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Global burden of injury

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https://www.readbyqxmd.com/read/28818961/an-analogy-between-socioeconomic-deprivation-level-and-loss-of-health-from-adverse-effects-of-medical-treatment-in-england
#1
Raimundas Lunevicius, Juanita A Haagsma
BACKGROUND: The purpose of this study was to show whether and how levels, trends and patterns obtained from estimates of premature deaths from adverse effects (AEs) of medical treatment depended on the deprivation level in England over the 24-year period, 1990-2013. We provide a report to inform decision-making strategies to reduce the burden of disease arising from AEs of medical treatment in the most deprived areas of the country. METHODS: Comparative analysis was driven by a single cause-of-injury category-AEs of medical treatment-from the Global Burden of Disease 2013 study...
August 17, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28803723/perceived-social-support-among-patients-with-burn-injuries-a-perspective-from-the-developing-world
#2
Ahmed Waqas, Marvee Turk, Sadiq Naveed, Atif Amin, Harriet Kiwanuka, Neha Shafique, Muhammad Ashraf Chaudhry
BACKGROUND: Social support is among the most well-established predictors of post-burn psychopathology after burn. Despite a disproportionately large burden of burns in the developing world, the nature of social support among burn patients in this context remains elusive. We, therefore, seek to investigate social support and its biopsychosocial determinants among patients with burn injuries in Pakistan. METHODS: A cross-sectional study of 343 patients presenting with burn injuries at four teaching hospitals in the Punjab province of Pakistan was conducted...
August 10, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28799580/risk-prediction-of-acute-kidney-injury-by-timp-2-%C3%A2-igfbp7
#3
M Kimmel, M Schanz, M D Alscher
Acute kidney injury (AKI) is a common syndrome with increased mortality, a heavy burden of illness and high cost. The Kidney Disease Improving Global Outcomes (KDIGO) criteria for staging of AKI have been validated in large patient cohorts and classify AKI into three stages. In order to achieve prevention or early therapy, the focus of scientific interest is early detection and risk prediction of AKI. The combination of the two cell cycle arrest markers [TIMP-2]·[IGFBP7] in the urine shows good results in the risk prediction of AKI in different clinical settings (intensive care medicine, sepsis, cardiac surgery, emergency department)...
June 2017: Drugs of Today
https://www.readbyqxmd.com/read/28796160/epidemiology-of-fall-injury-in-rural-bangladesh
#4
Shirin Wadhwaniya, Olakunle Alonge, Md Kamran Ul Baset, Salim Chowdhury, Al-Amin Bhuiyan, Adnan A Hyder
Globally, falls are the second leading cause of unintentional injury deaths, with 80% occurring in low-and middle-income countries. The overall objective of this study is to describe the burden and risk factors of falls in rural Bangladesh. In 2013, a large household survey covering a population of 1,169,593 was conducted in seven rural sub-districts of Bangladesh to assess the burden of all injuries, including falls. The recall periods for non-fatal and fatal injuries were six and 12 months, respectively. Descriptive, bivariate and multiple logistic regression analyses were conducted...
August 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28792274/global-regional-and-national-prevalence-incidence-and-disability-adjusted-life-years-for-oral-conditions-for-195-countries-1990-2015-a-systematic-analysis-for-the-global-burden-of-diseases-injuries-and-risk-factors
#5
N J Kassebaum, A G C Smith, E Bernabé, T D Fleming, A E Reynolds, T Vos, C J L Murray, W Marcenes
The Global Burden of Disease 2015 study aims to use all available data of sufficient quality to generate reliable and valid prevalence, incidence, and disability-adjusted life year (DALY) estimates of oral conditions for the period of 1990 to 2015. Since death as a direct result of oral diseases is rare, DALY estimates were based on years lived with disability, which are estimated only on those persons with unmet need for dental care. We used our data to assess progress toward the Federation Dental International, World Health Organization, and International Association for Dental Research's oral health goals of reducing the level of oral diseases and minimizing their impact by 2020...
April 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28780000/systemic-infusions-of-anti-interleukin-1%C3%AE-neutralizing-antibodies-reduce-short-term-brain-injury-after-cerebral-ischemia-in-the-ovine-fetus
#6
Xiaodi Chen, Virginia Hovanesian, Syed Naqvi, Yow-Pin Lim, Richard Tucker, John E Donahue, Edward G Stopa, Barbara S Stonestreet
Perinatal hypoxic-ischemic reperfusion (I/R)-related brain injury is a leading cause of neurologic morbidity and life-long disability in children. Infants exposed to I/R brain injury develop long-term cognitive and behavioral deficits, placing a large burden on parents and society. Therapeutic strategies are currently not available for infants with I/R brain damage, except for hypothermia, which can only be used in full term infants with hypoxic-ischemic encephalopathy (HIE). Moreover, hypothermia is only partially protective...
