keyword
https://read.qxmd.com/read/38306531/empyema-caused-by-actinomyces-odontolyticus-a-case-report
#21
JOURNAL ARTICLE
Min Wang, Qianfeng Xiao, Kaige Wang
RATIONALE: Actinomyces odontolyticus causes a rare, chronic granulomatous infection that is frequently associated with immunocompromised states. A odontolyticus can cause infection in multiple organs, but empyema is rare. PATIENT CONCERNS: We report a case of empyema caused by A odontolyticus. The patient was a 64-year-old man. He was admitted to the hospital with a 5-day history of fever and dyspnea. He had caries and sequelae of cerebral apoplexy. DIAGNOSES: Metagenome next generation sequencing of pleural effusion was positive for A odontolyticus...
February 2, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38305472/bioengineered-ionic-liquid-for-catheter-directed-tissue-ablation-drug-delivery-and-embolization
#22
JOURNAL ARTICLE
Hyeongseop Keum, Hassan Albadawi, Zefu Zhang, Erin Graf, Pedro Reck Dos Santos, Seyda Gunduz, Rahmi Oklu
Delivery of therapeutics to solid tumors with high bioavailability remains a challenge and is likely the main contributor to the ineffectiveness of immunotherapy and chemotherapy. Here, a catheter-directed ionic liquid embolic (ILE) was bioengineered to achieve durable vascular embolization, uniform tissue ablation, and drug delivery in non-survival and survival porcine models of embolization, outperforming the clinically used embolic agents. To simulate the clinical scenario, rabbit VX2 orthotopic liver tumors were treated showing successful trans-arterial delivery of Nivolumab and effective tumor ablation...
February 2, 2024: Advanced Materials
https://read.qxmd.com/read/38295417/case-report-pericardial-actinomycosis-in-a-79-year-old-man-with-poor-dental-hygiene
#23
Chun-Hsun Liao, Tzong-Yow Wu, Yen-Liang Lin, Wang-Da Liu, Jann-Tay Wang, Jin-Shing Chen, Yi-Lwun Ho
Actinomycosis is an uncommon infection caused by Actinomyces species, and the diagnosis is often challenging owing to low prevalence and diverse clinical manifestations. Pericardial involvement of actinomycosis is particularly rare. Here, we present a case of a 79-year-old man who initially complained of exertional dyspnea, orthopnea, and decreased urine amount. There was no fever, chest pain, or productive cough. Physical examination was remarkable for decreased breath sounds at the left lower lung field. Poor dental hygiene and a firm, well-defined mass without discharge over the hard palate were noted...
January 30, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38289109/oral-streptococci-s-anginosus-and-s-mitis-induce-distinct-morphological-inflammatory-and-metabolic-signatures-in-macrophages
#24
JOURNAL ARTICLE
Sangeetha Senthil Kumar, Venugopal Gunda, Dakota M Reinartz, Kelvin W Pond, Curtis A Thorne, Paul Victor Santiago Raj, Michael D L Johnson, Justin E Wilson
Oral streptococci, key players in oral biofilm formation, are implicated in oral dysbiosis and various clinical conditions, including dental caries, gingivitis, periodontal disease, and oral cancer. Specifically, Streptococcus anginosus is associated with esophageal, gastric, and pharyngeal cancers, while Streptococcus mitis is linked to oral cancer. However, no study has investigated the mechanistic links between these Streptococcus species and cancer-related inflammatory responses. As an initial step, we probed the innate immune response triggered by S...
January 30, 2024: Infection and Immunity
https://read.qxmd.com/read/38283534/dental-infection-causing-methicillin-resistant-staphylococcus-aureus-bacteremia-and-spinal-infection-a-case-report
#25
Nicholas R Munoz, Ali Ghorbani, Chibuike C Agwuegbo, John M Vincent Coralde
Poor dentition as a source of infection causing bacteremia and spinal infections (such as paraspinal abscess, and discitis) should be considered even in the absence of recent dental surgery. The case presents a patient found to have an infection in the cervical and thoracic spine, methicillin-resistant Staphylococcus aureus  bacteremia, and poor dentition. Although the patient had a history of drug use, he denied a history of intravenous drug use. He had Crohn's disease that resulted in periodontal and endodontal tooth disease...
