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https://www.readbyqxmd.com/read/27772758/role-of-18-f-fdg-pet-in-demonstrating-disease-burden-in-patients-with-tuberculous-meningitis
#1
Sanjay Gambhir, Mritunjai Kumar, Mudalsha Ravina, Sanjeev Kumar Bhoi, Jayantee Kalita, U K Misra
OBJECTIVE: To study the role of (18)fluoro-deoxy glucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scan in documenting the disease burden in patients with tuberculous meningitis (TBM), and compare these findings with conventional imaging and magnetic resonance imaging (MRI). SUBJECTS AND METHODS: Ten patients with definite TBM were prospectively recruited. The severity of TBM was graded into stage I to III. The patients were subjected to whole body (18)F-FDG PET/CT imaging and MRI brain...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27638826/-pulmonary-granulomatous-diseases-and-pulmonary-manifestations-of-systemic-granulomatous-disease-including-tuberculosis-and-nontuberculous-mycobacteriosis
#2
S Piel, M Kreuter, F Herth, H-U Kauczor, C-P Heußel
CLINICAL/METHODICAL ISSUE: Granulomas as signs of specific inflammation of the lungs are found in various diseases with pulmonary manifestations and represent an important imaging finding. STANDARD RADIOLOGICAL METHODS: The standard imaging modality for the work-up of granulomatous diseases of the lungs is most often thin-slice computed tomography (CT). There are a few instances, e. g. tuberculosis, sarcoidosis and silicosis, where a chest radiograph still plays an important role...
October 2016: Der Radiologe
https://www.readbyqxmd.com/read/27603341/increased-18f-fdg-uptake-of-heterotopic-pancreatitis-in-the-small-intestine-a-care-compliant-case-report
#3
Maomei Ruan, Min Liu, Lingxiao Cheng, Wenhui Xie, Libo Chen
BACKGROUD: Heterotopic pancreas (HP), a relatively uncommon congenital anomaly, is rarely noted during F-FDG positron-emission tomography/computed tomography (PET/CT) scan. METHODS: A 60-year-old woman was referred to our hospital due to a 10-day history of abdominal pain with elevated levels of serum amylase and lipase. Abdominal CT and ultrasound examinations were negative. In order to search for the cause, an F-FDG PET/CT whole body scan was suggested to an old woman revealing the presence of F-FDG accumulating nodule in small intestine...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27565136/a-method-to-assess-image-quality-for-low-dose-pet-analysis-of-snr-cnr-bias-and-image-noise
#4
Jianhua Yan, Josh Schaefferkoette, Maurizio Conti, David Townsend
BACKGROUND: Lowering injected dose will have an effect on PET image quality. In this article, we aim to investigate this effect in terms of signal-to-noise ratio (SNR) in the liver, contrast-to-noise ratio (CNR) in the lesion, bias and ensemble image noise. METHODS: We present here our method and preliminary results using tuberculosis (TB) cases. Sixteen patients who underwent (18)F-FDG PET/MR scans covering the whole lung and portion of the liver were selected for the study...
August 26, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27437932/observed-patterns-of-systemic-disease-on-pet-ct-scan-in-patients-with-presumed-ocular-tuberculosis-findings-and-hypotheses
#5
Salil Mehta
PURPOSE: To report the clinical, investigational and PET/CT scan findings of patients with presumed ocular tuberculosis and suggest a hypotheses for the pathogenesis. METHODS: Retrospective case review. Included were 10 males and 17 females with an age range: 23-71 years. RESULTS: Clinical findings include granulomatous or non-granulomatous anterior uveitis, intermediate uveitis, panuveitis, vasculitis, and multifocal serpiginous-like choroidopathy...
July 20, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27358601/an-old-enemy-not-to-be-forgotten-during-pet-ct-scanning-of-cancer-patients-tuberculosis
#6
Ahmet Taner Sümbül, Ahmet Sezer, Hüseyin Abali, Bilge Gültepe, Emrah Koçer, Mehmet Reyhan, Önder Tonyalı, Özgür Özyilkan
AIM OF THE STUDY: Positron emission tomography-computed tomography (PET CT) scan is commonly used in current medical oncology practice as an imaging method. In this study we present data from cancer patients who were followed at our clinic and suspected of having tuberculosis during PET CT scanning. After the biopsy, they were diagnosed with concomitant tuberculosis. MATERIAL AND METHODS: In this study, 14 patients who applied to our clinic and followed up due to cancer, and had PET CT scanning for the preliminary staging or further evaluation, were included...
