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https://www.readbyqxmd.com/read/29782829/global-phylogeography-and-genetic-diversity-of-the-zoonotic-tapeworm-echinococcus-granulosus-sensu-stricto-genotype-g11
#1
Liina Kinkar, Teivi Laurimäe, Gerardo Acosta-Jamett, Vanessa Andresiuk, Ibrahim Balkaya, Adriano Casulli, Robin B Gasser, Joke van der Giessen, Luis Miguel González, Karen L Haag, Houria Zait, Malik Irshadullah, Abdul Jabbar, David J Jenkins, Eshrat Beigom Kia, Maria Teresa Manfredi, Hossein Mirhendi, Selim M'rad, Mohammad Rostami-Nejad, Myriam Oudni-M'rad, Nora Beatriz Pierangeli, Francisco Ponce-Gordo, Steffen Rehbein, Mitra Sharbatkhori, Sami Simsek, Silvia Viviana Soriano, Hein Sprong, Viliam Šnábel, Gérald Umhang, Antonio Varcasia, Urmas Saarma
Echinococcus granulosus sensu stricto (s.s.) is the major cause of human cystic echinococcosis worldwide and is listed among the most severe parasitic diseases of humans. To date, numerous studies have investigated the genetic diversity and population structure of E. granulosus s.s. in various geographic regions. However, there has been no global study. Recently, using mitochondrial DNA, it was shown that E. granulosus s.s. G1 and G3 are distinct genotypes, but a larger dataset is required to confirm the distinction of these genotypes...
May 18, 2018: International Journal for Parasitology
https://www.readbyqxmd.com/read/29781421/molecular-phylogeny-based-on-six-nuclear-genes-suggests-that-echinococcus-granulosus-sensu-lato-genotypes-g6-g7-and-g8-g10-can-be-regarded-as-two-distinct-species
#2
Teivi Laurimäe, Liina Kinkar, Epp Moks, Thomas Romig, Rihab A Omer, Adriano Casulli, Gérald Umhang, Guna Bagrade, Malik Irshadullah, Mitra Sharbatkhori, Hossein Mirhendi, Francisco Ponce-Gordo, Silvia V Soriano, Antonio Varcasia, Mohammad Rostami-Nejad, Vanessa Andresiuk, Urmas Saarma
Tapeworms of the species complex of Echinococcus granulosus sensu lato (s. l.) are the cause of a severe zoonotic disease - cystic echinococcosis, which is listed among the most severe parasitic diseases in humans and is prioritized by the World Health Organization. A stable taxonomy of E. granulosus s. l. is essential to the medical and veterinary communities for accurate and effective communication of the role of different species in this complex on human and animal health. E. granulosus s. l. displays high genetic diversity and has been divided into different species and genotypes...
May 21, 2018: Parasitology
https://www.readbyqxmd.com/read/29780006/investigation-of-the-applicability-of-a-rapid-diagnosis-test-in-the-diagnosis-of-cystic-echinococcosis
#3
Sema Ertuğ, Serçin Özlem Çalışkan, Erdoğan Malatyalı, Hatice Ertabaklar
OBJECTIVE: Echinococcus granulosus, the etiological agent of cystic echinococcosis (CE) in humans and livestock, is a widely distributed zoonotic pathogen tapeworm. The infection is transmitted to humans by the ingestion of E. granulosus eggs released in the feces of definitive hosts such as dogs. The larval stage of the parasite develops a slowly enlarging cyst in the visceral organs, particularly in the liver and/or lung. The aim of the present study was to evaluate the diagnostic value of an immunochromatographic test (ICT) for CE...
May 21, 2018: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29774855/molecular-diagnosis-of-taenia-saginata-tapeworm-infection-in-2-schoolchildren-myanmar
#4
Eun Jeong Won, Bong-Kwang Jung, Hyemi Song, Mi-Seon Kim, Hyun-Seung Kim, Keon Hoon Lee, Min-Jae Kim, Myung Geun Shin, Jong Hee Shin, Soon-Pal Suh, Sung-Jong Hong, Woon-Mok Sohn, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
Taenia saginata is the most common human tapeworm worldwide but has been unknown in Myanmar. In 2017, fecal examination in Yangon, Myanmar, revealed eggs of Taenia species in 2 children from a monastic school. Several proglottids expelled after medication with praziquantel were morphologically and molecularly confirmed to be T. saginata tapeworms.
