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https://www.readbyqxmd.com/read/27908696/erratum-to-molecular-approach-to-detect-albendazole-resistance-in-trichuris-trichiura-among-orang-asli-in-malaysia-international-journal-of-infectious-diseases-volume-45-supplement-1-april-2016-page-369
#1
Mehru Nisha, Verasingam Kumarasamy, Stephen Ambu, Fabian Davamani, Mak Joon Wah
No abstract text is available yet for this article.
November 28, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27905107/co-operative-suppression-of-inflammatory-responses-in-human-dendritic-cells-by-plant-proanthocyanidins-and-products-from-the-parasitic-nematode-trichuris-suis
#2
Andrew R Williams, Elsenoor J Klaver, Lisa C Laan, Aina Ramsay, Christos Fryganas, Rolf Difborg, Helene Kringel, Jess D Reed, Irene Mueller-Harvey, Søren Skov, Irma van Die, Stig M Thamsborg
Interactions between dendritic cells (DCs) and environmental, dietary and pathogen antigens play a key role in immune homeostasis and regulation of inflammation. Dietary polyphenols such as proanthocyanidins (PAC) may reduce inflammation, and we therefore hypothesized that PAC may suppress lipopolysaccharide (LPS) -induced responses in human DCs and subsequent T helper type 1 (Th1) -type responses in naive T cells. Moreover, we proposed that, because DCs are likely to be exposed to multiple stimuli, the activity of PAC may synergise with other bioactive molecules that have anti-inflammatory activity, e...
November 7, 2016: Immunology
https://www.readbyqxmd.com/read/27903301/high-prevalence-of-strongyloides-stercoralis-in-school-aged-children-in-a-rural-highland-of-north-western-ethiopia-the-role-of-intensive-diagnostic-work-up
#3
Aranzazu Amor, Esperanza Rodriguez, José M Saugar, Ana Arroyo, Beatriz López-Quintana, Bayeh Abera, Mulat Yimer, Endalew Yizengaw, Derejew Zewdie, Zimman Ayehubizu, Tadesse Hailu, Wondemagegn Mulu, Adriana Echazú, Alejandro J Krolewieki, Pilar Aparicio, Zaida Herrador, Melaku Anegagrie, Agustín Benito
BACKGROUND: Soil-transmitted helminthiases (hookworms, Ascaris lumbricoides and Trichuris trichiura) are extremely prevalent in school-aged children living in poor sanitary conditions. Recent epidemiological data suggest that Strongyloides stercoralis is highly unreported. However, accurate data are essential for conducting interventions aimed at introducing control and elimination programmes. METHODS: We conducted a cross-sectional survey of 396 randomly selected school-aged children in Amhara region in rural area in north-western Ethiopia, to assess the prevalence of S...
December 1, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27891580/acute-infection-with-the-intestinal-parasite-trichuris-muris-has-long-term-consequences-on-mucosal-mast-cell-homeostasis-and-epithelial-integrity
#4
Daniel Sorobetea, Jacob Bak Holm, Henrietta Henningsson, Karsten Kristiansen, Marcus Svensson-Frej
A hallmark of parasite infection is the accumulation of innate immune cells, notably granulocytes and mast cells, at the site of infection. While this is typically viewed as a transient response, with the tissue returning to steady state once the infection is cleared, we found that mast cells accumulated in the large-intestinal epithelium following infection with the nematode Trichuris muris and persisted at this site for several months after worm expulsion. Mast cell accumulation in the epithelium was associated with the induction of type-2 immunity and appeared to be driven by increased maturation of local progenitors in the intestinal lamina propria...
November 28, 2016: European Journal of Immunology
https://www.readbyqxmd.com/read/27888125/initiating-ntd-programs-targeting-schistosomiasis-and-soil-transmitted-helminthiasis-in-two-provinces-of-the-democratic-republic-of-the-congo-establishment-of-baseline-prevalence-for-mass-drug-administration
#5
Achille Kabore, Moudachirou Ibikounle, Jean Jacques Tougoue, Sylvain Mupoyi, Martin Ndombe, Scott Shannon, Eric A Ottesen, Faustin Mukunda, Naomi Awaca
BACKGROUND: Schistosomiasis (SCH) and soil-transmitted helminthiasis (STH) are widely distributed in the Democratic Republic of the Congo (DRC) and constitute a serious public health problem. As recommended by the World Health Organization (WHO), before launching mass chemotherapy to control these diseases, parasitological surveys were conducted in sentinel sites in six health zones (HZs) in Bandundu and Maniema provinces. Baseline prevalence and intensity of infection for SCH and STH were determined to establish the appropriate treatment plan using Praziquantel (PZQ) and Albendazole (ALB)...