2016: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/27217666/multiple-bony-metastatic-lesions-and-evaluation-of-primary-case-records-of-a-cancer-research-centre
#7
Deepak Sundriyal, Nikhil Shirsi, Arun Gera, Satish Bansal, Sumedha Kotwal, Ramesh Dawar
During 2012-13, we diagnosed 4 patients with extensive skeletal tuberculosis (TB) who were referred to us as cases of bony metastasis with unknown primary. Radiological investigations done outside favoured a diagnosis of disseminated malignancy. Positron emission tomography/computed tomography (PET/CT) scan performed in our institute for localization of primary lesion also suggested metastatic disease. There was no evidence of malignancy on histo-pathological examination (HPE) of the involved sites. The diagnosis of TB was established on characteristics HPE...
September 2015: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27162671/evaluation-of-pulmonary-nodules-in-asian-population
#8
Chee K Phua, Wen Y Sim, Kuan Sen Tee, Sennen J W Lew, Albert Y H Lim, Dessmon Y H Tai, Soon Keng Goh, Ai Ching Kor, Alan W K Ng, John Abisheganaden, Akash Verma
BACKGROUND: American College of Chest Physicians (ACCP) provides guidelines to manage pulmonary nodules. Pulmonary nodules however can be malignant or benign. Similar incidence of tuberculosis (TB) and lung cancer in Asian countries raises concern over the relevance of suggested guidelines in Asian population. There is little data on the pattern of clinical practice in the management of pulmonary nodules in Asian country (Singapore). Our study describes the current pattern of clinical practice in this area highlighting the variation in practice and discussing the potential reasons...
May 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27160950/diagnostic-value-of-f-18-fdg-pet-ct-in-patients-with-spondylodiscitis-is-dual-time-point-imaging-time-worthy
#9
Burcak Yilmaz Gunes, Cetin Onsel, Kerim Sonmezoglu, Resat Ozaras, Metin Halac, Fehmi Tabak, Sait Sager, Bilgul Mete, Haluk Sayman, Bedii Kanmaz
PURPOSE: In this retrospective study, we aimed to investigate the value of FDG-PET/CT in the diagnosis of spondylodiscitis (SD), the significance of dual time point imaging (DTPI) for SD diagnosis and the worth of SUVmax data for distinguishing tuberculous vs. non-tuberculous SD. MATERIALS AND METHODS: 32 patients with suspected SD were scanned with FDG-PET/CT. For quantitative analysis maximum standardized uptake value (SUVmax) of the lesion area was measured. Nineteen patients had DTPI of FDG-PET/CT...
July 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/26923625/evaluation-of-pulmonary-nodules-clinical-practice-consensus-guidelines-for-asia
#10
Chunxue Bai, Chang-Min Choi, Chung Ming Chu, Devanand Anantham, James Chung-Man Ho, Ali Zamir Khan, Jang-Ming Lee, Shi Yue Li, Sawang Saenghirunvattana, Anthony Yim
BACKGROUND: American College of Chest Physicians (CHEST) clinical practice guidelines on the evaluation of pulmonary nodules may have low adoption among clinicians in Asian countries. Unique patient characteristics of Asian patients affect the diagnostic evaluation of pulmonary nodules. The objective of these clinical practice guidelines was to adapt those of CHEST to provide consensus-based recommendations relevant to practitioners in Asia. METHODS: A modified ADAPTE process was used by a multidisciplinary group of pulmonologists and thoracic surgeons in Asia...