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29774294/seroprevalence-and-awareness-of-porcine-cysticercosis-across-different-pig-production-systems-in-south-central-cambodia
#5
Aderosoye Adenuga, Ana Mateus, Chhay Ty, Khieu Borin, Davun Holl, Sorn San, Victoria Duggan, Madeleine Clark, Gavin J D Smith, Richard Coker, Andrew Vaughn, James W Rudge
Background: Taeniasis/cysticercosis, caused by the pork tapeworm Taenia solium , represents an important public health and economic burden in endemic countries. However, there is a paucity of data on infection among pigs in many parts of Southeast Asia, particularly Cambodia. We aimed to estimate seroprevalence of porcine cysticercosis, and investigate husbandary practices and knowledge of the disease among livestock workers, across different pig sector units in south-central Cambodia...
February 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29766407/an-annotated-list-and-molecular-data-on-larvae-of-gryporhynchid-tapeworms-cestoda-cyclophyllidea-from-freshwater-fishes-in-africa
#6
Tomáš Scholz, Sareh Tavakol, Lucie Uhrová, Jan Brabec, Iva Přikrylová, Šárka Mašová, Andrea Šimková, Ali Halajian, Wilmien J Luus-Powell
An annotated list of larvae (metacestodes) of gryporhynchid tapeworms (Cestoda: Cyclophyllidea) from freshwater fishes in Africa is provided with numerous new host and geographical records. Newly collected materials from Burundi, Democratic Republic of the Congo, Kenya, Madagascar, Namibia, Senegal, South Africa, Sudan and Zimbabwe practically double the total number of species reported from African fish so far. We confirm the occurrence of 16 species (five unidentified to the species level and most likely representing new taxa) belonging to the genera Amirthalingamia Bray, 1974 (1 species), Cyclustera Fuhrmann, 1901 (2 species), Dendrouterina Fuhrmann, 1912 (1 species), Neogryporhynchus Baer & Bona, 1960 (1 species), Paradilepis Hsü, 1935 (4 species), Parvitaenia Burt, 1940 (5 species), and Valipora Linton, 1927 (2 species)...
May 16, 2018: Systematic Parasitology
https://www.readbyqxmd.com/read/29752648/human-cystic-echinococcosis-in-hungary-2000-2014-a-retrospective-case-series-analysis-from-a-single-center-study
#7
Balázs Dezsényi, Áron Somorácz, József Danka, István Kucsera, Thomas F E Barth, Adriano Casulli
PURPOSE: Cystic echinococcosis (CE) is a parasitic disease caused by the tapeworm Echinococcus granulosus sensu lato. Although in Hungary the disease is listed among reportable infections, inadequacies in the reporting practice of CE by clinicians and pathologists have resulted in underscoring of this disease. The aim of this study was to describe the epidemiological and clinical characteristics of CE in Hungary using a datasource other than the official records that are based mainly on serological data...
May 11, 2018: Infection
https://www.readbyqxmd.com/read/29720136/prevalence-and-predictors-of-under-nutrition-among-school-children-in-a-rural-south-eastern-nigerian-community-a-cross-sectional-study
#8
Rufina N B Ayogu, Ifeoma C Afiaenyi, Edith U Madukwe, Elizabeth A Udenta
BACKGROUND: School children in developing countries like Nigeria are faced with numerous nutrition and health problems. Lack of functional school health and nutrition programmes in Enugu state, Nigeria may be associated with dearth of data on associated factors. Identifying these factors could inform the design and implementation of school-based programmes aimed at ameliorating these problems. METHODS: A cross sectional survey involving 450 primary and secondary school children aged 6-15 years was conducted in Ede-Oballa, a rural community in Enugu state, South-eastern Nigeria...
May 2, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29716880/report-an-ex-vivo-up-take-of-levamisole-molecules-by-cestode-monezia-expensa-of-goat-capra-hirsa-and-its-detection-through-rp-hplc
#9
Muhammad Mazhar Ayaz, Muhammad Sajid, Sanjota Nirmal Das, Muhammad Hanif
Detection of various molecules of drugs remained a prime issue especially in tissues of animals, humans and in their target parasites. The cestode/tapeworms pose a dilemma because of their weird body composition and uptake pattern of nutrients and medicines especially through absorption by tegument. We selected levamisole; thought to be potent antiparasitic/ani-cestodal drug. The uptake of levamisole (LEV) through cestodeal tissues is studied through HPCL in this paper. High performance liquid chromatography technique has been utilized to know the uptake of levamisole in tissues of cestodes of Goat (Monezia expensa) in small ruminants...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29692513/an-unusual-case-of-urinary-sparganosis-in-the-indian-subcontinent
#10
Bajpai Trupti, Nandedkar Shirish, Pandey Maneesha, Agrawal Santosh
Spirometra is a genus of pseudophyllidean cestode that reproduces in canines and felines but can cause pathology in humans. When humans harbour plerocercoids of these tapeworms outside the intestine, it can cause sparganosis. We report a case of urinary sparganosis in a young woman, passing multiple spargana worms in her urine. The worm was identified as the plerocercoid larvae of Spirometra spp., and the case was managed successfully.
