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https://www.readbyqxmd.com/read/29274214/helminth-infections-in-faecal-samples-of-apennine-wolf-canis-lupus-italicus-and-marsican-brown-bear-ursus-arctos-marsicanus-in-two-protected-national-parks-of-central-italy
#1
Barbara Paoletti, Raffaella Iorio, Donato Traversa, Cristina E Di Francesco, Leonardo Gentile, Simone Angelucci, Cristina Amicucci, Roberto Bartolini, Marianna Marangi, Angela Di Cesare
This article reports the results of a copromicroscopic and molecular investigation carried out on faecal samples of wolves (n=37) and brown bears (n=80) collected in two protected national parks of central Italy (Abruzzo Region). Twenty-three (62.2%) samples from wolves were positive for parasite eggs. Eight (34.78%) samples scored positive for single infections, i.e. E. aerophilus (21.74%), Ancylostoma/Uncinaria (4.34%), Trichuris vulpis (4.34%), T. canis (4.34%). Polyspecific infections were found in 15 samples (65...
2017: Annals of Parasitology
https://www.readbyqxmd.com/read/29261231/the-study-of-host-immune-responses-elicited-by-the-model-murine-hookworms-nippostrongylus-brasiliensis-and-heligmosomoides-polygyrus
#2
T Bouchery, B Volpe, K Shah, L Lebon, K Filbey, G LeGros, N Harris
Hookworm infections (Necator americanus or Ancylostoma duodenale) represent a major neglected tropical disease, affecting approximately 700 million people worldwide, and can cause severe morbidity due to the need for these worms to feed on host blood. N. brasiliensis and H. polygrus, both rodent parasites, are the two most commonly employed laboratory models of experimental hookworm infection. Both parasites evoke type 2 immune responses, and their use has been instrumental in generating fundamental insight into the molecular mechanisms of type-2 immunity and for understanding how the immune response can control parasite numbers...
December 20, 2017: Current Protocols in Mouse Biology
https://www.readbyqxmd.com/read/29246169/ancylostoma-ceylanicum-infective-third-stage-larvae-are-activated-by-co-culture-with-ht-29-mtx-intestinal-epithelial-cells
#3
Caitlin M Feather, John M Hawdon, John C March
BACKGROUND: Human hookworm larvae arrest development until they enter an appropriate host. This makes it difficult to access the larvae for studying larval development or host-parasite interactions. While there are in vivo and in vitro animal models of human hookworm infection, there is currently no human, in vitro model. While animal models have provided much insight into hookworm biology, there are limitations to how closely this can replicate human infection. Therefore, we have developed a human, in vitro model of the initial phase of hookworm infection using intestinal epithelial cell culture...
December 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29173542/regression-models-to-assess-the-risk-factors-of-canine-gastrointestinal-parasitism
#4
I Symeonidou, A Ι Gelasakis, K V Arsenopoulos, R Schaper, E Papadopoulos
Gastrointestinal parasites, protozoa and helminths, remain a common important finding in dogs presented to veterinary medical practices. Moreover, dogs may play an active role in the transmission of enteric parasites to humans, given their cohabitation, making canine gastrointestinal parasitism an issue of major concern for public health. To get an overview of the current state of canine gastrointestinal parasites' prevalence in Greece, a total of 1036 faecal samples were collected from dogs either presented in veterinary clinics or in animal shelters...
December 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29160359/gastrointestinal-parasites-in-feral-cats-and-rodents-from-the-fernando-de-noronha-archipelago-brazil
#5
Victor Fernando Santana Lima, Rafael Antonio Nascimento Ramos, Raphael Lepold, João Carlos Gomes Borges, Carlos Diógenes Ferreira, Laura Rinaldi, Giuseppe Cringoli, Leucio Câmara Alves
Gastrointestinal parasites are important pathogens affecting animals, some of them are of medical and veterinary concern. Although the dynamic of parasitic infections is a complex phenomenon that has been studied under experimental conditions, it shows several gaps in knowledge, especially in insular regions where a confined population of animals and parasites co-exists. In this study was assessed the parasitism by endoparasite gastrointestinal in feral cats (n = 37) and rodents (n = 30) from the Fernando de Noronha Archipelago; in addition, the risk of human infection and ecological implications of these findings were discussed...