August 2, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28776255/transport-injuries-and-deaths-in-the-eastern-mediterranean-region-findings-from-the-global-burden-of-disease-2015-study
#7
Ali H Mokdad
OBJECTIVES: Transport injuries (TI) are ranked as one of the leading causes of death, disability, and property loss worldwide. This paper provides an overview of the burden of TI in the Eastern Mediterranean Region (EMR) by age and sex from 1990 to 2015. METHODS: Transport injuries mortality in the EMR was estimated using the Global Burden of Disease mortality database, with corrections for ill-defined causes of death, using the cause of death ensemble modeling tool...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28776253/adolescent-health-in-the-eastern-mediterranean-region-findings-from-the-global-burden-of-disease-2015-study
#8
Ali H Mokdad
OBJECTIVES: The 22 countries of the East Mediterranean Region (EMR) have large populations of adolescents aged 10-24 years. These adolescents are central to assuring the health, development, and peace of this region. We described their health needs. METHODS: Using data from the Global Burden of Disease Study 2015 (GBD 2015), we report the leading causes of mortality and morbidity for adolescents in the EMR from 1990 to 2015. We also report the prevalence of key health risk behaviors and determinants...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28776251/intentional-injuries-in-the-eastern-mediterranean-region-1990-2015-findings-from-the-global-burden-of-disease-2015-study
#9
Ali H Mokdad
OBJECTIVES: We used GBD 2015 findings to measure the burden of intentional injuries in the Eastern Mediterranean Region (EMR) between 1990 and 2015. METHODS: The Global Burden of Disease (GBD) study defines intentional injuries as a combination of self-harm (including suicide), interpersonal violence, collective violence (war), and legal intervention. We estimated number of deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) for each type of intentional injuries...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28776247/the-burden-of-mental-disorders-in-the-eastern-mediterranean-region-1990-2015-findings-from-the-global-burden-of-disease-2015-study
#10
Ali H Mokdad
OBJECTIVES: Mental disorders are among the leading causes of nonfatal burden of disease globally. METHODS: We used the global burden of diseases, injuries, and risk factors study 2015 to examine the burden of mental disorders in the Eastern Mediterranean region (EMR). We defined mental disorders according to criteria proposed in the diagnostic and statistical manual of mental disorders IV and the 10th International Classification of Diseases. RESULTS: Mental disorders contributed to 4...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28776238/danger-ahead-the-burden-of-diseases-injuries-and-risk-factors-in-the-eastern-mediterranean-region-1990-2015
#11
Ali H Mokdad
OBJECTIVES: The Eastern Mediterranean Region faces several health challenges at a difficult time with wars, unrest, and economic change. METHODS: We used the Global Burden of Disease 2015 study to present the burden of diseases, injuries, and risk factors in the Eastern Mediterranean Region from 1990 to 2015. RESULTS: Ischemic heart disease was the leading cause of death in the region in 2015, followed by cerebrovascular disease. Changes in total deaths ranged from a reduction of 25% for diarrheal diseases to an increase of about 42% for diabetes and tracheal, bronchus, and lung cancer...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28761509/newer-insights-to-pathogenesis-of-traumatic-brain-injury
#12
REVIEW
Sunil Munakomi, Iype Cherian
Traumatic brain injury (TBI) is a silent epidemic and a global burden. However, when it comes to advancement in our quest to managing patients with head injuries, we seem to be making circles rather than moving forward. In this review paper, we focus on the current understandings in the pathogenesis of TBI that may aid us in providing newer avenues in management of the same.
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28757551/evaluating-the-effectiveness-of-implementing-a-more-severe-drunk-driving-law-in-china-findings-from-two-open-access-data-sources
#13
Wangxin Xiao, Peishan Ning, David C Schwebel, Guoqing Hu
In 2011, China implemented a more severe drunk-driving law. This study evaluated the effectiveness of the law on road traffic morbidity and mortality attributed to alcohol use. Data were from two open-access data sources, the Global Burden of Disease (GBD) 2015 update and police data. Poisson regression examined the significance of changes in morbidity and mortality. Large gaps in crude death estimates from road traffic crashes attributed to alcohol use emerged between the two data sources. For the GBD 2015 update, crude and age-standardized mortality displayed consistent trends between 1990 and 2015; age-standardized mortality per 100,000 persons increased from 5...
