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https://www.readbyqxmd.com/read/28218769/new-world-s-old-disease-cardiac-hydatid-disease-and-surgical-principles
#1
Omer Tanyeli, Yuksel Dereli, Ilker Mercan, Niyazi Gormus, Tahir Yuksek
BACKGROUND: Hydatid cyst is a parasitic disease caused by infection with the Echinococcus granulosus tapeworm larva. It is a major public health problem in endemic regions. Cardiac involvement of the disease is rare. METHODS: Between 1985 and 2015, 12 patients were admitted to our clinic with a possible diagnosis of cardiac hydatid disease. Of these patients, six (50%) were male and six (50%) were female. Mean age of the patients was 42.6 years. RESULTS: The most common location of cardiac hydatid disease was left sided (six patients, 50%)...
February 20, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28212790/the-echinococcoses-diagnosis-clinical-management-and-burden-of-disease
#2
P Kern, A Menezes da Silva, O Akhan, B Müllhaupt, K A Vizcaychipi, C Budke, D A Vuitton
The echinococcoses are chronic, parasitic diseases that are acquired after ingestion of infective taeniid tapeworm eggs from certain species of the genus Echinococcus. Cystic echinococcosis (CE) occurs worldwide, whereas, alveolar echinococcosis (AE) is restricted to the northern hemisphere, and neotropical echinococcosis (NE) has only been identified in Central and South America. Clinical manifestations and disease courses vary profoundly for the different species of Echinococcus. CE presents as small to large cysts, and has commonly been referred to as 'hydatid disease', or 'hydatidosis'...
2017: Advances in Parasitology
https://www.readbyqxmd.com/read/28212398/modelling-the-risk-of-taenia-solium-exposure-from-pork-produced-in-western-kenya
#3
Lian F Thomas, William A de Glanville, Elizabeth A J Cook, Barend M De C Bronsvoort, Ian Handel, Claire N Wamae, Samuel Kariuki, Eric M Fèvre
The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite's life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T...
February 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28208867/osseous-hydatidosis-of-femur-in-a-patient-with-fracture-non-union-an-uncommon-entity
#4
Kiruthiga Kala Gnanasekaran, Anne Jennifer Prabhu, Shyjumon George
Hydatid disease caused by the larval form of the parasitic tapeworm, Echinococcus granulosus, commonly affects the liver and lungs. Bone involvement by Hydatid is extremely uncommon and is reported in 1-3% of cases. It is often a dormant disease, presenting at a late stage with non-specific clinical and radiological findings. Usually they occur as an isolated entity without liver/lung involvement and a clinical suspicion of this disease is not possible. We report a rare case of Hydatid cyst of femur in a 25-year-old female, with unresolving non-union of fracture for five years...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28194292/cystic-echinococcosis-a-case-of-extrahepatic-intra-abdominal-involvement
#5
Patrícia Leitão, André Carvalho, Teresa Fernandes, José Gonçalves
Hydatid disease, or echinococcal disease, is a parasitic infestation caused by the larval stage of the Echinococcus tapeworm and it primarily affects the liver and lung but involvement of other organs is also possible secondary to peritoneal seeding or hematogeneous dissemination. We describe a rare case of extensive abdominal disease, with lesions affecting the liver, peritoneum, and lesser omentum, requiring aggressive surgical intervention. Complementary diagnostic exams were crucial to reach the diagnosis and evaluate the extension of the disease...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28192437/species-dependent-impact-of-helminth-derived-antigens-on-human-macrophages-infected-with-mycobacterium-tuberculosis-direct-effect-on-the-innate-anti-mycobacterial-response
#6
Naomi Aira, Anna-Maria Andersson, Susmita K Singh, Derek M McKay, Robert Blomgran
BACKGROUND: In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is typical of helminth infections. A strong Th2 response has been associated with decreased protection against tuberculosis. PRINCIPAL FINDINGS: We investigated the direct effect of helminth-derived antigens on human macrophages, hypothesizing that helminths would render macrophages less capable of controlling Mtb...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28185895/using-the-small-subunit-of-nuclear-ribosomal-dna-to-reveal-the-phylogenetic-position-of-the-plerocercoid-larvae-of-spirometra-tapeworms
#7
Xi Zhang, Jiang Yang Duan, Zhong Quan Wang, Peng Jiang, Ruo Dan Liu, Jing Cui
Although medically important, the systematics of Spirometra and the taxonomic position of S. erinaceieuropaei remain unclear. In this study, the 18S rDNA gene of S. erinaceieuropaei sparganum from naturally infected frogs caught in 14 geographical locations of China was sequenced. In addition, all available 18S sequences of the family Diphyllobothriidae in the Genbank database were included to reconstruct the phylogeny of diphyllobothriid tapeworms. The secondary structure model of the 18S rDNA was also predicated to further explore the sequence variation...
