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https://www.readbyqxmd.com/read/28317684/comparison-of-the-performance-and-safety-of-2-ophthalmic-viscosurgical-devices-in-cataract-surgery
#1
Gerd U Auffarth, Florian N Auerbach, Tanja Rabsilber, José A Gegúndez, Ricardo Cuiña, Yves Renard, Paolo Vinciguerra, Fabrizio Camesasca, Francoise Van Cauwenberge, Thierry Amzallag, Gysbert Van Setten, Mike P Holzer
PURPOSE: To compare the clinical performance and safety of 2 ophthalmic viscosurgical devices (OVDs)-Twinvisc (OVD 1) and Duovisc (OVD 2)-in cataract surgery. SETTING: European multicenter study. DESIGN: Prospective randomized controlled study. METHODS: Patients with cataract had phacoemulsification and intraocular lens implantation in 1 eye. They were randomly assigned to receive OVD 1 or OVD 2. Preoperative and postoperative examinations over 3 months included mean intraocular pressure (IOP), incidence of IOP peaks (≥30 mm Hg and ≥24 mm Hg), endothelial cell count (ECC), corneal thickness, and intraocular inflammation...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28317673/effect-of-balanced-phacoemulsification-tip-on-the-outcomes-of-torsional-phacoemulsification-using-an-active-fluidics%C3%A2-system
#2
Sudarshan Khokhar, Neelima Aron, Sagnik Sen, Ganesh Pillay, Esha Agarwal
PURPOSE: To compare the outcomes of torsional phacoemulsification with a new balanced tip (Intrepid) and a conventional tip (Kelman) using a single active-fluidics torsional phacoemulsification machine (Centurion). SETTING: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. DESIGN: Prospective comparative case-control study. METHODS: Patients with senile cataract had torsional phacoemulsification with the Kelman conventional tip or the new Intrepid balanced tip using the active-fluidics torsional machine...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28317665/preparation-of-ultrathin-grafts-for-descemet-stripping-endothelial-keratoplasty-with-a-single-microkeratome%C3%A2-pass
#3
Vito Romano, Bernhard Steger, Jayavani Myneni, Mark Batterbury, Colin E Willoughby, Stephen B Kaye
We present a technique to achieve ultrathin Descemet-stripping automated endothelial keratoplasty (DSAEK). Using a simple method of controlling artificial anterior chamber pressure and drying the corneal surface, it was possible to thin the donor cornea at a rate of 11 μm a minute. When the donor cornea was between 500 μm and 510 μm, a single pass was made using a 350 μm microkeratome head followed by a peripheral dissection. The resulting mean graft thickness was 83.2 μm ± 14.9 (SD) (range 50 to 98 μm) with a mean peripheral graft edge thickness of 106...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28306601/assessing-the-impact-of-diabetes-mellitus-on-donor-corneal-endothelial-cell-density
#4
Chase A Liaboe, Benjamin T Aldrich, Pamela C Carter, Jessica M Skeie, Kimberlee A Burckart, Gregory A Schmidt, Cynthia R Reed, M Bridget Zimmerman, Mark A Greiner
PURPOSE: To quantify changes in endothelial cell density (ECD) of donor corneal tissue in relation to the presence or absence of a medical history of diabetes mellitus diagnosis, treatment, and complications. METHODS: A retrospective review was performed for all corneas collected at Iowa Lions Eye Bank between January 2012 and December 2015. For purposes of analysis, donor corneas were divided into 4 groups: nondiabetic, non-insulin-dependent diabetic, insulin-dependent diabetic without medical complications due to diabetes, and insulin-dependent diabetic with medical complications due to diabetes...