November 22, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27884213/regional-variation-in-ascaris-lumbricoides-and-trichuris-trichiura-infections-by-age-cohort-and-sex-effects-of-market-integration-among-the-indigenous-shuar-of-amazonian-ecuador
#6
Theresa E Gildner, Tara J Cepon-Robins, Melissa A Liebert, Samuel S Urlacher, Felicia C Madimenos, J Josh Snodgrass, Lawrence S Sugiyama
BACKGROUND: Soil-transmitted helminth (STH) infection peaks during childhood and varies by sex. The impact of market integration (MI) (increasing production for and consumption from a market-based economy) on these infection patterns, however, is unclear. In this study, STH infection is examined by sex and age among indigenous Shuar inhabiting two regions of Amazonian Ecuador: (1) the modestly market-integrated Upano Valley (UV) and (2) the more traditional Cross-Cutucú (CC) region. METHODS: Kato-Katz fecal smears were examined for parasite presence and infection intensity...
November 24, 2016: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/27876961/intestinal-helminth-infections-among-children-of-district-shopian-of-kashmir-valley-india
#7
Showkat Ahmad Wani, Ayshia Amin
Intestinal helminth infections are amongst the most common infections worldwide. Studies in other districts of Kashmir Valley revealed a high prevalence of intestinal helminth infections among the children. The objectives of the current study were to determine the prevalence of intestinal helminth infections among children of Shopian district and to identify associated socio-demographic and environmental actors, behavioral habits and also related complaints. Stool samples were collected from 352 children and a questionnaire was filled for each case...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876944/seasonal-incidence-of-parasitic-diseases-in-bovines-of-south-western-gujarat-junagadh-india
#8
Binod Kumar, B R Maharana, Amit Prasad, Joice P Joseph, Bhavika Patel, J S Patel
The current study was conducted to investigate the incidence of parasitic diseases in bovines which were sick and brought at veterinary hospital for treatment. A total of 366 samples were investigated from cattle (n = 175) and buffaloes (n = 191) presented at Teaching Veterinary Clinical Complex (TVCC), Veterinary College, Junagadh, Gujarat during January to December 2014. Examination of Giemsa-stained peripheral blood smears exhibited that 58.6 % of cattle and 41.2 % of buffaloes were infected with haemoparasites comprising Babesia bigemina, Theileria annulata, and Anaplasma marginale @ of 54...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27872753/multifunctional-thioredoxin-like-protein-from-the-gastrointestinal-parasitic-nematodes-strongyloides-ratti-and-trichuris-suis-affects-mucosal-homeostasis
#9
Dana Ditgen, Emmanuela M Anandarajah, Jan Hansmann, Dominic Winter, Guido Schramm, Klaus D Erttmann, Eva Liebau, Norbert W Brattig
The cellular redox state is important for the regulation of multiple functions and is essential for the maintenance of cellular homeostasis and antioxidant defense. In the excretory/secretory (E/S) products of Strongyloides ratti and Trichuris suis sequences for thioredoxin (Trx) and Trx-like protein (Trx-lp) were identified. To characterize the antioxidant Trx-lp and its interaction with the parasite's mucosal habitat, S. ratti and T. suis Trx-lps were cloned and recombinantly expressed. The primary antioxidative activity was assured by reduction of insulin and IgM...
2016: Journal of Parasitology Research
https://www.readbyqxmd.com/read/27853119/a-first-case-of-human-trichuriasis-from-a-roman-lead-coffin-in-france
#10
Benjamin Dufour, Maxence Segard, Matthieu Le Bailly
A paleoparasitological study was carried out on 2 lead coffins recovered from the Roman site of Jaunay-Clan (near Poitiers, France). For the first time, this particular type of burial gave positive parasitological results, and eggs of the whipworm Trichuris trichiura were identified in 1 individual. In the present case, thanatomorphose associated with funerary practices may explain the scarcity of the recovered eggs. However, human whipworm has now been observed in 9 individuals dated to the Roman period. The very high frequency of Trichuris sp...
October 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27806992/the-whipworm-trichuris-suis-secretes-prostaglandin-e2-to-suppress-proinflammatory-properties-in-human-dendritic-cells
#11
Lisa C Laan, Andrew R Williams, Kathrin Stavenhagen, Martin Giera, Gijs Kooij, Iliyan Vlasakov, Hakan Kalay, Helene Kringel, Peter Nejsum, Stig M Thamsborg, Manfred Wuhrer, Christine D Dijkstra, Richard D Cummings, Irma van Die
Clinical trials have shown that administration of the nematode Trichuris suis can be beneficial in treating various immune disorders. To provide insight in the mechanisms by which this worm suppresses inflammatory responses, an active component was purified from T. suis-soluble products (TsSPs) that suppress---- TNF and IL-12 secretion from LPS-activated human dendritic cells (DCs). Analysis by liquid chromatography tandem mass spectrometry identified this compound as prostaglandin (PG)E2. The purified compound showed similar properties compared with TsSPs and commercial PGE2 in modulating LPS-induced expression of many cytokines and chemokines and in modulating Rab7B and P2RX7 expression in human DCs...