December 2023: Curēus
https://read.qxmd.com/read/38276050/silver-diamine-fluoride-renaissance-in-paediatric-dentistry-a-24-month-retrospective-and-cross-sectional-analysis
#26
JOURNAL ARTICLE
Ruba Abdulrahim, Christian H Splieth, Mhd Said Mourad, Annina Vielhauer, Manasi R Khole, Ruth M Santamaría
Background and Objectives: Silver diamine fluoride (SDF) has been incorporated into the treatment of dental caries in children, mainly in countries with high caries prevalence. In Europe, however, SDF started to gain popularity during the COVID-19 pandemic. This study aimed to investigate the efficacy of SDF and to evaluate dentists'/parents' acceptance of SDF use in paediatric patients treated in a German university setting. Materials and Methods: A retrospective analysis of all patients treated with SDF between 2017 and 2020 was carried out...
December 21, 2023: Medicina
https://read.qxmd.com/read/38259367/developmental-disturbance-in-premolars-after-intraligamental-anesthesia-using-computer-controlled-local-anesthesia-delivery-system-an-eight-years-follow-up-study-in-children
#27
JOURNAL ARTICLE
Khlood Baghlaf, Sara M Bagher, Rana A Alamoudi, Ehda Falemban, Hanin Badiab, Heba Sabbagh
Aim This study aimed to evaluate the prevalence of developmental disturbances in permanent second premolars in which their tooth buds were exposed to mandibular intraligamental anesthesia (ILA) using a computer-controlled local anesthetic delivery system (CCLAD). Materials and methods This was a longitudinal follow-up study conducted in a previous randomized clinical trial (RCT). In the previous RCT, a total of 91 children were included (61 control and 30 cases). A structured form was created that contained details about the date of birth, age, and sex at which the participants received local anesthesia and the type of local anesthesia administered (ILA using CCLADS, traditional inferior alveolar nerve block [IANB], and IANB using CCLADS)...
December 2023: Curēus
https://read.qxmd.com/read/38200276/successful-surgical-treatment-of-an-intraoperatively-ruptured-lung-abscess-rupture-using-free-pericardial-fat-implantation-a-case-report
#28
JOURNAL ARTICLE
Yoshihito Iijima, Takaki Mizoguchi, Masahito Ishikawa, Shun Iwai, Nozomu Motono, Hidetaka Uramoto
BACKGROUND: Lung abscess treatment results the treatment results improved with the development of antibiotics; however, surgical treatment is indicated when pyothorax is present, surgical treatment is indicated. When a lung abscess ruptures, pyothorax and fistula occur, which are difficult to treat. CASE PRESENTATION: A 74-year-old woman who experienced exacerbated dyspnea and left back pain for 10 days was diagnosed with a lung abscess caused by an odontogenic infection...
January 11, 2024: Surgical Case Reports
https://read.qxmd.com/read/38189967/reliability-of-large-language-models-in-managing-odontogenic-sinusitis-clinical-scenarios-a-preliminary-multidisciplinary-evaluation
#29
JOURNAL ARTICLE
Alberto Maria Saibene, Fabiana Allevi, Christian Calvo-Henriquez, Antonino Maniaci, Miguel Mayo-Yáñez, Alberto Paderno, Luigi Angelo Vaira, Giovanni Felisati, John R Craig
PURPOSE: This study aimed to evaluate the utility of large language model (LLM) artificial intelligence tools, Chat Generative Pre-Trained Transformer (ChatGPT) versions 3.5 and 4, in managing complex otolaryngological clinical scenarios, specifically for the multidisciplinary management of odontogenic sinusitis (ODS). METHODS: A prospective, structured multidisciplinary specialist evaluation was conducted using five ad hoc designed ODS-related clinical scenarios...
January 8, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38186473/streptococcus-viridans-liver-abscess-and-septicemia-likely-secondary-to-a-swallowed-dental-bridge
#30
Shannon Monro, Eleonora Feketeova
Pyogenic liver abscesses are relatively rare in developed countries such as the United States, and, when they do occur, they are typically secondary to direct or hematogenous spread of intra-abdominal pathologies. Gastrointestinal pathogens such as  Escherichia coli and Enterococcus species are typically implicated. Conversely, the Streptococcus viridans group is a rare cause of bacteremia and abscess formation, especially in immunocompetent patients. We present a case of a 53-year-old male who presented with S...
