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https://www.readbyqxmd.com/read/28935004/intestinal-parasites-and-anthelmintic-treatments-in-a-laboratory-colony-of-wild-caught-african-pouched-rats-cricetomys-ansorgei
#1
Cassandra O Cullin, Matthew S Sellers, Erin R Rogers, Kathleen E Scott, Danielle N Lee, Alexander G Ophir, Todd A Jackson
African giant pouched rats (Cricetomys spp.) are large rodents native to subSaharan Africa. Wild-caught pouched rats identified as Cricetomys ansorgei (n = 49) were imported from Tanzania. A survey of gastrointestinal parasitism by fecal flotation revealed the presence of multiple parasites, including Nippostrongylus spp., Heterakis spp., Trichuris spp., Hymenolepis spp., Raillietina spp., and Eimeria spp. Oral self-administered fenbendazole (150 ppm), topical moxidectin (2 mg/kg), pyrantel pamoate (15 mg/kg), piperazine (100 mg/kg daily), and injectable ivermectin (0...
October 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28934299/a-novel-copro-diagnostic-molecular-method-for-qualitative-detection-and-identification-of-parasitic-nematodes-in-amphibians-and-reptiles
#2
Lucas G Huggins, Christopher J Michaels, Sheena M Cruickshank, Richard F Preziosi, Kathryn J Else
Anthropogenic disturbance via resource acquisition, habitat fragmentation and climate change, amongst other factors, has led to catastrophic global biodiversity losses and species extinctions at an accelerating rate. Amphibians are currently one of the worst affected classes with at least a third of species categorised as being threatened with extinction. At the same time, they are also critically important for many habitats and provide man with a powerful proxy for ecosystem health by acting as a bioindicator group...
2017: PloS One
https://www.readbyqxmd.com/read/28924616/soil-transmitted-helminth-infections-are-not-associated-with-compromised-antibody-responses-to-previously-administered-measles-and-tetanus-vaccines-among-hiv-1-infected-art-na%C3%A3-ve-kenyan-adults
#3
Helen L Storey, Benson Singa, Jackie Naulikha, Helen Horton, Barbra A Richardson, Grace John-Stewart, Judd L Walson
In many regions of sub-Saharan Africa, both HIV and helminth infections are prevalent. HIV-1 (human immunodeficiency virus type 1) and helminth infections can both compromise immune responses in humans. To determine whether the presence of helminth infection or the treatment of helminth infection alters unstimulated vaccine responses among HIV-1 infected individuals, we conducted two nested serologic studies. Blood samples were collected for HIV disease monitoring and vaccine-specific serologic assays, while stool was evaluated by direct microscopy methods...
February 2017: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/28912965/medically-important-parasites-carried-by-cockroaches-in-melong-subdivision-littoral-cameroon
#4
R J Atiokeng Tatang, H G Tsila, J Wabo Poné
Cockroaches have been recognized as mechanical vectors of pathogens that can infest humans or animals. A total of 844 adult cockroaches (436 males and 408 females) were caught. In the laboratory, cockroaches were first washed in saturated salt solution to remove ectoparasites and then rinsed with 70% alcohol, dried, and dissected for endoparasites. An overall transport rate of 47.39% was recorded. Six genera of parasites were identified. These were Ascaris (33.76%), Trichuris (11.97%), Capillaria (6.16%), Toxocara (4...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28905715/pilot-study-to-assess-the-efficacy-of-ivermectin-and-fenbendazole-for-treating-captive-born-olive-baboons-papio-anubis-coinfected-with-strongyloides-f%C3%A3-lleborni-and-trichuris-trichiura
#5
Mason V Reichard, Jennifer E Thomas, Maria Chavez-Suarez, Cassandra O Cullin, Gary L White, Emily C Wydysh, Roman F Wolf
In this study, we evaluated the efficacy of combined treatment with ivermectin and fenbendazole (IVM-FBZ) for treating captive olive baboons (Papio anubis) infected with Strongyloides fülleborni and Trichuris trichiura, 2 common nematode parasites of these NHP. Infected baboons were treated for a total of 9 wk with ivermectin (400 μg/kg IM twice weekly) and fenbendazole (50 mg/kg PO once daily for 3 d; 3 rounds of treatment, 21 d apart). Five baboons naturally infected with both S. fülleborni and T. trichiura (n = 4) or S...
