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Global burden of injury

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https://www.readbyqxmd.com/read/29770123/what-if-low-back-pain-is-the-most-prevalent-parkinsonism-in-the-world
#1
Jesse V Jacobs, Sharon M Henry, Fay B Horak
Low back pain (LBP) has a point prevalence of nearly 10% and ranks highest in global disease burden for years lived with disability; Parkinson's disease (PD) ranks in the top 100 most disabling health conditions for years lost and years lived with disability (1). Recent evidence suggests that people with chronic, recurrent LBP exhibit many postural impairments reminiscent of a neurological postural disorder such as PD. We compare and contrast postural impairments associated with LBP and PD in order to inform treatment strategies for both conditions...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29764476/traumatic-brain-injury-in-uganda-exploring-the-use-of-a-hospital-based-registry-for-measuring-burden-and-outcomes
#2
Amber Mehmood, Nukhba Zia, Connie Hoe, Olive Kobusingye, Hussein Ssenyojo, Adnan A Hyder
OBJECTIVE: Lack of data on traumatic brain injuries (TBI) hinders the appreciation of the true magnitude of the TBI burden. This paper describes a scientific approach for hospital based systematic data collection in a low-income country. The registry is based on the evaluation framework for injury surveillance systems which comprises a four-step approach: (1) identifying characteristics that assess a surveillance system, (2) review of the identified variables based on adopted specific, measurable, assignable, realistic, and time-related criteria, (3) assessment of the proposed variables and system characteristics by an expert panel, and (4) development and application of a rating system...
May 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29760854/peritoneal-dialysis-in-austere-environments-an-emergent-approach-to-renal-failure-management
#3
REVIEW
Chad Gorbatkin, John Bass, Fredric O Finkelstein, Steven M Gorbatkin
Peritoneal dialysis (PD) is a means of renal replacement therapy (RRT) that can be performed in remote settings with limited resources, including regions that lack electrical power. PD is a mainstay of end-stage renal disease (ESRD) therapy worldwide, and the ease of initiation and maintenance has enabled it to flourish in both resource-limited and resource-abundant settings. In natural disaster scenarios, military conflicts, and other austere areas, PD may be the only available life-saving measure for acute kidney injury (AKI) or ESRD...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29732397/causes-of-death-among-children-aged-5-14-years-in-the-who-european-region-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#4
Hmwe H Kyu, Claudia E Stein, Cynthia Boschi Pinto, Ivo Rakovac, Martin W Weber, Tina Dannemann Purnat, Joseph E Amuah, Scott D Glenn, Kelly Cercy, Stan Biryukov, Audra L Gold, Adrienne Chew, Meghan D Mooney, Kevin F O'Rourke, Amber Sligar, Christopher J L Murray, Ali H Mokdad, Mohsen Naghavi
Background: The mortality burden in children aged 5-14 years in the WHO European Region has not been comprehensively studied. We assessed the distribution and trends of the main causes of death among children aged 5-9 years and 10-14 years from 1990 to 2016, for 51 countries in the WHO European Region. Methods: We used data from vital registration systems, cancer registries, and police records from 1980 to 2016 to estimate cause-specific mortality using the Cause of Death Ensemble model...
May 2018: Lancet Child & Adolescent Health
https://www.readbyqxmd.com/read/29730657/adolescent-undernutrition-global-burden-physiology-and-nutritional-risks
#5
Parul Christian, Emily R Smith
Adolescents, comprised of 10-19 year olds, form the largest generation of young people in our history. There are an estimated 1.8 billion adolescents in the world, with 90% residing in low- and middle-income countries. The burden of disease among adolescents has its origins in infectious and injury-related causes, but nutritional deficiencies, suboptimal linear growth, and undernutrition are major public health problems, even as overweight may be on the rise in many contexts. Summary and Key Messages: Girls are most vulnerable to the influences of cultural and gender norms, which often discriminate against them...
