Mary E Kelley, Vivianne Aponte-Rivera, Tanja Mletzko-Crowe, Becky Kinkead, James C Ritchie, Charles B Nemeroff, W Edward Craighead, Helen S Mayberg
OBJECTIVE: The Predictors of Remission in Depression to Individual and Combined Treatments [PReDICT] study aimed to identify clinical and biological factors predictive of treatment outcomes in major depressive disorder among treatment-naive adults. The authors evaluated the efficacy of cognitive-behavioral therapy (CBT) and two antidepressant medications (escitalopram and duloxetine) in patients with major depression and examined the moderating effect of patients' treatment preferences on outcomes...
March 24, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28333274/making-room-for-interactivity-using-the-cloud-based-audience-response-system-nearpod-to-enhance-engagement-in-lectures
#2
Stephen McClean, William Crowe
Active and collaborative learning provide distinct advantages for students in higher education, yet can often be hampered by the barrier of large class sizes. Solutions that combine a "bring your own device culture" (BOYD) with cloud-based technologies may facilitate a more interactive learning experience. In this pilot study we describe the use of one such technology, Nearpod, to enhance interactivity in lectures delivered to pharmacy and bioscience students at Ulster University. Existing material in PowerPoint or Keynote format is uploaded to the instructor area of Nearpod, interactive elements are added, and the lecture is then broadcast via the internet to student devices...
March 8, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28331583/surreptitious-sympatry-exploring-the-ecological-and-genetic-separation-of-two-sibling-species
#3
Line S Cordes, Gregory O'Corry-Crowe, Robert J Small
Climate change is having profound impacts on animal populations, and shifts in geographic range are predicted in response. Shifts that result in range overlap between previously allopatric congeneric species may have consequences for biodiversity through interspecific competition, hybridization, and genetic introgression. Harbor seals (Phoca vitulina) and spotted seals (Phoca largha) are parapatric sibling species and areas of co-occurrence at the edges of their range, such as Bristol Bay, Alaska, offer a unique opportunity to explore ecological separation and discuss potential consequences of increased range overlap resulting from retreating sea ice...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28324202/the-influence-of-surgical-approach-on-postoperative-pelvic-tilt-after-total-hip-arthroplasty
#4
Daisuke Inoue, Tamon Kabata, Yoshitomo Kajino, Tadashi Taga, Kazuhiro Hasegawa, Takashi Yamamoto, Tomoharu Takagi, Takaaki Ohmori, Hiroyuki Tsuchiya
BACKGROUND: Past reports have shown the tendency of posterior pelvic tilt to increase over time after total hip arthroplasty (THA). We have hypothesized that the volume and extent of released joint capsule may influence the change in postoperative pelvic tilt. This study was conducted to ascertain whether surgical approach during THA (posterior or anterior) has an effect on postoperative changes in pelvic tilt. METHODS: We conducted a retrospective review of 81 hips in 60 patients...
March 21, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28323477/-the-service-i-rendered-was-just-as-true-african-american-soldiers-and-veterans-as-activist-patients
#5
Jessica L Adler
In this article, I examine how African American soldiers and veterans experienced and shaped federally sponsored health care during and after World War I. Building on studies of the struggles of Black leaders and health care providers to win professional and public health advancement in the 1920s and 1930s, and of advocates to mobilize for health care rights in the mid-20th century, I focus primarily on the experiences and activism of patients in the interwar years. Private and government correspondence, congressional testimony, and reports from Black newspapers reveal that African American soldiers and veterans communicated directly with policymakers and bureaucrats regarding unequal treatment, assuming roles as "policy actors" who viewed health and medical care as "politics by other means...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28318514/incorporating-comorbidity-within-risk-adjustment-for-uk-pediatric-cardiac-surgery
#6
Katherine L Brown, Libby Rogers, David J Barron, Victor Tsang, David Anderson, Shane Tibby, Thomas Witter, John Stickley, Sonya Crowe, Kate English, Rodney C Franklin, Christina Pagel
BACKGROUND: When considering early survival rates after pediatric cardiac surgery it is essential to adjust for risk linked to case complexity. An important but previously less well understood component of case mix complexity is comorbidity. METHODS: The National Congenital Heart Disease Audit data representing all pediatric cardiac surgery procedures undertaken in the United Kingdom and Ireland between 2009 and 2014 was used to develop and test groupings for comorbidity and additional non-procedure-based risk factors within a risk adjustment model for 30-day mortality...
March 15, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28318513/improving-risk-adjustment-for-mortality-after-pediatric-cardiac-surgery-the-uk-prais2-model
#7
Libby Rogers, Katherine L Brown, Rodney C Franklin, Gareth Ambler, David Anderson, David J Barron, Sonya Crowe, Kate English, John Stickley, Shane Tibby, Victor Tsang, Martin Utley, Thomas Witter, Christina Pagel
BACKGROUND: Partial Risk Adjustment in Surgery (PRAiS), a risk model for 30-day mortality after children's heart surgery, has been used by the UK National Congenital Heart Disease Audit to report expected risk-adjusted survival since 2013. This study aimed to improve the model by incorporating additional comorbidity and diagnostic information. METHODS: The model development dataset was all procedures performed between 2009 and 2014 in all UK and Ireland congenital cardiac centers...