November 9, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/29157661/analysis-of-codon-usage-pattern-of-mitochondrial-protein-coding-genes-in-different-hookworms
#6
Bornali Deb, Arif Uddin, Gulshana Akthar Mazumder, Supriyo Chakraborty
The phenomenon of unequal usage of synonymous codons encoding an amino acid in which some codons are more preferred to others is the codon usage bias (CUB) and it is species specific. Analysis of CUB helps in understanding evolution at molecular level and acquires significance in mRNA translation, design of transgenes and new gene discovery. In our current study, we analyzed synonymous codon usage pattern and the factors influencing it on mitochondrial protein coding genes of 6 different hookworms i.e. Ancylostoma ceylanicum, Ancylostoma duodenale, Necator americanus, Ancylostoma tubaeforme, Ancylostoma caninum and Uncinaria sanguinis as no work was reported yet...
November 17, 2017: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/29138640/prevalence-of-soil-transmitted-helminthiases-and-schistosomiasis-in-preschool-age-children-in-mwea-division-kirinyaga-south-district-kirinyaga-county-and-their-potential-effect-on-physical-growth
#7
Stephen Sifuna Wefwafwa Sakari, Amos K Mbugua, Gerald M Mkoji
Intestinal parasitic infections can significantly contribute to the burden of disease, may cause nutritional and energetic stress, and negatively impact the quality of life in low income countries of the world. This cross-sectional study done in Mwea irrigation scheme, in Kirinyaga, central Kenya, assessed the public health significance of soil-transmitted helminthiases (STH), schistosomiasis, and other intestinal parasitic infections, among 361 preschool age children (PSAC) through fecal examination, by measuring anthropometric indices, and through their parents/guardians, by obtaining sociodemographic information...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29114490/evaluation-of-the-utility-of-conventional-polymerase-chain-reaction-for-detection-and-species-differentiation-in-human-hookworm-infections
#8
Meenachi Chidambaram, Subhash Chandra Parija, Pampa Ch Toi, Jharna Mandal, Dhanalakshmi Sankaramoorthy, Santosh George, Mailan Natarajan, Shashiraja Padukone
Background: Human hookworm infection is caused mainly by Necator americanus and Ancylostoma duodenale. Among the zoonotic hookworm species, only Ancylostoma ceylanicum causes potent human infections where dogs and cats act as reservoir of infection. Hence, species differentiation is imperative because the eradication of both anthroponotic and zoonotic hookworm depends on the concurrent human and animal health programs, hygienic practices, and mass drug administration for humans and dogs...
July 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/29114485/laboratory-diagnosis-of-soil-transmitted-helminthiasis
#9
Sumeeta Khurana, Shveta Sethi
Soil-transmitted helminths (STHs) include, i.e., hookworms (Ancylostoma duodenale, Necator americanus), roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura) and Strongyloides stercoralis. Globally, around 1.5 billion people are infected with STHs. STHs contribute to significant impairment of mental and physical growth, especially in developing countries. Unfortunately, these infections mostly remain undiagnosed due to lack of trained personnel and appropriate technologies. Intermittent shedding of eggs or larvae further makes the diagnosis difficult...
July 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/29114484/epidemiology-and-clinical-features-of-soil-transmitted-helminths
#10
Subhash Chandra Parija, Meenachi Chidambaram, Jharna Mandal
Soil-transmitted helminths (STH) consist of Ascaris lumbricoides, Trichuris trichiura, and hookworm (Necator americanus and Ancylostoma duodenale). It affects nearly 1.7 billion people globally in which Ascaris contributes nearly 1.2 billion cases. The main mode for transmission of Ascaris and Trichuris is through contaminated food and water, whereas hookworm transmitted by skin penetration. STH were mainly seen in areas with poverty, overcrowding, and poor sanitation. The prevalence is more in rural areas compared to urban areas...
