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https://www.readbyqxmd.com/read/29909430/an-intra-oral-approach-to-facial-skin-lumps-a-move-towards-scarless-surgery
#1
Arpan Tahim, Sarah Ali, Leo Cheng
INTRODUCTION: The aim of surgical management of benign facial skin lumps is to remove the lesion in its entirety, with minimal damage to adjacent tissue structures, while maintaining facial aesthetics. A method to achieve these goals is to remove peri-oral lesions in the labial and buccal zones via an intra-oral approach. We report an extended cases series of facial skin lumps that were excised using an intra-oral approach. METHODS: A retrospective analysis was performed on all patients who underwent excisions of benign cutaneous lesions on the face via an intra-oral approach...
June 16, 2018: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29909192/prepuce-sparing-use-of-z-plasty-for-treatment-of-phimosis-and-scarred-foreskin
#2
Michael Benson, Moneer K Hanna
INTRODUCTION AND OBJECTIVES: The desire to preserve the prepuce is often based on cultural norms. Recently, the concept of "genital autonomy" has been invoked to delay circumcision (or any genital altering procedure) until the individual reaches maturity and can make his or her own decision. However, some uncircumcised boys develop one or more episodes of balanitis resulting in scarring of the prepuce and pathologic phimosis which is difficult to treat. Herein we report on the management of severe phimosis and preputial scarring using preputial Z-plasties...
June 8, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29908832/cardiac-resynchronization-therapy-guided-by-cardiac-magnetic-resonance-imaging-a-prospective-single-centre-randomized-study-cmr-crt
#3
Radka Kočková, Kamil Sedláček, Dan Wichterle, Viktor Šikula, Jaroslav Tintěra, Helena Jansová, Alena Pravečková, Renata Langová, Lukáš Krýže, Wael El-Husseini, Markéta Segeťová, Josef Kautzner
BACKGROUND: Cardiac resynchronization therapy (CRT) improves symptoms of heart failure (HF), morbidity and mortality in selected population. The aim of the study was to investigate the impact of cardiac magnetic resonance (CMR)-guided left ventricular (LV) lead placement on clinical outcomes and LV reverse remodelling in CRT recipients. METHODS: Patients with CRT indication were randomized for CMR-guided (CMR group) or electrophysiologically guided (EP group) LV lead placement between 2011 and 2014...
June 6, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29907446/salvaging-the-dehisced-glans-penis
#4
C M White, M K Hanna
OBJECTIVE: The glans penis may show a deep groove (surgically favorable), or may appear flat with an absent sulcus (unfavorable). Glans dehiscence following hypospadias repair, especially after multiple surgeries, frequently results in a scarred, obliterated, or absent urethral plate. The glans penis appears to be flat and grooveless. This study reported on the outcome of a two-stage salvage repair for glans dehiscence in 49 consecutive patients. MATERIALS AND METHODS: Retrospective chart review was performed for all patients who underwent repair for glans dehiscence following hypospadias repair...
May 30, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29907433/laterocaudal-approach-to-the-inferior-rim-of-the-orbit
#5
Andrea Grandoch, Matthias Kreppel, Ali-Farid Safi, Matthias Zirk, Joachim E Zöller
PURPOSE: Fractures of the orbital floor and orbital rim are frequently treated in maxillofacial departments. Various approaches to the orbital floor are described in the literature. We present an investigation of a modified subciliary approach (laterocaudal approach) with respect to its feasibility and clinical outcome. MATERIALS AND METHODS: Our retrospective study investigated 130 well-documented cases of patients with orbital floor fractures who received surgical reconstruction using a laterocaudal approach, and compared the results with the current literature, with a focus on subciliary and transconjunctival approaches...
April 18, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29906228/changes-in-cardiac-resident-fibroblast-physiology-and-phenotype-in-aging
#6
JoAnn Trial, Katarzyna A Cieslik
The cardiac fibroblast plays a central role in tissue homeostasis and in repair after injury. With aging, dysregulated cardiac fibroblasts have a reduced capacity to respond to transforming growth factor-β (TGF-β) and poorly differentiate into contractile myofibroblasts. That results in the formation of an insufficient scar after myocardial infarction (MI). By contrast, in the uninjured aged heart fibroblasts are activated and acquire a pro-fibrotic phenotype that leads to interstitial fibrosis, ventricular stiffness, and diastolic dysfunction, all conditions that may lead to heart failure...
