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https://www.readbyqxmd.com/read/28724245/radioactively-hot-particles-detected-in-dusts-and-soils-from-northern-japan-by-combination-of-gamma-spectrometry-autoradiography-and-sem-eds-analysis-and-implications-in-radiation-risk-assessment
#1
Marco Kaltofen, Arnie Gundersen
After the March 11, 2011, nuclear reactor meltdowns at Fukushima Dai-ichi, 180 samples of Japanese particulate matter (dusts and surface soils) and 235 similar U.S. and Canadian samples were collected and analyzed sequentially by gamma spectrometry, autoradiography, and scanning electron microscopy with energy dispersive X-ray analysis. Samples were collected and analyzed over a five-year period, from 2011 to 2016. Detectable levels of (134)Cs and (137)Cs were found in 142 of 180 (80%) Japanese particulate matter samples...
July 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28720764/high-expression-of-abcg2-induced-by-ezh2-disruption-plays-pivotal-roles-in-mds-pathogenesis
#2
Kimihito C Kawabata, Yasutaka Hayashi, Daichi Inoue, Hiroko Meguro, Hiroko Sakurai, Tomofusa Fukuyama, Yosuke Tanaka, Shuhei Asada, Tsuyoshi Fukushima, Reina Nagase, Reina Takeda, Yuka Harada, Jiro Kitaura, Susumu Goyama, Hironori Harada, Hiroyuki Aburatani, Toshio Kitamura
Both proto-oncogenic and tumor-suppressive functions have been reported for EZH2. To investigate the effects of its inactivation, a mutant EZH2 lacking its catalytic domain was prepared (EZH2-dSET). In a mouse bone marrow transplant (BMT) model, EZH2-dSET expression in bone marrow cells (BMCs) induced an MDS-like disease in transplanted mice. Analysis of these mice identified Abcg2 as a direct target of EZH2. Intriguingly, Abcg2 expression alone induced the same disease in the transplanted mice, where stemness genes were enriched...
July 19, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28720472/mantle-cell-lymphoma-involving-the-esophagus-evaluated-by-magnifying-endoscopy-with-narrow-band-imaging
#3
Haruka Toyonaga, Masashi Fukushima, Tetsuro Inokuma, Yukihiro Imai
No abstract text is available yet for this article.
July 15, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28720300/epidemiological-study-of-gastric-helicobacter-spp-in-dogs-with-gastrointestinal-disease-in-japan-and-diversity-of-helicobacter-heilmannii-sensu-stricto
#4
Sanae Kubota-Aizawa, Koichi Ohno, Kenjiro Fukushima, Hideyuki Kanemoto, Ko Nakashima, Kazuyuki Uchida, James K Chambers, Yuko Goto-Koshino, Takayasu Watanabe, Tsutomu Sekizaki, Hitomi Mimuro, Hajime Tsujimoto
Epidemiological and pathological studies of Helicobacter spp. in canine stomachs in Japan were performed to investigate strain specific pathogenicity. Gastric biopsies from 144 dogs with gastrointestinal diseases were evaluated for the presence of Helicobacter spp. using genus and species specific PCRs for Helicobacter felis, Helicobacter bizzozeronii, Helicobacter heilmannii sensu stricto (s.s.) and Helicobacter pylori. PCR indicated that 50/144 (34.7%) dogs were infected with Helicobacter spp. Of the genus positive samples, 21/50 could not be amplified by any of the species specific PCRs...