July 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/29114134/epidemiological-investigation-of-gastrointestinal-parasites-in-dog-populations-in-basra-province-southern-iraq
#11
Khawla B N Al-Jassim, Yasser S Mahmmod, Zainab M Salem, Azmi Al-Jubury
The understanding of the epidemiology of canine parasitic infections is necessary for an efficient control program to minimize the risk of zoonotic transmission. The objectives of this study were (1) to determine the prevalence of canine gastrointestinal helminths and protozoa in Basra province, Southern Iraq, and (2) to identify the association of epidemiological characteristics (age, breed, gender, and feed type) of dogs with the parasitic infections. A total of 93 fecal samples, collected in the period from December 2014 to June 2015, were examined macroscopically and microscopically for the presence of worm eggs and protozoal oocysts, using centrifugal flotation method...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29108026/status-of-soil-transmitted-helminth-infections-in-schoolchildren-in-laguna-province-the-philippines-determined-by-parasitological-and-molecular-diagnostic-techniques
#12
Mary Lorraine S Mationg, Catherine A Gordon, Veronica L Tallo, Remigio M Olveda, Portia P Alday, Mark Donald C Reñosa, Franziska A Bieri, Gail M Williams, Archie C A Clements, Peter Steinmann, Kate Halton, Yuesheng Li, Donald P McManus, Darren J Gray
BACKGROUND: Soil-transmitted helminths (STH) are the most common parasitic infections in impoverished communities, particularly among children. Current STH control is through school-based mass drug administration (MDA), which in the Philippines is done twice annually. As expected, MDA has decreased the intensity and prevalence of STH over time. As a result, the common Kato Katz (KK) thick smear method of detecting STH is less effective because it lacks sensitivity in low intensity infections, making it difficult to measure the impact of deworming programs...
November 6, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29080756/diagnostic-strategies-to-reveal-covert-infections-with-intestinal-helminths-in-dogs
#13
Chris Adolph, Sharon Barnett, Melissa Beall, Jason Drake, David Elsemore, Jennifer Thomas, Susan Little
Intestinal helminths are common in dogs in the United States, particularly non-treated dogs in animal shelters, but surveys by fecal flotation may underestimate their prevalence. To determine the prevalence of intestinal helminths and evaluate the ability of fecal flotation and detection of nematode antigen to identify those infections, contents of the entire gastrointestinal tract of 97 adult (>1year) dogs previously identified for humane euthanasia at two animal control shelters in northeastern Oklahoma, USA, were screened...
November 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29052354/revisiting-the-ancylostoma-caninum-secretome-provides-new-information-on-hookworm-host-interactions
#14
Taylor Morante, Catherine Shepherd, Constantin Constantinoiu, Alex Loukas, Javier Sotillo
Hookworm infection is a major tropical parasitic disease affecting almost 500 million people worldwide. These soil-transmitted helminths can survive for many years in the intestine of the host, where they feed on blood, causing iron deficiency anaemia and other complications. These parasites release a variety of molecules known as excretory/secretory products (ESPs) that are involved in many different biological processes that govern parasite survival. Using a combination of separation techniques such as SDS-PAGE and OFFGEL electrophoresis, in combination with state-of-the-art mass spectrometry we have reanalysed the dog hookworm, Ancylostoma caninum, ESPs (AcES)...