June 15, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29905922/health-and-ecological-aspects-of-stray-cats-in-old-san-juan-puerto-rico-baseline-information-to-develop-an-effective-control-program
#7
Jessica Castro-Prieto, Maria José Andrade-Núñez
The overpopulation of stray cats in urban areas represents a potential risk for humans, as stray cats may carry diseases, such as toxoplasmosis, and virus such as rabies, the feline immunodeficiency, and the feline leukemia. In Old San Juan, a historic neighborhood and one of the most touristic places in Puerto Rico, there is an overpopulation of stray cats. In this study, we generated baseline information fundamental to developing a successful control program by estimating the stray cat population size, density, and spatial distribution...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29905641/surgical-treatment-of-diplopia-in-graves-orbitopathy-patients
#8
Anja Eckstein, Joachim Esser, Michael Oeverhaus, Peerooz Saeed, Hinke Marijke Jellema
PURPOSE: To review the authors' current understanding of motility dysfunction in patients with thyroid eye disease and to summarize appropriate evaluation and available management options. METHODS: Data were retrieved from a systematic search of the literature. RESULTS: Diplopia is one of the most disabling symptoms for Graves orbitopathy patients. It occurs in moderate-to-severe Graves orbitopathy stages and does not respond well to available anti-inflammatory treatment...
June 13, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29905626/ulnar-nerve-injury-in-pediatric-midshaft-forearm-fractures-a-case-series
#9
Andrew E Federer, Joshua S Murphy, James H Calandruccio, Dennis P Devito, Scott H Kozin, Greg S Slappey, Gary M Lourie
OBJECTIVES: To describe a midshaft forearm fracture pattern that places the ulnar nerve at risk in the pediatric population and provide seven clinical case examples describing the injury pattern and treatment methods. DESIGN: Retrospective observational case series, review of literature, cadaver dissection, and treatment recommendations. SETTING: Multi-institutional, Southeast United States PATIENTS:: Seven pediatric patients (5 male, 2 female) with mean age of 8...
June 4, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29905055/-effect-of-chitosan-porous-scaffolds-combined-with-bone-marrow-mesenchymal-stem-cells-in-repair-of-neurological-deficit-after-traumatic-brain-injury-in-rats
#10
Keke Tan, Xiuxiu Wang, Jun Zhang, Zhigang Zhuang, Tieli Dong
Objective: To investigate the possibility and effect of chitosan porous scaffolds combined with bone marrow mesenchymal stem cells (BMSCs) in repair of neurological deficit after traumatic brain injury (TBI) in rats. Methods: BMSCs were isolated, cultured, and passaged by the method of bone marrow adherent culture. The 3rd generation BMSCs were identified by the CD29 and CD45 surface antigens and marked by 5-bromo-2-deoxyuridine (BrdU). The chitosan porous scaffolds were produced by the method of freeze-drying...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29905051/-new-type-of-sutured-titanium-wire-combined-with-titanium-nail-internal-fixation-for-correction-of-serious-old-medial-canthus-deformity
#11
Ying Zhang, Changhong Zeng, Jun Chen, Bo Guo
Objective: To evaluate the effectiveness of a new type of sutured titanium wire combined with titanium nail internal fixation in correction of serious old medial canthus deformity. Methods: Between March 2012 and June 2015, 18 patients with unilateral serious old medial canthus deformity were treated. There were 14 males and 4 females. The patient's age ranged from 23 to 62 years (mean, 42 years). The causes of deformity included accident injury in 10 cases, boxing injury in 4 cases, sharp device scratching in 3 cases, and animal bite in 1 case...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29905049/-application-of-combined-transverse-upper-gracilis-flap-and-adductor-magnus-perforator-flap-in-breast-reconstruction
#12
Dajiang Song, Zan Li, Xiao Zhou, Yixin Zhang, Xiaowei Peng, Bo Zhou, Chunliu Lü, Wen Peng, Huangxing Mao
Objective: To explore the clinical application of combined transverse upper gracilis flap and adductor magnus perforator flap in breast reconstruction of breast cancer patients after mastectomy. Methods: Between August 2016 and February 2017, the combined transverse upper gracilis flap and adductor magnus perforator flap was used in 12 cases of breast cancer patients who received modified radical surgery for breast reconstruction. All patients were females with the age of 32 to 59 years (mean, 41...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29904803/atypical-cutaneous-presentations-of-sarcoidosis-two-case-reports-and-review-of-the-literature
#13
REVIEW
David L Leverenz, Christopher Henderson, Ankoor Shah
PURPOSE OF REVIEW: The goal of this review is to provide the reader with an updated summary of the cutaneous manifestations of systemic sarcoidosis, with a particular emphasis on the predilection of sarcoidosis for scars, tattoos, and other areas of traumatized skin. RECENT FINDINGS: While the mechanism underlying the propensity for traumatized skin to develop sarcoidosis lesions remains unclear, several theories have been proposed including the idea that cutaneous sarcoidosis represents an exuberant, antigen-driven foreign-body response, as well as the theory that traumatized skin represents an immunocompromised district with altered local immune trafficking and neural signaling...