December 2023: Curēus
https://read.qxmd.com/read/38183165/prevalence-of-acute-periapical-abscesses-in-head-and-neck-cancer-patients-receiving-radiotherapy
#31
JOURNAL ARTICLE
Joseph Katz, Olga S Ensz, Ilan Rotstein
AIMS: Head and neck cancer is a serious condition affecting the life of patients. Radiotherapy is commonly used to treat such conditions. The aim of this study was to assess the prevalence of acute periapical abscesses (PAs) in patients who received radiotherapy for head and neck cancer. METHODS AND RESULTS: Data on acute PAs and oropharyngeal cancer (OPC) diagnosis with or without a history of radiation therapy (RAD) was retrieved by searching the appropriate query in the database...
January 5, 2024: Special Care in Dentistry
https://read.qxmd.com/read/38179366/assessment-of-oral-mucosal-lesions-oml-periodontal-health-conditions-and-unmet-dental-treatment-needs-in-the-rural-adult-population-of-jharkhand-north-india
#32
JOURNAL ARTICLE
Sandeep Kumar, Tapan K Mandal, Arunoday Kumar, Manawar Ahmad, Hina Naim, Jagadesaan N
Background Dental diseases like caries, periodontal diseases, and oral mucosal lesions (OML) are common findings in rural adult populations that greatly impact their quality of life. Aim To assess OML, periodontal health conditions, and unmet dental treatment needs in the rural adult population in Jharkhand. Methodology A total of 700 permanent residents of Bero Block, Jharkhand, North India, in the age group of 35-44 years, participated in this cross-sectional study. Both men and women were equally represented...
December 2023: Curēus
https://read.qxmd.com/read/38178193/oculo-facio-cardio-dental-ofcd-syndrome-a-case-report
#33
JOURNAL ARTICLE
Tung Thanh Nguyen, Anh Thai Hoang Truong, Vu Anh Hoang, Duong Van Huynh, Tuan Van Nguyen, Chanh Trung Le, Dung Thi Phuong Dang, Minh Huu Nhat Le
BACKGROUND: Oculo-facio-cardio-dental (OFCD) syndrome is a rare condition that affects the eyes, face, heart, and teeth of patients. One notable dental characteristic of OFCD is radiculomegaly, or root gigantism, which highlights the role of dentists in detecting this syndrome. OFCD is an X-linked dominant syndrome that results from a variant in the BCOR gene. Our study presents the first documented case of OFCD in Vietnam and reports a novel BCOR gene variant observed in this case. CASE PRESENTATION: A 19-year-old Vietnamese female patient with an extremely long root with an abscess was clinically examined for the expression of OFCDs...
January 4, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38166457/dental-surgical-activity-in-hospitals-during-covid-19-a-nationwide-observational-cohort-study
#34
JOURNAL ARTICLE
J Booth, A J Fowler, R Pearse, P Dias, Y I Wan, R Witton, T E F Abbott
INTRODUCTION: The number of surgical extractions performed in hospitals in England remains unclear. This study reports the volume of surgical extractions conducted in hospitals and change in activity during the COVID-19 pandemic. METHODS: We conducted a nationwide observational cohort study using Hospital Episode Statistics (HES) in England for patients undergoing surgical removal of a tooth (defined using OPSC-4 code F09) between April 1, 2015, and December 31, 2020...
January 3, 2024: JDR Clinical and Translational Research
https://read.qxmd.com/read/38161605/lingual-abscess-after-posterior-fossa-surgery-an-unusual-complication-of-the-concorde-position
#35
Debajyoti Datta, Debarshi Chatterjee, Mona Tiwari
Posterior fossa tumors are one of the most common tumors occurring in children. These tumors are often operated in the Concorde or prone position. Venous congestion can occur due to neck flexion during the positioning causing macroglossia. We report a case of a lingual abscess in a child after surgery in the Concorde position. There was no preoperative evidence of any lingual and dental complaints or injury during intubation. We hypothesize that the lingual abscess in the immediate postoperative period was secondary to venous stasis during the positioning for surgery...
December 2023: Asian Journal of Neurosurgery
https://read.qxmd.com/read/38152944/clinical-and-radiographic-evaluation-of-various-herbal-products-used-with-zinc-oxide-as-an-obturating-material-in-primary-teeth-an-in-vivo-study
#36
JOURNAL ARTICLE
Sunil, Siddharth Anand, Asib Ahmad, Ravi Prakash, Aparna Singh, Vasundhara Megha
AIM: To compare the clinical and radiographically mixture of zinc oxide with Aloe vera , Curcumin and neem as an obturating material for pulpectomy. MATERIALS AND METHODS: The study comprised of age group 4-8 years children requiring endodontic treatment for at least a single primary molar tooth. Sixty primary molar teeth from 43 children were divided equally and randomly into four study groups. The materials used for obturation were zinc oxide powder (ZnO) and Eugenol (ZOE) (group I), ZnO and Aloe vera Gel (group II), ZnO and Curcumin Powder (group III), ZnO and neem extract (group IV)...