July 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28717913/survival-benefits-of-surgical-resection-in-patients-with-recurrent-biliary-tract-carcinoma
#5
Hiroaki Motoyama, Akira Kobayashi, Takahide Yokoyama, Akira Shimizu, Noriyuki Kitagawa, Tsuyoshi Notake, Kentaro Fukushima, Hitoshi Masuo, Takahiro Yoshizawa, Shin-Ichi Miyagawa
BACKGROUND: Whether surgical resection for recurrent biliary tract carcinoma (BTC) prolongs survival and the patients who are most likely to benefit from such treatment remain unclear. METHODS: Among 251 patients with recurrences after the initial resection of BTC, a total of 21 patients (8.4%) underwent surgical resection for the recurrence, with a zero mortality rate. The clinicopathological features of these patients were compared with those of patients who did not undergo surgery...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28717074/effect-of-thrombomodulin-alfa-on-disseminated-intravascular-coagulation-in-patients-with-lung-cancer
#6
Kentaro Nakano, Kumiya Sugiyama, Hideyuki Satoh, Hajime Arifuku, Takayoshi Fujimatsu, Naruo Yoshida, Hiroyoshi Watanabe, Shingo Tokita, Tomoshige Wakayama, Masamitsu Tatewaki, Ryosuke Souma, Hiroyuki Masuda, Kenya Koyama, Hirokuni Hirata, Yasutsugu Fukushima
Objective The mortality rate due to disseminated intravascular coagulation (DIC) is higher in patients with lung cancer than in those without. We examined the effect of treatment with thrombomodulin alfa (TM-α) for DIC in lung cancer patients. Methods Subjects were 57 patients with DIC (43 men, 14 women; mean age, 71.7 years), comprising 31 with lung cancer and 26 without. DIC patients with or without lung cancer did not differ significantly in their background characteristics. Results No significant difference was noted in the mortality rate between patients with lung cancer (61...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28716148/prevalence-of-plasma-autoantibody-against-cancer-testis-antigen-ny-eso-1-in-htlv-1-infected-individuals-with-different-clinical-status
#7
Yasuo Shiohama, Tadasuke Naito, Toshio Matsuzaki, Reiko Tanaka, Takeaki Tomoyose, Hiroshi Takashima, Takuya Fukushima, Yuetsu Tanaka, Mineki Saito
BACKGROUND: Detection of specific immune responses against cancer/testis antigen NY-ESO-1 was recently reported in patients with adult T-cell leukemia/lymphoma (ATL) and human T-cell leukemia virus type 1 (HTLV-1)-infected asymptomatic carriers (ACs). However, the relationship of the responses with the HTLV-1 proviral load (PVL) and the levels of viral gene expression remain unclear. FINDINGS: We measured plasma levels of autoantibodies to NY-ESO-1 immunogenic tumor antigen in HTLV-1-infected individuals with different clinical status, and in healthy controls...
July 17, 2017: Virology Journal
https://www.readbyqxmd.com/read/28715950/efficacy-of-the-novel-medical-adhesive-mar-vivo-107-in-an-acute-porcine-liver-resection-model
#8
Hirokazu Tanaka, Kenji Fukushima, Pramod Kadaba Srinivasan, Kerstin Pawlowsky, Babette Koegel, Koichiro Hata, Yonson Ku, Shinji Uemoto, René H Tolba
BACKGROUND: Despite modern surgical techniques, insufficient hemostasis after liver trauma is still a major cause of morbidity and mortality after injury. Therefore, efficient hemostatic agents are indicated. In this study, we evaluated the hemostatic efficacy of a novel synthetic wound adhesive (MAR-VIVO-107) based on polyurethane/polyurea, compared with a widely used fibrin adhesive (Tisseel). MATERIALS AND METHODS: Twelve German Landrace pigs were randomly assigned to 2 groups...
July 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28714955/erratum-acetate-mediated-novel-survival-strategy-against-drought-in-plants
#9
Jong-Myong Kim, Taiko Kim To, Akihiro Matsui, Keitaro Tanoi, Natsuko I Kobayashi, Fumio Matsuda, Yoshiki Habu, Daisuke Ogawa, Takuya Sakamoto, Sachihiro Matsunaga, Khurram Bashir, Sultana Rasheed, Marina Ando, Hiroko Takeda, Kanako Kawaura, Miyako Kusano, Atsushi Fukushima, Endo Takaho A, Takashi Kuromori, Junko Ishida, Taeko Morosawa, Maho Tanaka, Chieko Torii, Yumiko Takebayashi, Hitoshi Sakakibara, Yasunari Ogihara, Kazuki Saito, Kazuo Shinozaki, Alessandra Devoto, Motoaki Seki
This corrects the article DOI: 10.1038/nplants.2017.97.
July 17, 2017: Nature Plants
https://www.readbyqxmd.com/read/28714588/cellular-force-assay-detects-altered-contractility-caused-by-a-nephritis-associated-mutation-in-nonmuscle-myosin-iia
#10
Shota P Fukuda, Tsubasa S Matsui, Takafumi Ichikawa, Taichi Furukawa, Noriyuki Kioka, Shuichiro Fukushima, Shinji Deguchi
Recent progress in understanding the essential roles of mechanical forces in regulating various cellular processes expands the field of biology to one where interdisciplinary approaches with engineering techniques become indispensable. Contractile forces or contractility-inherently present in proliferative cells due to the activity of ubiquitous nonmuscle myosin II (NMII)-are one of such mechano-regulators, but because NMII works downstream of diverse signaling pathways, it is often difficult to predict how the inherent cellular forces change upon perturbations to particular molecules...