March 16, 2017: Cornea
https://www.readbyqxmd.com/read/28303370/comparison-of-graft-survival-following-penetrating-keratoplasty-and-descemet-s-stripping-endothelial-keratoplasty-in-eyes-with-a-glaucoma-drainage-device
#5
Shawn M Iverson, Oriel Spierer, George C Papachristou, William J Feuer, Wei Shi, David S Greenfield, Terrence P O'Brien
PURPOSE: To compare corneal graft survival rates after penetrating keratoplasty (PK) and Descemet's stripping endothelial keratoplasty (DSEK) in patients with a glaucoma drainage device (GDD) or medically managed glaucoma. METHODS: A retrospective chart review was conducted on consecutive patients who underwent primary PK or primary DSEK. Inclusion criteria consisted of eyes with a diagnosis of glaucoma prior to corneal transplantation and a minimum of 6 months of follow-up...
March 16, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28300735/comparison-of-femtosecond-laser-assisted-descemetic-and-predescemetic-lamellar-keratoplasty-for-keratoconus
#6
Yan Lu, Ana Beatriz Diniz Grisolia, Yi-Rui Ge, Chun-Yan Xue, Qian Cao, Li-Ping Yang, Zhen-Ping Huang
PURPOSE: The purpose of this study is to compare the outcomes following femtosecond laser-assisted deep anterior lamellar keratoplasty (DALK) with 75% of stromal dissection (predescemetic group) and femtosecond laser-assisted DALK using big-bubble technique with total stromal resection (descemetic group) for the treatment of keratoconus. SUBJECTS AND METHODS: Twenty eyes of 17 patients with keratoconus were studied. There were 10 eyes of 9 patients in predescemetic group and 10 eyes of 8 patients in descemetic group...
January 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28297042/combination-surgery-with-transcorneal-microincision-vitrectomy-surgery-and-intrascleral-intraocular-lens-fixation-for-spontaneous-intraocular-lens-luxation
#7
Kenichi Kohzaki, Hisato Gunji, Hiroshi Tsuneoka
To present a combination technique for two cases of in-the-bag intraocular lens (IOL) luxation into the vitreous cavity. Vitrectomy was performed via a cornea microincision vitrectomy system, and the luxated IOL was fixed into the sclera. IOL fixation is simple from no trocar cannulas and less disrupted conjunctiva. Postoperative corneal endothelial cell density in Case 1 and Case 2 were reduced by -2.1% and -5.1%, respectively. Postoperative frequency of hexagon was decreased in Case 1 but maintained in Case 2...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28292776/comparison-of-corneal-endothelial-cell-density-and-morphology-after-posterior-chamber-phakic-intraocular-lens-implantation-with-and-without-a-central-hole
#8
Hiroyasu Goukon, Kazutaka Kamiya, Kimiya Shimizu, Akihito Igarashi
AIM: To compare the corneal endothelial cells after posterior chamber phakic intraocular lens with and without a central hole (hole implantable collamer lens (ICL) and conventional ICL) implantation for the correction of moderate to high myopia. METHODS: This retrospective study evaluated 34 eyes of 34 patients who underwent hole ICL implantation and 25 eyes of 25 patients who underwent conventional ICL implantation. Preoperatively and 3 months, and 1 and 2 years postoperatively, we compared the central corneal endothelial cell density (ECD), coefficient of variation in cell size (CV) and the percentage of hexagonal cells (HEX) between the two groups using a non-contact specular microscope (EM-3000, Tomey)...
March 14, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28288590/iridoschisis-a-case-report-and-literature-review
#9
Yiyi Chen, Yiyong Qian, Peirong Lu
BACKGROUND: Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we speculate that the scope of iridoschisis has a rare association with intraocular pressure and the loss of corneal endothelial cells after surgery, which is mainly due to the surgery and not iridocorneal mechanical contact...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28283279/randomized-controlled-trial-comparing-transepithelial-corneal-cross-linking-using-iontophoresis-with-the-dresden-protocol-in-progressive-keratoconus
#10
Marco Lombardo, Daniela Giannini, Giuseppe Lombardo, Sebastiano Serrao
PURPOSE: To compare clinical outcomes of transepithelial corneal cross-linking using iontophoresis (T-ionto CL) and standard corneal cross-linking (standard CL) for the treatment of progressive keratoconus 12 months after the operation. DESIGN: Prospective randomized controlled clinical trial. PARTICIPANTS: Thirty-four eyes of 25 participants with progressive keratoconus were randomized into T-ionto CL (22 eyes) or standard CL (12 eyes). METHODS: T-ionto CL was performed using an iontophoresis device with dextran-free 0...