September 1, 2023: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/38150667/photothermal-and-photocatalytic-glycol-chitosan-and-polydopamine-grafted-oxygen-vacancy-bismuth-oxyiodide-bio-1-x-i-nanoparticles-for-the-diagnosis-and-targeted-therapy-of-diabetic-wounds
#37
JOURNAL ARTICLE
Jianglong Kong, Sihan Ma, Runxuan Chu, Jiawen Liu, Hongrui Yu, Meiru Mao, Xiaohan Ge, Yuting Sun, Yi Wang
Treatment of diabetic wounds is a significant clinical challenge due to the massive infections caused by bacteria. In this study, multifunctional glycol chitosan and polydopamine-coated BiO1-x I (GPBO) nanoparticles (NPs) with near-infrared (NIR) photothermal and photocatalytic abilities are prepared. When infection occurs, the local microenvironment becomes acidic, and the pH-switchable GPBO can target the bacteria of the wound site. The NIR-assisted GPBO treatment exhibits anti-bacterial effects with fast response, high efficiency, and long duration to Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus...
December 27, 2023: Advanced Materials
https://read.qxmd.com/read/38146388/descending-necrotizing-mediastinitis-caused-by-retro-pharyngeal-eggerthia-catenaformis-infection
#38
Alessandro Graziani, Maria Vittoria Tamburini, Francesco Congestrì, Ludovico Graziani, Maria Giulia Sama, Guido Caroli, Riccardo Spaggiari
INTRODUCTION: Eggerthia catenaformis , a non-spore-forming anaerobic Gram-positive bacillus component of the human fecal microbiota has rarely been reported in human diseases. In almost every case described in current literature to date, dental diseases (abscesses, periodontitis, or caries), are the most common source of the infection which extends to the brain, cervical spaces, pulmonary parenchyma, the pleural cavity, the abdominal wall, and the abdominal cavity. CASE REPORT: An 82-year-old male Caucasian patient was admitted to our Emergency Department (ED) with a painless, right submandibular mass, dyspnea, and inspiratory stridor...
September 2023: Germs
https://read.qxmd.com/read/38137614/x-linked-hypophosphatemia-does-targeted-therapy-modify-dental-impairment
#39
REVIEW
Anusha Abdullah, Sabina Noreen Wuersching, Maximilian Kollmuss, Philipp Poxleitner, Ina Dewenter, Leonard Simon Brandenburg, David Steybe, Florian Nepomuk Fegg, Wenko Smolka, Sven Otto, Katharina Theresa Obermeier
X-linked hypophosphatemia is a rare, hereditary disorder that significant influences teeth and alveolar bone. The first clinical sign leading to the diagnosis of X-linked hypophosphatemia is often dental impairment with dental abscesses and dentin mineralization defects. Genetic analysis helped find the responsible gene and therefore opened up new ways of therapeutically managing X-linked hypophosphatemia. The human monoclonal antibody Burosumab represents a milestone in the targeted therapy of this hereditary disease by directly addressing its pathophysiology...
December 7, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38133469/genetic-polymorphism-of-interleukins-6-and-17-correlated-with-apical-periodontitis-a-cross-sectional-study
#40
JOURNAL ARTICLE
Rebeka Thiara Nascimento Dos Santos, Luísa Priscilla Oliveira de Lima, Maria Tereza Cartaxo Muniz, Pâmella Recco Álvares, Márcia Maria Fonseca da Silveira, Ana Paula Veras Sobral
Interleukins 6 and 17 act in bone resorption in the presence of infections of endodontic origin for host defense. Genetic polymorphisms may be associated with increased bone loss, represented by areas of large periapical lesions. This study aimed to verify the frequency of interleukin 6 and 17 gene polymorphism in patients with asymptomatic apical periodontitis or chronic apical abscess and to verify the existence of correlations between periapical lesion area with age, gender, and presence of the polymorphism, in the studied population, in the state of Pernambuco...
2023: Brazilian Dental Journal
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