October 20, 2017: Proteomics
https://www.readbyqxmd.com/read/29039336/soil-transmitted-helminthiasis-in-different-occupational-groups-in-swat-khyber-pakhtunkhwa-pakistan
#15
Wali Khan, Noorun Nisa, Aly Khan
We investigated the prevalence of geohelminth parasites in farmers, education concerned and shepherd of Swat, Khyber Pakhtunkhwa, Pakistan. A total of 1041 stool samples were examined from January 2006 to December 2008 using direct smear (Normal saline and Lugol's Iodine solution) the concentration methods and procedures. Seven hundred and sixty three (73.2%) individuals were found infected with one or more than one geohelminth parasites. Four hundred and eighteen (54.7%) were infected with single parasite and three hundred forty five (45...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29034951/a-nanocrystal-based-formulation-improves-the-pharmacokinetic-performance-and-therapeutic-response-of-albendazole-in-dogs
#16
Alejandro Javier Paredes, Nicolás Litterio, Alicia Dib, Daniel Alberto Allemandi, Carlos Lanusse, Sergio Sánchez Bruni, Santiago Daniel Palma
OBJECTIVES: Here, we aimed to assess the pharmacokinetic performance and therapeutic response (anthelmintic efficacy) of an albendazole (ABZ) nano-sized formulation in dogs. METHODS: In the pharmacokinetic study, ABZ self-dispersible nanocrystals (SDNCS) and a control formulation were administered orally to healthy dogs (n = 6). The concentrations of the sulphoxide metabolite in plasma were determined by high-performance liquid chromatography. For the anthelmintic efficacy trial, SDNCS and a commercially available formulation of ABZ were given to naturally parasitised dogs...
October 16, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28984036/a-cross-sectional-study-of-intestinal-parasitoses-in-dogs-and-children-of-the-periurban-area-of-la-plata-buenos-aires-argentina-zoonotic-importance-and-implications-in-public-health
#17
P Cociancic, M L Zonta, G T Navone
A cross-sectional study was performed between school term dates 2014 and 2015 to diagnose intestinal parasites in dogs and children living with them. The socio-environmental characteristics and hygiene practices of the children were also evaluated in terms of risk factors for parasitic infection of periurban neighbourhoods of La Plata (Buenos Aires, Argentina). Serial coproparasitological samples of 78 dogs and 211 children were analysed by means of concentration and flotation techniques. Socio-environmental variables and hygiene practices of children were evaluated through semi-structured questionnaires which were answered by every family...
October 5, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28968014/-profiles-of-intestinal-polyparasitism-in-a-community-of-the-colombian-amazon-region
#18
Julián A Fernández-Niño, Claudia I Astudillo-García, Laura María Segura, Natalia Gómez, Ángela Skantria Salazar, Juan Hember Tabares, Cristian Andrés Restrepo, Miguel Ángel Ruiz, Myriam Consuelo López, Patricia Reyes
INTRODUCTION: Intestinal parasite infections and polyparasitism are highly prevalent in the most vulnerable populations of developing countries due to environmental, biological and social determinants common in the transmission of parasites. Children between 1 and 15 years of age are the most affected population. OBJECTIVE: To describe the prevalence and profiles of intestinal polyparasitism in 1 to 15 year-old children from native communities in the Colombian Amazon region...
September 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28947636/efficacy-of-recommended-drugs-against-soil-transmitted-helminths-systematic-review-and-network-meta-analysis
#19
REVIEW
Wendelin Moser, Christian Schindler, Jennifer Keiser
Objective To evaluate efficacies of anthelmintic drugs against soil transmitted helminths in terms of cure rates and egg reduction rates.Design Systematic review and network meta-analysis.Data Sources PubMed, ISI Web of Science, Embase, ScienceDirect, the Cochrane Central Register of Clinical Trials, and the World Health Organization library database from 1960 until 31 December 2016.Study selection Randomised controlled trials evaluating the efficacy of a single dose regimen of albendazole, mebendazole, levamisole, and pyrantel pamoate against Ascaris lumbricoides, hookworm (Necator americanus and Ancylostoma duodenale) and Trichuris trichiura...
September 25, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28906088/bullous-cutaneous-larva-migrans-case-series-and-review-of-atypical-clinical-presentations
#20
Stefano Veraldi, Ermira Çuka, Paolo Pontini, Fabrizio Vaira
Hookworm-related cutaneous larva migrans (HRCLM) is caused by the penetration and migration in the epidermis of larvae of Ancylostoma braziliense and Ancylostoma caninum. It is characterized by slightly raised and erythematous tracks, located especially on the feet. These tracks may be single or multiple, serpiginous or linear, ramified and intertwined, accompanied by pruritus. Atypical clinical presentations of HRCLM are currently more frequent than in the past. We present six patients with bullous HRCLM and discuss the possible pathogenetic factors...
October 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
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