July 17, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28714301/assessing-fukushima-derived-radiocesium-in-migratory-pacific-predators
#11
Daniel James Madigan, Zofia Baumann, Owyn E Snodgrass, Heidi Dewar, Michelle Berman-Kowalewski, Kevin C Weng, Jun Nishikawa, Peter H Dutton, Nicholas S Fisher
The 2011 release of Fukushima-derived radionuclides into the Pacific Ocean made migratory sharks, teleosts, and marine mammals a source of speculation and anxiety regarding radiocesium (134+137Cs) contamination, despite a lack of actual radiocesium measurements for these taxa. We measured radiocesium in a diverse suite of large predators from the North Pacific Ocean and report no detectable (i.e., ≥ 0.1 Bq kg-1 dry wt) of Fukushima-derived 134Cs in all samples, except in one olive ridley sea turtle (Lepidochelys olivacea) with trace levels (0...
July 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28711740/early-manifestations-of-epileptic-encephalopathy-brain-atrophy-and-elevation-of-serum-neuron-specific-enolase-in-a-boy-with-beta-propeller-protein-associated-neurodegeneration
#12
Kyoko Takano, Kazuya Goto, Mitsuo Motobayashi, Keiko Wakui, Rie Kawamura, Tomomi Yamaguchi, Yoshimitsu Fukushima, Tomoki Kosho
Mutations in WDR45 are responsible for beta-propeller protein-associated neurodegeneration (BPAN), which is an X-linked form of neurodegeneration with brain iron accumulation. BPAN mainly affects females and is characterized by seizures and developmental delay or intellectual disability until adolescence or early adulthood, followed by severe dystonia, parkinsonism, and progressive dementia. However, rare male patients have recently been reported with hemizygous germline mutations in WDR45 and severe clinical manifestations, such as epileptic encephalopathies...
July 12, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28710475/isotopic-signature-and-nano-texture-of-cesium-rich-micro-particles-release-of-uranium-and-fission-products-from-the-fukushima-daiichi-nuclear-power-plant
#13
Junpei Imoto, Asumi Ochiai, Genki Furuki, Mizuki Suetake, Ryohei Ikehara, Kenji Horie, Mami Takehara, Shinya Yamasaki, Kenji Nanba, Toshihiko Ohnuki, Gareth T W Law, Bernd Grambow, Rodney C Ewing, Satoshi Utsunomiya
Highly radioactive cesium-rich microparticles (CsMPs) released from the Fukushima Daiichi Nuclear Power Plant (FDNPP) provide nano-scale chemical fingerprints of the 2011 tragedy. U, Cs, Ba, Rb, K, and Ca isotopic ratios were determined on three CsMPs (3.79-780 Bq) collected within ~10 km from the FDNPP to determine the CsMPs' origin and mechanism of formation. Apart from crystalline Fe-pollucite, CsFeSi2O6 · nH2O, CsMPs are comprised mainly of Zn-Fe-oxide nanoparticles in a SiO2 glass matrix (up to ~30 wt% of Cs and ~1 wt% of U mainly associated with Zn-Fe-oxide)...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28707383/two-cases-of-early-recurrence-after-transabdominal-preperitoneal-inguinal-hernia-repair
#14
Yoshihisa Yaguchi, Tsuyoshi Inaba, Yoshimasa Kumata, Masahiro Horikawa, Takashi Kiyokawa, Ryoji Fukushima
We performed transabdominal preperitoneal inguinal hernia repair in 46 patients (58 diseases), two of whom experienced early recurrence after mesh repair. Case 1 was a 76-year-old man with a bilateral inguinal hernia (recurrence site, left indirect hernia) after appendectomy. The recurrence occurred 1 month after transabdominal preperitoneal inguinal hernia repair. The mesh was dislocated to the lateral side, and we repaired it using the direct Kugel® patch with an anterior technique. Case 2 was a 79-year-old man with a bilateral inguinal hernia (recurrence site, right direct hernia with an orifice >3 cm) after appendectomy...
July 13, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28705149/f-treegc-a-questionnaire-based-family-tree-creation-software-for-genetic-counseling-and-genome-cohort-studies
#15
Tomoharu Tokutomi, Akimune Fukushima, Kayono Yamamoto, Yasushi Bansho, Tsuyoshi Hachiya, Atsushi Shimizu
BACKGROUND: The Tohoku Medical Megabank project aims to create a next-generation personalized healthcare system by conducting large-scale genome-cohort studies involving three generations of local residents in the areas affected by the Great East Japan Earthquake. We collected medical and genomic information for developing a biobank to be used for this healthcare system. We designed a questionnaire-based pedigree-creation software program named "f-treeGC," which enables even less experienced medical practitioners to accurately and rapidly collect family health history and create pedigree charts...
