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Global burden of injury

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https://www.readbyqxmd.com/read/29138652/trauma-a-major-cause-of-death-among-surgical-inpatients-of-a-nigerian-tertiary-hospital
#1
Onyeanunam Ngozi Ekeke, Kelechi Emmanuel Okonta
Introduction: Trauma presents a significant global health burden. Death resulting from trauma remains high in low income countries despite a steady decrease in developed countries. Analysis of the pattern of death will enable intervention to reduce these deaths from trauma in developing countries. This study aims to present the pattern of trauma-related deaths in the surgical wards of University of Port Harcourt Teaching Hospital (UPTH). Methods: This was a retrospective study of all patients who died from trauma during admission into the surgical wards of UPTH from 2007 to 2012...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29128246/long-term-exposure-to-ambient-pm2-5-associated-with-fall-related-injury-in-six-low-and-middle-income-countries
#2
Yanfei Guo, Hualiang Lin, Yan Shi, Yang Zheng, Xing Li, Jianpeng Xiao, Tao Liu, Weilin Zeng, Michael G Vaughn, Lenise A Cummings-Vaughn, Erik J Nelson, Zhengmin Min Qian, Wenjun Ma, Fan Wu
Exposure to ambient air pollution has been linked with adverse health outcomes of the circulatory and nervous systems. Given that falls are closely related to circulatory and nervous health, we hypothesize that air pollution may adversely affect fall-related injury. We employed Wave 1 data from 36,662 participants aged ≥50 years in WHO's Study on Global AGEing and Adult Health in six low- and middle-income countries. Ambient annual concentration of PM2.5 was estimated using satellite data. A three-level logistic regression model was applied to examine the long-term association between ambient PM2...
November 8, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29119221/preparing-japanese-surgeons-for-potential-mass-casualty-situations-will-require-innovative-and-systematic-programs
#3
H Uchino, V Y Kong, J L Bruce, G V Oosthuizen, W Bekker, G L Laing, D L Clarke
INTRODUCTION: The ongoing state of global geo-political instability means that it is prudent to prepare civilian surgeons to manage major military-type trauma. Japan has enjoyed a prolonged period of peace and consequently it is unlikely that surgeons will have been exposed to a sufficient volume of cases. This study reviews the state of trauma training and preparedness in Japan and reviews the trauma workload of a major Japanese emergency medical center and compared with a major South African trauma center with the intention of quantifying and comparing the time needed to gain adequate exposure to major trauma at the two centers...
November 8, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29112145/pattern-of-road-traffic-injuries-in-rural-bangladesh-burden-estimates-and-risk-factors
#4
Md Kamran Ul Baset, Aminur Rahman, Olakunle Alonge, Priyanka Agrawal, Shirin Wadhwaniya, Fazlur Rahman
Globally, road traffic injury (RTI) causes 1.3 million deaths annually. Almost 90% of all RTI deaths occur in low- and middle-income countries. RTI is one of the leading causes of death in Bangladesh; the World Health Organization estimated that it kills over 21,000 people in the country annually. This study describes the current magnitude and risk factors of RTI for different age groups in rural Bangladesh. A household census was carried out in 51 unions of seven sub-districts situated in the north and central part of Bangladesh between June and November 2013, covering 1...