October 2016: Chest
https://www.readbyqxmd.com/read/26917899/fluorine-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-imaging-in-response-monitoring-of-extra-pulmonary-tuberculosis
#11
Arpana Arbind, Maria D'souza, Abhinav Jaimini, Sanjeev Saw, Yachna Solanki, Rajnish Sharma
Positron emission tomography/computed tomography (PET/CT) using 2-deoxy-2-(fluorine-18) fluoro-D-glucose ((18)F-FDG) has become a standard diagnostic modality in oncological practice. F18-FDG PET/CT is sensitive in detecting malignancy; however, specificity is low in differentiating infections or inflammatory diseases from tumor. In the present case study, we report a patient with postoperative carcinoma of tongue presenting with cervical lymphadenopathy and fever. The PET/CT scan showed metabolically active generalized lymphadenopathy, and a possibility of lymphoma was suggested...
January 2016: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/26792164/the-diagnostic-accuracy-of-integrated-positron-emission-tomography-computed-tomography-in-the-evaluation-of-pulmonary-mass-lesions-in-a-tuberculosis-endemic-area
#12
R du Toit, J A Shaw, E M Irusen, F von Groote-Bidlingmaier, J M Warwick, C F N Koegelenberg
BACKGROUND: Integrated positron emission tomography/computed tomography (PET-CT) is a well-validated modality for assessing pulmonary mass lesions and specifically for estimating risk of malignancy. Tuberculosis (TB) is known to cause false-positive PET-CT findings. OBJECTIVE: To investigate the utility of PET-CT in the evaluation of pulmonary mass lesions and nodules in a high TB prevalence setting. METHODS: All patients referred for the evaluation of a solitary pulmonary nodule or mass and who underwent PET-CT scanning over a 3-year period were included...
December 2015: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/26704732/18f-fdg-pet-ct-in-the-initial-assessment-and-for-follow-up-in-patients-with-tuberculosis
#13
Ingrid Stelzmueller, Helmut Huber, Rainer Wunn, Marina Hodolic, Michael Mandl, Bernd Lamprecht, Herwig Schinko, Franz Fellner, Andrea Skanjeti, Francesco Giammarile, Patrick M Colletti, Domenico Rubello, Michael Gabriel
PURPOSE: The aim of this retrospective study was to assess the value of 18F-FDG PET/CT in the initial evaluation and follow-up of patients with tuberculosis (TB). PATIENTS AND METHODS: Thirty-five patients (18 men) with pulmonary or extrapulmonary TB were included. Diagnosis of TB was based either on histology or microbiological assessment in 32 patients and was based on typical morphological features of TB in CT and improvement on antimycobacterial medication in 3 patients...
April 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/26585062/68ga-psma-hbed-cc-pet-for-differential-diagnosis-of-suggestive-lung-lesions-in-patients-with-prostate-cancer
#14
Thomas Pyka, Gregor Weirich, Ingo Einspieler, Tobias Maurer, Jörg Theisen, Georgios Hatzichristodoulou, Kristina Schwamborn, Markus Schwaiger, Matthias Eiber
UNLABELLED: In prostate cancer (PC) patients, the differentiation between lung metastases and lesions of different origin, for example, primary lung cancer, is a common clinical question. Herein, we investigated the use of Glu-NH-CO-NH-Lys(Ahx)-HBED-CC ((68)Ga-PSMA-HBED-CC) for this purpose. METHODS: PC patients (n = 1,889) undergoing (68)Ga-PSMA PET/CT or PET/MR scans were evaluated retrospectively for suggestive lung lesions. For up to 5 lesions per patient, location, CT diameter, CT morphology, and SUVmax were determined...
March 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26567238/tuberculosis-of-the-cavum-revealed-by-acute-facial-pain
#15
Thomas Gilbert, Christian Chidiac, Marc Bonnefoy, Tristan Ferry
An 85-year-old woman presented for assessment of recurring episodes of intense hemifacial pain, mimicking trigeminal neuralgia, associated with tinnitus. A necrotic tumour of the cavum with compression of the left Eustachian tube and skull-base invasion was discovered on brain MRI. Although the tumour was initially thought to be malignant, the histopathological findings on the biopsy were compatible with tuberculosis, later confirmed by the cultures. F-18-fluorodeoxyglucose positron emission tomography (PET)/CT showed an intense signal of the cavum, cervical and mediastinal lymph nodes, and also of two small nodules of the apex of each lung...