July 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28757259/endotoxemia-induces-lung-brain-coupling-and-multi-organ-injury-following-cerebral-ischemia-reperfusion
#14
Nguyen Mai, Landa Prifti, Aric Rininger, Hannah Bazarian, Marc W Halterman
Post-ischemic neurodegeneration remains the principal cause of mortality following cardiac resuscitation. Recent studies have implicated gastrointestinal ischemia in the sepsis-like response associated with the post-cardiac arrest syndrome (PCAS). However, the extent to which the resulting low-grade endotoxemia present in up to 86% of resuscitated patients affects cerebral ischemia-reperfusion injury has not been investigated. Here we report that a single injection of low-dose lipopolysaccharide (50μg/kg, IP) delivered after global cerebral ischemia (GCI) induces blood-brain barrier permeability, microglial activation, cortical injury, and functional decline in vivo, compared to ischemia alone...
July 28, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28746656/mortality-due-to-noncommunicable-diseases-in-brazil-1990-to-2015-according-to-estimates-from-the-global-burden-of-disease-study
#15
Deborah Carvalho Malta, Elisabeth França, Daisy Maria Xavier Abreu, Rosângela Durso Perillo, Maíra Coube Salmen, Renato Azeredo Teixeira, Valeria Passos, Maria de Fátima Marinho Souza, Meghan Mooney, Mohsen Naghavi
CONTEXT AND OBJECTIVE: Noncommunicable diseases (NCDs) are the leading health problem globally and generate high numbers of premature deaths and loss of quality of life. The aim here was to describe the major groups of causes of death due to NCDs and the ranking of the leading causes of premature death between 1990 and 2015, according to the Global Burden of Disease (GBD) 2015 study estimates for Brazil. DESIGN AND SETTING: Cross-sectional study covering Brazil and its 27 federal states...
May 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28745903/trend-of-socio-demographic-index-and-mortality-estimates-in-iran-and-its-neighbors-1990-2015-findings-of-the-global-burden-of-diseases-2015-study
#16
Maziar Moradi-Lakeh, Sadaf G Sepanlou, Seyed M Karimi, Narjes Khalili, Shirin Djalalinia, Chante Karimkhani, Kristopher Krohn, Ashkan Afshin, Farshad Farzadfar, Aliasghar Ahmad Kiadaliri, Mohsen Asadi-Lari, Hamid Asayesh, Ali Reza Esteghamati, Maryam S Farvid, Seyed-Mohammad Fereshtehnejad, Pouria Heydarpour, Ardeshir Khosravi, Jagdish Khubchandani, Amir Kasaeian, Saleem M Rana, Mahdi Mahdavi, Habib Masoudifarid, Alireza Mohammadi, Farshad Pourmalek, Mostafa Qorbani, Amir Radfar, Kazem Rahimi, Vafa Rahimi-Movaghar, Gholamreza Roshandel, Sare Safi, Payman Salamati, Arash Tehrani-Banihashemi, Shahrzad Bazargan-Hejazi, Theo Vos, Reza Malekzadeh, Ali H Mokdad, Christopher J L Murray, Mohsen Naghavi
BACKGROUND: The Global burden of disease and injuries study (GBD 2015) reports expected measures for years of life lost (YLL) based on socio-demographic index (SDI) of countries, as well as the observed measures. In this extended GBD 2015 report, we reviewed total and cause-specific deaths and YLL for Iran and all its neighboring countries between 1990 and 2015. METHODS: We extracted data from the GBD 2015 database. Observed YLL measures were calculated by multiplying the number of deaths by standard life expectancy at each age...