March 7, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28282692/anterior-and-posterior-lamellar-graft-on-the-same-eye-to-treat-fuchs-endothelial-corneal-dystrophy-the-corneal-sandwich-graft
#11
S Hardy, I Guber, L Franscini, F Majo
No abstract text is available yet for this article.
March 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28282413/glaucoma-associated-with-iridocorneal-endothelial-syndrome-in-203-indian-subjects
#12
Premanand Chandran, Harsha L Rao, Anil K Mandal, Nikhil S Choudhari, Chandra S Garudadri, Sirisha Senthil
PURPOSE: To report the demographic profile, clinical features, and prevalence of glaucoma and its management in patients with Iridocorneal endothelial (ICE) syndrome. METHODS: Retrospective review of 203 consecutive subjects with ICE syndrome at a tertiary eye care centre between January 1988 and June 2013. RESULTS: ICE syndrome was present in 223 eyes of 203 subjects, 124 (61%) were female and 79 (39%) were male. The median age at presentation was 43 years (1st (Q1) and 3rd (Q3) quartile; 34, 51 years)...
2017: PloS One
https://www.readbyqxmd.com/read/28280298/corneal-endothelium-and-central-corneal-thickness-changes-in-type-2-diabetes-mellitus
#13
Amira El-Agamy, Shams Alsubaie
PURPOSE: This study was conducted to compare the corneal endothelial cell density (ECD), morphological features, and central corneal thickness (CCT) in type 2 diabetes mellitus (DM) with age-matched, nondiabetic control subjects using EM-3000 Specular Microscope. STUDY DESIGN: This was a prospective, hospital-based, nonrandomized, case-control, observational, and quantitative study. SUBJECTS AND METHODS: The study included 57 patients (57 eyes) with type 2 DM and 45 control (nondiabetic) subjects (45 eyes)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28273942/human-corneal-endothelial-cell-cultivation-from-old-donor-corneas-with-forced-attachment
#14
Mohit Parekh, Sajjad Ahmad, Alessandro Ruzza, Stefano Ferrari
Human corneal endothelial cells (HCEnCs) are responsible for maintaining the transparency of the cornea. Damaged or diseased HCEnCs may cause blindness. Replacement of the diseased cells with a healthy donor endothelium is the only currently available treatment. Tissue-engineering can serve as an alternative to conventional donor corneal transplantation. Due to the global shortage of donor corneas, a wide interest in the development of cultured graft substitutes and artificial corneas has increased. Availability of the old donor corneas is higher especially for research...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28271619/reduced-anterior-chamber-contamination-by-frequent-surface-irrigation-with-diluted-iodine-solutions-during-cataract-surgery
#15
Hiroyuki Shimada, Shinji Arai, Hiroyuki Nakashizuka, Takayuki Hattori, Mitsuko Yuzawa
PURPOSE: To verify that ocular surface irrigation with 0.025% povidone-iodine (PI) or 0.0025% polyvinyl alcohol-iodine (PAI) during cataract surgery minimizes bacterial contamination of the anterior chamber. METHODS: The study was a prospective, interventional case series. First, the bactericidal effect of PI or PAI against Staphylococcus aureus was evaluated in vitro. Next, in 400 eyes undergoing cataract surgery, the ocular surface was irrigated every 20 seconds during surgery with balanced salt solution (BSS; 200 eyes) or BSS containing 0...