January 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28884022/identification-characterization-and-structure-of-tm16-from-trichuris-muris
#6
Zhuyun Liu, Alan Kelleher, Shanii Tabb, Junfei Wei, Jeroen Pollet, Peter J Hotez, Maria Elena Bottazzi, Bin Zhan, Oluwatoyin A Asojo
Trichuriasis is a disease of poverty for which excretory and secretory (ES) products that induce the protective immunity are being investigated as candidate vaccines antigens. In this study, ES products of T. muris and immune sera were produced. The immune sera recognized more than 20 proteins on a 2D-gel of ES products of T. muris adult worms. Tm16 was one of the proteins identified by mass spectrometry. Tm16 shares 57% sequence identity with Ov16, an immunodominant diagnostic antigen from Onchocerca volvulus...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28882382/soil-transmitted-helminth-infections
#7
REVIEW
Peter Mark Jourdan, Poppy H L Lamberton, Alan Fenwick, David G Addiss
More than a quarter of the world's population is at risk of infection with the soil-transmitted helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator americanus), Trichuris trichiura, and Strongyloides stercoralis. Infected children and adults present with a range of medical and surgical conditions, and clinicians should consider the possibility of infection in individuals living in, or returning from, endemic regions. Although safe and effective drugs are donated free to endemic countries, only half of at-risk children received treatment in 2016...
September 4, 2017: Lancet
https://www.readbyqxmd.com/read/28866987/helminth-composition-and-prevalence-of-indigenous-and-invasive-synanthropic-murid-rodents-in-urban-areas-of-gauteng-province-south-africa
#8
R S Julius, E V Schwan, C T Chimimba
Although synanthropic rodents such as the indigenous species, Mastomys coucha, and the invasive species, Rattus norvegicus, R. rattus and R. tanezumi, are well-known to be hosts to various micro- and macroparasites, their helminth parasite fauna is poorly studied in South Africa. In an attempt to remedy the situation, the aim of the present study was to investigate the helminth fauna of these sympatric rodent species, which were obtained from the informal settlements of Alexandra, Tembisa, Diepsloot and residential suburbs of Pretoria and Hammanskraal, Gauteng Province, South Africa...
September 4, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28866984/transmission-of-opisthorchis-viverrini-schistosoma-mekongi-and-soil-transmitted-helminthes-on-the-mekong-islands-southern-lao-pdr
#9
Youthanavanh Vonghachack, Peter Odermatt, Keoka Taisayyavong, Souphanh Phounsavath, Kongsap Akkhavong, Somphou Sayasone
BACKGROUND: Prevalence of Opisthorchis viverrini, Schistosoma mekongi and soil-transmitted helminths (STH) remains high in Lao People's Democratic Republic (Lao PDR), despite control efforts including mass-drug administration, education and communication campaigns. New approaches are required to advance helminth control. METHODS: An ecohealth study was conducted on two Mekong islands in Southern Laos. Demographic and behavioural data were collected by questionnaire...
September 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28864027/efficacy-and-safety-of-tribendimidine-tribendimidine-plus-ivermectin-tribendimidine-plus-oxantel-pamoate-and-albendazole-plus-oxantel-pamoate-against-hookworm-and-concomitant-soil-transmitted-helminth-infections-in-tanzania-and-c%C3%A3-te-d-ivoire-a-randomised-controlled
#10
Wendelin Moser, Jean T Coulibaly, Said M Ali, Shaali M Ame, Amour K Amour, Richard B Yapi, Marco Albonico, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser
BACKGROUND: Preventive chemotherapy is the current strategy to control soil-transmitted helminth infections (caused by Ascaris lumbricoides, hookworm, and Trichuris trichiura). But, to improve efficacy and avoid emerging resistance, new drugs are warranted. Tribendimidine has shown good anthelmintic efficacy and is therefore a frontrunner for monotherapy and combination chemotherapy. METHODS: We did a randomised, controlled, single-blinded, non-inferiority trial on Pemba Island, Tanzania, and in Côte d'Ivoire...