July 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28745902/disability-adjusted-life-years-dalys-for-315-diseases-and-injuries-and-healthy-life-expectancy-hale-in-iran-and-its-neighboring-countries-1990-2015-findings-from-global-burden-of-disease-study-2015
#17
Sadaf G Sepanlou, Mahboubeh Parsaeian, Kristopher J Krohn, Ashkan Afshin, Farshad Farzadfar, Gholamreza Roshandel, Chante Karimkhani, Sharzad Bazargan-Hejazi, Aliasghar Ahmad Kiadaliri, Hamid Ahmadieh, Shirin Djalalinia, Hedyeh Ebrahimi, Babak Eshrati, Ali Reza Esteghamati, Maryam S Farvid, Seyed-Mohammad Fereshtehnejad, Nima Hafezi-Nejad, Mohammad Sadegh Hassanvand, Pouria Heydarpour, Farhad Islami, Seyed M Karimi, Marzieh Katibeh, Ardeshir Khosravi, Jagdish Khubchandani, Mahdi Mahdavi, Farhad Pishgar, Mostafa Qorbani, Vafa Rahimi-Movaghar, Sare Safi, Mohammad Ali Sahraian, Saeid Shahraz, Sara Sheikhbahaei, Alireza Mohammadi, Ali H Mokdad, Theo Vos, Christopher J L Murray, Maziar Moradi-Lakeh, Mohsen Naghavi, Reza Malekzadeh
BACKGROUND: Summary measures of health are essential in making estimates of health status that are comparable across time and place. They can be used for assessing the performance of health systems, informing effective policy making, and monitoring the progress of nations toward achievement of sustainable development goals. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) provides disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) as main summary measures of health...
July 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28745901/prevalence-and-years-lived-with-disability-of-310-diseases-and-injuries-in-iran-and-its-neighboring-countries-1990-2015-findings-from-global-burden-of-disease-study-2015
#18
Shirin Djalalinia, Sahar Saeedi Moghaddam, Maziar Moradi-Lakeh, Saeid Shahraz, Mohsen Naghavi, Christopher J L Murray, Theo Vos, Ali H Mokhdad, Kris Krohn, Goodarz Danaei, Ashkan Afshin, Sadaf G Sepanlou, Shahrzad Bazargan-Hejazi, Niloofar Peykari, Nazila Rezaei, Gholamreza Roshandel, Chante Karimkhani, Babak Moazen, Farshad Pourmalek, Ali Reza Esteghamati, Nima Hafezi-Nejad, Sara Sheikhbahaei, Marzieh Katibeh, Hamid Ahmadieh, Sare Safi, Mostafa Qorbani, Farhad Islami, Ardeshir Khosravi, Mohammad Sadegh Hasanvand, Mahdi Mahdavi, Aliasghar A Kiadaliri, Maryam S Farvid, Seyed M Karimi, Alireza Mohammadi, Hamid Asayesh, Reza Assadi, Jagdish Khubchandani, Pouria Heydarpour, Seyed Mohammad Fereshtehnejad, Saeid Safiri, Amir Kasaeian, Bagher Larijani, Reza Malekzadeh, Farshad Farzadfar
BACKGROUND: Due to significant achievements in reducing mortality and increasing life expectancy, the issue of disability from diseases and injuries, and their related interventions, has become one of the most important concerns of health-related research. METHODS: Using data obtained from the GBD 2015 study, the present report provides prevalence and years lived with disability (YLDs) of 310 diseases and injuries by sex and age in Iran and neighboring countries over the period 1990-2015...
July 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28736507/national-mortality-burden-due-to-communicable-non-communicable-and-other-diseases-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#19
Awoke Misganaw, Tilahun N Haregu, Kebede Deribe, Gizachew Assefa Tessema, Amare Deribew, Yohannes Adama Melaku, Azmeraw T Amare, Semaw Ferede Abera, Molla Gedefaw, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Kristopher J Krohn, Tom Achoki, Jed Blore, Yibeltal Assefa, Mohsen Naghavi
BACKGROUND: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) estimates to describe the mortality burden from communicable, non-communicable, and other diseases in Ethiopia over the last 25 years. METHODS: GBD 2015 mainly used cause of death ensemble modeling to measure causes of death by age, sex, and year for 195 countries...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28736506/national-disability-adjusted-life-years-dalys-for-257-diseases-and-injuries-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#20
Awoke Misganaw, Yohannes Adama Melaku, Gizachew Assefa Tessema, Amare Deribew, Kebede Deribe, Semaw Ferede Abera, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Tilahun N Haregu, Azmeraw T Amare, Molla Gedefaw, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Tom Achoki, Jed Blore, Kristopher J Krohn, Yibeltal Assefa, Mahlet Kifle, Mohsen Naghavi
BACKGROUND: Disability-adjusted life years (DALYs) provide a summary measure of health and can be a critical input to guide health systems, investments, and priority-setting in Ethiopia. We aimed to determine the leading causes of premature mortality and disability using DALYs and describe the relative burden of disease and injuries in Ethiopia. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for non-fatal disease burden, cause-specific mortality, and all-cause mortality to derive age-standardized DALYs by sex for Ethiopia for each year...
2017: Population Health Metrics
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