February 6, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28183336/assessing-the-impact-of-intervention-strategies-against-taenia-solium-cysticercosis-using-the-epicyst-transmission-model
#8
Peter Winskill, Wendy E Harrison, Michael D French, Matthew A Dixon, Bernadette Abela-Ridder, María-Gloria Basáñez
BACKGROUND: The pork tapeworm, Taenia solium, and associated human infections, taeniasis, cysticercosis and neurocysticercosis, are serious public health problems, especially in developing countries. The World Health Organization (WHO) has set goals for having a validated strategy for control and elimination of T. solium taeniasis/cysticercosis by 2015 and interventions scaled-up in selected countries by 2020. Timely achievement of these internationally-endorsed targets requires that the relative benefits and effectiveness of potential interventions be explored rigorously within a quantitative framework...
February 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28139530/neurocysticercosis-diagnostic-problems-current-therapeutic-strategies
#9
REVIEW
Vedantam Rajshekhar
Neurocysticercosis (NCC) is the most common single cause of seizures/epilepsy in India and several other endemic countries throughout the world. It is also the most common parasitic disease of the brain caused by the cestode Taenia solium or pork tapeworm. The diagnosis of NCC and the tapeworm carrier (taeniasis) can be relatively inaccessible and expensive for most of the patients. In spite of the introduction of several new immunological tests, neuroimaging remains the main diagnostic test for NCC. The treatment of NCC is also mired in controversy although, there is emerging evidence that albendazole (a cysticidal drug) may be beneficial for patients by reducing the number of seizures and hastening the resolution of live cysts...
September 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28137629/prostaglandins-e2-and-d2-regulators-of-host-immunity-in-the-model-parasite-diphyllobothrium-dendriticum-an-immunocytochemical-and-biochemical-study
#10
Ivan A Kutyrev, Natalia M Biserova, Daniil N Olennikov, Janetta V Korneva, Olga E Mazur
The spectrum of immunomodulating molecules produced by tapeworms is not yet well understood. The aims of this study, on the tapeworm Diphyllobothrium dendriticum, were: 1) detection and quantification of prostaglandins (PGs) E2 and D2 by high performance liquid chromatography; 2) visualization of PGE2 and PGD2 in specific cells, using methods of immunocytochemistry and confocal laser scanning microscopy; and 3) investigation of the ultrastructure of the cells potentially producing PGE2 and PGD2. The PGE2 immunoreaction (IR) was found in the apical terminals of the frontal glands and sensory organs in the tegument and in small neurons belonging to the main cords and commissures...
January 27, 2017: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/28131363/echinococcus-host-interactions-at-cellular-and-molecular-levels
#11
K Brehm, U Koziol
The potentially lethal zoonotic diseases alveolar and cystic echinococcosis are caused by the metacestode larval stages of the tapeworms Echinococcus multilocularis and Echinococcus granulosus, respectively. In both cases, metacestode growth and proliferation occurs within the inner organs of mammalian hosts, which is associated with complex molecular host-parasite interactions that regulate nutrient uptake by the parasite as well as metacestode persistence and development. Using in vitro cultivation systems for parasite larvae, and informed by recently released, comprehensive genome and transcriptome data for both parasites, these molecular host-parasite interactions have been subject to significant research during recent years...
2017: Advances in Parasitology
https://www.readbyqxmd.com/read/28128348/population-expansion-and-individual-age-affect-endoparasite-richness-and-diversity-in-a-recolonising-large-carnivore-population
#12
Ines Lesniak, Ilja Heckmann, Emanuel Heitlinger, Claudia A Szentiks, Carsten Nowak, Verena Harms, Anne Jarausch, Ilka Reinhardt, Gesa Kluth, Heribert Hofer, Oliver Krone
The recent recolonisation of the Central European lowland (CEL) by the grey wolf (Canis lupus) provides an excellent opportunity to study the effect of founder events on endoparasite diversity. Which role do prey and predator populations play in the re-establishment of endoparasite life cycles? Which intrinsic and extrinsic factors control individual endoparasite diversity in an expanding host population? In 53 individually known CEL wolves sampled in Germany, we revealed a community of four cestode, eight nematode, one trematode and 12 potential Sarcocystis species through molecular genetic techniques...
January 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28118500/leaf-swallowing-and-parasite-expulsion-in-khao-yai-white-handed-gibbons-hylobates-lar-the-first-report-in-an-asian-ape-species
#13
Claudia Barelli, Michael A Huffman
Leaf swallowing behavior, known as a form of self-medication for the control of nematode and tapeworm infection, occurs widely in all the African great apes (Pan troglodytes schweinfurthii, P. t. troglodytes, P. t. verus, P. t. vellerosus, Pan paniscus, Gorilla gorilla graueri), except mountain gorillas. It is also reported to occur in a similar context across a wide array of other animal taxa including, domestic dogs, wolves, brown bears, and civets. Despite long-term research on Asian great and small apes, this is the first report of leaf swallowing in an Asian species, the white-handed gibbon (Hylobates lar) in Khao Yai National Park, central Thailand...
