Michael A Cook, Daniel Pallant, Linda Ejim, Arlene D Sutherland, Xiaodong Wang, Jarrod W Johnson, Susan McCusker, Xuefei Chen, Maya George, Sommer Chou, Kalinka Koteva, Wenliang Wang, Christian Hobson, Dirk Hackenberger, Nicholas Waglechner, Obie Ejim, Tracey Campbell, Ricardo Medina, Lesley T MacNeil, Gerard D Wright
Microbial natural products are specialized metabolites that are sources of many bioactive compounds including antibiotics, antifungals, antiparasitics, anticancer agents, and probes of biology. The assembly of libraries of producers of natural products has traditionally been the province of the pharmaceutical industry. This sector has gathered significant historical collections of bacteria and fungi to identify new drug leads with outstanding outcomes-upwards of 60% of drug scaffolds originate from such libraries...
December 5, 2023: Journal of Industrial Microbiology & Biotechnology