May 4, 2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29718971/personal-social-and-environmental-factors-associated-with-lifejacket-wear-in-adults-and-children-a-systematic-literature-review
#6
Amy E Peden, Daniel Demant, Martin S Hagger, Kyra Hamilton
OBJECTIVE: Drowning claims 7% of the global burden of injury-related deaths. Lifejackets are routinely recommended as a drowning prevention strategy; however, a review of related factors regarding lifejacket wear has not previously been investigated. METHODS: This systematic review examined literature published from inception to December 2016 in English and German languages. The personal, social, and environmental factors associated with lifejacket wear among adults and children were investigated, a quantitative evaluation of the results undertaken, and gaps in the literature identified...
2018: PloS One
https://www.readbyqxmd.com/read/29704549/the-role-of-autophagy-in-acute-brain-injury-a-state-of-flux
#7
REVIEW
Michael S Wolf, Hülya Bayır, Patrick M Kochanek, Robert S B Clark
It is established that increased autophagy is readily detectable after various types of acute brain injury, including trauma, focal and global cerebral ischemia. What remains controversial, however, is whether this heightened detection of autophagy in brain represents a homeostatic or pathologic process, or an epiphenomenon. The ultimate role of autophagy after acute brain injury likely depends upon: (Galluzzi et al., 2016) the degree of brain injury and the overall autophagic burden; (Smith et al., 2011) the capacity of individual cell types to ramp up autophagic flux; (Mizushima et al...
April 25, 2018: Neurobiology of Disease
https://www.readbyqxmd.com/read/29701556/estimating-the-global-incidence-of-traumatic-brain-injury
#8
Michael C Dewan, Abbas Rattani, Saksham Gupta, Ronnie E Baticulon, Ya-Ching Hung, Maria Punchak, Amit Agrawal, Amos O Adeleye, Mark G Shrime, Andrés M Rubiano, Jeffrey V Rosenfeld, Kee B Park
OBJECTIVE Traumatic brain injury (TBI)-the "silent epidemic"-contributes to worldwide death and disability more than any other traumatic insult. Yet, TBI incidence and distribution across regions and socioeconomic divides remain unknown. In an effort to promote advocacy, understanding, and targeted intervention, the authors sought to quantify the case burden of TBI across World Health Organization (WHO) regions and World Bank (WB) income groups. METHODS Open-source epidemiological data on road traffic injuries (RTIs) were used to model the incidence of TBI using literature-derived ratios...
April 27, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29701548/global-neurosurgery-the-current-capacity-and-deficit-in-the-provision-of-essential-neurosurgical-care-executive-summary-of-the-global-neurosurgery-initiative-at-the-program-in-global-surgery-and-social-change
#9
Michael C Dewan, Abbas Rattani, Graham Fieggen, Miguel A Arraez, Franco Servadei, Frederick A Boop, Walter D Johnson, Benjamin C Warf, Kee B Park
OBJECTIVE Worldwide disparities in the provision of surgical care result in otherwise preventable disability and death. There is a growing need to quantify the global burden of neurosurgical disease specifically, and the workforce necessary to meet this demand. METHODS Results from a multinational collaborative effort to describe the global neurosurgical burden were aggregated and summarized. First, country registries, third-party modeled data, and meta-analyzed published data were combined to generate incidence and volume figures for 10 common neurosurgical conditions...
April 27, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29691595/-environment-and-the-health-in-all-policies-approach-an-overview
#10
REVIEW
Hajo Zeeb, Henk Hilderink, Sarah Forberger
BACKGROUND: One quarter of the global disease burden could be avoided with management strategies for environmental risk factors such as air and water pollution, food contamination, injuries and poor road safety. Many decisions influencing health are made outside the health sector; thus, the joint consideration and implementation of health and environmental factors in the relevant policies are becoming increasingly important. MATERIALS AND METHODS: By means of a selective literature search, we identified important policy documents and selected research articles as a basis for the introduction and current discussion of the Health in All Policies (HiAP) approach...