March 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28109802/evidence-that-a-tapeworm-does-not-cause-significant-weight-loss
#14
Cal de Raaff, Smm de Castro, Wf van Tets
No abstract text is available yet for this article.
November 18, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28098540/diphyllobothrium-nihonkaiense-tapeworm-larvae-in-salmon-from-north-america
#15
Roman Kuchta, Mikuláš Oros, Jayde Ferguson, Tomáš Scholz
Diphyllobothriosis is reemerging because of global importation and increased popularity of eating raw fish. We detected Diphyllobothrium nihonkaiense plerocercoids in the musculature of wild pink salmon (Oncorhynchus gorbuscha) from Alaska, USA. Therefore, salmon from the American and Asian Pacific coasts and elsewhere pose potential dangers for persons who eat these fish raw.
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28094779/suppression-of-colitis-by-adoptive-transfer-of-helminth-antigen-treated-dendritic-cells-requires-interleukin-4-receptor-%C3%AE-signaling
#16
C E Matisz, B Faz-López, E Thomson, A Al Rajabi, F Lopes, L I Terrazas, A Wang, K A Sharkey, D M McKay
Infection with helminth parasites has been explored as a treatment for autoimmune and inflammatory diseases. As helminth antigens have potent immunomodulation properties capable of inducing regulatory programs in a variety of cell types, transferring cells treated with helminth antigens represents a novel extension to helminth therapy. Previous work determined that transfer of bone marrow-derived dendritic cells (DC) pulsed with a crude extract of the tapeworm Hymenolepis diminuta (HD) can suppress colitis in recipient mice...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28091386/prevalence-of-infection-with-the-larval-form-of-the-cestode-parasite-taenia-saginata-in-cattle-in-northwest-iran-and-its-zoonotic-importance
#17
Mohammad Mirzaei, Ahmad Nematolahi, Javad Ashrafihelan, Hadi Rezaei
OBJECTIVE: Bovine cysticercosis is a cattle infection caused by a tapeworm, Taenia saginata. While the condition is relatively innocuous, the parasite infects the small intestine of humans in its mature stage and causes a few specific symptoms such as abdominal pain and nausea. METHODS: Between February 2013 and February 2014, a total of 640 cattle were randomly selected from all the cattle sent to the abattoir, and some internal organs and skeletal muscles of these cattle were inspected...
December 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28091347/changes-in-the-seroprevalence-of-cysticercosis-in-suspected-patients-in-chandigarh-india-between-1998-and-2014-analysis-of-17-years-of-data
#18
L J Robertson, H Joshi, K S Utaaker, A Kumar, S Chaudhary, K Goyal, R Sehgal
Changes in seroprevalence of cysticercosis diagnosed in Chandigarh, India between 1998 and 2014 were investigated by extraction and analysis of data from records held at the Postgraduate Institute of Medical Education and Research in Chandigarh. Among the total number of samples for which cysticercosis had been suspected during this period (N = 9650), 1716 (17·8%) were seropositive. Adults were more likely to be seropositive than children, and women were more likely to be seropositive than men. In addition to there being fewer patients with suspicion of cysticercosis over the data analysis period, the proportion of patients seropositive also reduced significantly...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28081501/isolation-characterization-using-lc-esi-qtof-nmr-and-in-vitro-cytotoxicity-assay-of-niclosamide-forced-degradation-products
#19
Johnsirani P, Vishnuvardhan Ch, Lingesh A, Naidu V G M, Naveen Ch, Satheeshkumar N
The present study describes the isolation, characterization and in vitro cytotoxic effect of all forced degradation products of niclosamide (NCM) an anthelmintic class of drug used specifically to treat tapeworms. NCM was subjected to forced degradation involving hydrolysis (acidic, alkaline and neutral), oxidative, photolysis and thermal stress, as per ICH (Q1A (R2)) suggested conditions. The drug under hydrolytic (acidic and basic) conditions showed extensive degradation, while it was stable under neutral hydrolytic, oxidative, photolytic and thermal stress conditions...
March 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28077749/survey-of-obstetrician-gynecologists-in-the-united-states-about-taeniasis-and-cysticercosis
#20
Rebecca L Hall, Britta Anderson, Jay Schulkin, Paul T Cantey, Susan P Montgomery, Jeffrey L Jones
An estimated 50 million persons worldwide are infected with cysticerci, the larval forms of the Taenia solium tapeworm. Neurocysticercosis can cause seizures, epilepsy, and hydrocephalus, and fatal cases have been reported in the United States in immigrants and in travelers returning from endemic countries. Pregnant women with symptomatic neurocysticercosis present treatment challenges, whereas those with the adult tapeworm infection (i.e., taeniasis) can put their infants and other family members, as well as obstetrician-gynecologists and their staff, at risk for cysticercosis...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
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