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https://www.readbyqxmd.com/read/28319798/cold-plasma-activated-hydrogen-peroxide-aerosol-inactivates-escherichia-coli-o157-h7-salmonella-typhimurium-and-listeria-innocua-and-maintains-quality-of-grape-tomato-spinach-and-cantaloupe
#1
Yunbin Jiang, Kimberly Sokorai, Georgios Pyrgiotakis, Philip Demokritou, Xihong Li, Sudarsan Mukhopadhyay, Tony Jin, Xuetong Fan
The purpose of this study was to investigate the efficacy of aerosolized hydrogen peroxide in inactivating bacteria and maintaining quality of grape tomatoes, baby spinach leaves and cantaloupes. Stem scars and smooth surfaces of tomatoes, spinach leaves, and cantaloupe rinds, inoculated with Escherichia coli O157:H7, Salmonella Typhimurium and Listeria innocua, were treated for 45s followed by additional 30min dwell time with hydrogen peroxide (7.8%) aerosols activated by atmospheric cold plasma. Non-inoculated samples were used to study the effects on quality and native microflora populations...
March 10, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28319643/grooved-glaucoma-drainage-devices-that-continuously-deliver-cyclosporine-a-decrease-postsurgical-scar-formation-in-rabbit-eyes
#2
Zhaoxing Dai, Xiaobo Yu, Jianguo Sun, Xinghuai Sun
Purpose: To study the functional outcomes of filtration surgery by implanting improved glaucoma drainage devices (GDDs) comprising surface grooves and a composite coating of cyclosporine A (CsA) and PLGA in experimental rabbit eyes. Methods: Improved GDDs were designed and prepared by modifying normal GDD with surface grooves and a CsA-PLGA composite coating. Normal GDDs, grooved GDDs (G-GDDs), and G-GDDs with a CsA-PLGA composite coating (CsA@G-GDD) were implanted into 18 rabbit eyes (six eyes per group)...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28319528/postburn-microstomia-prevention-using-an-appliance-providing-simultaneous-horizontal-and-vertical-adjustable-forces
#3
Gregory S Antonarakis, Sandra Fastlicht, Taras Masnyi, Bryan Tompson
Microstomia, an abnormally small oral orifice, is a complication of perioral facial burns. In this case, contraction of the circumoral tissues and hypotonia of the musculature is responsible for this microstomia, which can produce aesthetic and functional impairment with eating, swallowing, communication (speech and facial expressions), compromised dental care and maintenance due to limited oral access, social interactions, and psychological well-being. Conservative management involves providing physical resistance to scar contracture, with opposing horizontal and vertical circumoral forces by means of appliances that aim to stretch the commissures and fibrotic muscles...
March 13, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28319503/myocardial-infarction-in-a-patient-with-hypertrophic-cardiomyopathy-but-normal-coronary-arteries
#4
Shuheng Li, Xiaoxin Sun, Zongyao Zhang, Zuo-Xiang He
A 57-year-old man with a history of hypertrophic cardiomyopathy diagnosed by echocardiography experienced atypical chest pain and dyspnea for 6 months. A rest Tc-MIBI myocardial SPECT imaging and a F-FDG myocardial PET/CT imaging were performed, which showed multiple matched myocardial perfusion/metabolism defects in the left ventricle, indicating scar tissue. Surprisingly, subsequent contrast coronary angiography revealed no significant coronary artery stenosis.
March 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28319267/risk-factors-associated-with-failure-of-treatment-for-cesarean-scar-pregnancy
#5
Ying-Cheng Chiang, Yi-An Tu, Jehn-Hsiahn Yang, Shin-Yu Lin, Chien-Nan Lee, Jin-Chung Shih
OBJECTIVE: To identify risk factors associated with treatment failure among women with cesarean scar pregnancy (CSP). METHODS: In a retrospective study, the medical records of patients with CSP treated at National Taiwan University Hospital, Taipei, Taiwan, from 1994 to 2015 were reviewed. The women were managed primarily with hysterotomy, evacuation, or methotrexate. Receiver operating characteristic (ROC) curve analysis and logistic regression analysis were used to evaluate the factors associated with treatment failure...
March 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28318785/biodegradation-of-polyester-polyurethane-by-aspergillus-tubingensis
#6
Sehroon Khan, Sadia Nadir, Zia Ullah Shah, Aamer Ali Shah, Samantha C Karunarathna, Jianchu Xu, Afsar Khan, Shahzad Munir, Fariha Hasan
The xenobiotic nature and lack of degradability of polymeric materials has resulted in vast levels of environmental pollution and numerous health hazards. Different strategies have been developed and still more research is being in progress to reduce the impact of these polymeric materials. This work aimed to isolate and characterize polyester polyurethane (PU) degrading fungi from the soil of a general city waste disposal site in Islamabad, Pakistan. A novel PU degrading fungus was isolated from soil and identified as Aspergillus tubingensis on the basis of colony morphology, macro- and micro-morphology, molecular and phylogenetic analyses...