November 2, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/27806464/determination-of-geohelminthiasis-and-its-association-with-allergic-sensitization-among-selected-children-in-batangas-philippines
#12
Carina R Magbojos, Shereen O Chua, Charlene R Alegria, Faustina C Macalalad, Anne Camille R Malayba, Alyssa Andrea D Mandigma, Oliver Shane R Dumaoal
Several studies have explored the cross-reactivity between geohelminthiasis and allergy which share the same immune response in humans by triggering the increase in serum IgE level. Yet, the role of soil-transmitted intestinal parasitism as a protective or contributing factor for allergy remains inconclusive. In this study, the association of geohelminthiasis with allergic sensitization was investigated in a cohort of 50 children aged 5 to 12 years old residing in the areas of Batangas, Philippines where parasitism is prevalent...
June 30, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27806046/migrant-workers-in-malaysia-current-implications-of-sociodemographic-and-environmental-characteristics-in-the-transmission-of-intestinal-parasitic-infections
#13
Norhidayu Sahimin, Yvonne A L Lim, Farnaza Ariffin, Jerzy M Behnke, John W Lewis, Siti Nursheena Mohd Zain
A cross-sectional study of intestinal parasitic infections amongst migrant workers in Malaysia was conducted. A total of 388 workers were recruited from five sectors including manufacturing, construction, plantation, domestic and food services. The majority were recruited from Indonesia (n = 167, 43.3%), followed by Nepal (n = 81, 20.9%), Bangladesh (n = 70, 18%), India (n = 47, 12.1%) and Myanmar (n = 23, 5.9.2%). A total of four nematode species (Ascaris lumbricoides, Trichuris trichiura, Enterobius vermicularis and hookworms), one cestode (Hymenolepis nana) and three protozoan species (Entamoeba histolytica/dispar, Giardia sp...
November 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27793110/effect-of-anthelminthic-treatment-on-helminth-infection-and-related-anaemia-among-school-age-children-in-northwestern-ethiopia
#14
Yonas Yimam, Abraham Degarege, Berhanu Erko
BACKGROUND: Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and intensity of intestinal helminth infection, haemoglobin level and prevalence of anaemia among school-age children. METHODS: A total of 403 children attending Tikur Wuha Elementary School in Jiga, northwestern Ethiopia were enrolled in this study between February and March 2011...
October 28, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27790963/comparison-between-merthiolate-iodine-formalin-and-kato-katz-methods-for-the-diagnosis-of-human-helminth-infections-in-resource-limited-settings
#15
R N Incani, T Homan, E Pinelli, L Mughini-Gras, H Guevara, J Jesus
Diagnosis of intestinal parasites through examination of fresh faecal samples is hampered by its unpleasantness and the urgent need to detect all parasitic forms. In this paper, we compared the standard Kato-Katz (KK) technique with a traditional fixation method, the merthiolate-iodine-formalin (MIF) method. Two hundred and twenty-seven faecal samples from individuals living in a rural setting in Venezuela with high to moderate prevalences of Ascaris lumbricoides (Al), Trichuris trichiura (Tt) and hookworm infections were examined...
October 28, 2016: Journal of Helminthology
https://www.readbyqxmd.com/read/27788020/nematofauna-of-rodents-of-the-families-heteromyidae-and-cricetidae-from-the-mexican-plateau
#16
Josà Carlos Iturbe-Morgado, Jorge Falcà N-Ordaz, Georgina Lira-Guerrero, Jesà S Fernà Ndez, Roxana Acosta
As a part of an ongoing project to inventory the helminth parasites of rodents in Mexico, 85 specimens of 2 families of rodents were collected from the Mexican Plateau: Cricetidae (Neotoma sp., Neotoma leucodon, Onychomys arenicola, Peromyscus sp., Peromyscus eremicus and Reithrodontomys sp.) and Heteromyidae (Chaetodipus sp., Chaetodipus eremicus, Chaetodipus hispidus, Dipodomys merriami, Dipodomys ordii, Dipodomys ornatus, Dipodomys spectabilis, Liomys irroratus, Perognathus sp. and Perognathus flavus). A total of 13 taxa of helminth were found: Heteromyoxyuris longejector, Heteromyoxyuris otomii, Heteromyoxyuris sp...
