Yuqian Long, Zhiqiang Qin, Minlan Duan, Shizhu Li, Xiaoqiu Wu, Wei Lin, Jianglin Li, Zilong Zhao, Jing Liu, Dehui Xiong, Yi Huang, Xiaoxiao Hu, Chao Yang, Mao Ye, Weihong Tan
Schistosomiasis is a major parasitic disease caused by blood flukes of the genus Schistosoma. Several million people all over the world are estimated to suffer from severe morbidity as a consequence of schistosomiasis. The worm's eggs, which cause the symptoms of schistosomiasis, are generally used to diagnose the disease. In this study, we employed egg-based systematic evolution of ligands by exponential enrichment (egg-SELEX) and identified a panel of ssDNA aptamers specifically binding to eggs derived from S...
April 28, 2016: Scientific Reports