March 15, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28318638/optical-coherence-tomography-guided-decisions-in-retinoblastoma-management
#7
Sameh E Soliman, Cynthia VandenHoven, Leslie D MacKeen, Elise Héon, Brenda L Gallie
PURPOSE: Assess the role of handheld optical coherence tomography (OCT) in guiding management decisions during diagnosis, treatment, and follow-up of eyes affected by retinoblastoma. DESIGN: Retrospective, noncomparative, single-institution case series. PARTICIPANTS: All children newly diagnosed with retinoblastoma from January 2011 to December 2015 who had an OCT session during their active treatment at The Hospital for Sick Children (SickKids) in Toronto, Canada...
March 15, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28318040/clinical-and-laboratory-characteristics-of-a-tinea-capitis-outbreak-among-novice-buddhist-monks
#8
Sumanas Bunyaratavej, Charussri Leeyaphan, Chuda Rujitharanawong, Chanai Muanprasat, Lalita Matthapan
Sixty novice Buddhist monks with tinea capitis confirmed according to clinical presentation and mycological laboratory finding were included in this study. Mixed-type clinical presentation was observed in approximately half of all cases, together with scarring alopecia (95%) and superficial fungal skin infection at locations other than the scalp (43.3%). The major isolated organism was Trichophyton violaceum, and mixed-organism infection was found in 27 cases (45%). Slow-onset presentation and an extensive area of infection were significantly associated with mixed-type clinical presentation...
March 20, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28317912/the-soft-mechanical-signature-of-glial-scars-in-the-central-nervous-system
#9
Emad Moeendarbary, Isabell P Weber, Graham K Sheridan, David E Koser, Sara Soleman, Barbara Haenzi, Elizabeth J Bradbury, James Fawcett, Kristian Franze
Injury to the central nervous system (CNS) alters the molecular and cellular composition of neural tissue and leads to glial scarring, which inhibits the regrowth of damaged axons. Mammalian glial scars supposedly form a chemical and mechanical barrier to neuronal regeneration. While tremendous effort has been devoted to identifying molecular characteristics of the scar, very little is known about its mechanical properties. Here we characterize spatiotemporal changes of the elastic stiffness of the injured rat neocortex and spinal cord at 1...
March 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28317000/surgical-treatment-algorithms-for-post-burn-contractures
#10
REVIEW
Kenji Hayashida, Sadanori Akita
Burn contractures produce restrictions in motion and unacceptable aesthetic results, frequently with persistent wounds. Proper planning and tissue selection are essential to minimize donor site morbidity optimizing outcomes. The principle of burn reconstructive surgery requires that the defects after release should be replaced with donor tissues which have matching texture and color as well as enough pliability. Autologous skin grafting or flap surgeries meet these criteria to replace scar tissues and resurface the subsequent to post-released scar defects...
2017: Burns and trauma
https://www.readbyqxmd.com/read/28316188/-concerns-on-the-diagnosis-and-treatment-of-corneal-epitheliopathy
#11
W Y Shi
Corneal epitheliopathy is a commonly seen disease in the clinical work. However, due to its complicated causes, there remain misdiagnosis and mistreatment, which would aggravate epithelial keratopathy and induce corneal scars, eventually leading to irreversible visual impairment. In this article, the primary and secondary causes of corneal epithelial lesions are described in detail. The classification, diagnosis and treatment principles of the disease are also presented to arouse more concern about corneal epitheliopathy...
March 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28316164/-advances-in-the-research-of-signaling-pathway-in-pathologic-scar-formation
#12
J Jin, B Ma, Z F Xia
Scar is the natural end of wound healing, but pathologic scar will form with the excessive hyperplasia. The problems which thus come not only include the physiological and psychological disorders caused by the change of appearance or dysfunction, but also include the economic burden for both families of the patients and society induced by the requirement of plastic or functional reconstruction. The formation of pathologic scars is affected by many factors involved in the process of wound healing, such as excessive inflammation, abnormal tissue repair, and lingering repair termination, which involve a lot of signaling pathways...
March 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28316163/-effects-of-silencing-smad-ubiquitination-regulatory-factor-2-on-the-function-of-human-hypertrophic-scar-derived-fibroblasts
#13
Z Zhang, F Kuang, C L Liu, B Chen, W B Tang, X J Li
Objective: To explore the effects of silencing Smad ubiquitination regulatory factor 2 (Smurf2) on the secretion of transforming growth factor beta 1 (TGF-β(1)), alpha-smooth muscle actin (α-SMA), and collagen type Ⅰ by human hypertrophic scar-derived fibroblasts. Methods: The human normal skin-derived fibroblasts and hypertrophic scar-derived fibroblasts were cultured with explant culture technique from the normal skin and hypertrophic scar tissue, which was obtained from 9 patients with hypertrophic scars after burn...
March 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28316162/-observation-on-the-clinical-application-effects-of-skin-distractor-on-the-treatment-of-scars
#14
W L Gui, E Yang, H S Zhang
Objective: To explore clinical application effects of skin distractor on the treatment of scars and to observe effects of skin distractor with different pull speeds on different parts scars of human body. Methods: One hundred and four patients with scars, conforming to the study criteria, were hospitalized in our unit from January 2014 to June 2015. Patients were divided into 2 mm/d group and 4 mm/d group according to the random number table, with 52 patients in each group. After admission, skin distractors were pasted on scars in face and neck, trunk, and extremities of patients in 2 groups, with inner edges of pasteboards close to outside edges of longer sides of scars...