April 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29689834/towards-a-robust-systematic-baseline-of-neotropical-fish-tapeworms-cestoda-proteocephalidae-amended-diagnoses-of-two-genera-from-the-redtail-catfish-phractocephalus-hemioliopterus
#11
Philippe V Alves, Alain de Chambrier, JosÉ L Luque, TomÁŠ Scholz
Species of two monotypic genera, Ephedrocephalus Diesing, 1850 and Zygobothrium Diesing, 1850 (Cestoda: Proteocephalidae), parasites of one of the most basal members of the catfish family Pimelodidae, the redtail catfish, Phractocephalus hemioliopterus, in the Neotropical Region, are redescribed based on the evaluation of type specimens and newly collected material. Generic diagnoses are amended to provide a robust baseline for the future re-arrangement of the classification of proteocephalid cestodes. Ephedrocephalus is typified by the medullary position of the ovary and uterus, the cortical distribution of vitelline follicles (dispersed throughout almost the entire ventral cortex) and the testes in one dorsal field...
January 12, 2018: Zootaxa
https://www.readbyqxmd.com/read/29673434/diphyllobothriasis-in-a-u-s-military-aviator
#12
Stephen D Kasteler
BACKGROUND: Diphyllobothriasis is estimated to afflict 10-20 million people worldwide; however, this is the first case reported in a United States military aviator. Among the largest parasites of humans, the "fish tapeworm" grows from 2-15 m in length, can live >20 yr in the intestines, and is contracted through consumption of uncooked, unfrozen freshwater or anadromous fish species. CASE REPORT: A 32-yr-old male F-22 pilot presented with mild stomach cramping, bloating, nausea, and intermittent loose stools...
May 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29660815/scaling-down-a-deworming-program-among-school-age-children-after-a-thirty-year-successful-intervention-in-the-bolivian-chaco
#13
Michele Spinicci, Fabio Macchioni, David Rojo, Herlan Gamboa, Ana Liz Villagrán, Yolanda Vallejos, Marianne Strohmeyer, Mimmo Roselli, Simona Gabrielli, Gabriella Cancrini, Joaquín Monasterio, Paul Castellanos, Grover Adolfo Paredes, Sdenka Maury, Adolfo Zárate, Rodolfo Rocabado, Piero Olliaro, Antonio Montresor, Alessandro Bartoloni
OBJECTIVE: Preventive chemotherapy is the WHO-recommended control method for soil-transmitted helminthiases. In the Bolivian Chaco, 6-monthly single-dose mebendazole delivery to school-age children achieved a dramatic decrease in soil-transmitted helminthiases prevalence between 1987 and 2013. Consequently, in September 2016, preventive chemotherapy delivery was interrupted in 9 rural communities. In compliance with WHO recommendations, we intensified surveillance to monitor soil-transmitted helminthiases prevalence and detect potential changes that would require interventions...
April 16, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29625098/evaluation-of-kinase-inhibitors-nilotinib-and-everolimus-against-alveolar-echinococcosis-in-vitro-and-in-a-mouse-model
#14
Deborah E Joekel, Britta Lundström-Stadelmann, Beat Müllhaupt, Andrew Hemphill, Peter Deplazes
Infection with the larval stage (metacestode) of the fox tapeworm Echinococcus multilocularis leads to a primary hepatic disease referred to as alveolar echinococcosis (AE). The progressive disease can be lethal if untreated. In cases where complete parasite resection by surgery is not feasible, the current treatment regimens of AE consist of chemotherapy with the parasitostatic benzimidazoles albendazole or mebendazole over decades. Kinase-inhibitors currently administered in various cancer treatments are of increasing interest also as anti-parasitic drugs due to previous promising in vitro results...