July 14, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28703875/evaluation-of-bilicare-%C3%A2-transcutaneous-bilirubin-device-in-japanese-newborns
#16
Keiji Yamana, Ichiro Morioka, Daisuke Kurokawa, Sachiyo Fukushima, Kosuke Nishida, Shohei Ohyama, Noriyuki Nishimura, Kandai Nozu, Mariko Taniguchi-Ikeda, Hiroaki Nagase, Kazumichi Fujioka, Sota Iwatani, Hajime Nakamura, Kazumoto Iijima
BACKGROUND: Non-invasive transcutaneous bilirubin (TcB) monitoring has been widely used to screen for hyperbilirubinemia. TcB values measured using the recently developed BiliCare(™) system have not been fully evaluated. METHODS: One hundred and seven TcB measurements were obtained from 82 Japanese newborns ≥ 35 weeks' gestational age within 2 weeks after birth. Measurements were taken at the scaphoid fossa, conchal cavity, and lobe of the ear using BiliCare...
July 13, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28702871/expression-of-podoplanin-in-stromal-fibroblasts-plays-a-pivotal-role-in-the-prognosis-of-patients-with-pancreatic-cancer
#17
Kazuyoshi Hirayama, Hiroshi Kono, Yuuki Nakata, Yoshihiro Akazawa, Hiroyuki Wakana, Hisataka Fukushima, Hideki Fujii
PURPOSE: To investigate the role of podoplanin (PDPN) expression in invasive ductal carcinoma of the pancreas (IDCP) in humans. METHODS: Tumor samples were obtained from 95 patients with IDCP. Immunohistochemical staining was done to evaluate the expression of PDPN in cancer tissues. RESULTS: PDPN was detected predominantly in stromal fibroblasts, stained with α-smooth muscle actin. The cutoff value of PDPN-positive areas was calculated according to a histogram...
July 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/28701890/relationship-between-oxidative-stress-physical-activity-and-vitamin-intake-in-patients-with-asthma
#18
Akira Yamasaki, Yuji Kawasaki, Kenichi Takeda, Tomoya Harada, Yasuyuki Hasegawa, Takehito Fukushima, Ryota Okazaki, Haruhiko Makino, Yoshihiro Funaki, Yuriko Sueda, Akihiro Yamamoto, Jun Kurai, Masanari Watanabe, Eiji Shimizu
BACKGROUND: Oxidative stress plays an important role in the pathogenesis of bronchial asthma. Antioxidant nutrition and supplementation have been used to reduce oxidative stress. However, a clinical trial with antioxidant supplementation showed no beneficial effects in patients with asthma. On the other hand, physical activity is related to the prognosis of chronic obstructive pulmonary disease (COPD) and is also related to oxidant status. We investigated the relationships between oxidative stress, serum levels of vitamins, dietary vitamin intake, daily activities, and pulmonary functions in patients with asthma...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28697277/who-would-be-willing-to-accept-disaster-debris-in-their-backyard-investigating-the-determinants-of-public-attitudes-in-post-fukushima-japan
#19
Naomi Aoki
In the wake of the 2011 Great East Japan Earthquake and tsunami, the Ministry of Environment in Japan asked municipalities nationwide to accept and treat disaster waste. This call for cross-jurisdictional waste treatment provoked considerable public controversy. To explore how the national and municipal governments can seek more public acceptance in the wake of future disasters, this study implemented a nationwide survey and addressed the question of what factors influence the public's willingness to support their municipalities' plans to host disaster waste...
July 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28692938/radioactive-impacts-on-nekton-species-in-the-northwest-pacific-and-humans-more-than-one-year-after-the-fukushima-nuclear-accident
#20
Wu Men, Fangfang Deng, Jianhua He, Wen Yu, Fenfen Wang, Yiliang Li, Feng Lin, Jing Lin, Longshan Lin, Yusheng Zhang, Xingguang Yu
This study investigated the radioactive impacts on 10 nekton species in the Northwest Pacific more than one year after the Fukushima Nuclear Accident (FNA) from the two perspectives of contamination and harm. Squids were especially used for the spatial and temporal comparisons to demonstrate the impacts from the FNA. The radiation doses to nekton species and humans were assessed to link this radioactivity contamination to possible harm. The total dose rates to nektons were lower than the ERICA ecosystem screening benchmark of 10μGy/h...
July 7, 2017: Ecotoxicology and Environmental Safety
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