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M Nazou, E Parlapani, E-I Nazlidou, P Athanasis, V P Bozikas
Thyroid hormones are crucial in adult brain metabolic activity. As a result, abnormal thyroid gland function and in particular hypofunction, might cause principally depression and neurocognitive dysfunction. Psychosis, presented mainly with thought disorders and perceptual disturbances, is a much rarer manifestation of hypothyreoidism. A correlation between hypothyreoidism and psychosis has been described since 1888, especially in cases of advanced hypothyreoidism. A few years later (1949), Asher first added the terminology "myxedema madness" to the literature...
April 2016: Psychiatrikē, Psychiatriki
Diogo C Carvalho, Tauana S Tironi, Denise S Freitas, Rodrigo Kleinpaul, Natalia C Talim, Marco A Lana-Peixoto
The relationship between Sjögren's syndrome (SS) and neuromyelitis optica spectrum disorder (NMOSD) is not completely understood. We report two patients with both conditions and review 47 other previously reported cases meeting currently accepted diagnostic criteria, from 17 articles extracted from PubMed. Out of 44 patients whose gender was informed, 42 were females. Mean age at onset of neurological manifestation was 36.2 years (10-74). Serum anti-AQP4-IgG was positive in 32 patients, borderline in 1, and negative in 4...
August 2014: Arquivos de Neuro-psiquiatria
Miro Kasum, Slavko Oresković, Davor Jezek
Spontaneous forms of the ovarian hyperstimulation syndrome (sOHSS) are nearly always reported between 8 and 14 weeks of pregnancy and also with follicle-stimulating hormone (FSH) producing pituitary adenoma. The syndrome has been previously reported in rare instances of increased production of human chorionic gonadotrophin (hCG) such as multiple pregnancies, hydatiforme mole, polycystic ovary disease and elevated concentrations of thyroid-stimulating hormone (TSH) in hypothyreoidism. High levels of these hormones are able to stimulate by natural promiscuous activation the wild-type FSHr, resulting in sporadic presentations of the syndrome...
June 2013: Collegium Antropologicum
Gerhard Lutz
In the literature of the past 30 years there are only some publications concerned with hair loss and hyperprolactinemia in women. Therefore, the relevance of hyperprolactinemia was evaluated in 40 women with diffuse alopecia.Hair loss was assessed by clinical appearance and the pluck trichogram. 82.5% of the female patients had diffuse hair loss and 17.5% had androgenetic alopecia.The highest prolactin values measured were 1390 ng/ml and 255 ng/ml. Six patients had values between 150-80.4 ng/ml and 10 between 79...
January 1, 2012: Dermato-endocrinology
Dorothee Wachter, Nicole Gondermann, Matthias F Oertel, Ulf Nestler, Veit Rohde, Dieter-Karsten Böker
Recent studies investigating pituitary function after non-sellar brain tumor surgery showed that up to 38.2% of patients have pituitary insufficiency (PI). It has been assumed that the operation causes the PI, but preoperative hormone testing, which would have been necessary to prove this assumption, was not performed. The objective of this study is to answer the question if indeed microsurgery is the culprit of PI in patients with operatively treated non-sellar brain tumors. In this prospective trial, 54 patients with supratentorial non-sellar tumors were included...
October 2011: Neurosurgical Review
Petri Bono, Juhana Rautiola, Tapio Utriainen, Heikki Joensuu
UNLABELLED: Hypertension and hypothyreoidism are frequent side effects of VEGFR-inhibitors. We investigated whether hypertension or hypothyreoidism diagnosed during sunitinib treatment is associated with treatment efficacy. MATERIAL AND METHODS: Sixty-four consecutive patients with metastatic renal cell cancer (RCC) were treated with sunitinib in a single center. Hypertension was defined as persistent blood pressure >150/100 mmHg or blood pressure requiring intensification of pre-existing anti-hypertensive medication...