April 24, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29682509/initiation-and-propagation-of-vascular-calcification-is-regulated-by-a-concert-of-platelet-and-smooth-muscle-cell-derived-extracellular-vesicles
#11
Leon J Schurgers, Asim C Akbulut, Dawid M Kaczor, Maurice Halder, Rory R Koenen, Rafael Kramann
The ageing population continues to suffer from its primary killer, cardiovascular disease (CVD). Despite recent advances in interventional medicinal and surgical therapies towards the end of the 20th century, the epidemic of cardiovascular disease has not been halted. Yet, rather than receding globally, the burden of CVD has risen to become a top cause of morbidity and mortality worldwide. Most CVD arises from thrombotic rupture of an atherosclerotic plaque, the pathologic thickening of coronary and carotid artery segments and subsequent distal ischemia in heart or brain...
2018: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29659841/incidence-and-mortality-from-adverse-effects-of-medical-treatment-in-the-uk-1990-2013-levels-trends-patterns-and-comparisons
#12
Raimundas Lunevicius, Juanita A Haagsma
Objective: To present an update on incidence and mortality from adverse effects (AEs) of medical treatment in the UK, its four countries and nine English regions between 1990 and 2013. Design: Descriptive epidemiological study on AEs of medical treatment. AEs are shown as a single cause-of-injury category from the Global Burden of Disease (GBD) 2013 study. Data sources: The GBD 2013 interactive data visualisation tools 'Epi Visualisation' and 'GBD Compare'...
April 12, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29593060/the-british-society-of-gastroenterology-uk-pbc-primary-biliary-cholangitis-treatment-and-management-guidelines
#13
Gideon M Hirschfield, Jessica K Dyson, Graeme J M Alexander, Michael H Chapman, Jane Collier, Stefan Hübscher, Imran Patanwala, Stephen P Pereira, Collette Thain, Douglas Thorburn, Dina Tiniakos, Martine Walmsley, George Webster, David E J Jones
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an end-stage biliary cirrhosis. Both genetic and environmental influences are presumed relevant to disease initiation. PBC is most prevalent in women and those over the age of 50, but a spectrum of disease is recognised in adult patients globally; male sex, younger age at onset (<45) and advanced disease at presentation are baseline predictors of poorer outcome...
March 28, 2018: Gut
https://www.readbyqxmd.com/read/29584763/child-injuries-in-ethiopia-a-review-of-the-current-situation-with-projections
#14
Qingfeng Li, Olakunle Alonge, Collene Lawhorn, Yirga Ambaw, Smita Kumar, Troy Jacobs, Adnan A Hyder
BACKGROUND: Heavy burden of child injuries and lack of policy response in Ethiopia call for an improved understanding of the situation and development of action plans from multiple governmental agencies and stakeholders. METHODS: A consortium of international and Ethiopian researchers and stakeholders used extensive literature review and mixed analytical methods to estimate and project the burden of fatal and non-fatal child unintentional injuries in Ethiopia from 2015 to 2030...
2018: PloS One
https://www.readbyqxmd.com/read/29578812/palestinian-nurses-and-doctors-perceptions-and-practices-regarding-the-prevention-of-injuries-to-children-in-the-home-an-explorative-qualitative-study
#15
Intima Alrimawi, Carol Hall, Michael Craig Watson
Unintentional injuries are a growing global public health problem that causes mortality, morbidity, and disability among children. These injuries are common among under-fives and form a significant burden on healthcare systems, particularly in low- and middle-income countries. Nurses and doctors have a major role to play in the prevention of home injuries, as expressed in many international reports. In Palestine, there is a paucity of research in this area. Therefore, this study aims to explore nurses' and doctors' perceptions and practices regarding the prevention of home injuries among children aged under-five years...