March 15, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28301908/identification-of-cost-saving-opportunities-for-the-use-of-antithrombin-iii-in-adult-and-pediatric-patients
#8
Alana Ciolek, John Lindsley, Jessica Crow, Kristen Nelson-McMillan, David Procaccini
Thrombate III is a human plasma-derived antithrombin III (AT-III) often utilized in patients on extracorporeal membrane oxygenation (ECMO) with suspected AT-III-mediated heparin resistance. It is supplied as 500-U and 1000-U vials, costing US$4.66 per unit. Literature is limited in describing the clinical value of AT-III in relation to its high cost. The primary objective was to determine conditions of use and associated cost of potentially unnecessary utilization of AT-III at The Johns Hopkins Hospital. Secondary objectives included evaluating the effect of AT-III on anticoagulation parameters and the overall cost utilized and wasted on AT-III...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28300075/a-human-antibody-against-zika-virus-crosslinks-the-e-protein-to-prevent-infection
#9
S Saif Hasan, Andrew Miller, Gopal Sapparapu, Estefania Fernandez, Thomas Klose, Feng Long, Andrei Fokine, Jason C Porta, Wen Jiang, Michael S Diamond, James E Crowe, Richard J Kuhn, Michael G Rossmann
The recent Zika virus (ZIKV) epidemic has been linked to unusual and severe clinical manifestations including microcephaly in fetuses of infected pregnant women and Guillian-Barré syndrome in adults. Neutralizing antibodies present a possible therapeutic approach to prevent and control ZIKV infection. Here we present a 6.2 Å resolution three-dimensional cryo-electron microscopy (cryoEM) structure of an infectious ZIKV (strain H/PF/2013, French Polynesia) in complex with the Fab fragment of a highly therapeutic and neutralizing human monoclonal antibody, ZIKV-117...
March 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28299858/psychoeducation-for-bipolar-disorder-a-discourse-analysis
#10
Lynere Wilson, Marie Crowe, Anne Scott, Cameron Lacey
Psychoeducation has become a common intervention within mental health settings. It aims to increase people's ability to manage a life with a long-term illness. For people with bipolar disorder, psychoeducation is one of a range of psychosocial interventions now considered part of contemporary mental health practice. It has taken on a 'common sense' status that results in little critique of psychoeducation practices. Using a published manual on psychoeducation and bipolar disorder as its data, Foucauldian discourse analysis was used in the present study for a critical perspective on psychoeducation in order to explore the taken-for-granted assumptions on which it is based...
March 16, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/28295820/comparison-of-readout-segmented-and-conventional-single-shot-for-echo-planar-diffusion-weighted-imaging-in-the-assessment-of-kidney-interstitial-fibrosis
#11
Iris Friedli, Lindsey Alexandra Crowe, Thomas de Perrot, Lena Berchtold, Pierre-Yves Martin, Sophie de Seigneux, Jean-Paul Vallée
PURPOSE: To compare readout-segmented echo-planar imaging (EPI) (RESOLVE) to single-shot EPI (ss-EPI) diffusion-weighted imaging (DWI) for the assessment of renal interstitial fibrosis. MATERIALS AND METHODS: A phantom, eight healthy volunteers (under 30 years to avoid age-fibrosis related) and 27 chronic kidney disease (CKD) patients (scheduled for kidney biopsy) were scanned (at 3T) with ss-EPI and 5-shot RESOLVE DWI (resolution: 2 × 2 × 5 mm(3) , 10 b-values)...
March 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28295411/how-a-working-day-induced-tiredness-may-alter-some-facial-signs-in-differently-aged-caucasian-women
#12
Flament Frederic, Pierre Julien, Delhommeau Karine, Adam Anne-Sophie
OBJECTIVES: To assess the alterations of some facial clinical signs after a working day in French Caucasian women. METHODS: Standardized photographs of full faces of 111 women of two different age-classes were taken before and after a working day. Photos were submitted in blind (morning or evening) to a panel of 10 experts for scoring the severity of 8 different facial signs using specific scales as established by previously published referential skin atlases. A panel of 60 naïve women gave their assessment of the overall look (more or less tired, aged, dull) from paired (morning/evening) photos given in blind...
March 15, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28294686/utility-of-combining-whole-genome-sequencing-with-traditional-investigational-methods-to-solve-foodborne-outbreaks-of-salmonella-infections-associated-with-chicken-a-new-tool-for-tackling-this-challenging-food-vehicle
#13
Samuel J Crowe, Alice Green, Kimberly Hernandez, Vi Peralta, Lyndsay Bottichio, Stephanie Defibaugh-Chavez, Aphrodite Douris, Laura Gieraltowski, Kelley Hise, Karen La-Pham, Karen P Neil, Mustafa Simmons, Glenn Tillman, Beth Tolar, Darlene Wagner, Jamie Wasilenko, Kristin Holt, Eija Trees, Matthew E Wise
High consumption rates and a multitude of brands make multistate foodborne outbreaks of Salmonella infections associated with chicken challenging to investigate, but whole genome sequencing is a powerful tool that can be used to assist investigators. Whole genome sequencing of pathogens isolated from clinical, environmental, and food samples is increasingly being used in multistate foodborne outbreak investigations to determine with unprecedented resolution how closely related these isolates are to one another genetically...