May 2011: Acta Oncologica
Hanna O Mäenpää, Matti J Välimäki
While papillary and follicular thyroid cancer usually has an excellent prognosis, recurrent and aggressive forms of the disease do occur. The success of surgical excision and radioiodine therapy is evaluated by ultrasonography of the neck, and TSH-stimulated serum thyreoglobulin. Based on investigational results, the patients are divided into three groups: the cancer does not exist, may exist or remains. This classification determines the thyroxine dose and follow-up arrangements. In cancer-free patients, thyroxine therapy will be implemented as in ordinary hypothyreoidism...
2010: Duodecim; Lääketieteellinen Aikakauskirja
C Müller, H Reuter, C Dohmen
Quetiapine is an atypical antipsychotic approved for the treatment of patients with psychotic disorders. Since approvement several case reports about intoxication with quetiapine were linked mainly with tachycardia, QT(c)-prolongation, somnolence, and hyperglycemia. Here, we present the first case report of an intoxication with an extreme overdose of quetiapine (36 g), ingested by a 32-year-old female (62 kg bodyweight) to attempt suicide. Symptoms associated with intoxication were coma without arterial hypotension, persistent tachycardia, hyperglycemia, and transient hypothyreoidism...
2009: Case Reports in Medicine
Srećko Severinski, Srdan Banac, Neda Smiljan Severinski, Vladimir Ahel, Katarina Cvijović
The aim of the study was to evaluate the natural course and potential risk factors of autoimmune thyroiditis (AIT) and thyroid dysfunction, and their influences on growth and glycemic control in children and adolescents with type 1 diabetes mellitus (T1D). The study comprised 148 subjects (age range 1-21 years; males 51%) with T1D. During the interval of 12 years serum levels of thyroid peroxidase (anti-TPO) and thyroglobulin (anti-TG) autoantibodies, thyroid-stimulating hormone (TSH) and tyroksine (T4), were screened annually...
March 2009: Collegium Antropologicum
S Höpfner, N Koehler, B Höpfner, E W Rauterberg
BACKGROUND: Since widespread screenings for hypothyreosis were started in 1981 in Germany, the numbers of mental and physical handicaps due to hypothyroidism are reduced markedly. The aim of this study is to evaluate the actual efficiency of the newborn screenings in Germany using in the federal state "Hessen". METHODS/SUBJECTS: All children born between 1988 and 1992 with suspicions laboratory results in the screening examination were contacted personally and statements concerning the screening itself and the physical and mental development were gathered from their parents, doctors and teachers...
July 2007: Klinische Pädiatrie
No abstract text is available yet for this article.
March 23, 1955: Acta Medica Scandinavica
C Keuneke, D Schlöndorff
Hypothyroidism with thyroglobulin antibodies during corticoid replacement in a 54-year-old man with isolated ACTH deficiency. HISTORY AND ADMISSION FINDINGS: A 54-year-old previously healthy man was admitted because of fatigue, tiredness, diarrhoea and weight loss for the last 3 years. Physical examination revealed dry but normally pigmented skin and markedly reduced Achilles reflex bilaterally. INVESTIGATIONS: Erythrocyte sedimentation rate was slightly elevated at 32 mm/h, C-reactive protein was normal. Both haemoglobin (12...
2000: Deutsche Medizinische Wochenschrift
D Trejbal, D Petrasova, H Wagnerova
The authors evaluated serum level of prolactin (PRL) and interleukin 2 (IL-2) before and after i.v. application of tyreoliberin (TRH) 0.2 mg in 10 women as controls and 10 women with primary hypothyreoidism. In controls, there was a significant increase of IL-2 20 min following application of TRH (IL-2 0 min: 17.95 +/- 11.69, IL-2 in 20 min: 33.36 +/- 17.73 fmol/l), in patients with hypothyreoidism the serum level of IL-2 decreased (IL-2 0 min: 31.32 +/- 19.0, IL-2 in 20 min: 19.11 +/- 17.8 fmol/l). The basal concentration of IL-2 in patients with hypothyreoidism was significantly higher as in controls (p < 0...