November 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29110998/total-small-vessel-disease-burden-and-brain-network-efficiency-in-cerebral-amyloid-angiopathy
#5
Raffaella Valenti, Yael D Reijmer, Andreas Charidimou, Gregoire Boulouis, Sergi Ramirez Martinez, Li Xiong, Panagiotis Fotiadis, Michael Jessel, Alison Ayres, Grace Riley, Leonardo Pantoni, M Edip Gurol, Steven M Greenberg, Anand Viswanathan
BACKGROUND: Cerebral amyloid angiopathy (CAA) is associated with hemorrhagic and nonhemorrhagic markers small vessel disease (SVD). A composite score to quantify the total burden of SVD on MRI specifically for CAA patients was recently developed. Brain network alterations related to individual MRI markers of SVD in CAA were demonstrated. OBJECTIVES: Considering diffusion based network measures sensitive to detect different relevant SVD-related brain injury, we investigated if increased overall SVD injury on MRI corresponds to worse global brain connectivity in CAA...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29107825/atrazine-induced-environmental-nephrosis-was-mitigated-by-lycopene-via-modulating-nuclear-xenobiotic-receptors-mediated-response
#6
Jun Xia, Jia Lin, Xue-Nan Li, Cong Zhang, Nan Li, Zheng-Hai Du, Yan-Hua Li, Jin-Long Li
The burden and morbidity of environmental nephrosis is increasing globally. Atrazine (ATR) and degradation products in the environment are considered key determinants of nephrosis. However, the lack of highly effective treatments for environmental nephrosis creates an urgent need to better understand the preventive strategies and mechanisms. This study aimed to highlight the mechanism of ATR-induced environmental nephrosis and the chemoprotective potential of lycopene (LYC) against the renal injury and nephrosis...
September 21, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29060975/-disease-burden-of-injuries-in-children-aged-0-14-year-old-in-1990-and-2013-in-china
#7
P P Ye, Y Jin, Y L Er, X Deng, Y Wang, X Gao, L L Duan, L H Wang
Objective: To analyze the disease burden of injuries in Chinese children aged between 0-14-year-old, in 1990 and 2013. Methods: Data derived from the Global Burden of Disease 2013 was used to analyze the disease burden of injuries among children aged between 0-14-year-old in each province of China, using relevant indicators including mortality and the rate on disability-adjusted life years (DALY). Results: In 2013, the number of deaths, rates on mortality and DALY caused by injuries in children aged between 0-14-year-old were 73 766, 29...
October 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29060972/-disease-burden-on-road-injury-in-the-chinese-population-in-1990-and-2013
#8
Y Wang, P P Ye, Y Jin, Y L Er, X Deng, X Gao, C R Ji, L Yang, W Wang, L L Duan, L H Wang
Objective: To explore the disease burden of road injuries in China. Methods: The results of Global Burden of Disease 2013 including death rate, disability-adjusted of life years (DALY), years of life lost due to premature mortality (YLL), years lived with disability (YLD), were used to describe the burden caused by road injuries in 2013 and the trends from 1990 to 2013, in China. Results: In 2013, there were 313 676 deaths caused by traffic accidents in China. Death rate, rates on DALY, YLL and YLD were 22...
October 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29060970/-disease-burden-on-drowning-in-the-chinese-population-in-1990-and-2013
#9
X Deng, Y Jin, P P Ye, L H Wang, L L Duan
Objective: To comprehensively analyze the disease burden of drowning in the Chinese population both at the national and provincial levels in 1990 and 2013, to provide reference for the development of strategies regarding drowning prevention. Methods: Both methods related to unified measurement framework and standardized estimation on Global Burden of Disease in 2013, were used. Data on deaths caused by injuries were from the following sources which include: Disease Surveillance Points, the National Maternal and Child Health Surveillance Network, the Death Registration Reporting System of Chinese Center for Disease Control and Prevention, Death Registration System and death information from Macau and Hong Kong areas of China...
October 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29048337/paid-sick-leave-and-risks-of-all-cause-and-cause-specific-mortality-among-adult-workers-in-the-usa
#10
Daniel Kim
Background: The USA is one of only a few advanced economies globally that does not guarantee its workers paid sick leave. While there are plausible reasons why paid sick leave may be linked to mortality, little is known empirically about this association. Methods: In a pooled USA nationally-representative longitudinal sample of 57,323 working adults aged 18-85 years from the National Health Interview Surveys 2000-2002, paid sick leave was examined as a predictor of all-cause and cause-specific mortality. Multivariate Cox proportional hazards models were used to estimate the impact of paid sick leave on mortality...