August 29, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28838305/point-of-care-mobile-digital-microscopy-and-deep-learning-for-the-detection-of-soil-transmitted-helminths-and-schistosoma-haematobium
#11
Oscar Holmström, Nina Linder, Billy Ngasala, Andreas Mårtensson, Ewert Linder, Mikael Lundin, Hannu Moilanen, Antti Suutala, Vinod Diwan, Johan Lundin
BACKGROUND: Microscopy remains the gold standard in the diagnosis of neglected tropical diseases. As resource limited, rural areas often lack laboratory equipment and trained personnel, new diagnostic techniques are needed. Low-cost, point-of-care imaging devices show potential in the diagnosis of these diseases. Novel, digital image analysis algorithms can be utilized to automate sample analysis. OBJECTIVE: Evaluation of the imaging performance of a miniature digital microscopy scanner for the diagnosis of soil-transmitted helminths and Schistosoma haematobium, and training of a deep learning-based image analysis algorithm for automated detection of soil-transmitted helminths in the captured images...
June 2017: Global Health Action
https://www.readbyqxmd.com/read/28831216/noninvasive-assessment-of-gastrointestinal-parasites-infection-in-free-ranging-wild-herbivores-and-adjoining-livestock-of-panna-tiger-reserve-madhya-pradesh-india
#12
Abhay Sengar, A B Shrivastav, K P Singh, Amol Rokde
AIM: This study was conducted to know the epidemiology of gastrointestinal parasites of free-ranging wild herbivores and adjoining livestock of Panna Tiger Reserve, Madhya Pradesh, India. MATERIALS AND METHODS: A total of 374 fecal samples from wild herbivores (Chital Axis axis - 123, Sambar Rusa unicolor - 94, Nilgai Boselaphus tragocamelus - 86, and Chinkara Gazella bennettii - 71) and 284 fecal samples of domestic herbivores (cattle - 118, buffalo - 78, and goat - 88) were collected from common grazing land and adjoining area of tiger reserve...
July 2017: Veterinary World
https://www.readbyqxmd.com/read/28819509/prevalence-and-intensity-of-soil-transmitted-helminths-among-school-children-of-mendera-elementary-school-jimma-southwest-ethiopia
#13
Ephrem Tefera, Tariku Belay, Seleshi Kebede Mekonnen, Ahmed Zeynudin, Tefera Belachew
INTRODUCTION: Soil transmitted helminths are wide spread in developing countries and in Ethiopia the prevalence of STHs varies in different parts of the country. The aim of this study was to determine the prevalence and intensity of soil transmitted helminths among school children of Mendera Elementary School Jimma town, Southwestern Ethiopia. METHODS: A cross-sectional study was conducted between March 29 and April 9, 2010 to determine the prevalence and intensity of soil transmitted helminths among elementary school children...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28802050/distinct-dc-subsets-regulate-adaptive-th1-and-2-responses-during-trichuris-muris-infection
#14
M Demiri, K Müller-Luda, W W Agace, M Svensson-Frej
Low- and high-dose infections with the murine large intestinal nematode Trichuris muris are associated with induction of adaptive Th1 and Th2 responses, respectively, in mesenteric lymph nodes (MLN). Classical dendritic cells (cDC) accumulate in the large intestinal mucosa and MLN upon T. muris infection, yet their role in driving adaptive responses to infection remains largely unknown. We performed low- and high-dose T. muris infections of mice deficient in defined cDC subsets to investigate their role in induction of adaptive immune responses...
August 12, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28797540/efficiency-of-two-sewage-treatment-systems-activated-sludge-and-natural-lagoons-for-helminth-egg-removal-in-morocco
#15
Sana Chaoua, Samia Boussaa, Ahmed Khadra, Ali Boumezzough
Morocco is a country known for its vulnerability of water resources because of its arid and semi-arid climate. Thus, recycled wastewater has been suggested for agricultural activities, but contamination of these wastewaters is a major concern. The current study aims to determine the occurrence of helminth eggs in urban wastewater and to evaluate the removal of these pathogens by two sewage treatment systems: activated sludge and natural lagoons. The samples of wastewater and sludge were collected from two wastewater treatment plants (WWTP) located in Marrakech and Chichaoua, Morocco...