March 26, 2018: Comprehensive Child and Adolescent Nursing
https://www.readbyqxmd.com/read/29554115/longitudinal-microstructural-changes-of-cerebral-white-matter-and-their-association-with-mobility-performance-in-older-persons
#16
Nicola Moscufo, Dorothy B Wakefield, Dominik S Meier, Michele Cavallari, Charles R G Guttmann, William B White, Leslie Wolfson
Mobility impairment in older persons is associated with brain white matter hyperintensities (WMH), a common finding in magnetic resonance images and one established imaging biomarker of small vessel disease. The contribution of possible microstructural abnormalities within normal-appearing white matter (NAWM) to mobility, however, remains unclear. We used diffusion tensor imaging (DTI) measures, i.e. fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), radial diffusivity (RD), to assess microstructural changes within supratentorial NAWM and WMH sub-compartments, and to investigate their association with changes in mobility performance, i...
2018: PloS One
https://www.readbyqxmd.com/read/29538456/a-trauma-network-with-centralized-and-local-health-care-structures-evaluating-the-effectiveness-of-the-first-certified-trauma-network-of-the-german-society-of-trauma-surgery
#17
Antonio Ernstberger, Michael Koller, Florian Zeman, Maximilian Kerschbaum, Franz Hilber, Eva Diepold, Julika Loss, Tanja Herbst, Michael Nerlich
BACKGROUND: Trauma is a global burden of disease and one of the main causes of death worldwide. Therefore, many countries around the world have implemented a wide range of different initiatives to minimize mortality rates after trauma. One of these initiatives is the bundling of treatment expertise in trauma centers and the establishment of trauma networks. Germany has a decentralized system of trauma care medical centers. Severely injured patients ought to receive adequate treatment in both level I and level II centers...
2018: PloS One
https://www.readbyqxmd.com/read/29534077/hiv-testing-in-a-south-african-emergency-department-a-missed-opportunity
#18
Bhakti Hansoti, David Stead, Andy Parrish, Steven J Reynolds, Andrew D Redd, Madeleine M Whalen, Nomzamo Mvandaba, Thomas C Quinn
BACKGROUND: South Africa has the largest HIV epidemic in the world, with 19% of the global number of people living with HIV, 15% of new infections and 11% of AIDS-related deaths. Even though HIV testing is mandated in all hospital-based facilities in South Africa (SA), it is rarely implemented in the Emergency Department (ED). The ED provides episodic care to large volumes of undifferentiated who present with unplanned injury or illness. Thus, the ED may provide an opportunity to capture patients with undiagnosed HIV infection missed by clinic-based screening programs...
2018: PloS One
https://www.readbyqxmd.com/read/29530315/epigenetic-modulation-of-macrophage-polarization-perspectives-in-diabetic-wounds
#19
REVIEW
Sanchari Basu Mallik, B S Jayashree, Rekha R Shenoy
Diabetes is a chronic metabolic disorder that poses a global burden to healthcare. Increasing incidence of diabetes-related complications in the affected population includes a delay in wound healing that often results in non-traumatic limb amputations. Owing to the intricacies of the healing process and crosstalk between the multitude of participating cells, the identification of hyperglycaemia-induced changes at both cellular and molecular levels poses a challenge. Macrophages are one of the key participants in wound healing and continue to exert functional changes at the wound site since the time of injury...
February 7, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29490646/a-bibliometric-analysis-of-the-published-road-traffic-injuries-research-in-india-post-1990
#20
REVIEW
Neeraj Sharma, Mohan Bairwa, B Gowthamghosh, S D Gupta, D K Mangal
BACKGROUND: Globally, road traffic injuries are the leading cause of death among those aged 15-29 years. However, road traffic injury research has not received adequate attention from the scientific community in low- and middle-income countries, including India. The present study aims to provide a bibliometric overview of research assessing road traffic injuries in India. METHODS: We used Scopus to extract relevant research in road traffic injuries published from 1991 to 2017...
March 1, 2018: Health Research Policy and Systems
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