June 14, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29904432/breast-panniculitis-with-liquefactive-fat-necrosis-a-case-report
#14
Yongfeng Zhang, Xuhua Shi, Yuewu Lu
Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation of the mammary glands as the initial presentation and provided a detailed description of ultrasonography, X-ray, computed tomography, magnetic resonance imaging and other imaging features of breast panniculitis...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29904420/analysis-of-the-efficacy-of-resveratrol-treatment-in-patients-with-scarred-uterus
#15
Huashu Ma, Zongxu Qiao
Scarred uterus is caused by cesarean section surgery, and this condition affects further gestation and delivery in patients. Previous evidence suggested that resveratrol, a polyphenol compound, presents beneficial outcomes for patients with scarred uterus. Therefore, the aim of the present study was to analyze the efficacy of resveratrol in the treatment of patients with scarred uterus. The efficacy of resveratrol in the formation of new vessels and re-epithelialization of the endometrium was analyzed. The present results demonstrated that resveratrol treatment reduced uterus scarring in the majority of patients (87...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29903699/a-putative-role-of-apolipoprotein-l1-polymorphism-in-renal-parenchymal-scarring-following-febrile-urinary-tract-infection-in-nigerian-under-five-children-proposal-for-a-case-control-association-study
#16
Emmanuel Ademola Anigilaje
BACKGROUND: Although urinary tract infection (UTI) resolves with prompt treatment in a majority of children, some children, especially those aged less than 5 years, also develop renal parenchymal scarring (RPS). RPS causes high blood pressure that may lead to severe chronic kidney disease and end-stage renal disease (ESRD). Although the risk of UTI is higher in white children than in black children, it is unknown whether RPS is more common in white children than in black children as data are scarce in this regard...
June 14, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29903601/optimal-skin-regeneration-after-full-thickness-thermal-burn-injury-in-the-spiny-mouse-acomys-cahirinus
#17
Malcolm Maden
The spiny mouse, Acomys cahirinus, shows remarkable regenerative abilities after excisional skin wounding by regrowing hair, sebaceous glands, smooth muscle, skeletal muscle and dermis without scarring. We have asked here whether this same regeneration can be seen after full thickness thermal burn injuries. Using a brass rod thermal injury model we show that in contrast to the lab mouse, Mus musculus, which forms a thick scar covered by a hairless epidermis, the spiny mouse regenerates all the tissues injured - skeletal muscle, dermis, hairs, sebaceous glands such that the skin is externally indistinguishable from its original appearance...
June 11, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29902643/a-rare-case-of-hyperplastic-proximal-esophageal-polyps-with-foveolar-dysplasia
#18
Maham Hayat, Sultan Mahmood, John T Maple
A 62-year-old male with long-standing esophageal reflux underwent endoscopy at an outside institution that reported multiple polypoid lesions in upper esophagus and a small focal area of nodular mucosa at the gastroesophageal junction(GEJ). Biopsies of the proximal esophageal polyps demonstrated hyperplastic mucosa with ulceration, reactive epithelial changes, and focal intestinal metaplasia. Biopsies from the nodular GEJ mucosa were described as Barrett's esophagus with low grade dysplasia. An upper endoscopy performed at our medical center found multiple semi-pedunculated esophageal polyps between 18-24 cm from the incisors (Figure A)...
June 11, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29902584/a-qrs-axis-based-algorithm-to-identify-the-origin-of-scar-related-ventricular-tachycardia-in-an-american-heart-association-17-segment-model
#19
David Andreu, Juan Fernández-Armenta, Juan Acosta, Diego Penela, Beatriz Jáuregui, David Soto-Iglesias, Vladimir Syrovnev, Elena Arbelo, José María Tolosana, Antonio Berruezo
BACKGROUND: Previously proposed algorithms to predict the ventricular tachycardia (VT) exit site have been based on diverse left ventricle (LV) models, but none of them identify the precise region of origin on electroanatomical mapping (EAM). Moreover, no ECG algorithm has been tested to predict the region of origin of scar-related VTs in non-ischemic patients. OBJECTIVE: To validate a simple electrocardiographic algorithm to identify the segment of origin (SgO) VT relative to the 17-segment American Heart Association (AHA) model in patients with structural heart disease (SHD)...
June 11, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29902544/systematic-review-of-the-therapeutic-roles-of-adipose-tissue-in-dermatology
#20
REVIEW
Frances M Walocko, Ariel E Eber, Robert S Kirsner, Evangelos Badiavas, Keyvan Nouri
BACKGROUND: Adipose tissue has classically functioned as a filler in restoring facial volume. Adipose tissue is also rich in stem cells, which may have a role in regenerative medicine. OBJECTIVE: To summarize the literature on the clinical uses of adipose tissue in scarring, wound healing, and hair growth and determine if evidence exists for clinical practice changes in dermatology. METHODS: We utilized the Preferred Reporting Items for Systemic Reviews and Meta-Analysis (PRISMA) to conduct the review...
June 11, 2018: Journal of the American Academy of Dermatology
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