October 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29042341/pain-self-management-for-veterans-development-and-pilot-test-of-a-stage-based-mobile-optimized-intervention
#11
Sara S Johnson, Deborah A Levesque, Lynne E Broderick, Dustin G Bailey, Robert D Kerns
BACKGROUND: Chronic pain is a significant public health burden affecting more Americans than cardiovascular disease, diabetes, and cancer combined. Veterans are disproportionately affected by chronic pain. Among previously deployed soldiers and veterans, the prevalence of chronic pain is estimated between 44% and 60%. OBJECTIVE: The objective of this research was to develop and pilot-test Health eRide: Your Journey to Managing Pain, a mobile pain self-management program for chronic musculoskeletal pain for veterans...
October 17, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29040423/title-therapeutic-strategies-utilising-sdf-1%C3%AE-in-ischaemic-cardiomyopathy
#12
Oliver J Ziff, Daniel I Bromage, Derek M Yellon, Sean M Davidson
Heart failure is rapidly increasing in prevalence and will redraw the global landscape for cardiovascular health. Alleviating and repairing cardiac injury associated with myocardial infarction (MI) is key to improving this burden. Homing signals mobilise and recruit stem cells to the ischaemic myocardium where they exert beneficial paracrine effects. The chemoattractant cytokine SDF-1α and its associated receptor CXCR4 are upregulated after MI and appear to be important in this context. Activation of CXCR4 promotes both cardiomyocyte survival and stem cell migration towards the infarcted myocardium...
October 13, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/29036993/-study-on-the-disease-burden-of-chinese-adolescent-in-2015
#13
R B Xu, D Y Jin, Y Song, X J Wang, Y H Dong, Z G Yang, Y J Chen, J Ma
Objective: To discuss the main causes and risk factors of disability and death among current Chinese adolescents. Methods: Subnational data of China from Global Burden of Disease Study 2015 (GBD 2015) was used to rank the causes and risk factors leading to death and disability adjusted life years (DALY) in Chinese adolescents aged between 10 and 19 years old, and thereby to analyze the main cauese and risk factors of death and DALY among Chinese adolescents in different genders. Results: In 2015, among Chinese adolescents aged 10-19 years old, the total DALY was 13 million 490 thousand years, and the total number of deaths was 63 258 cases...
October 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29026474/using-growth-mixture-modeling-for-clustering-asian-and-north-african-countries-on-the-road-injury-death-trend-1990-2010
#14
Maryam Salari, Anoshirvan Kazemnejad, Farid Zayeri
OBJECTIVES: The physical injuries and financial implications as a result of road accidents have serious economic, cultural, and social effects. We conducted this study to determine any changes in the trend of road-accident-related deaths in Asian and North African countries from 1990 to 2010. METHODS: The current study was carried out using data from the Global Burden of Disease database. First, the process was assessed using the growth curve divided into six regions...
September 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/29025826/patient-characteristics-of-the-accident-and-emergency-department-of-kenyatta-national-hospital-nairobi-kenya-a-cross-sectional-prospective-analysis
#15
Justin Guy Myers, Katherine M Hunold, Karen Ekernas, Ali Wangara, Alice Maingi, Vincent Mutiso, Stephen Dunlop, Ian B K Martin
BACKGROUND: Resource-limited settings are increasingly experiencing a 'triple burden' of disease, composed of trauma, non-communicable diseases (NCDs) and known communicable disease patterns. However, the epidemiology of acute and emergency care is not well characterised and this limits efforts to further develop emergency care capacity. OBJECTIVE: To define the burden of disease by describing the patient population presenting to the Accident and Emergency Department (A&E) at Kenyatta National Hospital (KNH) in Kenya...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29018914/the-effect-of-a-surgery-residency-program-and-enhanced-educational-activities-on-trauma-mortality-in-sub-saharan-africa
#16
Joana Grudziak, Jared Gallaher, Leonard Banza, Bruce Cairns, Carlos Varela, Sven Young, Anthony Charles
INTRODUCTION: To address the need for more surgical providers in low-resource settings, a collaboration to create a surgical residency-training program for local Malawian physicians was established in 2009. This study sought to describe the short-term independent effect of a surgical residency program on trauma mortality at a tertiary trauma center in sub-Saharan Africa. METHODS: We conducted a retrospective analysis of all patients recorded in the trauma surveillance registry of Kamuzu Central Hospital in Lilongwe, Malawi, from 2009 (three residents) through 2014 (11 residents)...