August 7, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28793922/comparison-of-novel-and-standard-diagnostic-tools-for-the-detection-of-schistosoma-mekongi-infection-in-lao-people-s-democratic-republic-and-cambodia
#16
Youthanavanh Vonghachack, Somphou Sayasone, Virak Khieu, Robert Bergquist, Govert J van Dam, Pytsje T Hoekstra, Paul L A M Corstjens, Beatrice Nickel, Hanspeter Marti, Jürg Utzinger, Sinuon Muth, Peter Odermatt
BACKGROUND: Given the restricted distribution of Schistosoma mekongi in one province in Lao People's Democratic Republic (Lao PDR) and two provinces in Cambodia, together with progress of the national control programmes aimed at reducing morbidity and infection prevalence, the elimination of schistosomiasis mekongi seems feasible. However, sensitive diagnostic tools will be required to determine whether elimination has been achieved. We compared several standard and novel diagnostic tools in S...
August 10, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28761488/intestinal-helminths-in-different-species-of-rodents-in-north-khorasan-province-northeast-of-iran
#17
Kourosh Arzamani, Mitra Salehi, Iraj Mobedi, Amir Adinezade, Hamid Hasanpour, Mohammad Alavinia, Jamshid Darvish, Mohammad Reza Shirzadi, Zeinolabedin Mohammadi
BACKGROUND: Rodents are an important source of zoonotic diseases for human. The aim of this study was to determine the infectivity of rodents with intestinal helminths in North Khorasan Province, Iran. METHODS: One hundred and thirteen rodents were collected using different collection methods such as kill and live traps, digging of their burrow, filling of their hiding places with water and hand net during 2011-2013. Their alimentary canals were removed in the laboratory and helminths were determined in the department of parasitology, Tehran University of Medical Sciences...
April 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28761475/the-helminths-causing-surgical-or-endoscopic-abdominal-intervention-a-review-article
#18
REVIEW
Erdal Uysal, Mehmet Dokur
BACKGROUND: Helminths sometimes require surgical or endoscopic intervention. Helminths may cause acute abdomen, mechanical intestinal obstruction, gastrointestinal hemorrhage, perforation, hepatitis, pancreatitis, and appendicitis. This study aimed to determine the surgical diseases that helminths cause and to gather, analyze the case reports, case series and original articles about this topic in literature. METHODS: This study was designed as a retrospective observational study...
April 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28749758/identifying-helminth-infections-via-routine-fecal-parasitological-examinations-in-korea
#19
Seung Ho Choi, Changhyun Lee, Jong In Yang, Min-Sun Kwak, Goh Eun Chung, Hae Yeon Kang, Su Jin Chung, Jeong Yoon Yim, Joo Sung Kim
We conducted this study to explore the extent of occult helminth infection identified by fecal parasitological examinations or organ-specific examinations such as colonoscopy and abdominal ultrasonography (US) during health checkups. We analyzed 197,422 fecal samples from 99,451 subjects who received health checkups at a single center over 10 years. We found that 3,472 (1.8%) samples from 3,342 (3.4%) subjects tested positive for parasitic ova, including clonorchiasis, metagonimiasis, trichuriasis, ascariasis, trichostrongylosis, taeniasis, and enterobiasis...
July 24, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28747239/palaeoparasitology-and-palaeogenetics-review-and-perspectives-for-the-study-of-ancient-human-parasites
#20
Nathalie M-L Côté, Matthieu LE Bailly
While some species of parasites can be identified to species level from archaeological remains using microscopy (i.e. Enterobius vermicularis, Clonorchis sinensis), others can only be identified to family or genus level as different species produce eggs with similar morphology (i.e. Tænia sp. and Echinococcus sp.). Molecular and immunological approaches offer the possibility to provide more precise determination at the species level. They can also identify taxa when classic parasite markers such as eggs or cysts have been destroyed over time...
July 27, 2017: Parasitology
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