Sangeetha Senthil Kumar, Venugopal Gunda, Dakota M Reinartz, Kelvin W Pond, Curtis A Thorne, Paul Victor Santiago Raj, Michael D L Johnson, Justin E Wilson
Oral streptococci, key players in oral biofilm formation, are implicated in oral dysbiosis and various clinical conditions, including dental caries, gingivitis, periodontal disease, and oral cancer. Specifically, Streptococcus anginosus is associated with esophageal, gastric, and pharyngeal cancers, while Streptococcus mitis is linked to oral cancer. However, no study has investigated the mechanistic links between these Streptococcus species and cancer-related inflammatory responses. As an initial step, we probed the innate immune response triggered by S...
January 30, 2024: Infection and Immunity