December 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28991898/insights-and-efforts-to-control-rabies-in-zambia-evaluation-of-determinants-and-barriers-to-dog-vaccination-in-nyimba-district
#17
Carolyn Patricia Mulipukwa, Boyd Mudenda, Allan Rabson Mbewe
BACKGROUND: The current rabies control strategy in Zambia is based on dog vaccination, dog population control and dog movement restrictions. In Nyimba district of Zambia, dog vaccination coverage is low but the incidence of dog bites is high which places the community at risk of rabies infection. The renewed global interest eliminating rabies in developing countries has spurred interest to identify determinants and barriers of dog vaccination in an effort to reduce the overall disease burden...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28982252/self-awareness-four-years-after-severe-traumatic-brain-injury-discordance-between-the-patient-s-and-relative-s-complaints-results-from-the-paris-tbi-study
#18
Camille Chesnel, Claire Jourdan, Eleonore Bayen, Idir Ghout, Emmanuelle Darnoux, Sylvie Azerad, James Charanton, Philippe Aegerter, Pascale Pradat-Diehl, Alexis Ruet, Philippe Azouvi, Claire Vallat-Azouvi
OBJECTIVE: To evaluate the patient's awareness of his or her difficulties in the chronic phase of severe traumatic brain injury (TBI) and to determine the factors related to poor awareness. DESIGN/SETTING/SUBJECTS: This study was part of a larger prospective inception cohort study of patients with severe TBI in the Parisian region (PariS-TBI study). Intervention/Main measures: Evaluation was carried out at four years and included the Brain Injury Complaint Questionnaire (BICoQ) completed by the patient and his or her relative as well as the evaluation of impairments, disability and quality of life...
October 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28965750/emerging-role-of-extracellular-vesicles-in-musculoskeletal-diseases
#19
REVIEW
Cameron Murphy, Joseph Withrow, Monte Hunter, Yutao Liu, Yao Liang Tang, Sadanand Fulzele, Mark W Hamrick
Research into the biology of extracellular vesicles (EVs), including exosomes and microvesicles, has expanded significantly with advances in EV isolation techniques, a better understanding of the surface markers that characterize exosomes and microvesicles, and greater information derived from -omics approaches on the proteins, lipids, mRNAs, and microRNAs (miRNAs) transported by EVs. We have recently discovered a role for exosome-derived miRNAs in age-related bone loss and osteoarthritis, two conditions that impose a significant public health burden on the aging global population...
October 10, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/28955433/trauma-care-in-malawi-a-call-to-action
#20
Wakisa Mulwafu, Linda Chokotho, Nyengo Mkandawire, Hemant Pandit, Dan L Deckelbaum, Chris Lavy, Kathryn H Jacobsen
Injuries are a global public health concern because most are preventable yet they continue to be a major cause of death and disability, especially among children, adolescents, and young adults. This enormous loss of human potential has numerous negative social and economic consequences. Malawi has no formal system of prehospital trauma care, and there is limited access to hospital-based trauma care, orthopaedic surgery, and rehabilitation. While some hospitals and research teams have established local trauma registries and quantified the burden of injuries in parts of Malawi, there is no national injury surveillance database compiling the data needed in order to develop and implement evidence-based prevention initiatives and guidelines to improve the quality of clinical care...
June 2017: Malawi Medical Journal: the Journal of Medical Association of Malawi
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