April 3, 2018: Experimental Parasitology
https://www.readbyqxmd.com/read/29621234/clinical-cysticercosis-epidemiology-in-spain-based-on-the-hospital-discharge-database-what-s-new
#15
Zaida Herrador, Amalia Fernandez-Martinez, Agustín Benito, Rogelio Lopez-Velez
BACKGROUND: Cysticercosis (CC) is a tissue infection caused by the larval cysts of the pork tapeworm Taenia solium. It is usually acquired by eating contaminated food or drinking water. CC Cysts can develop in the muscles, the eyes, the brain, and/or the spinal cord. T. solium is found worldwide, but its prevalence has decreased in developed countries due to stricter meat inspection and better hygiene and sanitation. Nevertheless, CC is still a leading cause of seizures and epilepsy. In Spain, The disease is not nationally reportable and data on CC infected animals are also missing, despite the European Directive 2003/99/EC...
April 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29603892/niclosamide-a-drug-with-many-re-purposes
#16
Hachemi Kadri, Olivia A Lambourne, Youcef Mehellou
Niclosamide is an anthelmintic drug that has mainly been used for over 50 years to treat tapeworm infections. However, with the increase in drug repurposing initiatives, niclosamide has emerged as a true hit in many screens against various diseases. Indeed, from being an anthelmintic drug, it has now shown potential in treating Parkinson's disease, diabetes, viral and microbial infections as well as various cancers. Such diverse pharmacological activities are a result of niclosamide's ability to uncouple mitochondrial phosphorylation and modulate a selection of signaling pathways, such as Wnt/β-catenin, mTOR and JAK/STAT3, which are implicated many diseases...
March 30, 2018: ChemMedChem
https://www.readbyqxmd.com/read/29595013/-multidisciplinary-management-of-alveolar-echinococcosis-echino-liege-working-group
#17
A Cambier, J B Giot, P Leonard, N Bletard, P Meunier, R Hustinx, J Delwaide, N Meurisse, P Honore, B Losson, M P Hayette, O Detry
Alveolar echinococcosis is a zoonotic disease due to the tapeworm Echinococcus multilocularis. The definitive host is the red fox. Until recently, Belgium was considered a country at very low risk for alveolar echinococcosis. However, recent studies carried out in southern Belgium have revealed, through post-mortem examination, high prevalences (up to 62 %) in foxes. Cats and dogs can act as definitive hosts. Human are accidentally infected by ingestion of food contaminated by the feces. After a long incubation period, invasive hepatic lesions may appear, as well as extra-hepatic lesions...
March 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29594121/-echinococcus-granulosus-cure-for-cancer-revisited
#18
REVIEW
Shiwanthi L Ranasinghe, Donald P McManus
Whereas a number of parasites are well recognized risk factors for a number of different cancers in mammalian hosts, there is limited information on the ability of parasitic organisms to induce anticancer effects. There are conflicting reports that echinococcosis, caused by the canine tapeworm Echinococcus granulosus , can decrease or increase cancer risk. This review considers both indirect anticancer effects as the result of adaptive immunity generated against certain echinococcal antigens and the direct effect of molecules released by E ...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29580663/asian-fish-tapeworm-the-most-successful-invasive-parasite-in-freshwaters
#19
REVIEW
Roman Kuchta, Anindo Choudhury, Tomáš Scholz
The Asian fish tapeworm (AFT), Schyzocotyle acheilognathi, is a notorious and highly successful invasive parasite reported in a wide spectrum of freshwater fishes, and new reports of its spread continue to emerge. To date, no thorough review of its worldwide distribution and host associations is available. In the present work, we collected information from 651 articles up until 2017, from which we updated the number of the hosts to 312 fish species and 11 non-fish species, which is quite unusual among helminths...
March 23, 2018: Trends in Parasitology
https://www.readbyqxmd.com/read/29580090/helminths-of-european-smelt-osmerus-eperlanus-linnaeus-1758-in-lake-ha%C3%A5-cza-and-the-vistula-lagoon-with-special-regard-to-their-zoonotic-threats
#20
Janina Dziekońska-Rynko, Katarzyna Mierzejewska, Katarzyna Kubiak, Martyna Rydzewska, Piotr Hliwa
Reports published in recent years on the increased risk in the Baltic Sea of fish infection with larvae of nematodes potentially pathogenic to humans have prompted a study of European smelt Osmerus eperlanus with respect to the presence of these parasites in the Vistula Lagoon. Additionally, samples of this fish from Lake Hańcza were comparatively considered. The body cavity, the surface of internal organs, the alimentary tract and the swimbladder of fish from two environmentally different water bodies were taken into account in the analysis...
March 2018: Acta Veterinaria Hungarica
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