2015: BMJ Case Reports
https://www.readbyqxmd.com/read/26489149/-a-tuberculous-pseudo-aneurysm-of-the-abdominal-aorta-complicated-by-miliary-tuberculosis
#16
Toyoshi Matsutake, Kouji Hashizume, Naoe Kinoshita, Eijun Sueyoshi, Naomi Ehara, Reiji Nakano, Shintaro Yoshida, Kiyoyasu Fukushima, Hiroshi Kakeya, Shigeru Kohno
A 66-year-old man was transferred to our hospital on November 2010 owing to a diagnosis of miliary tuberculosis. Treatment was initially started with INH, RFP, PZA, and EB. However, PZA and EB were discontinued because of their adverse effects. Subsequently, chest radiographic and laboratory findings gradually improved. However, the patient experienced lumbago, which exacerbated towards the end of March 2011. An abdominal CT scan showed an abdominal mass at the L3-L5 level between the abdominal aorta and lumbar vertebra...
April 2015: Kekkaku: [Tuberculosis]
https://www.readbyqxmd.com/read/26429645/the-key-role-of-18f-fdg-pet-ct-for-correct-diagnosis-staging-and-treatment-in-a-patient-with-simultaneous-npc-and-tb-lymphadenitis-case-report
#17
Renato Micera, Nicola Simoni, Mario De Liguoro, Federica Vigo, Claudia Grondelli, Marco Galaverni, Massimo Roncali, Maria Pagano, Cinzia Iotti
AIMS AND BACKGROUND: The coexistence of tuberculous lymphadenitis of the neck region and head and neck cancer is extremely rare. In this clinical situation, the use of positron emission and computed tomography using fluorine-18 fluorodeoxyglucose (18F-FDG PET/CT) may facilitate the differentiation between malignancy and tuberculosis. RESULTS AND CONCLUSION: We present a case of an Eastern European man with nasopharyngeal cancer and concurrent tuberculous lymphadenitis...
September 26, 2015: Tumori
https://www.readbyqxmd.com/read/26284767/fdg-pet-ct-in-monitoring-antituberculosis-therapy-in-patient-with-widespread-skeletal-tuberculosis
#18
Na Hu, Yanlin Tan, Zhen Cheng, Zhu Hao, Yunhua Wang
FDG PET/CT imaging is a useful diagnostic tool in the evaluation of both neoplastic and inflammatory lesions and has a promising role in monitoring therapeutic response. We present a 50-year-old man whose initial PET/CT scan showed multiple foci of intense FDG activity in lytic lesions in the bones. A diagnosis of skeletal tuberculosis was confirmed after bone biopsy. Follow-up FDG PET/CT performed after 12 months of regular antituberculosis treatment demonstrated complete normalization of FDG activity in the bones...
November 2015: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/26180797/lung-and-nodal-involvement-in-nontuberculous-mycobacterial-disease-pet-ct-role
#19
Ginevra Del Giudice, Andrea Bianco, Antonio Cennamo, Giulia Santoro, Marco Bifulco, Carlo Marzo, Gennaro Mazzarella
INTRODUCTION: Systematic use of (18)F-FDG PET/CT has the potential to simultaneously assess both pulmonary and lymph node involvement in nontuberculous mycobacterial (NTM) lung infection. OBJECTIVE: The aim of the study was to evaluate the role of (18)F-FDG PET/CT in the assessment of both mediastinal lymph nodes and lung involvement in NTM patients compared with active tuberculosis (TB) patients. METHODS: 26 patients with pulmonary NTM disease were selected; six consecutive patients had undergone (18)F-FDG PET/CT and data was compared with 6 active TB patients...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26134119/initial-assessment-of-image-quality-for-low-dose-pet-evaluation-of-lesion-detectability
#20
Joshua D Schaefferkoetter, Jianhua Yan, David W Townsend, Maurizio Conti
In the context of investigating the potential of low-dose PET imaging for screening applications, we developed methods to assess small lesion detectability as a function of the number of counts in the scan. We present here our methods and preliminary validation using tuberculosis cases. FDG-PET data from seventeen patients presenting diffuse hyper-metabolic lung lesions were selected for the study, to include a wide range of lesion sizes and contrasts. Reduced doses were simulated by randomly discarding events in the PET list mode, and ten realizations at each simulated dose were generated and reconstructed...
July 21, 2015: Physics in Medicine and Biology
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