March 15, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28292531/stress-overeating-and-obesity-insights-from-human-studies-and-preclinical-models
#14
REVIEW
Maria Razzoli, Carolyn Pearson, Scott Crow, Alessandro Bartolomucci
Eating disorders and obesity have become predominant in human society. Their association to modern lifestyle, encompassing calorie-rich diets, psychological stress, and comorbidity with major diseases are well documented. Unfortunately the biological basis remains elusive and the pharmacological treatment inadequate, in part due to the limited availability of valid animal models. Human research on binge eating disorder (BED) proves a strong link between stress exposure and bingeing: state-levels of stress and negative affect are linked to binge eating in individuals with BED both in laboratory settings and the natural environment...
March 11, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28291651/challenges-in-total-hip-arthroplasty-in-the-setting-of-developmental-dysplasia-of-the-hip
#15
Eric M Greber, Christopher E Pelt, Jeremy M Gililland, Mike B Anderson, Jill A Erickson, Christopher L Peters
BACKGROUND: Developmental dysplasia of the hip (DDH) is a recognized cause of secondary arthritis, which may eventually lead to total hip arthroplasty (THA). An understanding of the common acetabular and femoral morphologic abnormalities will aid the surgeon in preparing for the complexity of the surgical case. METHODS: We present the challenges associated with acetabular and femoral morphologies that may be present in the dysplastic hip and discuss surgical options to consider when performing THA...
February 22, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28291495/an-assessment-of-national-emt-certification-among-enlisted-military-medics
#16
Stephen Harper, Remle Crowe, Melissa Bentley, Chetan Kharod, Benjamin Walrath
BACKGROUND: Navy Hospital Corpsmen (HMs) are the Navy equivalent to Emergency Medical Technicians (EMTs) both in-garrison and on the battlefield. In 2000, the Emergency Medical Services (EMS) Education Agenda for the Future highlighted the need for a single certification agency to provide consistent evaluation of entry level competence for each nationally recognized EMS provider level. Administered by the National Registry of EMTs (NREMT), National EMT Certification is currently utilized by 46 states, the District of Columbia, four territories, and six federal organizations as part of their processes for granting licensure...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291339/ubiquitin-chain-enrichment-middle-down-mass-spectrometry-ubichem-ms-enables-characterization-of-branched-ubiquitin-chains-in-cellulo
#17
Sean O Crowe, Ambar S J B Rana, Kirandeep K Deol, Ying Ge, Eric R Strieter
Ubiquitin has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles of ubiquitin chains, however, is difficult due to their complex chain topologies. Branched ubiquitin chains are particularly challenging, as multiple modifications on a single ubiquitin preclude the use of standard bottom-up proteomic approaches. Developing methods to overcome these challenges is crucial considering evidence suggesting branched chains regulate the stability of proteins...
March 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28279900/electrochemical-oxidation-of-cyanide-on-3d-ti-ruo2-anode-using-a-filter-press-electrolyzer
#18
Tzayam Pérez, Rosa L López, José L Nava, Isabel Lázaro, Guillermo Velasco, Roel Cruz, Israel Rodríguez
The novelty of this communication lies in the use of a Ti-RuO2 anode which has not been tested for the oxidation of free cyanide in alkaline media at concentrations similar to those found in wastewater from the Merrill Crowe process (100 mg L(-1) KCN and pH 11), which is typically used for the recovery of gold and silver. The anode was prepared by the Pechini method and characterized by SEM. Linear sweep voltammetries on a Ti-RuO2 rotating disk electrode (RDE) confirmed that cyanide is oxidized at 0.45 < E < 1...
February 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/28279112/tips-on-building-resilience-and-improving-well-being
#19
Liz Crowe
Poor staff retention in emergency nursing is unsurprising given that nurses who work in emergency departments (EDs) can often experience compassion fatigue, burnout and post-traumatic stress disorder. Can a passion for a profession that involves so much illness, trauma and death be enough to sustain people through their working days?
March 10, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28276133/plasmid-mediated-resistance-to-cephalosporins-and-quinolones-in-escherichia-coli-from-american-crows-in-the-usa
#20
Ivana Jamborova, Monika Dolejska, Ludek Zurek, Andrea K Townsend, Anne B Clark, Julie C Ellis, Ivo Papousek, Alois Cizek, Ivan Literak
American crow (Corvus brachyrhynchos) feces were tested for Escherichia coli with plasmid-mediated quinolone resistance (PMQR), extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases. A total of 590 fecal samples were collected at four roosting sites in the USA and cultivated on selective media. Pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST) were performed to assess clonality. Transferability of resistance genes was studied using conjugation and transformation bioassays...
March 9, 2017: Environmental Microbiology
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