October 27, 2016: Journal of Parasitology
https://www.readbyqxmd.com/read/27785599/prevalence-and-risk-factors-for-gastrointestinal-parasites-in-small-scale-pig-enterprises-in-central-and-eastern-uganda
#17
Kristina Roesel, Ian Dohoo, Maximilian Baumann, Michel Dione, Delia Grace, Peter-Henning Clausen
In Eastern Africa, small-scale pig keeping has emerged as a popular activity to generate additional household income. Infections of pigs with gastrointestinal helminths can limit production output, increase production costs, and pose zoonotic risks. A cross-sectional, community-based study in three districts in Eastern and Central Uganda examined the prevalence of gastrointestinal helminthes and associated risk factors in 932 randomly sampled pigs. Using the combined sedimentation-flotation method, 61.4 % (58...
October 26, 2016: Parasitology Research
https://www.readbyqxmd.com/read/27771803/efficacy-against-nematode-infections-and-safety-of-afoxolaner-plus-milbemycin-oxime-chewable-tablets-in-domestic-dogs-under-field-conditions-in-europe
#18
Steffen Rehbein, Martin Knaus, Yasmina Mallouk, Tatjana Breiltgens, Emanuele Brianti, Balázs Capári, Filipe Dantas-Torres, Michel Gau, Anja Joachim, Karl-Heinz Kaulfuß, Zvezdelina Kirkova, Joerg Lechner, Andrei D Mihalca, Rosamaria Mirabito, Saulius Petkevičius, Dhimitër Rapti, Enstela Shukullari, Michel Sedeilhan, Doris Dollhofer, Katrin Kley, Wilfried Lebon, Martin Visser, Philippe Jeannin
Afoxolaner (AFX) plus milbemycin oxime (MO) combination chewable tablets (NexGard Spectra®, Merial) were evaluated for safety and efficacy against naturally acquired nematode infections in domestic dogs in a multi-centre, positive control, blinded field study using a randomized block design based on the order of presentation for allocation. In total, 408 dogs confirmed positive for naturally acquired infections of intestinal nematodes by pre-treatment faecal examination were studied in ten countries in Europe (Albania, Austria, Bulgaria, France, Germany, Hungary, Italy, Lithuania, Romania and Slovakia)...
October 22, 2016: Parasitology Research
https://www.readbyqxmd.com/read/27770198/production-and-characterization-of-a-monoclonal-antibody-specific-to-16%C3%A2-kda-antigen-of-paramphistomum-gracile
#19
Panat Anuracpreeda, Amaya Watthanadirek, Runglawan Chawengkirttikul, Prasert Sobhon
A number of monoclonal antibodies (MoAbs) against the 16 kDa antigen of Paramphistomum gracile (16 kDaAgPg) were produced in vitro by hybridoma technique. Reactivity and specificity of these MoAbs were evaluated by ELISA and immunoblotting assays. Seven MoAb clones were selected from the stable hybridoma clones, namely 1D10, 2D7, 3B10, 3D9, 4F1, 4G4, and 5G12. It was found to be IgM and kappa light chain isotypes. By immunoblotting and ELISA, all MoAbs reacted with purified 16 kDaAgPg at molecular weight (MW) of 16 kDa and with the native 16 kDa antigen at MW of 16 kDa in the whole body (WB) and excretory-secretory (ES) fractions, but not with tegumental antigens (TA) of adult fluke...
October 22, 2016: Parasitology Research
https://www.readbyqxmd.com/read/27761403/rangelia-vitalii-in-a-free-ranging-maned-wolf-chrysocyon-brachyurus-and-co-infections
#20
Julia Angélica Gonçalves Silveira, Mirella Lauria D'Elia, Isabela de Oliveira Avelar, Lara Ribeiro de Almeida, Hudson Andrade Dos Santos, Danielle Ferreira de Magalhães Soares, Múcio Flávio Barbosa Ribeiro, Walter Dos Santos Lima, Roselene Ecco
An adult free-ranged female maned wolf was rescued from a periurban area subject to anthropogenic disturbances in the Minas Gerais, Brazil. The animal presented poor body condition and anemia. The clinical condition rapidly deteriorated culminating in dead and a necropsy was performed. The main gross lesions were marked anemia and blood content in the intestines accompanied by many types of parasites. The protozoa Rangelia vitalii was identified by histopathological analysis predominantly within the cytoplasm of endothelial cells of capillaries of the small intestine...
December 2016: International Journal for Parasitology. Parasites and Wildlife
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