March 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28316023/transconjunctival-versus-subciliary-approach-to-the-infraorbital-margin-for-open-reduction-of-zygomaticomaxillary-complex-fractures-a-randomized-feasibility-study
#15
Mohammad Waheed El-Anwar, Ezzeddin Elsheikh, Atef M Hussein, Adly A Tantawy, Youssef Mansour Abdelbaki
INTRODUCTION: Although some studies addressed the differences between subciliary and transconjunctival approaches, no previous prospective comparative study on displaced zygomaticomaxillary complex (ZMC) fracture that repaired by three-point internal fixation using also upper gingivolabial incision and upper eye lid incision. So, the effect of these incisions on the comparison was not investigated. PURPOSE: The purpose of this study was to compare transconjunctival and subciliary approaches for open reduction and internal rigid fixation (OR/IF) of ZMC fractures...
March 18, 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28315515/tailored-corneo-conjunctival-autografting-in-primary-and-secondary-pterygium-surgery
#16
Mahmoud M Genidy, Ahmed A Abdelghany, Jorge L Alio
PURPOSE: To describe the outcomes of a novel technique for pterygium removal: tailored corneo-conjunctival autograft, which offers the advantages of better postoperative cosmetic outcomes and recurrence prevention. METHODS: This retrospective interventional noncomparative study included 420 eyes in 370 patients (ages 25-60 years) (127 women, 243 men). We divided the patients into 2 groups. The first group included 348 primary pterygium; the second group included 72 recurrent pterygium...
February 28, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28314802/an-ex-vivo-model-to-induce-early-fibrosis-like-changes-in-human-precision-cut-lung-slices
#17
Hani N Alsafadi, Claudia A Staab-Weijnitz, Mareike Lehmann, Michael Lindner, Britta Peschel, Melanie Königshoff, Darcy Elizabeth Wagner
IPF is a devastating chronic interstitial lung disease (ILD) characterized by lung tissue scarring and high morbidity. Lung epithelial injury, myofibroblast activation, and deranged repair are believed to be key processes involved in disease onset and progression but the exact molecular mechanisms behind IPF remain unclear. Several drugs have been shown to slow disease progression, but treatments which halt or reverse IPF progression have not been identified. Ex vivo models of human lung have been proposed for drug discovery, one of which is precision-cut lung slices (PCLS)...
March 17, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28314473/complex-regional-pain-syndrome-in-burn-pathological-scarring-a-case-report-and-review-of-the-literature
#18
Suman Mewa Kinoo, Bhugwan Singh
Chronic pain in burn pathological scarring is not an uncommon occurrence. The mechanisms of pain are not clearly understood and hence the management approach is often a daunting task. However, meticulous physical examination of these patients may classify them as complex regional pain syndrome, type I. We present a patient with classic signs and symptoms of complex regional pain syndrome associated with burn pathological scarring of her left forearm that had a favourable response to a thoracoscopic sympathectomy...
March 14, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28314226/long-term-follow-up-of-mucous-membrane-grafting-for-cicatricial-ectropion-in-ichthyosis-a-case-report
#19
Hind Manaa Alkatan, Manar A Aljebreen, Adel H Alsuhaibani
INTRODUCTION: Ichthyosis is a group of keratinizing diseases characterized by scaly and dry skin. One of the ocular complications associated with ichthyosis is cicatricial ectropion which often results in exposure keratopathy and eventually corneal scarring. PRESENTATION OF CASE: In this report we are presenting a 21-year-old female who is known to have ichthyosis-related bilateral lower lid cicatricial ectropion, which was managed with Mucous Membrane Grafting (MMG) six years ago...
February 16, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28304218/comparative-effectiveness-of-flexible-versus-rigid-neuroendoscopy-for-endoscopic-third-ventriculostomy-and-choroid-plexus-cauterization-a-propensity-score-matched-cohort-and-survival-analysis
#20
Shelly Wang, Scellig Stone, Alexander G Weil, Aria Fallah, Benjamin C Warf, John Ragheb, Sanjiv Bhatia, Abhaya V Kulkarni
OBJECTIVE Endoscopic third ventriculostomy (ETV)/choroid plexus cauterization (CPC) has become an increasingly common technique for the treatment of infant hydrocephalus. Both flexible and rigid neuroendoscopy can be used, with little empirical evidence directly comparing the two. Therefore, the authors used a propensity score-matched cohort and survival analysis to assess the comparative efficacy of flexible and rigid neuroendoscopy. METHODS Individual data were collected through retrospective review of infants younger than 2 years of age, treated at 1 of 2 hospitals: 1) Boston Children's Hospital, exclusively utilizing flexible neuroendoscopy, and 2) Nicklaus Children's Hospital-Jackson Memorial Hospital, exclusively utilizing rigid neuroendoscopy...
March 17, 2017: Journal of Neurosurgery. Pediatrics
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