March 8, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28271013/ultrahigh-resolution-oct-imaging-of-the-human-cornea
#16
René M Werkmeister, Sabina Sapeta, Doreen Schmidl, Gerhard Garhöfer, Gerald Schmidinger, Valentin Aranha Dos Santos, Gerold C Aschinger, Isabella Baumgartner, Niklas Pircher, Florian Schwarzhans, Anca Pantalon, Harminder Dua, Leopold Schmetterer
We present imaging of corneal pathologies using optical coherence tomography (OCT) with high resolution. To this end, an ultrahigh-resolution spectral domain OCT (UHR-OCT) system based on a broad bandwidth Ti:sapphire laser is employed. With a central wavelength of 800 nm, the imaging device allows to acquire OCT data at the central, paracentral and peripheral cornea as well as the limbal region with 1.2 µm x 20 µm (axial x lateral) resolution at a rate of 140 000 A-scans/s. Structures of the anterior segment of the eye, not accessible with commercial OCT systems, are visualized...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28268563/automated-morphometric-description-of-human-corneal-endothelium-from-in-vivo-specular-and-confocal-microscopy
#17
F Scarpa, A Ruggeri
Corneal images acquired by in-vivo specular and confocal microscopy provide clinical information on the cornea endothelium health state. Indeed, the normal hexagonal shape of endothelial cells is usually affected by age and pathologies. At present, the analysis is based on manual or semi-automatic methods and the segmentation of a large number of endothelial cells is required for a meaningful estimation of the clinical parameters. We propose an automated method that detects the centers of endothelial cells by convolving the original image with customized two-dimensional kernels, derives a structure made by connected vertices from the recognized centers using the Euclidean distance, and fine-tunes the derived structure through a genetic algorithm, which combines information about the typical regularity of endothelial cells shape with the pixels intensity of the actual image...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263034/analysis-of-the-learning-curve-for-pre-cut-corneal-specimens-in-preparation-for-lamellar-transplantation-a-prospective-single-centre-consecutive-case-series-prepared-at-the-lions-new-south-wales-nsw-eye-bank
#18
Aifric Isabel Martin, Rajnesh Devasahayam, Christopher Hodge, Simon Cooper, Gerard L Sutton
IMPORTANCE: This study represents the first paper to establish a learning curve by a single technician. BACKGROUND: Preparation of pre-cut corneal endothelial grafts commenced at Lions New South Wales Eye Bank in December 2014. The primary objective of this study was to review the safety and reliability of the preparation method during the first year of production. DESIGN: Hospital-based, prospective case series PARTICIPANTS: 234 consecutive donor corneal lenticules METHODS: Donor lenticules were prepared by a single operator using a linear cutting microkeratome...
March 6, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28260988/human-corneal-endothelial-cells-expanded-in-vitro-are-a-powerful-resource-for-tissue-engineering
#19
REVIEW
Yongsong Liu, Hong Sun, Min Hu, Min Zhu, Sean Tighe, Shuangling Chen, Yuan Zhang, Chenwei Su, Subo Cai, Ping Guo
Human corneal endothelial cells have two major functions: barrier function mediated by proteins such as ZO-1 and pump function mediated by Na-K-ATPase which help to maintain visual function. However, human corneal endothelial cells are notorious for their limited proliferative capability in vivo and are therefore prone to corneal endothelial dysfunction that eventually may lead to blindness. At present, the only method to cure corneal endothelial dysfunction is by transplantation of a cadaver donor cornea with normal corneal endothelial cells...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28260451/descemet-stripping-automated-endothelial-keratoplasty-our-experience-at-king-hussein-medical-center
#20
Amal Al-Thawabi, Wafa Asfour, Mousa Al-Madani
OBJECTIVES: In this study, we report our experience at King Hussein Medical Center with Descemet stripping automated endothelial keratoplasty. MATERIALS AND METHODS: This study was conducted at King Hussein Medical Center of the Royal Medical Services during the period between January 2015 and January 2016. Patients who underwent Descemet stripping automated endothelial keratoplasty were enrolled in the study. We performed a comprehensive overview of the advantages of the surgery and analyzed the donor tissue selection criteria, indications, detailed surgical techniques of the procedure, and surgical outcomes...
February 2017: Experimental and Clinical Transplantation
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