2001: Bratislavské Lekárske Listy
B Amann, R Stampfer, F Schmidt, P Mikhaiel, B Hummel, A Sterr, M Schäfer, H Grunze
In the actual version of the WHO diagnostic guidelines, the ICD-10, subtypes of bipolar disorder are not specified, in contrast to the American DSM-IV, where bipolar disorder has already been differentiated in bipolar I (severe manic and depressive episodes) and bipolar II disorder (depressive and hypomanic episodes). Furthermore, aspects of the longitudinal course of the illness, like rapid cycling (RC), are reflected as well. Rapid cycling is defined as four or more affective episodes within one year of the illness...
December 2001: Fortschritte der Neurologie-Psychiatrie
A Dyszkiewicz, E J Kucharz
Alterations in the finger microcirculation in patients with disturbed function of the thyroid gland was evaluated with planimetric photoplethysmography. One-hundred forty-one patients with disturbed thyroid function (31 overt hyperthyreoidism, 10 latent hyperthyreoidism, 79 overt hypothyreoidism, 22 latent hypothyroidism) and 30 healthy individuals were investigated. Serum free thyroxine and thyreotropine level were determined in all investigated subjects. The systolic-diastolic index (SDI) was measured in all individuals with photopletysmography...
July 2000: Polskie Archiwum Medycyny Wewnętrznej
P Slampa, V Spurný, Z Seneklová, D Krákorová
Orbital radiation therapy appears to be an effective and safe treatment of Graves' ophthalmopathy. Five patients with Graves' ophtalmopathy were treated with external beam radiotherapy during 1996 and 1997 in St. Ann University Hospital. Four of them patients had a past history of hyperthyreoidism, one hypothyreoidism. The radiotherapy was performed with high-energy beam of a linear accelerator. The technique of irradiation employs 2 opposed beams tilted 5 degrees posteriorly. The use of the asymetric jaws is necessary to protect surrounding normal tissues...
August 1998: Vnitr̆ní Lékar̆ství
E Motta, D Rościszewska, W Grzeszczak, W Pokrzywnicki, J Kapustecki, A Kochańska
The serum T3, T4 and TSH concentrations were assessed by RIA method in 25 (14 females, 11 males) long-term treated (mean treatment duration 12.8 years) epileptic patients. The mean serum T3, T4 and TSH levels were lower than in control group according to clinical picture of epilepsy and treatment applied. The lowest mean serum TSH concentration was in patients with known aetiology of epilepsy. Patients with tonic-clonic seizures had lower serum levels of all hormones measured in comparison with the patients with partial seizures...
November 1994: Neurologia i Neurochirurgia Polska
W Geisthövel, B Perschke, R Hehrmann, R Ködding, A von zur Mühlen, H Klein
In 21 males (age 50-78 yrs) without endocrine diseases, plasma thyroxine, triiodothyronine, reverse-triiodothyronine and TSH were determined by specific RIAs in the early stage of an acute myocardial infarction. Blood was taken every 4 hours up to 43 hours after admission. The patients were separated in 2 groups, depending on the severity of the infarction (group A with 11 patients = severe infarction; group B with 10 patients = not severe infarction). 25 healthy men served as an aged-matched control group (age 56-83 yrs)...
November 1980: Zeitschrift Für Kardiologie
K D Bentsen, L Gram, A Veje
Studies investigating the influence of antiepileptic drugs on thyroid hormones usually have compared patients chronically treated with antiepileptic drugs to controls. To date, this type of designs has produced divergent results both with regard to individual drugs and individual thyroid hormones. The present study comprised 31 patients with newly diagnosed epilepsy, commencing treatment with either carbamazepine or valproate. T3, T4, FT4, FT3, rT3, TSH, T3 resin uptake and blood folic acid, were determined before and during antiepileptic monotherapy, thus making the patient his own control...
April 1983: Acta Neurologica Scandinavica
A Scholz
No abstract text is available yet for this article.
May 15, 1973: Klinische Wochenschrift
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